Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AP2A2 MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10608864 10818153
ARRB2 KIF3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23074268 16908539
HRAS BRMS1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDK5 NUMBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EP300 COPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8414198 23441852
EP300 COPS2 â—¼   ACETYLATION ✅ 2.0 0.8 intact 8414198 23441852
COPS6 SMN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
COPS6 ZNF24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
COPS7B NEDD8 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CSNK2A2 PDCL â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15889144 16717095
CSNK2B PDCL â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15889144 16717095
DROSHA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
E2F6 POLD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15574595 18319725
EIF2B3 EIF2S2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16288713 15054402
MAP3K5 EIF2S2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24530506
GRB2 FLII â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP6R3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TULP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
RCOR3 GSE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HRAS NDEL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS RNF138 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS MCRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP3K5 MCRS1 â—¼   COLOCALIZATION 2.0 0.8 intact 22609355 8373100
MAPK1 MAP3K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16709866
MAX MGA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
STRN4 STRIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN4 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
KBTBD6 KBTBD7 â—¼   PHYSICAL_INTERACTION 809.0 0.8 STRING 36370105
RAD18 TMEM33 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
ARRB2 RAD18 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TCF25 DCAF5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 DCAF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21145461 18247557
DCAF7 RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27705803
DCAF7 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31753913 35016035
DOCK6 LRCH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32203420
JMJD6 HBS1L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JMJD6 ZNF24 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PRKAA1 PRKAG1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MRPS23 MRPS25 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
KRAS MAPK1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
AAMP WNK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CBL BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20675402 8621719 14725908 8641358 19380743
TULP3 BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
LRCH3 DOCK6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178 32203420
MAX E2F6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 25609649 27705803 29028833
SIRT1 EP300 â—¼   DEACETYLATION ✅ - 0.83 0.83 Signor 19047049
TULP3 JMJD6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
LRCH3 LRCH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178
LRCH3 LRCH2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178
MAX RING1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 29028833 27705803
TULP3 MCRS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
TULP3 OBSL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
TULP3 PML â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
TULP3 RAD18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 33187986
COPS2 GPS1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CUL7 OBSL1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
MRPS5 MRPS9 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
COPS3 GRB2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
BLK CBL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 8083187 8621719
MRPS18B MRPS23 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
MRPS18B MRPS23 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS23 MRPS7 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
MRPS18B MRPS5 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MRPS18B MRPS7 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
EIF2B3 EIF2S2 â—¼   GTPASE_REACTION ✅ + 0.84 0.84 Signor 15054402
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
OBSL1 CUL7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21572988 31343991 21737058 25752541
MEF2C EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21556048 9001254
TCEA1 UBR5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17643375 21127351
COPS3 NEDD8 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
GPS1 COPS6 â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 24421388
MAEA RANBP10 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
MCRS1 UBR5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23069210 17353931
NAF1 SNX33 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32296183 26496610
TULP3 RIOK3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23414517 33187986
NEB TTN â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
TULP3 BACH2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32296183 33187986
BYSL DNTTIP2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK9 MLLT3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HEXIM1 LARP7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ASCC2 TRIP4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK9 MEPCE â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COPS3 GPS1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
GPRASP2 TCF25 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
E2F6 PCGF6 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MGA PCGF6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RAB3GAP1 RAB3GAP2 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
LARP7 MEPCE â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDK5 CCNB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 25852190 26186194 28514442 23602568 32707033
COPS6 COPS3 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24421388
CDK9 LARP7 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
E2F6 MGA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BCR GRB2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COPS2 NEDD8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MEPCE CDK9 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17643375 23455922 29845934 33961781 24981860 27684187 26186194 24367103 28514442 23602568 32707033
PCGF6 E2F6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 26186194 27705803 11171983 28514442 16189514 22325352
IFT81 IFT74 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27173435 32296183 26186194 28514442
MEPCE LARP7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17643375 33961781 29845934 18483487 26725010 24778252 18281698
TULP3 NUMB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 33187986
RING1 PCGF6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12167161 33961781 32296183 24981860 27705803 28514442 22493164 22325352
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
AP2A2 ARRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
BCCIP CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
E2F6 DHPS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909625
E2F6 PRKAR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909625
EP300 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11796223 11062529 9001254
FLAD1 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LARP7 HEXIM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18483487 30824372
PDE4DIP KRAS â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MEF2C MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9069290 17210568 9988769
MAPK3 SORBS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15184391 17486060
MAPK3 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15093545
SMN1 PDE4DIP â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FLII LRRFIP1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
LARP7 CDK9 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 6613869 18483487
HEXIM1 CDK9 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 6613869 18483487
PCGF6 RING1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CSNK2A2 CSNK2B â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
GRB2 BCR â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5214841 11726515
CDK9 HEXIM1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
COPS2 CUL3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
MRPS18B MRPS25 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
MRPS25 MRPS9 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
MRPS25 MRPS35 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
MRPS25 MRPS7 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
GPS1 COPS5 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 7228517 19444310
GPS1 COPS5 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 24421388
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
MRPS25 MRPS5 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
GPS1 NEDD8 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
MRPS23 MRPS9 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
OBSL1 TTN â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
E2F6 RING1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11171983 24981860 27705803
MRPS23 MRPS5 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
RAD18 ARRB2 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
MRPS25 MRPS31 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MRPS31 MRPS5 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
PRKAA1 PRKAG1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CUL3 GPS1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MRPS18B MRPS31 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MRPS23 MRPS35 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RAD18 RNF10 â—¼   KO_UP_REGULATES ✅ + 0.97 0.97 PKG 28854368
MRPS7 MRPS9 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BYSL NOB1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
MRPS18B MRPS9 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS31 MRPS9 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MRPS35 MRPS7 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
MRPS23 MRPS31 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MRPS31 MRPS35 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MRPS18B MRPS35 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
MRPS31 MRPS7 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
ANAPC7 CDC23 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
IFT74 IFT81 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
COPS6 GPS1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
MRPS5 MRPS7 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
STRN STRN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPS3 COPS7B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS7B GPS1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS2 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS6 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MRPS35 MRPS9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MRPS35 MRPS5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
STRIP1 STRN4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS2 COPS5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 GPS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MRPS5 MRPS9 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
STRIP1 STRN â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS2 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 COPS3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS3 COPS5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS5 COPS7B â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS5 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ANAPC7 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 16123593 15279786 15917306
MAPK1 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18211802 19261619
MAPK3 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 28096473 24043311 18211802 19261619
CSNK2A2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877451
BLK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8621719 8083187
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
CDC23 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 16123593 15279786 15917306
CDK5 NDEL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 26944284 24785679 12796778 20068231 17242355 19413330 18669648 18809722
PRKAA1 EEF2K â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 11171059 22669845 11500364 14709557 15024086
PRKAA1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11020388 21940946 12379484 15006641 12590608
MAPK1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17623675 24530506
SIRT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15632193 19047049
TULP3 GPR161 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 23332756 20889716 19223390 19286674 24845016
GPR161 IFT122 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 23332756 20889716 19223390 19286674 24845016
TTC21B GPR161 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 23332756 20889716 19223390 19286674 24845016
NRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
HRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
IFT122 TULP3 â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12906858 17641202 19286674 19334287 20889716
IFT122 TULP3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12906858 17641202 19286674 19334287 20889716
KRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
NRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAPK1 SORBS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22028470 19369195 18691976 15184391 19690332 19413330 18187866 16964243 18669648 15302935
MAPK1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22935031 29416846 23293771 23316480 15093545
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
NRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAX MGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21988832 20936779 25609649 27705803 7954804
POLD3 RAD18 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RAD18 FN3KRP â—¼   KO_UP_REGULATES ✅ + 1.05 1.05 PKG 28854368
RAD18 TCF25 â—¼   KO_DOWN_REGULATES ✅ - -1.14 1.13 PKG 28854368
RAD18 EEF2K â—¼   KO_DOWN_REGULATES ✅ - -2.06 2.05 PKG 28854368
RAD18 RAD18 â—¼   KO_DOWN_REGULATES ✅ - -4.39 4.38 PKG 28854368