Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
RELA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17310108 10646503
ESR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
THRB PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16260719
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
RXRA NCOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17673910 5223765
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
RARA MED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17641689 5220098
ESR2 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
RARA ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9841885
THRB RXRA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220566 7746322
MED8 MED11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
THRB MED25 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17641689 5220098
MED12 MED15 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
RARA MED25 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 17641689
TRIP4 TF65 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16189514 12077347 21988832
MED12 MED24 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
CREBBP RXRA â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ASCC1 ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 25219498
BMI1 STAU1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
PPARG RARA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 32929351
MED25 MED13 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14657022 29568061
MED13 MED11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 29568061
ESR1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308691 21182205 19805454 20348541
TRIP4 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 29395067
MED15 MED27 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED15 MED11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED15 MED8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED11 MED27 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
MED23 MED27 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25281560
MED23 MED8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25281560
TRIP4 RS20 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 27684187
ALKB3 ASCC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ASCC1 TRIP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 26924529 32099016 33961781 26186194 27684187
ALKB3 ASCC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ALKB3 ASCC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25944111 33961781 26186194
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
MED12 MED25 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 20133760 26496610 33961781
MED12 MED15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 26496610 24981860 33961781 14657022 20133760
MED15 MED13 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 29568061 24981860
ESR2 TRIP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 29509190
MED28 MED15 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760 24981860
MED15 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
MED15 MED23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 25281560 33961781 24981860
MED15 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 24981860 26344197 33961781
MED25 MED17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657022 14638676 33961781
MED17 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197 24981860
MED28 MED11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 24882805 33961781 24981860 20133760
MED11 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197 24981860
MED24 MED27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
MED28 MED24 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760 24981860
MED24 MED8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22939629 33961781 26344197 24981860
MED28 MED23 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760
MED28 MED25 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15175163 33961781 20133760
ALKB3 TRIP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ASCC1 ASCC2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 26924529 32099016 33961781 26186194 29997253
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 17627277 5222291
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
ESR1 MED17 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 11867769
ESR1 MED4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
ESR1 RXRA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9717844 23403292 9121466
ESR1 MED27 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
MED4 MED10 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 25281560
MED4 MED10 â—¼   PROXIMITY ✅ 0.84 0.84 mint 25281560
MED23 MED17 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 25281560
MED8 MED17 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14576168 33961781 26344197 24981860
MED8 MED27 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 24882805 24981860 12584197 26344197
MED28 MED8 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15175163 12584197 24882805 33961781 24981860 20133760
MED13 MED27 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
MED24 PPARG â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9653119 16189514
NCOA1 NFKB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9556555 10847592
MED24 RXRA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9653119 16189514
RXRA MED25 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17641689
MED15 MED4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 25281560 26344197 24981860
MED12 MED17 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
MED13 MED8 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MED11 MED27 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
ESR1 RARA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9717844 25303530 25604459
MED15 MED27 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
MED15 MED8 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
EP300 NCOA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16713569 10973497 20368990 15688032 14722092 12208951 11113179
ESR2 MED12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21182203 11867769
MED12 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 20133760 26344197
MED12 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 27684187 22939629 20133760 26344197
MED12 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 22939629 20133760
MED12 MED11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26496610 33961781 24981860 22939629 20133760
MED13 MED17 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
MED17 MED13 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 29568061 26344197 24981860
MED13 MED8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 29568061 26344197
MED13 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 29568061 26344197
MED13 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 22939629 29568061 26344197
MED13 MED23 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12421765 29568061 33961781 24981860 25281560
RARA NCOA1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 5218295 16456540
ESR1 MED25 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24960263 17641689 31527615
RARA TRIP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 10454579 16713569
RXRA TF65 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10075655 25241761 16608838
MED27 MED17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 33961781 24882805 24981860
MED28 MED27 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15175163 24882805 33961781 24981860 20133760
MED25 MED24 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26344197 25792360 24882805 33961781
THB TRIP4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10454579 7776974
MED12 MED4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED12 MED27 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED10 MED13 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED13 MED24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED1 MED25 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED1 MED27 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MED10 MED24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ALKBH3 ASCC3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ASCC1 TRIP4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ASCC2 TRIP4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED11 MED12 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MED24 MED8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ALKBH3 TRIP4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ALKBH3 ASCC2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ASCC1 ASCC2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED10 MED25 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MED11 MED24 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED17 MED27 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MED10 MED23 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED17 MED8 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED11 MED4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MED1 MED11 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MED1 MED28 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
EP300 PPARG â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MED10 MED28 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MED24 MED4 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ASCC1 ASCC3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32099016 33961781 26186194 29997253
MED8 MED12 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12584197 26496610 33961781 24981860 27684187 22939629 20133760 26344197
ESR1 MED13 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11867769 31527615
TRIP4 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10454579 31527615
MED1 MED15 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MED1 MED8 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
ESR2 MED23 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29509190 21182203 11867769
ESR2 MED24 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29509190 21182203 11867769
MED25 MED15 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14983011 14657022 24882805
MED11 MED8 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
MED28 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15175163 20133760 33961781 24981860 25281560
MED27 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED24 MED4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED4 MED8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 25281560 26344197
MED4 MED23 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25281560 33961781 21293490
MED23 MED24 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 25281560 26344197
MED12 MED8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MED1 MED17 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MED10 MED15 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MED1 MED24 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ESR1 MED1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MED1 RARA â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MED10 MED8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
MED4 MED8 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CREBBP JUN â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED1 MED12 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED1 MED23 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED1 MED4 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED10 POLR2A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MED17 MED24 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ASCC2 TRIP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12077347 26924529 32099016 33961781 27684187 26344197
NCOA1 JUN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10847592 10567404 16713569 9642216
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
MED13 MED12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 29568061 26496610 33961781 24981860 27684187 20133760 26344197
MED28 MED12 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 15989967 33961781 24981860 20133760
MED12 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 30099503 26496610 20133760 33961781 25281560
MED4 MED13 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12421765 29568061 33961781 24981860 22939629 25281560
NCOA1 ESR2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11500849 10809226 11376110 14715875 11014206 10731636 15604093 19126643 12554772
NCOA1 THB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9751500 9121466 10454579 15604093 23975195 15249124 9171239 11435616
ESR1 TF65 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19350539 31527615 7651415 16497877 17932106 16331275
ESR1 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
MED8 MED1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 12584197 15989967 33961781 24981860 22939629 20133760 26344197
MED25 MED1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 14638676 15989967 17641689 20098423 25792360 33961781 14983011 14657022 20133760
MED1 MED11 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15989967 33961781 24981860 22939629
MED1 RXRA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21478865 15863722 9653119 11027271 11438648 10935544
MED1 MED27 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15989967 33961781 24981860 22939629 20133760 26344197
ESR2 MED17 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29509190 21182203 11867769
MED10 MED24 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 15989967 17404243 24882805 14576168 33961781 24981860 10882111
MED10 MED28 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15175163 24882805 33961781 24981860 20133760
MED17 MED28 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MED11 MED17 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 26344197 24981860
MED11 MED8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12584197 24981860 30021884 22939629 26344197
MED25 MED4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 25281560 14638676
MED23 MED25 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MED25 MED23 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24882805 25792360 33961781 14657022 25281560 26344197
ASCC1 ASCC3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MED1 MED10 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CREBBP RELA â—¼   ACETYLATION ✅ + 0.89 0.89 Signor 16382138
MED10 MED27 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
NCOA1 THRB â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MED10 MED12 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MED1 RXRA â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED27 MED4 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ASCC2 ASCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33139697 32099016 33961781 30875366 29997253 26344197
EP300 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27956703 21268080 21937452 24069158 11689449 14630807 11980644 10327051 12437352 12471036 24636898
EP300 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500849 17468099 10944516 14701856 11287611 19596656 32603375 11877444 12040021 10075656 30595551 22787115 12479814
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
EP300 TF65 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11585920 25074812 15171256 11533489 16291753 23999430 16135789 12403783 12456660 11567019 9096323 25400040 20154269 17982102 18397880 18280497 12419806 21187066 12471036 23811396 16713569 10235267 15192014 17692505 20333651 21483817 12960163 29706626
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
MED1 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23178929 17704298 10944516 30575522 15604093 19596656 12037571 10037764 30595551 17011503 16554032 9325263 17468099 22070604 15026545 11500849 30651555 11027271 11877444 10935544
PPARG NCOA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23178929 17704298 10944516 15604093 19596656 17312272 10731636 16373399 30595551 17011503 17468099 22070604 15026545 10339548 10347167 9121466 9041124 23975195 20717101 10848596 9744270 17449869 11500849 16713569 11027271 11877444 15888456 17513608 30813326
PPARG RXRA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22363753 16189514 12763030 10944516 31547433 30404011 20211142 35140242 25609649 17312272 23703729 7838715 19047629 12966085 22205725 14587029 10882139 30595551 30699358 9065481 21833030 9568716 34081964 21478865 9121466 23275339 17579352 19147680 26260846 16713569 12591919 10854698 30651555 32929351 23711995 11877444 15888456 18217139 19043829 17980149
RARA CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23321499 16417649 21110951
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
MED1 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 15989967 26496610 20098423 23322298 23563140 33961781 24981860 27684187 20133760 26344197
MED10 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 17404243 26496610 14576168 33961781 24981860 26344197 20133760 10882111
ESR1 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26487511 11867769 31527615
MED4 MED12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21293490 26496610 20133760 33961781 24981860 22939629 25281560 26344197
MED28 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 29568061 33961781 24981860 20133760
MED10 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 10882111 14576168 33961781 24981860 29568061 26344197
MED1 MED13 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 29568061 20098423 23322298 23563140 33961781 24981860 20133760 26344197
RARA NCOA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16606617 16713569 17641689 17475621 12665583 9121466 10454579 10760302 21478865 23975195 20338915 17363140 9192892 10082574 16456540 12138096 20543827
NCOA1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20608937 15604093 12738788 11003650 11250900 18451880 11867769 15140878 16282588 11165056 11376110 17627277 14715875 10731636 9259327 17363140 11113179 16606617 12630920 9121466 10760302 26487511 23975195 11682626 12714702 9192902 9192892 23874500 11358671 16713569 11014206 10454579 9773983 12554772 9427757 10598586 10409727 9774463 12574227 16957778
NCOA1 RXRA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20682316 21478865 9121466 11124027 15604093 7481822 10454579 10517671 17673910 23975195 11027271 17363140 23602807 15140878 9171239 10082574 11438648 10935544
MED24 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9653119 12837248 11867769 31527615
MED1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18391015 15886699 31527615 10760302 12738788 9653119 10770935 12837248 11867769
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
ESR1 NEK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
MED28 MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 15989967 33961781 24981860 20133760
RARA MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19377461 25303530 16713569 17641689 21478865 10760302 9653119
MED10 MED1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 15989967 24882805 14576168 33961781 24981860 10882111
MED1 MED4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 24882805 20133760 33961781 24981860 22939629 25281560 26344197
MED1 ESR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11500849 21182203 11867769 10770935
MED1 MED24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 20098423 9653119 33961781 24981860 22939629 20133760 26344197
MED1 MED23 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15989967 20133760 20098423 33961781 25281560
MED1 MED15 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18418385 15989967 20098423 33961781 24981860 14657022 20133760 26344197
MED1 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391015 15989967 20098423 33961781 24981860 17967894 20133760 26344197
MED10 MED17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 12584197 15989967 12149480 17404243 24882805 14576168 33961781 24981860 26344197 10882111
MED10 MED4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 15989967 24882805 14576168 33961781 24981860 22939629 25281560 26344197
MED10 MED8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 12584197 15989967 12149480 24882805 14576168 33961781 24981860 26344197
MED10 MED27 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 24981860 26344197
MED10 MED15 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 33961781 24981860 26344197
MED10 MED25 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781
MED10 MED11 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 12584197 15989967 24882805 14576168 33961781 24981860 22939629 26344197
MED10 MED23 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 15989967 24882805 14576168 33961781 25281560 26344197
MED1 MED13 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
MED10 MED17 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
MED10 MED11 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CREBBP RELA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
MED10 MED4 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
TF65 PPARG â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 30398029 33756273 14587029 23250430 18556801 23684777 17312272
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
MED11 MED17 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
ESR1 NR2F2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
RXRA RARA â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5212283 10698945
MED4 MED17 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 33961781 25281560 26344197 24981860
MED11 MED4 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 33961781 24981860 22939629 25281560 26344197
NFKB1 TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 20547752 8255759 27609421 29439025 16740634 21988832 24634218 14645533 11970949 35140242 15799966 25609649 15660126 21544861 29084252 14743216 8246997 34100597 22139845 17962807 9722548 2050119 22808155 20154269 21270162 17982102 24175631 25355951 23687337 11976329 15657065 8428580 20237821 12414801 10498867 22261743 16204234 16105840 14690596 11880271 33060567 8798655 16319923 21483817
RARA RXRA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 9415406 25241761 21988832 16540467 15604093 1310351 10698945 14521715 12052862 9582446 19345331 31700049 7760852 15528208 21478865 9121466 10882070 16769902 15171703 22539306 25303530 7705655 16713569 1314167 16224062
MED28 MED17 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15175163 15989967 24882805 33961781 24981860 22939629 20133760
ASCC2 ASCC3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CREBBP NCOA1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CREBBP PPARG â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RXRA THRB â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
MED1 PPARG â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ESR2 NCOA1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PPARG RXRA â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NCOA1 RARA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
RARA RXRA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOA1 PPARG â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NCOA1 RXRA â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
THB RXRA â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9415406 19211732 19422879 15604093 7746322 9368056 9582446 9162076 9171239
ASCC1 ALKBH3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12486230 22055184 12226667 12594517
ASCC3 ALKBH3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12486230 22055184 12226667 12594517
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
SIRT6 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19408108 19135889
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
RELA JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18174238 9468519 16713569 10488148
CREBBP JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8028671 10327051 2138276 9659924 9786917 16713569 17296604 8545107 18443043 16055710
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
CREBBP RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10542243 14597638 18241676 17138826 15140884 9096323 16713569 12456660 10454579 16382138 19608861 9806899 25314079 11931769 12163591 12881425 9659924 15171256 9548485 16291753 17362989 25733689 17434128 15334063 15806143 10235267 17296604
RXRA PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 12763030 25609649 20211142 11877444 16504037 17579352 16713569 9065481 22205725 23331499 22363753 10854698 19147680 19043829 12591919 9568716 10882139 10935544 17980149 26260846 21478865 14587029 23711995 9121466 18217139 31547433 7838715 19047629 23275339 21833030 12966085 17312272 11237216 15888456
NR2F2 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 23331499 10098492 20592862
NCOA1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10777539 15671023 12748280 11463834 14966289 19194461 9792627 18193094 11747826 17400812 17244199 9223281 10594042
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
MED12 MED13 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
MED12 MED13 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11001584 12417340 15279786 15337521 16007092 16413481 17000779 17303408 17565603 17660363 18590585 19879327 20144767 21327159 21330129 7575488 9216996
ESR1 XBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12954762 12047351 14605097
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8300756 8912864 8732679 11038749 15831516 15870697 10076999 9626663 18414489
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 17641689 15831516 9717844 9841885
RARA RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 15528208 19345331 16713569 16769902 21988832 23331499 14521715 15604093 21071413 10828175 10698945 18988627 12393611 25303530 16224062 25241761 1310351 21478865 17641689 7760852 9415406 9121466 7705655 9582446 15171703 10882070 1314167 12052862 31700049
THRB RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9582446 23331499 9368056 15604093 10677278 19211732 9162076 19422879 7746322 9171239 9415406
NR2F2 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 7479078 8119938 10900149