Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MYC AIMP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
CDC37 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CDC37 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PIN1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11774038 16713569
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
DHX9 DDX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
MYC DDX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 KRT16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12954631 16214953
EP300 DDX17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20663877
FXR1 HNRNPM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 TRAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 ENO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 ACTB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HSPA8 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IFIH1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0700544104 17600090
HSPA9 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DSP IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKE IFIH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0700544104 17600090
IRF3 IKBKE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20304918 21182093
NEDD4 ISG15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0710629105 18305167
ISG15 IRF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20308324 16914094
IRF3 ISG15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12354379
FUS MATR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
MYC ALB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17006931 8076602
MYC HSPA9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC EIF3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC TRAP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC EIF4A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18593934
MYC EIF4G1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18593934
HNRNPM NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 IL7R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YY1 NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16170350 9092633
RNF113A ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RPL4 SMARCAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA8 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DDX58 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
HADHA TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA9 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IFIH1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF6 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906941106 19955404
VCP CNOT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YBX1 CUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218767 16797541
SP1 YY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22553354
YY1 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21169469 23705901
YY1 PICALM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
IRF3 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6540704 18309294
SP1 IRF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22307793 22464952
IRF3 TBK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18583960 6948053
IRF3 TBK1 â—¼   COLOCALIZATION 2.0 0.8 intact 17599067 5220070
NCL PPP1CB â—¼   COLOCALIZATION 2.0 0.8 intact 12185196 8262810
EIF4A3 EIF4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ACTB TRAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 KRT16 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12954631
SP1 CALM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9348238 10945244
CALM1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9813038 8918462
KRT77 KRT17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GABARAP HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
IFIH1 RNF125 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0611551104 17460044
KRT17 KRT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RPS27A USP9X â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
HSPA9 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
EIF4B DDX3X â—¼   COLOCALIZATION 2.0 0.8 intact 8407815 22872150
LRRK2 NCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
SP1 TGM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10886517 21248772
SP1 MTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11368903 24010737
SP1 KRT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12024040
SP1 PPP1CC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9028876 12684058
DDX3X SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16818630 33627125
HNRNPM USP9X â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 CTSD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 6771293
NCL LTF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21575138 8175189
PABPC1 EIF4A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0914856107 20133758
G3BP1 EIF4G1 â—¼   COLOCALIZATION 2.0 0.8 intact 6665011 18005740
G3BP1 DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 30804210 22912779
EIF4G1 EIF3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8409681 23023399
EIF4G1 DDX3X â—¼   COLOCALIZATION 2.0 0.8 intact 8407815 22872150
EIF3K EIF3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18599441 0801313105
DDX3X EIF4A1 â—¼   COLOCALIZATION 2.0 0.8 intact 8407815 22872150
HSPA8 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
PPP1CC IFIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25865883 23499489
HSPA9 TRAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA9 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HNRNPM TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DDX3X TBK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18583960 6948053
HSPA5 DSP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TRIM25 IFIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18353649
SRP72 SRP68 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30649417 8388879
CPEB4 TOB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8173821 21336257
DDX5 SYNCRIP â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
EIF3J EIF4A1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EIF2S1 EIF3J â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
EIF4A1 RPS6 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
DOT1L RPS27A â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
CUL4B DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
DDX17 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 17226766 19995069 33742100 20663877
EIF3F EIF3B â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 24396066
HNF4A SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15651981 16713569 19115260
ERCC6 RPS27A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
LTV1 RPS27A â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
RPS6 SRP68 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
DDX58 RPS27A â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
TRAF6 AIMP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 27197155
BTK CDC37 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CFTR CDC37 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
STK4 CDC37 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24366813 23455922
CDC37 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16611982 24189400
CDC37 CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17525741 25036637
MYC CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
CRY1 ILF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23133559 25756610
CUL4B DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 34026424
CUL4B RBM14 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 28225217
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
SRRM2 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
DDX5 DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26344197
ESR1 DHX9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 21182205 19805454 20348541
ACTB EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33742100 21988832
HDAC6 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19344692 15102857 12718889 22778253 23133622
G3BP1 FXR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26777405
FXR1 DDX6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 29395067
NEDD4 ISG15 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18287095 18305167
ISG15 IRF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308324 32726803
MYC MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
CUL1 MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 21145461
MATR3 BTF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26344197 33644029
MATR3 RTCB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29511296 26496610
CUL3 MCM7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 26188516
MCM7 ILF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20808282 23764002
MYC RPS27A â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
MYC NXF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC DDX17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC ILF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC EIF3I â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
MYC DDX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC PKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25609649 29467282
MYC GFPT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
TRAF6 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 27507811
DDX58 IRF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18636086 16153868
DDX3X EIF3F â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527668 18628297
NEDD8 DDX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 24654937
NEDD8 DDX17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 24654937
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
CFTR USP9X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31324722 17110338
ARRB2 AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
CFTR DSC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
HDAC6 G3BP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18079183 21532619 32082291
G3BP1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26777405
G3BP1 PUM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 26777405
ESR2 EIF3I â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29509190 15604093
ESR1 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20308691 21182205 19805454 20348541
TDRD3 DDX3X â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18632687 29395067
TDRD3 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18632687 21988832
G3BP1 HSPA9 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
EIF3K RPS6 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
EIF3F EIF4A1 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
EIF2S1 EIF3K â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
RPL4 SRP68 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
EIF3F RPS6 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EIF3K EIF4A1 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
DCUN1D1 NEDD8 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
EIF3K RPS27A â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
EIF2S1 EIF4G1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
EIF4A1 RPS27A â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
FUS SYNCRIP â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
CDC37 DDX17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16611982 25036637 24189400
CRY1 CUL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 25756610 34237211 17463251 33961781
MATR3 DDX5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 DHX9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
ESR2 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11500849 18765668
MATR3 DDX17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 ILF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 DDX3X â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 ILF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 RBM14 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
HDAC6 MCM7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194 23703321
ARRB2 TRAF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19955404 16378096 25425640
EIF2S1 EIF3F â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
ESR1 EIF3F â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30573685 19805454 31527615
EIF2S1 EIF4A1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
EIF4B EIF4G1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
SOX2 USP9X â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23667531 31605775
HDAC6 CFTR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31501480 22069321 14675537
EIF3C EIF3J â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23623729 15946946 9822659
EIF3J EIF3I â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 14688252 33961781 26186194
ESR1 EIF3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30573685 19805454 31527615
ESR1 SRPK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
SREK1 JMJD6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CENPA NPM1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
KRT1 KRT14 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
KRT1 KRT77 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDX3X FUS â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KRT2 KRT77 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KRT2 KRT5 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KRT10 KRT77 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
KRT10 KRT5 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
SOX2 CDK1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23667531 30297536
SRPK1 DDX5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
DHX9 NXF1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
DHX9 PABPN1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
EP300 ILF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20808282 33742100
ESR1 GNL3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
MYC ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11839798 29467282
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
EIF3F EIF3J â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23623729 19615732
DDX6 G3BP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20639877 26777405 29395067
ESR2 ACTB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 21951318
FUS ILF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27460707 29884807
EIF2S1 RPS6 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
PABPC1 EIF4G1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 9857202 6548418
ESR1 MTA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 18451880 16645043
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
RNF113A SRRM2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
MAGOH SRRM2 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
FUS DHX9 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807
ILF2 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 20808282 30110629 33742100
TDRD3 FXR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29395067 24981860 18664458 24778252
PPP1CC RRP1B â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
CUL1 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
EIF3K EIF3J â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23623729 14519125
ESR1 RTCB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19805454 31527615 20348541
ESR2 SRRM2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 29509190 21182203 25604459
FUS DDX17 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27460707 29884807 26344197
CALM1 ESR1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
PES1 RRP1B â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
RPS27A ZRANB1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
RPS27A TRIM25 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
EIF2S1 RPS27A â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
HDAC6 RPS27A â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
EIF3J EIF4G1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CUL4B PPIA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
CUL4B DHX9 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
CUL4B DDX5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 28225217
ARRB2 NEDD4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23208550 18544533
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
CUL1 DDX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29395067 21145461
RAC1 LRRK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31046837 21454543
DDX3X EIF3C â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18628297 22323517
EIF3I ESR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10706629 31527615
SOX2 SRP72 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
DDX3X EIF3B â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
DDX6 YBX1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PABPC1 TOB1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
LRRK2 CDC37 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18367605 22612223 20642453 26355680 16321986 23075850
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
NXF1 DDX5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22658674 23143267 29395067
DHX9 ILF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22863883 22939629 23986595
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
EP300 IRF3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12473110 11940575 9660935 11314014 20604809 9488451 21903422
GNL3 PES1 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
MYC GNL3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 30415952 29467282
IRF3 MAVS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16153868 22908223 25636800 24379373 21903422
ESR1 ACTB â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 20308691 19805454 21182203 21182205 20348541
LARP1 ILF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 23986595
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
MAVS DDX3X â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 20127681 27980081
CNOT3 TOB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 18377426
CDC37 CHUK â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
IKBKE TBK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SYNCRIP YBX1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
KRT10 KRT2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
G3BP1 PABPC1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
KRT1 KRT2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EIF3J RPS6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
IKBKE MAVS â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
IFIH1 MAVS â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AIMP2 PARK2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 YY1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EIF3F RPS27A â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CAND1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDC37 LRRK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PRMT8 SYNCRIP â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CHUK CREBBP â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
EIF3C RPS6 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
IKBKE IRF3 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
IGF2BP1 IGF2BP3 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
IRF3 MAVS â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
RBM14 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11443112 33742100 16713569
SP1 EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15647279 19062177 10651903 11517158 23714681 10899165 16478997 11030335 24530506 34252870 28425985 31536933 32115405 17623675 10362258 16734381 17906698 22415975 12200149
FUS EP300 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 30110629 33742100
IKBKE TRAF3 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
PKP1 DSG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9606214 24981860 19136012
PKP1 DSC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14673151 24981860
DDX3X EIF3B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29395067 18628297
NR0B2 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9773978 11861507
ESR1 BTF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31527615 18025262
TBK1 MAVS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23028469 16153868 32366851 28346439 21813773 29125880 32511263 24643253 25636800 33372174 21903422 29743353
MAVS IFIH1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22623778 16127453 19881509 19416887 32612200 22301138 17600090 33372174 33649232 30193849 27312109 21903422
SREK1 SRPK1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 14559993 23602568
SRPK1 SRRM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25852190 32707033 23602568
DDX1 RTCB â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
DSG1 DSC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9606214 24981860 19136012
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MAVS TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NCL NPM1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HNF4A NR0B2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ILF3 DHX9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22751105 12946349 31536960 23986595 22939629
MATR3 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27460707 27731383 29884807 26496610
MYC SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11274368 18003922 17418410 15780936 32115405
RRP1B ILF3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29395067 33961781 19710015
DDX6 PATL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23851565 20584987 24778252 29510985 29395067 23535175
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
TRAF3 TBK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22330071 32324863 29125880 27135603 22792062 23986588 20174559 22079989 22908223 33608556 28049150 32779804 24763515 33372174 24622840 23717208 19380580 23308279 34084167 17991829 29920243 33187908 26928339 33411856 31404116
EIF3B EIF3J â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14688252 15946946 18628297
MAVS DDX58 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22114345 20007272 32612200 31433974 20071582 22022264 19164550 30193849 30267576 21903422 33649232 20554965 16153868 20080758 21102435 21292167 29053956 26494172 26061460 33372174 28594325 21844353 30558248 16127453 18200010 16177806 22301138 17190814 29263274 24478431 20434986 22623778 16585524 19193793 34544279 17709747 19454348 20406818 33976430
NR0B2 HNF4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16455805 11535594 20516075 28128295 16488887 15604093 10594021
RTCB DDX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24608264 22863883 33961781 27173435 24981860 29395067 22939629 30833792 26344197
ILF3 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27460707 29884807 16713569 11438536
MED10 MED29 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
MAP1LC3B NEDD4 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
DDX6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
EIF3F EIF4G1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CUL1 RPS27A â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EIF3F EIF3J â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
KRT16 KRT5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
EIF3I RPS6 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MED10 MED19 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MED19 MED29 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
MATR3 AIMP2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AIMP2 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ERCC6 CUL4B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12732143 16916636 22118460
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
DDX5 FUS â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
DDX5 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 33742100 12527917
DDX5 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 20308691 11250900 21182205 10409727
EP300 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527917 20663877
DHX9 NXF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22658674 20123736 16713569 18596238 10924507 22939629
EP300 IRF3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
MYC FXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC GNL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
IKBKE TRIM25 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
MYC MCM7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17353931 17314511 29467282 30415952
MYC MCM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PIN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26655473 29467282 15048125 19131971
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
ENO1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18490439 19219071 2191300
NDN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 26384308 24349431
MYC EIF3C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC HSPA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11983916 12695333
MYC YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12080043 18414489
MYC IRF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC EIF4A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RPS6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC EIF4B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC SMARCAD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC PKP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
ENO1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
TRAF6 MAVS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27348524 16153868 20080758 31806368 22908223 30527812 29125880 23545497 32511263 26385923 26221961 31390091 21903422
YBX1 ACTA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24832798 24446247 19261809
YY1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9238849 21852380
TRIM25 IRF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12692549 16153868 16846591
PIN1 IRF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19125153 16715065 16699525
CREBBP IRF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 ACSN 15265520 22331441 23422957
IRF3 IFIH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12692549 16153868 16846591
CREBBP IRF3 â—¼   PROTEIN_INTERACTION 3.0 0.9 ACSN 15265520 22331441 23422957
IRF3 TBK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23028469 31534043 25636800 16394098 30267576 21903422 22079989 15695821 32241891 20628368 18636086 15841462 19380580 28346439 18583960 25803835 17599067 12692549 19153231 22388039 24807708 19656901 22072751
IRF3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19349300 15355347 18309294
IRF3 TBK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23843640 20304918 18636086
DDX58 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28346439 26811330 16153868
PIN1 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16699525 19265157
CUL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
EIF4A3 SRRM2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
KRT16 KRT4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SP1 BLMH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21190945
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
TBK1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10783893 21138416
SP1 HSPA1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19336471 18434628 10704399
SP1 LTF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10845904 9666128
ESR2 CTSD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16219765 10037443
DDX58 TRAF3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
TRAF3 IFIH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
TRAF3 TRIM25 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
TRAF3 MAVS â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16858409 16306936 17190786
IFIH1 TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17020950 16306936 16858409
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
ESR2 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29509190 12630920 17991765 21182203 19022902 10706629 19746436 9473491
ESR1 DDX17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 11250900 21182205 20348541
TRIM25 TBK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
IFIH1 TBK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23453971 22619329 24722368
MED10 MED29 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15175163 14638676 24882805 14576168 33961781 24981860 26344197
MED10 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 12584197 15989967 24882805 14576168 33961781 24981860 21729782 26186194
MED29 MED19 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15175163 14638676 24882805 14576168 33961781 24981860 21729782 26186194 26344197
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
EIF3J EIF3K â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
DDX17 FUS â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ACTB CDC37 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT1 KRT16 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
KRT16 KRT2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
EIF3I RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EIF3J RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EIF3B RPS27A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
KRT16 KRT6A â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
PARK2 RPS27A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
IRF3 TBK1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ILF2 ILF3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
LTV1 RPS6 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
TBK1 IRF3 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 17599067 5220070
TBK1 IRF3 â—¼   PHOSPHORYLATION ✅ 0.92 0.92 mint 6948053 18583960
TBK1 IRF3 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 17599067 5220070
EIF3C RPS27A â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
RPS27A TRAF6 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
EIF2S1 EIF3C â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
DDX58 TRIM25 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
MAVS TRAF3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
DDX6 LSM14B â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NEDD8 RPS27A â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
DHX9 PABPC1 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
EIF3I EIF4G1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
EIF3I EIF3K â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 24981860 26186194 22939629
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TBK1 TRAF3 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EIF2S1 EIF3I â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
EIF3B RPS6 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TRAF3 MAVS â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 27348524 27980081 32366851 32324863 29125880 22792062 22022264 30267576 22079989 31806368 20080758 21200404 22908223 30527812 33608556 31390091 26221961 24622840 16858409 33582548 19419966 22901541 32511263 19893624 26519536 23545497 33411856
EIF2S1 EIF3B â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
EIF3I EIF4A1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
EIF3C EIF4A1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DDX17 DDX5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22365833 15298701 19995069 22863883 33961781 24581491 10837141 22939629
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
EIF3F EIF3I â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31527668 33961781 26186194 22939629 19615732
EIF3F EIF3C â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 18599441 31527668 33961781 24396066 26186194 24981860 23623729 22939629 19615732 26344197
EIF3F EIF3B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18599441 28514442 30573685 18628297 31527668 33961781 24396066 19245811 26186194 24981860 22939629 19615732 26344197
EIF3F EIF3K â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 24981860 26186194 23623729 22939629 19615732 26344197
ILF3 ILF2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16189514 20808282 23986595 33961781 17389650 26186194 29395067 22939629 26472337 11739746 21969602
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
EIF4G1 EIF4A1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219000 16932749
EIF3K EIF3B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18599441 18628297 24981860 22939629 26344197
EIF3K EIF3C â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18599441 22863883 33961781 24981860 23623729 22939629 14519125 26344197
SRP68 SRP72 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 16672232 8388879 33961781 22939629 26344197
COPS6 CUL2 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
EIF3I EIF3J â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
AIMP2 RARS â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
KRT1 KRT10 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
KRT14 KRT5 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
EIF3B EIF4G1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
MAVS TRAF6 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
EIF3B EIF3C â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 18599441 22939629 18628297 33961781 24981860 19245811 15946946 26344197
NEDD4 RPS27A â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
EIF3B EIF4A1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
DDX58 MAVS â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
EIF3C EIF3J â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
DDX6 PATL1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
EIF4G1 PABPC1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
EIF3C EIF3I â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 18599441 33961781 24981860 26186194 22939629 26344197
EIF3B EIF3I â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 14688252 18599441 18628297 22863883 33961781 24981860 16541103 26186194 22939629 26344197
DDX6 LSM14A â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
SRP72 SRP68 â—¼   PHYSICAL_INTERACTION ✅ + 0.99 0.99 Signor 30649417
EIF4A3 MAGOH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EIF4A1 EIF4G1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPS27A RPS6 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF3C EIF3K â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3B EIF3C â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3C EIF3I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CUL1 DCUN1D1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL4 RPS27A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3B EIF3J â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3C EIF3F â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3F EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3I EIF3K â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3B EIF3F â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3I â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3F EIF3K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL4 RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3B EIF3K â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SRP68 SRP72 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
FLG CASP14 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 21997417 20179351 17515931 23629652
CDK1 MCM7 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25398907 28831131 20150555 22266860
CDK1 DDX3X â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16280325 17379183
CDK1 EEF1D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 17081983 20166139 18767875 19413330 19664995 19415658 8051108 20068231 18452278 16189514 12551973 18669648 33521052 18691976 17287340 20068230 19651622 19691289 17924679 18212344
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
IRF3 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9463386 9488451 11940575 9660935 21903422 10024886 11314014
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
TRAF3 IKBKE â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12692549 15210742 16306936 16281057 14530355 17526488 17047224 14703513 23453971
IFIH1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16177806 17020950 15210742 15210743 16306936 16127453 12702806 16858409
MAVS IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 15210743 16127453 19153231 17020950 25636800 15210742 16306936 12702806 16177806 27419230 36056146 19546225 19380491 16858409 21200404 24706939 18207245 17468758 17327220
DDX58 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16177806 17020950 15210742 15210743 23950712 16306936 16127453 17468758 12702806 17327220 16858409 16281057
TBK1 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 18353649 17327220 16858409
TRAF3 IKBKE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 16177806 15210742 15210743 16306936 16127453 17468758 12702806 17327220 16858409 24763515
IKBKE IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 16127453 19153231 12692549 24722368 15210742 20532218 12702806 16380379 14703513 29800227 14679297 17706453 24396068 18440553 16281057 16625202 9463386 18818105 16199137 9566918 15695821 14739303 21138416 17526488 15212693 16914100
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
IKBKE TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17599067 16177806 15210742 15210743 16306936 16127453 17468758 12702806 17327220 24622840 16858409
IRF3 ISG15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19367472 8524823 12604599 9446577
MYC PIN1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC PIN1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11274345 11283614 16713974 16940750 17558397 17873522 19131971 19366350 19751508 19836308 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 22270359 23732914 25002027 26885856
MYC SLC1A5 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 19033189 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
ENO1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10082554 10528225 17595061 10802057 19846662 11134351 23421821 10403782 18490439 14506152 20886042 7880838 2005901 9074493 18070418 21559732 9119380 20412594 10681589
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC IGF2BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21779431 18414489 21252116
MYC NCL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10606642 24951594 12695333 14519204 25018006 11983916
CREBBP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17303408 15522869 12776737 20144767 17660363 16878156 15279786
CHUK MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
PIN1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 26655473 15048125 30723410 23716601
NPM1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22955283 31434245 16009132 12748172
PPP1R15A PPP1CC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 14670976 23331499 14718519 27629041 11564868
S100A9 BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518
S100A9 TRAF6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 18070982 15247281 21220427 12140561 12138165 8837778 19592497 18347055
BTK TRAF6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 18070982 15247281 21220427 12140561 12138165 8837778 19592497 18347055
TRAF6 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15836773
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
YY1 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16452489 15899857 15760841 8972185
TRAF3 IRF3 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15210742 16281057 14703513 9566918 17157040
MAVS IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17020950 25636800 21903422 16153868 22750291
TBK1 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 24549848 18583960 22072751 16380379 26811330 16127453 17618271 23478265 19153231 12692549 28618271 17599067 22388039 15841462 25636800 21903422 15210742 33990776 20532218 16699525 20170763 30842273 12702806 16306043 17018283 20628368 16914100 33411856 23746807 28159912 16394098 18356163 22904301 34379517 22810896 14703513 22750291 27548204 29800227 22079989 24056301 14679297 17706453 20511230 24396068 19211767 18440553 16281057 12524442 16625202 9463386 19893624 18636086 15749911 18818105 27125670 24807708 15695821 9566918 30496178 17526488 19656901 23028469 32351706 24371060 15367631 16199137 25803835 24622840 16155125
IRF3 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 59.0 1.0 Omnipath 10521456 17138826 19218087 10082512 15582653 21903422 17015689 23746807 23824799 16154084 15502848 25002588 9660935 14668346 17761676 12473110 20581830 9488451 25733689 18309294 9566918 10024886 17126870 16155125 15107417 17296604 11314014
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
PPP1CB EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21622569 9694816 9023344 12941928
SP1 KRT14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22911849 9154804 16273259
ESR1 KRT14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20188517 19435901 23870655 20578288
CALM1 RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22944912 21299499 21730051 9199170
NEDD8 DCUN1D1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 19617556 18826954 25349211 25314029 18206966 21940857 23201271 26906416 19250909 25531226 27030794
RNF125 IFIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17460044
RNF125 DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17460044
POT1 TERF2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
POT1 TERF2 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10581025 10850490 11349150 15231715 16166375 18680434 18828880 19454690 19965504 22064479 22634377 7502076 9326951 9822378
CUL1 USP15 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 USP15 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 USP15 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
EIF2S1 EIF4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 641056 592399 9732867 6853548
PPP1CC EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 21622569 9023344 27629041 9694816 12941928
CHUK CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21674813 17145710 14597638 17434128 22435559 12789342 27220480
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
EIF4B RPS6 â—¼   PHYSICAL_INTERACTION 31.0 1.0 ACSN 12150925 12408816 12844354 12867079 12906785 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
EIF4B RPS6 â—¼   SHARES_COMPLEX 31.0 1.0 ACSN 12150925 12408816 12844354 12867079 12906785 15755954 15905173 16286006 16469695 16679021 17368478 17680028 18391071 18492954 19022819 19339977 19568798 19597330 19864431 20647036 21157483 21177869 21233202 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
NEDD8 USP15 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 USP15 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 USP15 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
SP1 CTSD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11165043 7786196 8195246
SP1 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19540905 15651981 23307400
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 BTK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11254710 11779634 7721790 10362515 8562928
ESR1 CTSD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7786196 19383337 19569049 16219765 8524236 9731700 11165043 18414489 2350335 10037443 8195246
TRAF3 TBK1 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12692549 15210742 16306936 16281057 14530355 17526488 17047224 14703513 23453971
MAVS TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22901541 19893624 17020950 18818105 21200404 16306936 18207245 19546225 22844514 22792062 19193783 34610835 16858409
DDX58 TRAF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17020950 16306936 16858409 21844353
TRAF3 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 27135603 15210743 16127453 15210742 16306936 12702806 23986588 22792062 16177806 20389019 17991829 20174559 16858409 23717208 34084167 22330071 17468758 17327220 24622840
ESR1 LTF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16861234 8873065 10738912 10779508 15525592 8441416
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
DDX3X PABPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18596238 21883093 22872150
PABPC1 EIF4G1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19716330 17145710 16772376 12086624 9857202
TRIM25 DDX58 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 20406818 30902577 20818395 24478431 34471099 23950712 34452305 34529741 18353649 35075101 18948594 27122586 32513696 17392790
DDX58 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 16177806 17020950 15210742 15210743 23950712 16306936 16127453 17468758 16281057 12702806 17327220 16858409 21419663
DDX58 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 61.0 1.0 Omnipath 17145710 20554965 16127453 33372174 20007272 35075101 21419663 16585524 20406818 19052324 17020950 21903422 19164550 24478431 17190814 16713980 18200010 18948594 19193793 16177806 34544279 16153868 23843640 16785313 16301520 21844353 16125763 19036819 18977754 21102435 33976430 22301138 17709747 21200404 29263274 26494172 23499489 18207245 19881509 22844514 20080758
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
DDX17 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19995069 21182205 12738788 20348541 19718048 20663877 25604459
NR0B2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 21071413 9773978 18988627 11861507
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
IFIH1 TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16177806 17020950 15210742 15210743 16306936 16127453 12702806 16858409
MAVS TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 21813773 15210743 16127453 33372174 17020950 25636800 21903422 15210742 16753195 16306936 12702806 24643253 16177806 27419230 16153868 16858409 29743353 17468758 17327220
IFIH1 MAVS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19416887 22301138 17600090 17020950 19052324 21903422 16410796 16785313 16713980 23499489 16127453 33372174 16125763
NR0B2 HNF4A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11535594 12716764 24318876 14672953 11679424 21725089 12601360 10594021 16527247
NR0B2 HNF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11535594 23331499 15604093 21071413 20516075 16488887 16455805 14672953 10594021
NR0B2 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10648597 9773978 16189514