Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PTPN6 CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
FYN CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7524477 6730342
CSK PTPRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6672875 7507203
MRPL41 SMURF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18157088 6492033
UBC SMURF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
SMURF2 SQSTM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18157088 6492033
CRK PXN â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15308668 16000375
PIK3R1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23397142 25241761
SYK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9590268
PXN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23397142 25241761
GRAP BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6730720 8995379
GRAP PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10660596 23331499
GRAP PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7608146 23331499
VPS28 TSG101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YWHAZ GCN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ AFDN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
BCR AFDN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219918 17491594
ABL1 MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 G3BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
JUN ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9746785 15145216
GRB2 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
AP2M1 AP2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2B1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
GRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
API5 LTV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
BCR ATP2B1 â—¼   COLOCALIZATION 2.0 0.8 intact 5217253 15494376
TP53 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UNC119 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TCF7 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218278 16442529
LRRK1 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8010101 20697350
IGSF21 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TJP2 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217253 15494376
GIPC1 BCR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217253 15494376
BCR PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15050920 10579907
JUN BCR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9746785 15145216
IRF8 BCR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20237505 14656881
COPB1 BCR â—¼   COLOCALIZATION 2.0 0.8 intact 5217253 15494376
BCR CLTC â—¼   COLOCALIZATION 2.0 0.8 intact 5217253 15494376
BCR CFTR â—¼   COLOCALIZATION 2.0 0.8 intact 5217253 15494376
BCR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8978305 21602891
SYK CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220991 8621719
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
GRB2 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GTF3C3 CBLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB2 CBLB â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CBLB PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
CBLC KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
PIK3R1 CD80 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
FYN CD80 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
CD80 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
CD80 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN CD86 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
PIK3R1 CD86 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
CD86 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
CD86 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
STAT1 CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10773351
FYN CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11817894 15788770
UNC119 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDC42 RPS6KB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
CDC42 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438723
CDC42 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16381926
STAT1 CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19061877
YWHAZ CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
COMMD1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17183367 5219492
CREB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
CREB1 IL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21084670
CRK PNMA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PTEN CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
PTPN1 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6732073 9600099
CSNK2A1 HIF1A â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17382325 5219810
TP53 CSNK2A2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CSNK2A2 PTEN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
TP53 DDR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
YWHAZ DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
TP53 DYNC1H1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9781666 9627114
GRB2 DYNLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
EGR1 UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12903198 18174897
EGR1 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11502738 15449318
TP53 EGR1 â—¼   COLOCALIZATION 2.0 0.8 intact 5216887 14744935
EGR1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12384981
EZR YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
FES EZR â—¼   COLOCALIZATION 2.0 0.8 intact 18046454 6380309
FES PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8954948 8916957
FRK RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17318185 5219684
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
FYN MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
KIT GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16873377 18697750
GRB2 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212828 10913131
PNMA2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3CA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PTPN6 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10660620 6671678
GRB2 HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
HCK PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12029088 5215418
HCK TSG101 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12029088 5215418
HCK INPP5D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12029088 5215418
RUNX1 HHEX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28213513
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
HIF1A JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15794924 19828020
HIF1A RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19132225 20001745
HIF1A PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18340011 19648120
STAT1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19646959
STUB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19940151 25637186
YWHAZ HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
STAT5B HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19014541 22552610
HSPA4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
STAT1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9880553 10440232
YWHAQ HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSPA8 PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
YWHAZ HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
UTRN HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
TCF7 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 2088505 23954131
IL3 SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 1465135 8294403
RUNX1 IL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9036972
INPP5D SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 32323266 22267732
STAT1 IRF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19161415
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
UBC JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
KIT PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 7520444
LNX1 NAGK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 MAP1B â—¼   COLOCALIZATION 2.0 0.8 intact 18656471 6700545
PLCG1 MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PIK3R1 MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAP4K1 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
YWHAZ MTOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
MYC PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19602047 11509615
STAT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10637230
RB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 7838535
PIK3CA SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
SYK PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9720763 10592173
RAC1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9148763 10592173
PIK3CA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9148763 10592173
PIK3CG RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15009099 23331499
PLCG1 PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
YWHAZ PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10887121 8009576
PIK3R1 SOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
RASA1 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
RASA1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9020117 9743338
PTEN RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10753747
STAT5A PTPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12237455 6671710
PTPN1 RHOB â—¼   COLOCALIZATION 2.0 0.8 intact 14722096 6672086
PTPN1 STAT5A â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 12237455 6671710
RHOA PTPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16644720
PTPN6 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12220225
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
UBC RHOA â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5217531 15710384
YWHAZ SAMD4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SYK STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10825200
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
TJP2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
UBC YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CBLB PIK3R1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CREB1 TP53 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
GRB2 MAP4K1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CBL HCK â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
SYK PLCG1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 8657103
YWHAQ CBL â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8005785 11697890
KIT CBL â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25737303 16780420 15315962 8950973
UBC SQSTM1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5216530 12857745
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
GRB2 CSK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
CRKL EDC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
GRB2 VPS28 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RHOB P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
GRB2 1433B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
MYC 1433B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
GRB2 1433G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
JPH4 CSK21 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
COMD1 BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JPH4 CSK22 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CFTR RADI â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
RADI BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
APBA3 SCAI â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOS1 BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 8112292 7529874
JPH4 BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NAGK BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 32140074
RHOB BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
DDR2 CBLB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26826182 24631539
RAC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
MYC TFAM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC SYK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC RUNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
RHOB TULP3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 34079125
LNX1 UBC â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SOS1 YWHAZ â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
EGR1 TP53 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
CSK JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19818398 16740711
PTN6 GAB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11895767 11812650
GAB2 1433G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 19172738 33961781
PAXI FYN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16713569 10804218
PAXI RASA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10092539 16713569
CBL 1433F â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11697890 25036637 33961781 28514442
GAB2 1433F â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 19172738 33961781 31980649
EZRI BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 33961781 34079125
K1984 BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
AP2M1 TNKS2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RSPH9 BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CFTR BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17110338 15494376
SEC13 BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CBL BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20675402 8621719 14725908 8641358 19380743
TULP3 BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
BCR KIT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 8757502 25241761
KIT CBLB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12177062 15315962
MYC ERCC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33381997 17314511 29467282
STUB1 HSPA8 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16293251 5218068
MYC RRP12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30415952 35140242 29467282
RHOC RHOA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31871319 31980649
CFTR HSPA4 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
AP2B1 CLTC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CRK MAP4K1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ABL1 RB1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
GRAP SOS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 8647802 16713569
DOK1 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11071635 22974441
SOS1 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25241761 17474147 10025673
PTN6 BCR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9211920 9788431 27432908
ABL1 1433B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 25852190 15696159 16888623 28514442
BCR 1433B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 16045749
BCR 1433G â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29100370 28514442 33961781 16045749
1433G CBL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11697890 28514442 15324660 33961781
BCR PAXI â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 8641358 7534286
PAXI PTEN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23397142 11857088
ABL1 1433F â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 25852190 15696159 16888623 28514442
BCR 1433F â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 16045749
HCK BCR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9407116 8955135 12522270 12592324 9178913 10849448
DOK1 INPP5D â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
RASA1 GRB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12441060 16189514 16713569
MYC HIF1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15071503 28205554 28628118
STAT1 MTOR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19553685 25241761 12807916
UBC USP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CBLB P85A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19190244 10022120 9614102 11526404 10086340
P85A BCR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8781408 16219545 18346204
ABL1 PTN6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8114715 10574931 7512963 8692915 12468540 10488096
SIN3A CSK21 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17827154 22939629 32707033 26344197
CSK21 BCR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 32707033 32203420
NHRF3 BCR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 15494376
CSK22 DDX54 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23455922 26186194 32707033 27705803
LRRK1 ABL1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20697350 29513927 24947832
CRK BCR â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19380743 8978305 8943292
CFTR UBR4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
SOS1 HCK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12029088 23397142 17141806
HCK KIT â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24728074 11071635
HIF1A JUN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25879517 19738058 11739718
RASA1 KIT â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24728074 11071635
PLCG1 RASA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9743338 9020117 8977179
PTEN TP53 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
AP2B1 AP2M1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HCK SOS1 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CBL CSK â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19380743 11149930
CSK PTPRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19167335 7507203
GRAP KIT â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8647802 16713569
1433G P85A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15324660 17353931
KIT ABL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24728074 12374739
ABL1 HCK â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9407116 10849448
CREB1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 2138276
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
CBLC FYN â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CDC42 PIK3R1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
PSMD8 UBC â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
BCR ERCC3 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
GRB2 INPP5D â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
CSK FRK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 23455922 33961781
1433F AFAD â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 17979178
AP2M1 BCR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32203420 26186194 28514442 24189400 19380743
BCR RAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31871319 9535855
BCR RHOA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31871319 9535855
CRK CBLB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25814554 19380743
MYC DDX20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC UBC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 16996503 19131971
PTPN6 SYK â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HIF1A HSPA4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CFTR STUB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ABL1 RAD51 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CRKL PIK3R1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CBL YWHAQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CBLB CRKL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25814554 10022120
CRKL KIT â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11071635 9092574
CRK P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25241761 10962563 12878163 11418612 25814554 19380743
BCR PK3CG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7606002 8641358 25241761 9747873
JUN CSK22 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25609649 9685505
CSK22 PTEN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12297295 31685992
CSK22 BCR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 26186194 28514442 32707033
ABL1 PLCG1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17474147 1383690 10708759
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
HCK RASA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7782336 16189514
JUN RUNX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11274169 11641401
NAGK LNX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29892012 32296183 16189514 16713569
KIT PLCG1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BCR GRB2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CBL PLCG1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CRK PIK3R1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ABL1 PIK3R1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ABL1 DOK1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CSNK2A1 CSNK2A2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
GRB2 KIT â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
KCMF1 UBR4 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
KIT PIK3R1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
CSK PAXI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7529872 11695992 31980649 14665621
PAXI CRKL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11463817 7493940 8978305
GAB2 CRKL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9660791 10871282 11334882
CRKL BCR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10194128 15143164 9747873 8978305
PTN6 P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11160222 9452499 11337495 10488096
RAC1 P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8034624 31871319 32814053 7629060 12086876 26475863 25284480
P85A FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8394019 8294442 7520528 16713569 25416956
GAB2 1433B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 19172738 33961781
1433B AFAD â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 15324660 17353931
ABL1 1433G â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25852190 15696159 16888623 28514442 30021884
1433G 1433F â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15324660 26344197 26496610 28514442 22863883 17979178
CSK21 DDX54 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32707033 22113938 27705803
CFTR EZRI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26618866 10893422 29924966 31324722
FES BCR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8955135 7529874 10706130
CBL UBC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CBLC CRK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10362357 16713569 25814554 16189514 10571044
KIT STAT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25241761 9355737
GAB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
RAD51 TP53 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
DOK1 RASA1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
HIF1A UBC â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
SMURF2 PRICKLE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19379695
ABL1 CRKL â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
DOK1 CRKL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9822717 11071635 25814554 11553620
CRKL P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16982329 23397142 32203420 11418612 16135792 9461587
CRKL ABL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8524328 16955467 8978305 19823681 16443220 7926767 7493940 18835194 9710592 24412932 14604282 22286129 9820532
HCK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9636140 16809022 23109003
CBL P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9918857 19190244 17237826 7544353 10358153 8662998 9259313 8621719 14530346 15581361 7642581 15556646 9890943 16219545 10918571 8995243 16135792 9414268 8702998 8612729 19861161 16713569 11157475 19380743 11042121 16289966 9234717 16982329 8896416 9178909 33512474 8941725 11944898 25814554 9541596 9890970 9461587 9160881 7791764 9174058 8695807 24113870 11133830 11087752 18374639 9092538 10025673 9988765 11418612 15107835 21203488 11994282 10620516 11030146
ABL1 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8781408 8294442 16219545 16135792 19380743 17474147 1383690
P85A CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8034624 31871319 7629060 9381982 25284480
P85A KIT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17452978 10022833 1382595 7509796 25241761 12878163 24728074 16713569 9233773 7537096 11071635
PTN6 KIT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9528781 7684496 12614164
1433G AFAD â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 15324660 17353931
CSK22 CSK21 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19011756 23455922 24981860 26344197 25519132 25852190 26496610 30279146 26186194 27705803 28514442 32707033
CSK21 JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25609649 9685505 1516134 12628923
CSK21 PTEN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12297295 15717329 25047839 31685992
BCR AFAD â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34079125 17491594 12808105
RADI EZRI â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9501018 33961781 22939629 26496610 29568061 23414517 34079125
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
IRF8 ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20237505 24753251 14656881
PTPN1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9566916 16537444
HCK CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10092522 11896602 8995358 22974441 10799548 11239464 11994282 9890970
PTPN6 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11157475 12176909
CBLB PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11087752 17635922 10514377
CTCF CD80 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
PTEN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21385900
PTPN1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8940134 12799422
CSNK2A1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14675149 25862939
TP53 DDR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8977099 21398698
JUN EZR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19164283
RHOA EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 35267019 15659383
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
PIK3CA GAB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
KIT GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17452978 10022833 17904548 12444928 7523381 10377264 24728074 16713569 8950973 7523859 8647802
RASA1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12441060 16713569
HIF1A GYS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19828020
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
IL3 INPP5D â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9108392 9099679 10570274
STAT1 IRF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10092656 16918696 19074829
JUN RHOB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21565167 24636898
PTPN6 KIT â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 12614164 0265574 8312067
KIT SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8950973 16129412 10377264
KIT PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17496910 7520444
RB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7680889 10200487 9671466
STAT5A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17927978 12048235 12967477
MYC RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22159222 20383141 22235332
MYC SQSTM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PIK3CA SOS1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 21653832 16456001 10068651
PIK3R1 PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8596638 14665640 11733063
PLCG1 SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
PTPN6 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12220225 9211920
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
STAT5B STAT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15043997 17997837 14532269
STAT5A STAT5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21542777 15043997 17997837
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MRPL10 MRPL28 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
GRB2 SOS1 â—¼   RELOCALIZATION ✅ + 0.9 0.9 Signor 23452850
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
ABL1 CBL â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
TP53 ARHGEF39 â—¼   KO_DOWN_REGULATES ✅ - -0.92 0.91 PKG 28854368
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
SMURF2 UBC â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
GRB2 BCR â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5214841 11726515
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
SQSTM1 UBC â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
MRPL28 MRPL41 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
PLCG1 SYK â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
PIK3R1 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5217342 15556646
CRK EDC4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 19380743 31980649
HSPA8 STUB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
UBC WDR48 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CBL SYK â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
1433B CSK21 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 15324660 17353931
SOS1 FYN â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 17474147 16713569 9856337
MRPL10 MRPL41 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
CBLB GRB2 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
GAB2 P85A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 16253990 10871282 14530346 9660791 12506011 26839216 11334882 11782427 16135792 10068651 16219545
PTN6 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 8632004 10660620 25535246 10747947 16189514 11964172
1433G 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 15324660 24981860 26344197 24255178 17085597 28514442
1433F 1433B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 26496610 24255178 28514442 17979178
PAXI CRK â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10085298 16713569 26656091 12799422 12198159
PLCG1 GRB2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21706016 7629168 10940929 16038803 9020117 16713569 9281317 7516467
SOS1 PLCG1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10913276 10940929 9020117 16713569 17474147
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
RPS6KB1 MTOR â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 15905173
MTOR RPS6KB1 â—¼   PHOSPHORYLATION ✅ + 0.96 0.96 Signor 12782654
SEC13 SEC16A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
PSMD14 UBC â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
P85A GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7544353 8621719 18346204 7642581 16219545 32814053 7642542 20936779 16713569 19380743 21706016 7759531 8647120 25416956 9541596 9174058 11418612 7737969 9886492
CBL 1433B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 24255178 9367879 11697890 11157475 28514442 19380743
NHRF3 CFTR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15553237 11051556 12471024 18045536 12615054
DOK1 ABL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9822717 19823681 22974441 10688886 10567556 11071635 9008161
FYN CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9677430 8621719 12244174 7782294 10629042 119942 7642581 15556646 12231245 9311917 9535867 8626543 10799548 16713569 16503409 10092522 8900205 8995358 25814554 9890970 15190072 15208330 12941616 10829062 11239464 8662998 17094785
PLCG1 CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9234717 12941616 25241761 16467851 12061819 9712732 16713569 16503409 17372230 12803489
SOS1 CRK â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8810325 33961781 8943292 31980649 25241761 32203420 19380743 17474147
PLCG1 KIT â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14647465 25241761 24728074 16713569 7537096 11071635 7536744
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
CBLB UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
ABL1 CRK â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GAB2 GRB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HSP90AA1 PTGES3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TSG101 UBC â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MTOR RPS6KB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2B1 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
HSPA4 STUB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
USP1 WDR48 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CBL CRKL â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL CRK â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMD14 PSMD8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
TSG101 VPS28 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL PIK3R1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GRB2 SOS1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CSK FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
CSK FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1985196 8262983 11489946 16537894 9647655 25720756 18691976 10366594 19369195 1533589 1699196 7524477 16713569 15713745 14967142
CSK PTPRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7507203 19167335
CSK HCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11489946 16537894 10644735 11976726 14967142
CSK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17389395 18707149 27447856 11695992 7529872 9890993 14665621
CRK CRKL â—¼   PHYSICAL_INTERACTION 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
GRB2 CRKL â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRKL CBL â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
GRB2 CRKL â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK CRKL â—¼   SHARES_COMPLEX 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRKL CBL â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
FYN CRKL â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 11062502 12218089 12731048 15536084 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
CRK CRKL â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
ABL1 CRKL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
CRKL CBL â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 10426994 11062502 11353765 11385609 11447289 11526404 11579131 11687500 11907067 12670391 15169881 15308668 15536084 16000375 16076871 16713974 17397400 18250477 18287025 18835194 19109239 19454690 19909365 20189481 20805416 21149606 21826665 22464172 23087689 23523669 24751819 24795729 25960930 7682895 9314552
CRKL PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
BCR CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26500649 8978305 15143164
ABL1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 8978305 22581121 20841568 10837221 18768933 7493940 9710592 16955467 8524328 23331499 21199784 18794134 10592173 21051857 7926767 16443220 18835194 24165979 26500649 18809728 15459660 26192618 24412932 9053848 22286129 8083188 14604282 21435002 9820532 19823681
CRKL PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8978305 7493940 9710592 10592173 11463817
CRKL PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9092574 16135792 11418612 23397142 9461587 16982329
CRKL MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 9891069 11279207
PXN TUBGCP3 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
PXN TUBGCP3 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 12616499 15308668 16000375 16887996 17006514 18287025 18802074 22043013 24655141 29021139
CDC42 PXN â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 27248291 7761442 9831565
CRK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12198159 27686861 12799422 10329689 10592173 10085298 16713569 7525621 8662907 7537852
FYN PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7617039 10804218 16713569 23128389
ABL1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7615549 15817476 11774284 16254239 15107421 12408869 15572663 11695992 15592455 16094384 10823820 20841568 16713569 9603926 7537852
PXN CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12198159 27686861 12799422 10329689 10592173 10085298 16713569 7525621 8662907 7537852
PLCG1 GRAP â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 GRAP â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
KIT GRAP â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16129412 10377264 11809791 9872323 8647802
GRB2 GRAP â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PLCG1 GRAP â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
ABL1 GRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 23399893 8647802 7926767
GRAP PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8995379 23331499 9281317
GRAP SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 16293107 8995379 16713569 8647802
TSG101 VPS28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 26871637 19060904 26186194 11134028 15218037 25416956 21757351 11916981 31515488 16189514 32296183 12663786 14505570 24284069
MYC GCN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20936779 17353931 17314511 17093053
ABL1 CBL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 CRK â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
HCK ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 18775435 9407116 12522270 16787943 28087699 11847100 26473374 16912036 16076903 20841568 24708674 10849448
FYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522270 16787943 17570479 16912036 16076903 17474147 11847100
ABL1 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 23331499 26546517 9461559 15279774 15033353 19427856 11684015 19285032 20841568 15330855 15212693 10212258 12359302
ABL1 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8940193 17992189 20841568
ABL1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9525940 11494134 16713569 20841568 10829062 17389395 16955467 12604776 9890970 10391678 9195915 14725908 7925293 11997497 12522270 15556646 9102067 11239464 11994282 9174058 12475393 20675402 19380743 14604282 8626543 15212693 19823681
ABL1 DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11071635 10567556 12777393 9008161 15148308 15592455 25043303 18768933
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9407116 10405761 12522270 11780146 8622703 9178913 1712671 12124177 7529874 9467953 8955135 20841568 8112292 16912036 12543778 11376433
ABL1 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8940193 20841568
ABL1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19818398 18619508 10637231 20841568 14757045 15302935
ABL1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24836440 8940193 20841568
ABL1 MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11278340 17474147 9346925
ABL1 PTPN6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 8692915 8696915 14699166 12468540 10574931 7512963 16497976 20841568 14757045 8114715 10488096
ABL1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15039778 20841568 8112292
ABL1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21071413 23331499 10753870
ABL1 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9874796 20841568
ABL1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 8242749 7828850 16158058 9071815 20841568
ABL1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 10708759 19290927 12652307 1383690 16525023 8657103 20841568 17474147
ABL1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 100.0 1.0 Omnipath 8978305 9747873 9480991 19426560 17081983 23124138 16522685 16713569 20841568 18768933 8875975 25860930 21779437 19534553 16187300 17515907 21602891 16267043 20068231 10592173 17570479 8194526 7926767 11080615 25381819 12198159 9642287 15696159 18619508 18835194 11956190 22848689 11314030 9480911 19001122 19402756 20697350 12384576 24412932 7542925 11380621 12799422 19380743 12955086 17474147 17016520
BCR PIK3CA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15050920 20226962 11689702 11739186 15448205
BCR STAT5A â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 21330321 14660670 17698633 10935490
BCR STAT5B â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 21330321 14660670 17698633 10935490
HCK BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 9407116 12522270 10405761 12592324 19690332 9178913 7529874 17570479 16497976 8955135 16912036 18083107 10849448 12124177
FES BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 9407116 12522270 10405761 8622703 28819864 9178913 15302586 7529874 16497976 8955135 12124177
PTPN1 BCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9566916
BCR YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 17081983 18669648 18691976 20068231 9360956 16045749 98030561 19664995 19415658
HSP90AA1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
CRK CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
SYK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 72.0 1.0 Omnipath 16289966 15922744 9525940 19419964 11133830 33512474 18273061 10829062 10799548 10540342 10934191 7721825 12435267 11331248 12604776 9890970 11042121 10092522 11997497 12522270 9857068 9988765 15556646 11742985 15536084 8621719 9102067 22880054 10551821 11239464 10617633 11994282 10570266 12881521 9535867 15577829
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
HCK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 10092522 11994282 9525940 8995358 12604776 9890970 11896602 10799548 11239464 10934191
CRK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 8683103 16289966 8626543 8621483 9617486 16713569 9416834 8524328 10962563 8626404 9367879 8662998 12393469 11792427 15581361 9013636 15581362 9178909 9988765 18835194 8943292 20697350 9129019 19380743 25814554 9461587
CBL PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7517397 9712732 12941616 25241761 12061819 23109003 9234717 16503409 11709089 16713569 17372230 16467851 12803489
CBL PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 8641358 9119889 19380743 8621719 7629144 17635922 10514377
CBL KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9092574 17904548 25737303 8950973 15315962 17635922 10514377
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CBL PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 98.0 1.0 Omnipath 9092574 19190244 16289966 11406619 7642581 11133830 10358153 8941725 9234717 8612729 11157475 10620516 16713569 21203488 11418612 24113870 17635922 18374639 14530346 11526404 8662998 8995358 11030146 9890970 9541596 11042121 15581361 9890943 8080844 7791764 9178909 15107835 8995243 8695807 9988765 23109003 11944898 15556646 17237826 10025673 17722974 8621719 16135792 16107703 16219545 9461587 9160881 9414268 16982329 19861161 10514377 9918857 11087752 9092538 11994282 9259313 15790353 19531499 9174058 8702998 25814554 22315502 19380743 10918571 8896416
CBLB KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15315962 12177062 17635922 10514377
CBLB CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 8626404 19380743 12697763 25814554
CBLB SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12771181 16189514 27428901 10022120
CBLB FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15208330 16503409 32296183 25814554 8083187
CBLB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 10022120 25416956 21706016 31467278 32814053 9614102 17635922 11375397 8626404 16189514 21900206 20936779 27107012 12577067 10514377 19531499 10086340 29997244
CBLB PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 11087752 21780115 10488096 19531499 11526404 10086340 15032589 23109003 22880054 9614102 17635922 10514377
CD80 CD86 â—¼   PHYSICAL_INTERACTION 25.0 1.0 ACSN 10477595 11207245 11964292 12810107 14764699 15034038 15197224 17513775 17629517 18585785 20231889 20805416 21220452 22076556 22437870 23390297 24218453 25215878 25384214 25582338 26405600 7512027 7523569 8920882 9359474
IL3 CD80 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
STAT1 CD80 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
FYN CD80 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
STAT1 CD86 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
IL3 CD86 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
FYN CD86 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
CDC42 TUBGCP3 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10934474 11248548 11340065 15001467 15003621 15020669 15169870 15882626 16329184 17517963 17785506 18719708 19741094 21178402 22126964 22821962 27248291 7761442 9831565
PIK3R1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
CDC42 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7629060 8034624 9381982
CTCF CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19129223 22422629
CSNK2A1 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21930781 17289674
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
UBE2M COMMD1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16647857 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 21863050
CREB1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10471787 8647095 10403485 2140898
CREB1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11313407 12370343 17548609 12626549 15993752 12432566 8670878 8814256 11238674
JUN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2138276 1827203 18641343 8290251
CREB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16611888 25241761 21295542
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
PIK3R1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
CRK MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 35044719 11432831 9891069 9788432 16713569 17474147 11279207
CRK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10962563 35044719 25241761 19380743 12878163 25814554 11418612
CSNK2A2 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 26186194 27705803 25519132 19011756 26496610 25852190 23455922
CSNK2A1 RANGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16428860 18669648
CSNK2A1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 16107342 33760042 18723495 25823029 21840932 10866658 24766807 16690621 21779440 24706748 19662498 28263967 15987703 11035045 12077256 24047694 11707428 22413754 17444818 26832662 12297295
CSNK2A1 PTPRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9111075 10066810 15302935
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CSNK2A1 PTGES3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17081983 15040786 18088087 18166671 16094384
CSNK2A1 EGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8662759
CSNK2A1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 25609649 1846781 11948398 15378002 12531896 19413330 8654373 15302935 11075956 12628923 11896587 1516134 8464713 11971971 1651323 8137421 9685505 91332050
CSNK2A2 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17444818 19662498 15987703 16107342 11035045 12077256 11707428 12297295
CSNK2A2 PTPRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10066810 15302935
CSNK2A2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16083285 1088347 10348343 10884347 16552184 9315650 10747897
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
FYN DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11489946 16537894 11841937 11825908 15345598
KIT DOK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11071635 11825908
DOK1 RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10640270 11071635 10799545 9008161
EGR1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19915002 10656874 12560487 9756940 7673240 20680391 8773576 17142725
EGR1 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18506761 20448047
EGR1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17330857 17479230 20514024 12917634 17516844 15231710 18062928 18324520 11781575 20862322 16138117 21297666 20959484 16424010 15517593
EGR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9242687 17822668 15958557 12755686 16990849
EGR1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8035792 19426596 18928619
EGR1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15225550 14744935 11251186 16713569 12384981
SYK EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28306714 12387735 16189514 23338238
EZR FES â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18046454
FES KIT â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 16129412 7536744 12192036 10679268 7526158 9038210
FRK PTEN â—¼   DOWN_REGULATES ✅ - 4.0 1.0 ACSN 17218260 17218261 19597351 19652529
FRK PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17218261 29100343 19597351 23431463 22730341 26339505 17218260 24830552 19652529 22536248 19345329
SYK FYN â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN PTPRC â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 10591186 10648627 12218089 12414720 12731048 19290918 19909365 20814939 21378271 22683124 22863785 23620508 23886063 24440149 25312647 27192565 9738502
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
PTPRC FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 1985196 8980254 11909961 1464315 1533589 9535845 16713569 9368621 12589038
FYN SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7797565 7513017 17570479 10477689 9535867 16713569
FYN KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9038210 9799234 12374739
FYN SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17474147 16713569 9856337
FYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8395016 10586033 7682059 16713569
FYN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8294442 8394019 7515100 17570479 16713569 7520528 1652056
STAT5A GAB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
STAT5B GAB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
GRB2 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
SYK GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11895767 16371368 18950707
GRB2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 16371368 25416956 21706016 15143164 10391903 19172738 10913131 11027663 9973481 10973965 20936779 10068651 11882361 32296183 16199887 24737791 15010462 19523899 16253990 19380743 31515488 11782427
GAB2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 18950707 11334882 10068651 10982827 16253990 9973481 10871282 16135792 16219545 10973965 11782427 9885561 14530346
SYK GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
STAT5B GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
SOS1 GRB2 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 8810325 33961781 8695800 7510700 8626525 34407391 16520382 10570290 16906159 16893902 7642581 8816480 9447984 12577067 11964172 8112292 8493579 7664271 16713569 7516467 19380743 9009162 10207103 17474147 10477741 32062451 7629138 21706016 20473329 19323566 9872323 32203420 7514169 21988832 28166272 28514442 9716598 11997436 9344843 15192046 10716926 8479541 14679214 8943292 31980649 7629168 7559490 9478994 7527391 8188688 11960376 10025673 11726515 7773779 10319320 9569023 9797459
STAT5A GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 PLCG1 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 PLCG1 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
PTEN GRB2 â—¼   REGULATES ✅ 15.0 1.0 ACSN 10648629 10753747 11747822 12040186 15584861 15721744 16288286 16982858 17218262 19847259 22179046 22465479 23732914 24254977 25364523
KIT GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 24728074 8950973 7523381 10022833 7523859 8647802 16713569 17452978 17904548 10377264
SYK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11964172 16189514 22267732 10747947
PTEN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
GRB2 MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9346925 9891069 9788432 17474147 11279207
GRB2 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 145.0 1.0 Omnipath 9544989 9872323 7642581 15746962 11726515 8621483 23334917 16520382 11997436 21706016 10359574 8950973 7664271 16713569 16893902 16906159 21988832 19323566 9009162 10716926 11964172 7629168 9815779 10592173 9716598 8647802 28166272 7773778 7773779 18778683 8188688 10319320 8810325 9344843 23452850 11960376 8816480 10025673 7510700 8940013 12955078 9697839 12345678 10477741 8493579 8943292 12577067 7862167 9199344 8112292 7898932 10207103 8695800 19531499 10570290 7760801 20005866 19380743 9447984 8235613 8479540 7527391 14679214 8479541 17474147 7514169 7629138
GRB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9281317 15953601 7629168 9020117 16713569 10940929
GRB2 INPP5D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10660611 32323266 15456754 10748054 17043143 9108392 10900203 10068665 10891441 22267732 8723348
HCK STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10830280 12411494 17997837 18083107 11751923
HCK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 17081983 16497976 15592455 16126727 17389395 1689310 20068231 16153436 16038803 10586033 1708307 7682059 15144186 12601080 18707149 8885868 8657103 17016520
HCK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 21780115 11526404 15032589 23109003 12029088 22880054 10488096
HCK SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 12029088 23397142 17141806
HCK KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11071635
MYC HIF1A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
HIF1A PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835053 20724477 14726529 11359907 16682453 15833446 16982770 16618748
HIF1A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20404562 23059786 19845622 18616527 15780936 21303984
HIF1A HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15794924 14726529 20068160 18844219 18683594
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
RB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15674338
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
HSP90AA1 PLCG1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 17177598 16187797 15284455 16953218 17712310
STAT1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9880553 21430289 12940076 10440232
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
PTGES3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16565516 10642522 11447118 26804907 15916966 11413142 16403413 21988832 11812147 19875381 19740745 14761955 12077419 10811660 20039095 22806877 25036637 20048054 19996313 18285346 20661446 22315411 23022381 18172314 20159553 22729780 22504172 16289154 9817749 14987994 8114727
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
MYC HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1534087 14519204 1562593 10446203
MYC HSPD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19022255 12695333 14519204 21995449 11983916 11085504
PTPN6 IL2 â—¼   DOWN_REGULATES ✅ - 34.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 12176909 1238444 12393695 12421919 12707331 12773515 12917349 15169881 15240681 15699106 15713798 16204085 19833085 20363967 20435894 21469115 22483603 22513334 22683124 22952938 22955274 25355530 26667266 26755705 27474009 8976179 8986721 9751747 9765283
MYC IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8962093 10702306 12695333 1349016 9417120
JUN IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 20557936 12370343 10700231 12884855 8436291 9541574 8397339 1737937 9605137 8683110 21832163 9590239 7989759 9774418 16116194 8473495 8114694 10878360 10320367 9233628 7642615 17097050 7565732 8468462 8660843 7739550 8051409 1740667 19181930
RUNX1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17466384 22253733 17377532 21292764
STAT5A IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9817603 24587342 7479881 8683106 24550509 10022878 8943338 9121484 17911616 22854263 17182565 11435608
RUNX1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11997340 9036972 20506188 15735013 10023677 8180380
STAT5A IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15358227 14627821 24367002 10064602 12574125
IRF8 MYC â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10734131 11672593 11875494 11964313 12032143 12417340 12811837 16243976 16413922 16597464 17404308 17485448 22461508 23390297 24091328
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
RB1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10026157 9545246
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
KIT STAT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
PTPN6 KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 9528781 7684496 15526160
KIT STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10358045
KIT PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9092574 17496910 1382595 11071635 25241761 24728074 7509796 7537096 12878163 10022833 16713569 7520444 17452978 9233773
KIT STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11839738 10918587 11447289 11997436 12040186 21135090 15173823 7543024 15322115 6321473 11294897 10358045 7690989 15567848 19568798 12637327 14585353 15199124 17496910 11438544 25241761 10748192 7657660 12817007 9355737 19615955 11152457 10982844 7592750 16488589
KIT STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10358045
SYK MAP4K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11487585 17192257 11514608
TP53 MRPL41 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10321740 11313981 14743206 15077176 11429705 11158615 12374749 12384701 12024039 15192123 16009130 11919562 11313463 10777217 24388982 24006445 12702557
RAC1 MTOR â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
RAC1 MTOR â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
SQSTM1 MTOR â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15340068 16252010 20531300 21981924 25002027 26587781 28574505
RAC1 MTOR â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
RAC1 MTOR â—¼   DOWN_REGULATES ✅ - 56.0 1.0 ACSN 10702316 10722653 11274345 11756498 12150925 12408816 12906785 15749884 15755954 16469695 16556040 16678438 16713974 17404308 17461779 17604271 17680028 18000759 18372248 18481918 18492954 18570873 18925875 19022819 19027299 19143635 19143636 19151919 19225151 19244117 19446321 19568798 19706736 19720745 19864431 20027184 20138985 20338997 20547845 20805416 21157483 21474067 21533173 21621563 21708191 21981924 22504639 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 25062042 17510057 17081983 15208671 22873724 16922504 23077579 12087098 28270148 16286006 15896331 25356520 17664694 21790669 26919095 26313911 21561857 10567431 16099428 21977024 14679009 11940578 15899889 15388791 12829246 21980324 22751450 12604610 9465032 20068231 10601311 28122439 19302577 21602892 15718470 15631631 23273915 18669648 21307646 10579915 23261705 20169205 25936802 25486097 24411482 12586835 23342114 15809305 14560963 22472346 11279232 15760907 9271440 27856330 12370290 23486913 12782654 11914378 24795562 19877273 28242756 11500364 26698305 14993219 20459645 23029019 16964243 15212693 25505994
MYC PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23135913 19578399 12695333
MYC RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 20940401
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
TCF7 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
PTEN PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PIK3CA RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15854902 19225151 20097763 21123297 30021155 24990947 20068231 19079619 15809305 20599721 14623952 11279232 34518212 33800846 18669648
PTEN PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
TP53 PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10321740 19763735 21057544 18661553
PTPN6 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 21780115 11337495 11526404 15032589 9065461 11160222 23109003 22880054 10488096
SYK PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16921024 15536084
PTEN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PIK3R1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7629060 8034624 12086876 12515821
PIK3R1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17474147 19531499 25241761
SYK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17081983 19690332 8627166 16497976 15592455 16126727 17389395 19534553 1689310 20068231 10592173 16153436 16038803 1708307 7682059 15144186 9697839 7831290 7744830 12601080 8885868 8657103 17016520
RHOA PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12071848
PLCG1 SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15953601 12084069 7629168 9020117 16713569 10913276 17474147 10940929
RHOA PTEN â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10953004 11698448 11729192 11739775 11992112 12194823 12361600 12740575 12778124 14657501 14744429 15761148 15793569 17517963 18037882 18423981 20008297 20351293 20535745 21178402 21642958 21840487 22949611 24857661 24919149 26885855 27048821 27066895 7479854 9362522 9660866 9822605
PTEN RAD51 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218252 17218262 18716620 19847259 22179046 22465479 23732914 24254977 25364523
TP53 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22957312 15843377 12917634 21637289 17344317 12839924 11545734 18172008 19173293 20554748 19079342 14984207
TP53 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21336307 18431400 18339852 12620407 17409411 18172008 17823410 16713569 21518799 21483453
PTEN SOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16288286 10648629 17218262 12040186 15584861
PTGES3 STUB1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
PTGES3 STUB1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
PTPN1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10993888 12237455
PTPN1 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10993888 12237455
PTPN6 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12763134 11356834 10592173 16189514 10458769 10072516 10747947
USP1 RAD51 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 16531995 18082604 18082605 18931676 19075014 19217432 19264559 19622404 19686080 23589330
STAT5A RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16398215 12024032 15626738
TP53 RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513613 16322760 20802511 16398215 18769160
TP53 RAD51 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 8617246 11002423 16713569 16322760 16983346 9380510
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
TP53 RRM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12615712 16713569
SYK SOS1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
STAT1 STAT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
STAT1 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
WDR48 USP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 32951278 18082604 34128540 23116119 23463011
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501