Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SKP2 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16376880 5218183
FGFR3 CDKN1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CDKN1A UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKT1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
EGR1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12690110
CHGB OGG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB POLD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB PTEN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PTEN CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12297295 11035045
MAST2 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15951562
EGR1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12384981
PTEN SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12804776
LRRK2 CHGB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
MARK3 PRKCQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219779 17363905
SP1 EGR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20121949 7384875
SP1 PRNP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19064990
EGR1 CHGB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16987240 21257751
SLC25A6 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FGFR3 POLR2E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TFAP2A PRKCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12269829
MFHAS1 CHGB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
CHGB SLC25A6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB TAFAZZIN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB CBFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB CCDC92 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB TUBB2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB POLR2E â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB TWF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB ACACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB SAFB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB MGLL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB MOGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB UBTF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB RXRG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB S100A8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB ATXN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB PRAG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CHGB YLPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
REST CHGB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19118055
RAP1B PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11476890 16919435
POLR2E UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PTEN PTK2 â—¼   DEPHOSPHORYLATION ✅ - 0.81 0.81 Signor 10400703
SKP2 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19270695 21358672 23911321 19270694
LRRK1 LRRK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19712061 20144646
LRRK2 MOGS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
SYT1 SYT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT1 CDKN1A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 31575057
AKT1 STK11 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 24412244 28205554
AKT1 SKP2 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
EGR1 SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20121949 12569082
PKN2 AKT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10926925
CHGB STX1B â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
CHGB SYT2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
AKT1 PTEN â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
AKT1 SMAD2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16362038 24412244
AKT1 PTEN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12297295 19903340 12077256 28628118 20605778 28205554 10866658 20596030
PTEN MAST2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15951562 22894835
PTEN PTK2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMAD2 SP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11114293 10878024 22227581
CDKN1A SKP2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CDKN1A S100A8 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDKN1A CHGB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CREB1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25379405 14520699 21295542
SP1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22412893 23995788
SMAD2 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9689110
PTEN CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21385900
SP1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
FOS POLR2E â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FOS CHGB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20359597
ANXA7 CHGB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RCC1 CHGB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CHGB PKN2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CHGB RAC2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CHGB TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CHGB RAP1B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SYT1 STX1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9010211 11438523
S100A8 RAC2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23980663 22808130 21239714
MAST2 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 TUBB2A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
STX1A SYT1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 11438523 9010211 10397765
MAST2 PTEN â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CHGB STX1A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CHGB SYT1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
STX1A SYT1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
TFAP2A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21084835 9473523 16867219 16288208 11420667 18955504 20805990 8988173 17875680 12226108
FOS CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12705898 12087103 14755691 16141357 10891399 11789587 21864583
SMAD2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9618481 12200968 17516505 14762439 10506225 24052079 14583455
EGR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18316600 20368687 19508870 24384380 17307334 11502738 12690110 21642427
SP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 9580699 15978937 15557281 11064455 16103879 19584258 20301197 20935676 15961274 15361832 11274368 11842244 15489892 15302882 10212208 12796485 23184467 14529564 12806965 9819384 10321829 10649433 12434298 18270969 18850004 16081043 9183012 21858218 10809237 9618481 16298343 11574165 10362258 11384995 15659839 14744793 10030670 17090534 10733944 19318349 12665570 18202149 17516505 15033443 22001409 17885207 10485470 9553133 15345676 15694838 22427654 17556661 10506225 23066038 15979845 18636159 14527674 24821727 15899840 14755691 12151347 24589735 18210215 23877711 11953011 21311948 15528212 15790310 10878024 22132221 12782287 12773551 8995437 21184768 12379120 17026958 24451377 10601254 8557703 16810128 16533812 7499379 10625687 15389873 16706751 12727210 21325288 16818630 18419600 15041706 23235480 19244234 15694666 23329847 18509005
SKP2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 32035614 25241761 23261596 17679094 15998794 17477906 19686743 16376880 15980415 18794347 13678583
SMAD2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9389648 9618481 12545156 17550342 11013220 15155580 9670020 11074002 11283614
AKT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11756412 11923280 16697215 20452955 27603133 20398329 18372248 15001356 15808505 10217147 19440234 20138985 12431783 10753973 17855660 19216069 28358423 20214616 11463845 9829964 17570479 17646672 16680151 11231573 15169778 12851486 31575057 25241761 23109003 21933447 10949026 16775416 23886938 26436589 16288292 11715018 16055744 18636226 15023346 9812896 12042314 17680028 24848107 16982699 11779850 10722653 20832730 18570873 20307683 34069970 17052453 15798220
SP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17026958 9389648 9618481 17550342 12545156 11013220 15155580 11074002
PRKCA CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17855660 10753973 11756412 15851482 16055744 15001356
STK11 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 25763354 17875968 15987703 16107342 11035045 12077256 18321849 23379765 21779440 12297295 25336918
STK11 MARK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19369195 12879020 17192257 14976552
SMAD2 SP1 â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
SMAD2 SP1 â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020
SMAD2 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19558215 10878024 12631740 11013220 11114293
PTEN AKT1 â—¼   DOWN_REGULATES ✅ - 22.0 1.0 ACSN 10753747 11747822 12040186 15721744 16288286 16982858 17218262 17409395 19440036 19847259 19945467 20609352 21084277 22179046 22465479 23732914 24030100 24254977 25364523 26597054 27328425 27572739
EGR1 PTEN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17330857 17479230 20514024 12917634 17516844 15231710 18062928 18324520 11781575 20862322 16138117 21297666 20959484 16424010 15517593
AKT1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 19903340 15987703 10790335 20596030 10592173 20605778 10866658 12077256 11035045 16107342 12297295
CSNK2A1 PTEN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 16107342 33760042 18723495 25823029 21840932 10866658 24766807 16690621 21779440 24706748 19662498 28263967 15987703 11035045 12077256 24047694 11707428 22413754 17444818 26832662 12297295
PTEN PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9616126 15717329 10427092 23109003 10400703 10592173 9927060 23397142 11857088
SP1 SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16969077 16883603 19329185
AKT1 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23807222 28446188 22733130 19270695 20160512 19549334 21963805
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
SP1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20427719 18044710 9282327 8349585 10826704 10082539 12637574
SP1 BTK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11254710 11779634 7721790 10362515 8562928
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
SP1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17626239 10082538 9528985
SP1 ACACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9240931 8576128 9271397 8663083
CSNK2A1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9153193
CSNK2A1 EGR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8662759
CSNK2A1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 29732088 17374729 21506126 11689703 10671551 12149249 15818404 10747897 10837139 20976471 19662498 21285348 11035045 11707428 21735093 17444818 20558317 11972058 16707567
AKT1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11175347 11756412 12356771 15733869 20452955 20398329 11160957 10217147 19216069 20214616 11463845 9829964 7958915 12235136 16680151 17646672 9687510 8887554 11698596 8688081 17680028 9528766 11018520 11969286 12519783 11909979 15725726
PTK2B PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9182576 16254240 15247219 16760434 7529876 12960434
CSNK2A1 STX1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15822905 10844023 9930733 19748891 11846792 25774383 18510355
CSNK2A1 TFAP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21777522
S100A8 BTK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 21873236 11544529 22454496 16439361 15944945 12724322 17726518