Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
LRRK2 NCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
FAM98B RTRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DDX1 RTRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
C2ORF49 RTRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RTRAF YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ESR1 AICDA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23181348 19139166
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
UBAP2L BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 25185265
YWHAZ CAND1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CRK RIN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DDX1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ DDX3X â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
RYBP FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FUS MATR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
YWHAZ HNRNPU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
LARP4B PABPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20573744
LRRK2 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
NPM1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YY1 NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16170350 9092633
RTCB YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
HSD17B10 TRMT10C â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
CUL1 MATR3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29884807 21145461
CSN5 RTCB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31950832 21145461
MLP3B MATR3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31006538 20562859
MLP3B RTCB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33545068 20562859
DDX1 HNRPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 22939629
RTCB HNRPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 26344197
BMI1 CN166 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
ASHWN RTCB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
ASHWN FA98B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
BMI1 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 RTCB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
MATR3 BTF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33644029 26344197
ESR1 CAND1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
CUL3 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22709582 21145461
CUL4B DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34026424 21145461
TDRD3 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29395067 18632687
ESR1 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20308691 19805454 21182205 20348541
ESR1 KLF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
TDRD3 FUS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 18632687
LRRK2 VDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 21370995
MATR3 RTCB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29511296
C2ORF49 RTCB â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
C2ORF49 FAM98B â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MATR3 HNRPM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 26496610 29511296
MATR3 DDX3X â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29884807 26496610 29511296
ESR2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18765668 11500849
DDX3X FUS â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
DDX1 RTCB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
LARP4B PABPC1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CSN5 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30587576 31950832 21145461 11337588 31253590
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RTCB FA98B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22939629 30833792 26344197
DDX1 FA98B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 24608264 22939629 26344197
ESR1 RTCB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31527615 19805454 20348541
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
CUL1 DDX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29395067 21145461
CSN5 CAND1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16861300 21145461
EP300 KLF4 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
ASHWN DDX1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 29395067 22939629
CUL3 ARMC5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 33130828 21145461
RIN3 CRK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32552912 25814554 17474147
SOX2 FOXC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
DDX1 RTCB â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CN166 RTCB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 30833792 26344197 24981860 22939629 24608264 22863883
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
CDK7 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10949034 31527615 15461668
FUS EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33742100 30110629 18509338
C14ORF166 RTCB â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
FAM98B RTCB â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
BTF3 RPL10 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CSN5 CUL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 22013077 22956996 19295130 18850735
CSN5 CUL4B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 34026424 23238014 19615732 21145461 26496610 23357576 26186194 30945288 28514442 19295130 18850735 31973889
CSN5 CUL3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 32047038 22013077 28514442 19295130 18850735 29897280
CN166 FA98B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24608264 22939629 26344197 30021884
ASHWN CN166 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 22939629 30021884
RTCB DDX1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27173435 30833792 26344197 24981860 29395067 22939629 24608264 22863883
MATR3 FUS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29884807 27731383 27460707 26496610
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MARK3 YWHAZ â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CSN5 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34237211 21903097 26265931 29103612 21249194 27774986 25144743 19615732 22767593 24973710 22959436 22956996 18850735 31950832 19141280 21145461 22013077 29863914 22474075 16036220
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CN166 DDX1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26344197 29395067 22939629 24608264 22863883 30021884
CUL3 CAND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 21249194 22013077 16449638 22405651 26286618 12609982
FN1 CRK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
ESR1 FOXC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25303530 18414489
ZEB1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21791114 18381457 17615296
YWHAZ GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
DDX1 FAM98B â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
YWHAZ MARK3 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5217040 15161933
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
C14ORF166 FAM98B â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
C14ORF166 DDX1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
NPM1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22955283 31434245 16009132 12748172
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
ZEB1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
DDX3X PABPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18596238 21883093 22872150
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
MARK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054