LRRK1
|
ABL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8010101
20697350
|
ABL1
|
SOS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
MAP4K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
DAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
ABL1
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
RIMS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
ABL1
|
PLK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
27899378
|
GRB2
|
ACTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
LRRK2
|
BAG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
CCT5
|
BAG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SQSTM1
|
BAG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7263374
19229298
|
BAG3
|
SQSTM1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7263374
19229298
|
PPP5C
|
CCT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8204010
21360678
|
CCT8
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SCEL
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PPP5C
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8204010
21360678
|
CDC37
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
21900206
2001699
8089645
|
GRB2
|
DBN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
HSP90AA1
|
DNAJA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8204010
21360678
|
HSP90AB1
|
DNAJA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
22011577
21700222
|
SPTAN1
|
FKBP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
GRB2
|
RIMS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
SPTAN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
TUBB4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
GAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5212828
10913131
|
GRB2
|
DOK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731746
16436051
|
GRB2
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
TUBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
SPTBN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
CBLB
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
GRB2
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17993263
15031289
|
DOK3
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17290227
32323266
|
HSP90AA1
|
DAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16551624
|
CD2BP2
|
NEDD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16000308
5217817
|
PPP5C
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8204010
21360678
|
SQSTM1
|
TUBB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DAPK1
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
SOS1
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
9544989
6547749
|
SHC1
|
GAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10704825
5212298
|
SCEL
|
DAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
DAPK1
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
DAPK1
|
TUBB4B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
DAPK1
|
CDC42EP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
DAPK1
|
VGLL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
DAPK1
|
SNX9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
DAPK1
|
POLR2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
DAPK1
|
PAK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
SCEL
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
LRRK2
|
VGLL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
LRRK2
|
CHGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
LRRK2
|
CDC42EP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
LRRK2
|
CBLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
LRRK2
|
POLR2M
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
CBLB
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
CBLB
|
FGFR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
CHGB
|
S100A8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
LRRK1
|
BCR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8010101
20697350
|
DOK3
|
INPP5D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219623
17290227
|
GRB2
|
MAP4K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
HSP90AB1
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
LRRK2
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
GRB2
|
RET
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
CDC37
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17525741
25036637
|
PTPN11
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
16729043
5218694
|
LRRK1
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19712061
20144646
|
TCF25
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24947832
|
SOS1
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
8112292
7529874
|
SUGT1
|
RSU1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25036637
|
LRRK1
|
HSP7C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24510904
24947832
|
ABL1
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
SHC1
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
8112292
19380743
10194451
|
CDC37
|
FKBP5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
25036637
24981860
|
PPP5C
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
27880917
|
STUB1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
16293251
5218068
|
LRRK1
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24947832
31980649
20697350
|
SHC1
|
SOS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10675333
19380743
|
SHC1
|
HSP7C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
31980649
19380743
24189400
|
LRRK2
|
HSP7C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
18367605
24947832
23455607
19826009
29519959
31046837
28320779
24510904
17400507
|
GAB2
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ABL1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
CBLB
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9614102
16189514
|
HSP90AB1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
RET
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
LRRK1
|
ABL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
29513927
24947832
20697350
|
LRRK1
|
PLK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
26192437
29513927
|
LRRK2
|
PAK6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
24510904
24947832
26375402
|
PAK4
|
PAK6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
32707033
33961781
26186194
|
FKBP5
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
PTPN11
|
EGFR
|
â—¼ DEPHOSPHORYLATION
|
✅
|
-
|
0.86
|
0.86
|
Signor
|
12582165
|
DAPK1
|
BAG2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
29513927
25852190
|
LRRK2
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18367605
22612223
20642453
26355680
16321986
23075850
|
NEDD4
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19953087
33762435
29455656
|
EGFR
|
SNX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
GRB2
|
INPP5D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
GRB2
|
LRRK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31980649
24947832
19380743
20697350
|
PPP5C
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
27880917
|
CDC37
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
LRRK1
|
BAG5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24510904
24947832
29513927
|
BAG5
|
HSP7C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
27684187
24510904
29568061
32850835
|
LRRK1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24947832
28065597
29513927
|
HSP7C
|
GAK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
16189514
10625686
33961781
24510904
29568061
|
DOK3
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19380743
16436051
|
GRB2
|
HSP7C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19380743
31980649
12577067
33957083
|
BCR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
DNAJA1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
BAG1
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
ABL1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
ACTN4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
26320552
|
LRRK2
|
BAG5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24510904
24947832
19001729
|
EGFR
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25036637
31980649
12471035
24189400
23956138
|
VAPA
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20029029
31980649
25754235
23956138
|
CBLB
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24797263
11375397
20308550
19531499
33848699
10635327
30515972
18271526
28572092
10086340
16729043
31959764
16702950
15657067
|
EGFR
|
RET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24658140
25402006
31980649
28460442
|
GAK
|
LRRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24510904
24947832
26375402
29513927
|
RET
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16189514
32062451
9393871
8183561
7665556
10995764
15677445
|
FGFR2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24440983
22726438
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
GAB2
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12135708
14982882
10704825
11782427
|
HSPA8
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
EGFR
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
PTPN11
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
FGFR2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
ABL1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23950177
16713569
17474147
14725908
9407116
9516488
8194526
19380743
19823681
7926767
16955467
|
ABL1
|
BCR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12543778
1712671
8112292
21653319
11780146
|
ABL1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
24658140
16273093
25402006
7678409
|
EGFR
|
CDK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
23956138
24658140
25402006
18271526
15657067
|
SOS2
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24797263
31980649
23956138
19531499
24658140
25402006
18271526
31959764
10675333
|
EGFR
|
HSP7C
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20029029
31980649
12471035
24189400
23956138
24658140
28065597
25402006
15657067
|
GRB2
|
ASAP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
31980649
21988832
17474147
21706016
33961781
20936779
19380743
|
PLK1
|
SUGT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21864708
22869522
|
SHC1
|
RET
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
32062451
8183561
28213521
15677445
9047384
|
INPPL1
|
INPP5D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
9108392
9099679
10570274
|
SNX9
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
0509166103
7102318
16636290
|
EGFR
|
SOS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
EGFR
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
GRB2
|
SOS1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
23452850
|
GAB2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
907.0
|
0.9
|
STRING
|
36370105
|
INPP5D
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
FLT4
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
SHC1
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
FKBP5
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
HSP90AA1
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
BAG3
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
GRB2
|
BCR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
5214841
11726515
|
HSP90AA1
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
HSP90AB1
|
PPP5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHOSPHORYLATION
|
|
|
0.92
|
0.92
|
Signor
|
11726515
|
SOS2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
5220477
7629138
|
HSP90AA1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
EGFR
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
HSPA8
|
STUB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
GRB2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
BAG2
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
955.0
|
0.95
|
STRING
|
36370105
|
CBLB
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
SOS1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
24797263
16713569
26005835
9447973
23956138
19531499
7510700
20473329
19289468
25754235
18271526
31959764
10675333
8621459
|
CBLB
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
959.0
|
0.96
|
STRING
|
36370105
|
SHC1
|
SOS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
8631299
10570290
10025673
8235613
8626525
9544989
10675333
10783152
8950973
7559490
19380743
16371368
9344843
7520523
8621459
|
HSP90AA1
|
PPP5C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
965.0
|
0.96
|
STRING
|
36370105
|
HSP90AB1
|
SUGT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
HSP7C
|
BAG2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
25036637
18457437
22365833
9873016
33961781
30021884
27684187
26344197
29568061
16207813
|
HSP7C
|
BAG3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
25416956
23824909
25036637
30559338
9873016
26496610
33961781
21233200
27684187
21423662
29568061
|
SHC1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7518560
8034616
31980649
23956138
9544989
8610109
7542744
25402006
16729043
8665853
15657067
9742218
24797263
10049786
12577067
9756944
23799367
25187647
20935677
10766863
18271526
11408594
7506413
10635327
10595738
24189400
19531499
7542991
20473329
24430869
8662998
9020193
8887653
16273093
25754235
9388490
31959764
26551075
16713569
22973453
24658140
11196191
28065597
20067773
8810340
21278788
30544639
9130710
11370743
|
EGFR
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
19254954
7518560
31980649
9416834
7592693
23956138
14679214
10085134
7510700
27059931
21706016
25402006
16799092
16729043
8665853
15657067
24797263
12577067
8810325
7650032
11960376
23799367
25187647
8626525
10026169
19289468
18271526
21278786
7506413
17971399
8940013
20124286
11726515
9886492
10595738
24189400
9020117
19531499
20473329
9020193
8662998
8647858
1322798
8887653
10229072
16273093
25754235
31959764
11370743
16713569
21596750
9685397
24658140
31985874
22973453
11896612
20067773
17242169
19836242
8810340
21278788
30544639
7527043
9050991
11408594
8621459
|
SHC1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
8940013
6169950
|
SOS1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
5220480
7642581
|
BCR
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
8112292
11726515
15143164
9747873
10887132
8995379
8955135
9174058
14725908
21706016
33961781
19380743
32203420
9178913
7529874
|
GAB2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
25416956
31980649
21706016
10068651
16371368
10391903
32296183
15143164
10913131
19523899
19172738
11782427
19380743
11882361
9660791
16253990
33961781
20936779
|
HSP7C
|
BAG1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
17954934
16189514
25416956
28215707
9774640
20675402
14978028
9873016
12874020
10671488
11222862
19800331
25535373
26871637
9305631
11707401
11741305
12297498
|
SPTAN1
|
SPTBN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
GRB2
|
SOS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
GAB2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
SHC1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16729043
5218694
|
GRB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16729043
5218694
|
SHC1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
12485888
21725358
31980649
9126968
7514169
7744881
8235613
11453982
8662733
8491186
7629070
8940013
10570290
8112292
12213123
11302736
8662998
8195171
7597091
8810340
32062451
9129019
16371368
12149229
10049786
8626525
7650032
8950973
9488479
24189400
15812354
12441060
19380743
26551075
22057045
10477741
28690151
16713569
7516467
9733714
11827484
11964172
7537740
16520382
9019162
8663178
9797459
9032244
12577067
9927207
7524086
8995379
9886492
8294403
7559490
9434624
11792427
7798267
8621719
9541596
15688026
12898421
33961781
11370743
25416956
9544989
22974441
8939605
21706016
9083103
7535773
11505033
9175774
24430869
10080542
9020193
9045692
10356320
15888547
9254595
8561895
11707405
8647288
|
SOS2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
31980649
32062451
21988832
17474147
14679214
21706016
7629138
33961781
20936779
10940929
19380743
32203420
|
CBLB
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
21900206
28514442
16189514
25416956
31980649
12577067
31467278
26264872
10022120
9614102
29997244
21706016
32814053
33961781
20936779
10086340
27107012
|
BAG1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
HSP90AA1
|
SUGT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT6A
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT6A
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT6A
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CDC37
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CDC37
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT7
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT8
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT3
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT5
|
CCT7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCT7
|
TCP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
GRB2
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDK1
|
ABL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
19651622
17081983
2183353
18691976
18452278
18669648
|
ABL1
|
BCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
9407116
10405761
12522270
11780146
8622703
9178913
1712671
12124177
7529874
9467953
8955135
20841568
8112292
16912036
12543778
11376433
|
ABL1
|
MAP4K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11278340
17474147
9346925
|
ABL1
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15039778
20841568
8112292
|
ABL1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
11726515
16713569
20841568
8596638
16955467
10592173
8647802
8194526
7926767
14725908
23950177
8112292
9407116
23181695
19380743
17474147
9516488
19823681
|
ABL1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
24430869
15192046
33889303
16273093
16943190
14760089
29880877
15618223
33574089
8910327
12631709
25173817
25402006
20841568
33947961
34107301
34469737
19915609
32019812
2022651
34290403
33707748
15329413
7678409
9733788
8490966
28338646
3263271
15901825
2022652
10069801
7506413
24658140
8408058
34385595
31980649
1314835
7741752
18668345
28724430
12648464
25073158
26079946
34155348
|
ABL1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
8617726
1623525
10194451
19380743
10592173
20841568
8112292
|
BAG2
|
STUB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16169850
16207813
25036637
|
BAG3
|
HSPA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
25036637
27474740
23824909
21233200
9873016
26496610
16189514
21423662
|
SHC1
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
16187797
15284455
17646646
16969069
17372273
17712310
|
PPP5C
|
CDC37
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
21360678
18922470
|
CDK1
|
PLK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17596790
17660363
18414028
18543256
18590585
18995830
19652693
19686080
7575488
9892021
|
CDK1
|
CKAP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19641375
19369249
|
CDK1
|
PLK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17764786
17660363
15279786
15917306
|
CDK1
|
SQSTM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
26279575
22424619
23856904
20974803
29423120
17570479
28963527
|
CDK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17145710
31980649
8360196
23956138
15901825
28150246
18271526
15657067
24658140
25402006
15302935
|
HSPA8
|
DNAJA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20084477
20809635
24012426
7828728
20072699
|
EGFR
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
EGFR
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
CBLB
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17145710
19531499
11375397
10086340
12577067
10542134
17635922
10514377
|
PTPN11
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
28065597
9756944
7588774
16273093
14560030
9642214
8197172
15618223
12270932
7673163
12582165
10411909
16729043
11223155
12577067
|
SNX9
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
16316319
24658140
25402006
|
EGFR
|
SOS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
23956138
19531499
18271526
24658140
10675333
25402006
24797263
|
EGFR
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
109.0
|
1.0
|
Omnipath
|
9544989
10595738
23956138
27059931
10026169
16273093
11726515
24697349
21596750
19289468
7518560
21706016
23799367
9050991
16317285
16713569
25402006
11370743
24797263
8647858
8887653
9416834
21278786
16799092
8662998
10229072
11896612
7592693
19509291
8810325
24189400
19836242
11960376
7506413
18271526
15657067
10085134
24658140
17242169
7510700
8940013
7650032
8810340
11084343
12577067
7527043
31980649
11408594
19531499
20124286
23178716
9886492
23181695
9020117
8479540
14679214
12648464
1322798
17991782
16729043
17971399
|
EGFR
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
78.0
|
1.0
|
Omnipath
|
9544989
8808684
10595738
23956138
9388490
11350724
16273093
7542991
7681824
7518560
9710588
23799367
16713569
25402006
11370743
24797263
9742218
20935677
8887653
8034616
23331499
8662998
7542744
10049786
28065597
9130710
10635327
24189400
7506413
18271526
15657067
24658140
8810340
12577067
11196191
10766863
23178716
31980649
35384245
11408594
19531499
9756944
26551075
1623525
15951569
16729043
17956904
|
EGFR
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
9544989
19531499
9447973
16713569
12577067
|
EGFR
|
LRRK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
24947832
22337768
|
GRB2
|
FLT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11283723
11335727
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
15863030
16000375
16002046
16076871
16102570
16212621
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19223473
19414323
19449109
19454690
19909365
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24027568
24217602
24346288
24670066
25922287
26201938
26552706
7510700
8551221
8837607
9157999
9570538
9753319
9763606
|
SOS1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
28514442
16520382
31980649
32062451
8493579
21988832
14679214
7510700
7514169
21706016
10319320
32203420
9872323
9797459
34407391
16906159
10716926
12577067
8810325
7629168
11960376
7664271
8626525
15192046
7629138
11997436
8943292
10207103
8695800
10570290
10025673
8112292
11726515
8816480
20473329
7559490
7773779
9447984
19380743
7642581
7527391
9716598
9344843
10477741
16713569
19323566
7516467
17474147
9569023
8188688
16893902
11964172
9478994
33961781
8479541
28166272
9009162
|
GRB2
|
SHC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11283723
11335727
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
15863030
16000375
16002046
16076871
16102570
16212621
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19223473
19414323
19449109
19454690
19909365
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24027568
24217602
24346288
24670066
25922287
26201938
26552706
7510700
8551221
8837607
9157999
9570538
9753319
9763606
|
GRB2
|
FLT4
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
PTPN11
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10358138
11447289
11572860
12138178
12707331
15240681
15699106
15713798
19833085
9751747
|
GRB2
|
FLT4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
GAB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10086337
10358164
10567412
10811803
10849428
10982827
11447289
11449354
11777939
12175651
12393695
12640133
15567848
15574420
16076871
16212621
16582911
16887996
17496910
17673906
19449109
19909365
26552706
8551221
9763606
|
GRB2
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
69.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11283723
11335727
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
15863030
16000375
16002046
16076871
16102570
16212621
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19223473
19414323
19449109
19454690
19909365
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24027568
24217602
24346288
24670066
25922287
26201938
26552706
7510700
8551221
8837607
9157999
9570538
9753319
9763606
|
SHC1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
198.0
|
1.0
|
Omnipath
|
8808684
9083103
8551221
9126968
8621483
25416956
9252386
8524223
7535773
8662998
11302736
11827484
8995379
9541596
9175774
10207047
7717978
17673906
7744881
11505033
10523831
24189400
9927207
7650032
8810340
9045692
23178716
19531499
15812354
9129019
10356320
12485888
9461587
8114695
7514169
9566877
8939605
16371368
15341520
7529871
10891441
10749687
7524086
26645482
8491186
10592173
10049786
9171350
11707404
7537740
15688026
8663178
19380743
11782427
9544989
16436051
9434624
16713569
21725358
11964172
17314098
11792427
8195171
1465135
12213123
8647288
12955078
10477741
11707405
12577067
9199344
10080542
8112292
7760801
10570290
11997181
7798267
16520382
10961885
8950973
21706016
9448048
8662733
11370743
8051109
9733714
8621475
9254595
8294403
10748054
8621719
8940013
12441060
22057045
7505797
24737791
20697350
9886492
18174162
18273058
8235613
7963520
7523859
|
FLT4
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9927207
8662748
7675451
7970715
|
FGFR2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22726438
19735729
26103942
20554525
23420874
|
RET
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9393871
16189514
15677445
|
CBLB
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
31.0
|
1.0
|
Omnipath
|
10022120
25416956
21706016
31467278
32814053
9614102
17635922
11375397
8626404
16189514
21900206
20936779
27107012
12577067
10514377
19531499
10086340
29997244
|
PTPN11
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
8702859
9361008
16371368
21706016
8041791
11085989
8978300
11432792
15882975
9362449
10212213
11684012
7523381
10592173
16189514
10747947
10973965
9632781
8959326
11602579
12577067
9254654
10080542
15010462
31585087
12531430
8995399
19380743
7522233
9804835
7534299
9824671
9660791
|
GRB2
|
INPP5D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
10660611
32323266
15456754
10748054
17043143
9108392
10900203
10068665
10891441
22267732
8723348
|
GRB2
|
GAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
17145710
16371368
25416956
21706016
15143164
10391903
19172738
10913131
11027663
9973481
10973965
20936779
10068651
11882361
32296183
16199887
24737791
15010462
19523899
16253990
19380743
31515488
11782427
|
GRB2
|
MAP4K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9346925
9891069
9788432
17474147
11279207
|
GRB2
|
SOS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17145710
21988832
20936779
19531499
14764585
10940929
19380743
21706016
10359574
14679214
17474147
21779497
9199344
7629138
|
GRB2
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
145.0
|
1.0
|
Omnipath
|
9544989
9872323
7642581
15746962
11726515
8621483
23334917
16520382
11997436
21706016
10359574
8950973
7664271
16713569
16893902
16906159
21988832
19323566
9009162
10716926
11964172
7629168
9815779
10592173
9716598
8647802
28166272
7773778
7773779
18778683
8188688
10319320
8810325
9344843
23452850
11960376
8816480
10025673
7510700
8940013
12955078
9697839
12345678
10477741
8493579
8943292
12577067
7862167
9199344
8112292
7898932
10207103
8695800
19531499
10570290
7760801
20005866
19380743
9447984
8235613
8479540
7527391
14679214
8479541
17474147
7514169
7629138
|
HSP90AA1
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
16187797
15284455
17646646
16969069
17372273
17712310
|
HSP90AA1
|
PPP5C
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10400612
16531226
21360678
15577939
15383005
|
PTPN11
|
GAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
10358138
10849428
10982827
11447289
11572860
12138178
12640133
12707331
15240681
15699106
15713798
16212621
19833085
19909365
9751747
|
PTPN11
|
GAB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
10358138
10849428
10982827
11447289
11572860
12138178
12640133
12707331
15240681
15699106
15713798
16212621
19833085
19909365
9751747
|
PTPN11
|
GAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
17145710
11287610
15356145
12135708
10391903
19172738
23331499
14982882
11334882
11027663
21636860
10973965
19909739
11812650
10068651
11572860
15170389
9885561
15010462
18950707
16253990
18725415
10871282
11782427
|
PTPN11
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12577067
9632781
9344843
|
SHC1
|
FLT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
SHC1
|
FLT4
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
SHC1
|
GAB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
25.0
|
1.0
|
ACSN
|
10086337
10358164
10567412
10811803
10849428
10982827
11447289
11449354
11777939
12175651
12393695
12640133
15567848
15574420
16076871
16212621
16582911
16887996
17496910
17673906
19449109
19909365
26552706
8551221
9763606
|
SHC1
|
FLT4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
RET
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
9393871
23331499
9047384
15677445
16189514
9047383
8183561
|
CBLB
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19531499
11375397
16189514
9614102
12577067
|
GAB2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
8995358
10704825
|
FLT4
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
9388490
7675451
9096689
15592455
9121430
9446569
10891441
11687594
23331499
10921922
10482988
10764799
12522270
9685404
10896916
9927207
8662748
8702728
12237775
8610109
9741627
9710204
10816433
11075717
|
SHC1
|
SOS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
9544989
8631299
8621483
8950973
10891441
10783152
9278309
17673906
9344843
8294403
8021500
10025673
7520523
12955078
12577067
9199344
19531499
7760801
10570290
19380743
8235613
10675333
8114695
|
SHC1
|
INPP5D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
9110989
9099679
10570274
9973396
10891441
23331499
9083021
15470047
8643691
10207047
10704825
12024011
10748054
10068665
20697350
10194451
10900203
10856136
10822173
8723348
8874179
|
S100A8
|
TIRAP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
21873236
11544529
22454496
16439361
15944945
12724322
17726518
|
FGFR2
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
11353842
8780727
11447289
7559490
9182757
|
BAG1
|
HSPA8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
25535373
26871637
9305631
11222862
10671488
14978028
17954934
20675402
25416956
9873016
19800331
16189514
9774640
12874020
11741305
12297498
27474739
|
SPTBN1
|
SOS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
19345670
23168613
27795560
31066629
17764812
|