Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
BCLAF1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
FANCF MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAF1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
FOS MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
RAF1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
FOS MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588633 12134156
MAPK3 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19046355 9614189
SFN BRAF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN MAP3K2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN HDAC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SFN HDAC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
YWHAG STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8329523 22575644
YWHAH STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8329523 22575644
YWHAZ STK11 â—¼   COLOCALIZATION 2.0 0.8 intact 8329523 22575644
IKBKB TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23589370 33548094
SAAL1 MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ATP6V0C MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EIF3F YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAQ RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
YWHAG RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
PRKCZ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 10620507
HRAS VPS11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS BRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14724641
DAPK1 PIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DAPK1 CAPRIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DAPK1 EPHA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DAPK1 MARK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21311567
KSR1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9115393 9858547
MAP3K2 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB HDAC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8005492 10958686
YWHAB AKAP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MARK3 PRKCQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219779 17363905
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
YWHAZ PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10620507
IKBKB MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219779 17363905
YWHAG ARHGEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
ARHGEF2 RHOB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 16917499 18287519
CHGB MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAQ CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9543386 20068082
MAP3K2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
CLASP1 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG AKAP13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG HDAC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG MIEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG THRAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAE HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10737771 5212359
MAP3K2 YWHAE â—¼   COLOCALIZATION 2.0 0.8 intact 9452471 5221876
YWHAQ HDAC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8008084 18045992
HDAC4 YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8008084 18045992
AKAP13 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
NOL11 MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PMPCB MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
VPS11 MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TTR MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PNPLA2 MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CPSF4 MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ANKRD7 MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MARK3 ASB13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
G3BP1 CAPRIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
CAPRIN1 G3BP1 â—¼   COLOCALIZATION ✅ 0.8 0.8 mint 18005740 6665011
G3BP1 CAPRIN1 â—¼   COLOCALIZATION 2.0 0.8 intact 6665011 18005740
ESR1 YWHAQ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22329840
ESR1 EPHB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17685427 20484412
CAPZB CAPZA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MRPS27 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
DDX1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ PKP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216636 12941695
RTCB YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ TSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAB YWHAG â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
1433G STK11 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 28628118 22575644 28205554
YWHAB MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
HDAC7 YWHAG â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5217174 15324660
NRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 34591642
NRAS BRAF â—¼   PROXIMITY ✅ 0.81 0.81 mint 30194290
HDAC7 YWHAQ â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
MARK3 YWHAH â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
EPHA1 SAAL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOB ROR2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
1433T KSR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433G KSR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FOS ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
BMI1 RTCB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 CAPZB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 G3BP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 G3BP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
YWHAG MAP3K2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5217174 15324660
YWHAE HDAC4 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 8005698 11504882
NUAK2 MARK3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOB MARK3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
C43BP MARK3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
TMCC2 MARK3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LRC33 MARK3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 1433E â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
ESR1 CNBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 MARK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
RHOB MARK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
TMCC2 MARK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LRC33 MARK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433S 1433B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433B DLG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433G DLG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433G UBP21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F 1433S â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F UBP21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F DLG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
1433F SOGA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RHOB PKP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
RHOB DLG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31871319
1433T DLG5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KRAS MAPK1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
MAPT MARK2 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
ESR1 EIF3F â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30573685 19805454 31527615
HDAC5 1433G â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33961781 18951085 21081666
HDAC5 1433F â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21081666 23752268 33961781 28514442
CASQ2 MARK3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ESR1 1433Z â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33731348 19805454 25604459
HDAC7 1433B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 23752268 33961781 24255178 17369396
1433F ARHG2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 14676191 33961781
1433B ARHG2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24255178
MARK4 1433F â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14676191 16959763
1433T 1433S â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20618440 33961781 26186194
CHEK2 CDC25C â—¼   PHOSPHORYLATION ✅ - 0.83 0.83 Signor 12835754
BRAF MAPK1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
1433Z EIF3F â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15161933 17361185
DAPK1 CAPZB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
ESR1 HDAC4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19893013 16051668
MARK3 SOGA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
MARK3 DLG5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
MARK2 CAPZB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
MARK2 SOGA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
MPIP3 1433T â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15791647 27880917 15629715 28675297 9543386
BCLAF1 THRAP3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MARK3 YWHAE â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
MAPK1 RAF1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
IKBKB PRKCQ â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
BRAP KSR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18796711 14724641 18332145
YWHAH HDAC4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 18045992 8008084
YWHAZ HDAC4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5217040 15161933
MARK3 ARHG2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 29089450
ESR1 RTCB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19805454 31527615 20348541
MARK2 1433E â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 17979178 16306228 16968750
MPIP3 1433G â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 15791647 27880917 33961781 28675297 27432908 28330616
MARK2 YWHAZ â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
MARK2 YWHAH â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
UBP21 MARK3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19615732 22298430
UBP21 MARK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19615732 22298430
MAPT YWHAB â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 34591642
HRAS BRAF â—¼   PROXIMITY ✅ 0.87 0.87 mint 30194290
1433F KSR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17979178 33961781
MARK2 MARK3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 19615732
MARK3 MPIP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10557092 11333986 9278512 11551930 15319445 16968750 12941695 9543386
G3BP2 G3BP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26777405 26186194 29395067
MARK2 C43BP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 19615732 33961781
1433F HDAC7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 17979178 26496610 33961781 20224040
1433F PKP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 17979178 33961781
G3BP1 G3BP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MARK2 MTCL1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
NRAS RAF1 â—¼   RELOCALIZATION ✅ + 0.87 0.87 Signor 21779497
HDAC4 YWHAB â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CDC25C YWHAH â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
BRAF RAF1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23153539 28514442 31980649 18332145 20141835 23934108 31015455 11325826 23680146 20130576 26466569 22169110 33961781 34017080 28806393 20212043 25155755 22605333
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
HDAC5 1433S â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15923258 23752268 15367659
1433S MARK3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 15778465
1433F MARK3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 16959763 14676191 17979178 29089450 33961781 32707033 20642453
BRAF 1433E â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32707033 27034005 31980649 17979178 33961781 27684187
BRAF 1433F â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 27034005 31980649 17979178 33961781 32707033
1433G MARK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 16959763 17353931 33961781 15324659 32707033
MARK2 SOGA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20360068 26496610 23902687 32707033 19615732
DDX1 RTCB â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RHOB ARHG2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 31871319
ARHG2 1433T â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 29089450 14970201 33961781
1433E MPIP3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15791647 27880917 10330186 10681541 19331823 28675297 28094252
1433T PKP2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 12941695
CAPRIN1 G3BP1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HDAC4 YWHAE â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RAF1 YWHAH â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
SFN RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 15778465 5217604
EIF3F EIF3L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31527668 33961781 26186194 23623729 22939629 19615732 26344197
RAF1 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RAF1 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RAF1 1433F â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 11969417 31980649 11697890 10620507 17979178 26496610 8702721 16041367 33961781 16093354 25852190 32707033
1433B KSR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 24255178
YWHAB BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217174 15324660
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
HDAC5 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
1433F HDAC4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 31040226 18045992 17979178 26496610 33961781 27684187
HDAC5 1433T â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 15367659 23393134 20716686 33961781 21081666 22649097
1433T MARK3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15161933 17353931 29089450 33961781 32707033 20642453
PIM1 MARK3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15319445 33961781 26186194 32707033
YWHAQ BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217174 15324660
1433S BRAF â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27034005 31980649 28628118 15778465 28205554 27684187
1433T ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11266503 33731348 31527615
1433T MARK2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15161933 17353931 19011111 33961781 32707033 19553522
MARK2 ARHG2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29089450 22072711 19615732 21513698
1433S HDAC7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23752268 18339811 15778465
1433Z HDAC7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 15161933 33961781 20224040
HDAC7 1433G â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 17353931 33961781 15324660
HDAC7 1433T â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 23752268 15161933 16980613 33961781 16956611 17369396
HDAC7 1433E â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23752268 17979178 20224040 17369396
RTCB DDX1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24608264 22863883 33961781 27173435 24981860 29395067 22939629 30833792 26344197
ARHG2 1433G â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17353931 33961781 15324660
ARHG2 1433Z â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 22072711 15161933 14970201 33961781
1433B PKP2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 24255178
1433G 1433S â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15778465 33961781 26186194 15324660
1433G 1433F â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17979178 26496610 22863883 33961781 15324660 26344197
1433G 1433T â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17085597 20618440 22863883 33961781 15324660
1433F 1433Z â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17979178 26496610 20618440 22863883 33961781 26344197
1433Z 1433T â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26496610 20618440 22863883 33961781
1433Z MPIP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15161933 15791647 27880917 10681541 10864927
1433T 1433E â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 21988832 17979178 17085597 20618440 33961781 20936779
1433E 1433F â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 31536960 17979178 26496610 22863883 33961781 20936779 7615088 12507503 26344197
MPIP3 1433F â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 9278512 11969417 15791647 27880917 10330186 33961781 28675297 27432908 28330616
1433F 1433T â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 17979178 26496610 20618440 22863883 33961781
HDAC5 YWHAQ â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
BRAF YWHAQ â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MARK3 YWHAB â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MARK3 YWHAZ â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CHEK2 TERF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 26799419 19375317
CHEK2 RASGRF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17110335
MAPK1 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
BRAF MAPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK1 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
BRAF MAPK3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
MAPK3 YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 27503831 16939974 9560161
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
MAPK3 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 25846811
HDAC5 SFN â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8007093 15923258 0503275102
YWHAZ SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
YWHAG SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
SFN YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
SFN YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
TP63 MARK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
TP63 CDC25C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19861536
YWHAE RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8005785 11697890
1433B RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 31980649 10620507 7935795 7882972 25852190 19595761 7644510 11697890 12360521 32707033 8085158 8702721 10848612 16041367 33961781 16093354 12620389 24255178
1433S RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 11697890 16041367 15778465 16093354 25852190 26578655
1433T RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31980649 7760835 11697890 17353931 10620507 15618521 16041367 7479742 33961781 8663231 16093354 25852190 32707033 10757792
1433G RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 31980649 11697890 28628118 17353931 10620507 28205554 8702721 16041367 33961781 16093354 25852190 32707033 10433554
1433E RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 31980649 11697890 17979178 15459208 8702721 16041367 16093354 19608861 25852190 32707033 7644510
1433Z RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 20052757 10620507 7935795 25852190 9261098 12861023 8601312 14688280 16306228 28205554 22222486 20679480 7628630 19049963 11697890 10611249 9632690 17979178 9153224 15664191 7939632 32707033 8085158 28628118 10887173 16041367 16093354
YWHAB PRKCZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
YWHAG YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
YWHAB YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17085597 15324660
FOS CHGB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20359597
MARK2 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22072711
YWHAG BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 5217174 15324660
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
1433G HDAC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 23752268 25416956 31040226 17159145 18045992 17353931 11504882 33961781 27684187 15324660
1433S HDAC4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 23752268 16767219 15778465 27684187
HDAC4 1433T â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11470791 23752268 15161933 31040226 23393134 27684187 18045992 15964851 23444366 17470459 22466704 33961781 22649097
HDAC4 1433E â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 23752268 32296183 18045992 10869435 17979178 11114197 11504882 20936779 19608861 11486037 27684187
HDAC5 1433E â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 10737771 10869435 11114197 24841198 21081666
MARK3 PPM1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 12556533 211474200 8247257
MARK3 BRAP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19091743 14724641 18332145
1433B MARK3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16959763 17353931 29089450 33961781 24255178 32707033 20642453 15324660
1433G MARK3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16959763 17353931 29089450 33961781 32707033 20642453 15324660
MAP3K2 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11343802 23331499
1433B BRAF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 27034005 10931830 32707033 31980649 17353931 33961781 24255178 12620389 27684187 15324660
1433T BRAF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 27034005 32707033 31980649 18332145 17353931 17979178 31015455 33961781 27684187 15324660
1433G BRAF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 27034005 32707033 31980649 28628118 17353931 17979178 33961781 28205554 27684187 15324660
1433Z BRAF â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 27034005 32707033 15161933 31980649 28628118 17353931 17979178 26496610 33961781 28205554 27684187 15324660
ESR1 AGL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESR1 CLDN4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
PRKAA1 HDAC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21892142
1433Z MARK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15161933 14676191 16306228 33961781 15324659 32707033 11257119
MARK2 1433F â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16959763 14676191 17979178 19553522 33961781 32707033 19615732
MARK2 HDAC7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16980613
1433E 1433G â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31980649 21988832 31536960 17979178 17085597 33961781 20936779 12507503 26344197
1433Z 1433G â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 28628118 31536960 26496610 20618440 22863883 33961781 28205554 26344197
1433Z 1433S â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15161933 17361185 20618440 22863883 33961781 26186194
HDAC4 YWHAQ â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
RAF1 YWHAQ â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MAPT YWHAZ â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
KSR1 1433Z â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 28514442 9115393 9858547 33961781
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
YWHAH MARK2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 19553522 8009002 0803887
YWHAZ MARK2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 5217040 15161933
1433G PKP2 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 28514442 33961781 15324660
CDC25C YWHAB â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
YWHAH RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8005785 11697890
CDC25C YWHAE â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
MARK3 1433E â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 17979178 29089450 16968750 16306228 32707033 20642453
YWHAZ BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217040 15161933
MAP2K2 MAPK3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
NRAS RAF1 â—¼   PROXIMITY ✅ 0.93 0.93 mint 30194290
YWHAZ MARK3 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5217040 15161933
BRAF KRAS â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
BRAF RAF1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
YWHAG HDAC4 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5217174 15324660
HDAC5 1433B â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 23752268 10869435 33961781 24255178 21081666
NRAS RAF1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
MRPS23 MRPS27 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
BRAF NRAS â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
YWHAB RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 19595761 8009093
1433Z HDAC5 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 23752268 15161933 33961781 21081666
MARK2 1433B â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 16959763 33961781 24255178 15324659 32707033
CDC25C CHEK2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
HDAC4 YWHAG â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
BRAF HRAS â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CDC25C YWHAZ â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
MAP2K2 RAF1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
BRAF MAP2K2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
YWHAZ RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 14688280 309620200 8006563
RAF1 BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 8396417 22510884
RAF1 MAP2K1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7014125 19197339
HDAC4 1433B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 23752268 31040226 10869435 33961781 24255178 27684187 10958686
1433Z MARK3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 15161933 16959763 14676191 29089450 16968750 26496610 16306228 33961781 25852190 32707033 20642453
1433F 1433B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17979178 26496610 33961781 24255178 26344197
1433G 1433B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17085597 33961781 24981860 24255178 15324660 26344197
1433T 1433B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 17085597 20618440 22863883 33961781 24255178
1433Z 1433B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31536960 26496610 20618440 33961781 24255178 26344197
1433B 1433E â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31980649 31536960 17979178 17085597 33961781 24255178 20936779 12507503 30135474 26344197
1433B MPIP3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 15791647 16205633 27880917 10681541 15284440 33961781 24255178 28675297 19470455 28330616 12937170
1433Z 1433E â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 19766566 28514442 31980649 21988832 31536960 17979178 16376338 26496610 20618440 22863883 33961781 20936779 22939629 26344197
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
HDAC4 1433Z â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 23752268 31040226 15161933 15964851 11504882 33961781 11486037 27684187
MAP2K1 RAF1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
KRAS RAF1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BRAF YWHAZ â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
HRAS RAF1 â—¼   PROXIMITY ✅ 0.98 0.98 mint 18273062 6540139
RAF1 HRAS â—¼   PROXIMITY ✅ 0.98 0.98 mint 18273062 6540139
KSR1 MAP2K1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
MAP2K2 MAPK1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RAF1 YWHAZ â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CAPZA1 CAPZB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EIF3F EIF3L â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
BRAF MAP2K1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CHEK2 CDC25C â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11438669 15459660 15810020 15867354 17296736 17464182 17568790 18048416 18566216 18756267 18931676 18971944 19686080 19788416 20019063 20126263
CHEK2 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20159774 23550703 20466736 21215781
CHEK2 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 18566216 19165865 29774099 27427153 29302370 15810020 18321553 29425806 15707569 20860841 21152443 10681541 12711320 12505356 11551930 9836640 11333986 11583839 17097061 23880065 26485758 20637859 10744722 11240139 26633535 9889122 20599567 20068231 23788960 16481012 25914884 20126263 23705030 15791647 9278511 21924579 15629715 27801830 10097108 12814430 28094252 11313986 12941695 11728459 11053450 9278512 10557092 15459660 10435585 27038604 15150265 17464182 9543386 17568790 15282313 16488126 12478465 12835754
MARK3 MAPK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
NRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
RAF1 MAPK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
HRAS MAPK1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MAPK1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK1 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAP2K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 21675959 11704645 9694850 17081983 7565670 12750173 19690332 12932319 11823456 18799465 15592455 11337027 18083107 21365009 12788955 11134045 19219045 17389395 9447970 15342917 23331499 19534553 17569879 7559390 23047924 8226933 8223433 17272394 15851026 15811950 19494114 18988627 18669648 11549292 23519423 19541618 18691976 1381507 16293107 17906627 11986622 19933846 8376945 19053285 16094384 11971971 17192257 11136732 11948414 8388392 7898932 9731057 11730323 18039929 11118451 19369195 12920017 15951569 15466214 10746662
KSR1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 9858547 8248196
MAP3K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8226933 15315965 17052767 11971971
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
PRKCZ MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 9614189 9832145 12387894 12766916 12765608 12414518 19413330 1330687 24116116 19415658 15302935 33961674 9716264 34493616 31178717 28066266 15324364 31065832 25573097 12801934 29298849 16165272 15883264 16115884 8166686 33952699 9565682 11181841 34536819 10737616 7566346 18315566 9771888 29760653 34480088 24301651 15542598 18055457 12226093 7488031 9199504 18510355 21731772
MAPK1 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 15616583
MAPK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17081983 18767875 15849194 19690332 11409918 14654779 23331499 23180781 8226933 20068231 18988627 21917714 18669648 19541618 18691976 16407412 19933846 9922370 15664191 8388392 19651622 10801873 8349614 18775330 9604935
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
MAPK1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 14654779 21478863 19541618 16508002 19710016 19933846 15664191 29335436 8621729
MAPK1 STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 25679014 25846811
MAPK1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 12134156 20506250 15547943 8248197 7816602 15084594 12697810 8226933 20068231 18452278 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 21098038 9604935 11274345
MAPK1 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18211802 19261619
KRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
NRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MAPK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
RAF1 MAPK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK3 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK3 MARK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
FGFR1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
MAP2K2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 19901323 17081983 11704645 9694850 12750173 1411546 19690332 12932319 18799465 16497976 18083107 11134045 8626767 9006895 17389395 19219045 15342917 9447970 16887817 23331499 17569879 7867743 7559390 21071413 19534553 8226933 20068231 8223433 17272394 93330262 15851026 15811950 26987942 18988627 19494114 18669648 19541618 11242034 15466476 18691976 1381507 17906627 11986622 19933846 8376945 11971971 17192257 11136732 11948414 7898932 7687743 9731057 19651622 11730323 16464493 18983981 11251083 11118451 15580310 19369195 18707149 12920017 15951569 15466214 10746662 15212693
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
KSR1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 8248196
PRKCZ MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK3 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 17018293 12134156 20506250 15547943 7816602 15084594 12697810 8226933 12738796 16393692 17255949 17439715 15187187 19541618 23109003 19565474 17722974 17052211 7588633 8545107 16055710 8388392 18039929 12972619 18775330 26725323 21098038 9604935 11274345
MAPK3 ARHGEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 28096473 24043311 18211802 19261619
MAPK3 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 25241761 15616583 26769850
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK3 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27342992 23405013 18411303
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
MAPK3 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 14654779 23331499 19541618 18691976 16407412 19933846 9446616 9922370 15664191 18988627
MARK2 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 7706316 28066266 9108484 23666762 23001711 17360912 17573348 21311567 22952452 24251416
TP63 SFN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12640112 17404570
RAF1 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16093354 26578655 35044719 16041367 15778465 11697890 25852190
SFN YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
PRKAA1 STK11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 14511394 15579580 8779952 14985505 14614828 11018120
PRKCZ STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11853558 18250273 19414597 16407220 18321849
STK11 MARK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 17192257 14676191 14976552
STK11 MARK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19369195 12879020 17192257 14976552
STK11 MARK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 14976552 19369195 28711359 22238344 17573348 17192257
STK11 PRKAA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 16434556 25792737 14985505 14976552 20489196 21062936 20656472 20616029 17255104 16041368 25696921 21399626 12391032 20160076 17244528 15980064 17054914 22517326 14532170 21918180 28694351 18693249 26771234 20801214 16600998 18195011 28723898 16912160 22039048 26068970 14614828 19884317 25679763 22575644 19197243 27864418 30022161 25683918 18303014 17287464 15327994 12764152 16054095 15509864 26506235 14511394 27181208 28625738 25874865 8910387 17276402 26247630 21680840 19414597 23418352 24289924 15383373
STK11 NUAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18083107 14976552 17242355
HRAS RAF1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RAF1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
RAF1 YWHAB â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 HRAS â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 MARK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
RAF1 HRAS â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 YWHAB â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
FOS RAF1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
RAF1 HRAS â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
KRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 10958680 12750173 9516156 12932319 9665134 10783161 8805624 1386920 1639773 8340422 8601312 19595761 23331499 16041367 21071413 8332195 9446616 10882715 25852190 10531446 1996324 19029954 8503013 16093354 19541618 23153539 16293107 1708096 19933846 26721396 11136732 10205168 20802526 31980649 7760835 18775988 8307946 12917261 11134016 20080631 8180183 1990291
KSR1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 7477354 12932319 9665134 9094715 19766101 23331499 8601312 19595761 11478855 8332195 15520859 8503013 16093354 19541618 19933846 10205168 7760835 18775988 18789263 11134016 8180183 1990291
YWHAZ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
HRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 147.0 1.0 Omnipath 17145710 18273062 9523700 1639773 8601312 19595761 20133694 11032808 9154803 10882715 14654780 1996324 19222999 16301319 11948414 8530446 7969158 11313862 9150145 20080631 1990291 12750173 15031288 12932319 9665134 8805624 8340422 1386920 23331499 16916524 16041367 23180781 18988627 20178605 15688026 15664191 22169110 11733498 7862125 8180183 19063885 12391160 9144171 8035810 9020159 14724584 19696784 21779497 9261098 12173045 12620389 8628317 19914712 1708096 19933846 26721396 7730360 10205168 8332187 16803888 18775988 12917261 9099670 10545207 25684575 8670882 10783161 12379659 10887184 17569879 21071413 8332195 7523381 10531446 24929361 8503013 16093354 19541618 10369681 8911690 18073111 11136732 10922060 7760835 11134016
PRKAA1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 19651622 12801936 19007248 11971957 20166139 20068231 9091312 10576742 9710607 11997508
YWHAH RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12801936 11697890 8702721 17979178
YWHAQ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
NRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 9867809 12750173 12932319 9001246 9665134 8805624 1386920 1639773 8340422 8601312 19595761 23331499 21071413 8332195 10531446 10882715 7811320 1996324 18988627 21779497 8636091 8503013 7766599 16093354 19541618 8180183 1708096 19933846 32296183 9525741 8876196 11136732 10205168 21478863 7760835 18775988 12917261 11134016 18641128 20080631 9488663 1990291
RAF1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17353931 11697890 8702721 10433554 16189514 15664191
RAF1 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 8085158 12620389 16093354 19595761 7882972 16041367 24255178 11697890 7935795 8702721 10848612 16189514 25852190 7644510 12360521 10620507
RAF1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 7565670 12750173 18799465 16364241 11909642 19219045 21988832 23331499 15342917 8933152 9671314 8393135 9808624 8223433 16189514 18988627 18669648 19541618 16293107 10969079 10567369 8157000 11136732 11948414 7898932 9069260 18039929 19369195 8607979 10327068 17116858 24746704 12920017 16129686 19058874 15466214
RAF1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
RAF1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 14688280 7760835 17353931 16041367 11697890
RAF1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 143.0 1.0 Omnipath 10757792 18337766 18799465 15342917 23728975 26496610 15866172 17053865 11242034 9351825 9677429 8157000 7992057 11948414 11604401 16129686 10677502 12695496 19197339 7565670 12750173 7936666 1326789 19219045 23331499 18556463 10976102 18988627 15485920 15175348 18691976 16407412 10409742 9311917 17192257 7898932 8621729 23934108 11684694 21336309 7624324 12920017 11948406 15466214 11042690 12907640 9032297 27169363 12876277 8933152 8223433 8248196 8131746 12594221 10969079 10567369 17979178 17724343 24746704 19058874 10958680 8090753 21071413 7731720 7873542 1330321 8503013 16093354 19541618 8394352 15466476 25155755 11136732 9069260 94178255 8607979 10327068 10359597 8039496 20212043
RAF1 YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19608861 16093354 16041367 11697890 8702721 16189514 25852190 7644510 15459208 17979178
HRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
HRAS YWHAB â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
HRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS MARK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
HRAS YWHAB â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
HRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 7706312 14970219 18567582 12932319 8073291 1386920 23331499 8601312 9154803 18988627 8668348 21779497 19541618 19933846 17563371 18098337 16803888 26165597 24441586 16135787 12917261 15710605 10545207
KRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
NRAS KSR1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
KSR1 BRAF â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
KSR1 BRAF â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
FOS KSR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
BRAP KSR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18796711 23105109 14724641 18332145
KSR1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8503013 19541618 15090600 11741534 1330321 17613518 11940661 18332145 7992057 8248196 15520859
KSR1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 17145710 19541618 27086506 17613518 11909642
KSR1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19541618 8601312 19933846 12932319 17613518 18332145 15710605
KRAS YWHAB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12068308 23352452 25907612 15035987
NRAS YWHAB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12068308 23352452 25907612 15035987
PRKCZ YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16189514 10620507 21900206
IKBKB YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16024783
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
BRAF YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 12620389 17353931 24255178 15324660 10931830
YWHAB YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17085597 12657644 12426317 15071501
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
KRAS PRKCQ â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 Reactome 23943869 26590425 9436858 11585916 29311131 20802526 25713064 16483930 24033119 27697864
PRKCQ IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17363905 11120819
KRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
KRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
NRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
PRKCZ MARK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15084291 15324659
PRKCZ IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10195894 9689078 10779355 11460167 10022904 10356400
PRKCZ EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PRKCZ MARK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15084291 21983960 15174125 24719451 23312004
PPM1B IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 14585847 18930133
MARK3 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 27038604 15150265 10744722 9836640 9543386 12941695 20068231 17097061 9278512 10681541 15791647 11551930 9278511 11333986 15629715 10557092
BRAF YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 17353931 15324660
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAG YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17085597 21827211 12426317 15324660 15071501 12657644
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
PRKAA1 HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27010499 18184930 21892142
KRAS MARK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
BRAF MARK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
NRAS MARK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
MARK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MARK3 MAP2K1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
PIM1 MARK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15319445 26186194
CAPRIN1 G3BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17210633 34799561 18005740
KRAS MAP2K1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
NRAS MAP2K1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
BRAF MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 20212043 7706312 25437913 9560161 7936666 14970219 18567582 18332145 8413257 23331499 15342917 21071413 7731720 7873542 26496610 10976102 18988627 17667937 16255777 8131746 16888650 15485920 8394352 15175348 15466476 19541618 25600339 25155755 17563371 16810323 8157000 17979178 18039929 94178255 23934108 7835430 7624324 24746704 16135787 7935374 8039496 8621729
KRAS BRAF â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 24937142 16294014 12932339 7744815 9020159 15035987 16364920 11325826 16041367 24347342 12932319 10205168 21441910 23993095
YWHAH BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8085158 8085159 10931830 7744815 8668348
KRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 1386920 23331499 19541618 8601312 14970219 18567582 16135787 12932319 17563371 12917261 19933846 21779497 17635919 19223544 15710605 8073291
NRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 1386920 21478863 9368069 19541618 8601312 14970219 18567582 16135787 7935411 12932319 12917261 17563371 19933846 21779497 8073291 15710605
BRAF YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16713569 8668348 17353931 15324660
BRAF YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 17353931 8668348 15324660 15161933
BRAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 15342917 18039929 19541618 7706312 15466476 25600339 7731720 16135787 17563371 33226073 8668348 17667937 16255777
KRAS MAP2K2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
YWHAH YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501
KRAS BRAP â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19091743 14724641 18332145 23105109
NRAS BRAP â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19091743 14724641 18332145 23105109
RASGRF1 NRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1379346 9032266 11560935 9379834 9430727 7828890
YWHAZ YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21827211 12657644 12426317 15071501