Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PRKN ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20418918
PRKN HSPA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20418918
HSPA1A HSPA1B â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HSPA1B MAPKAPK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSF2 HSPA1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18434628 19336471
HSPA5 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STUB1 MAP3K14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NFKBIB MAP3K14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15609310 20097177
ATXN1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
CAMK2A AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCZ AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18650932 7232391
OTUB1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WDR83 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF2 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 HSPA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MFHAS1 BAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LRRK2 BAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
PPIH BAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
WDR83 BAG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
BAG2 WDR77 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
BAG2 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 NFKBIE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 CCAR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
BAG2 KIF13B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
BAG2 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 SLU7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
BAG2 NFKBIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
BAG2 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7834747 8692945
HSP90AA1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18266962
DAPK1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19395874
BCL2 XRCC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18313378
BUB1B HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7299731 19407811
CAMK2A STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRB10 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
CAV1 TRAF2 â—¼   COLOCALIZATION 2.0 0.8 intact 5213300 11112773
HSPA8 CCAR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CCAR2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCAR2 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCAR2 NFKBIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 CCAR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20160719 20074560
DOT1L CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
CTNNB1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTNNB1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24291232 24482235
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CUL3 HSF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19768582
DAPK1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
TP53 DAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24217921 20943371
MAP1B DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18195017
HSP90AA1 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16551624
DAPK1 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15616583
HTT DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMC4 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMD2 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DLST PPEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 DLST â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17916908 21191025
DNAJB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNAJC7 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNAJC7 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MFHAS1 FGFR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
TP53 HLA-A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15501971 12857899
TP53 HPSE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16474844 16901744
HSP90AA1 NFKBIE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 NFKBIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 MOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25036637 22939624
HTT HSPA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA2 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA4 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA4 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA4 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
HSPA5 NFKBIE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TNFRSF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 NFKBIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP5C HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSPA8 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 NFKBIE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TRAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 NFKBIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TTC1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PINK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STUB1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF2 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IRAK1 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 MAP1B â—¼   COLOCALIZATION 2.0 0.8 intact 18656471 6700545
MAP3K1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23109003 15032589
MAP2K2 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18039929
MAP3K3 MAP2K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYLK2 MAP3K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MAP3K1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9008162 10465784
TNFRSF1B MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12517920
STUB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NUDC MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYLK2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PRKCB MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8626698 16189514
RPS6KA3 MAPK7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MFHAS1 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
MYLK2 TNFRSF1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYLK2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A NFKBIB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
OTUB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19996094
PINK1 PARK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 21179058 23725295
RAF1 PPP5C â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16892053 21779496
TP53 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10614633 9895308
PRKCZ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 10620507
PSEN1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19012753 18996842
PSMD2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PSMD6 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF1 RIPK1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 5220954 8612133
STIP1 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TRAF2 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
TRAF2 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RAF1 STUB1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
METTL14 METTL3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HSPA2 HSPA8 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
P53 CHIP â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 27775703 29953728 35140242 22254155 25543083 32097779 30911017 25144556 26330542 18223694 23134341 15911628 20618441 17666403 21268072 27807478 15001357
RAF1 CHIP â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25036637 22350907 15215316 19011619 15936278 34017080
CHIP TRAF6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 23322406 24578159 21911421
OTUB1 TRAF6 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20622874 34591986 19996094
BAG2 HSPA1A â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
DNAJC6 HSPA8 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
LRRK2 STUB1 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
P53 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32807901 22653443
LCK HSP71 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 34079125
SRRM2 HSP71 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16159877 22939629
MP2K2 BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 31980649
KPCZ BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29491746 31980649
BAG2 STXB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
ATX1 BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32814053 25959826
SOCS1 TBG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15456882 29991678
LRRK2 TBG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
ARAF HSP7C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29777862 31980649
HSF2 HSP7C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK1 HSP7C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24510904 24947832
IRAK1 HSP7C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29568061 15647277
DNJC7 NPHP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BAG2 DNJB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 33957083
BAG2 DNJB6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 33957083
PRP8 BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28515276 34079125
PRP8 STIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28515276 34079125
PRP8 CHIP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28515276 34079125
CHIP MLF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
TTC1 BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
ILK BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 23455922
MKS1 BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26638075
BUB1B BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 33961781
STIL BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26638075
NPHP4 BAG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26638075
BAG2 RAF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 31980649
BAG2 TAB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
BMI1 NAT10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
BMI1 NCBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CUL3 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 21145461
RAF1 DCAF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16364241 34017080
LRRK1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20144646 19712061
LRRK2 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
MAP3K3 TRAF6 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
TNFRSF1A TRAF2 â—¼   UP_REGULATES ✅ + 0.82 0.82 Signor 10795740
MLF1 RIPK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
XRCC6 P53 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11751391 15782130 32807901
LRRK2 P53 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24725412 26384650
P53 BAG2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 22653443 27807478 25144556 23443559
P53 DNJC7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23261415 35140242 33961781
BCL2 HSP71 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10354271 16713569
HSP7C MP2K2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 31980649
TRAF6 KPCZ â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10747026 16189514
PRKN2 BAG2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32929329 25959826 24244333
PRKN2 PSMD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23503661 20810900 25959826
ATX1 HSP7C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32814053 17127076 25959826
ILK HSP7C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 23455922 33961781
LRRK2 HSP7C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19826009 23455607 28320779 31046837 24947832 17400507 18367605 24510904 29519959
AKT1 HSP7C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16027165 31980649 24462114
BAG2 DNJC7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 26496610 33957083
CHIP DNJB6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25036637 22366786 33957083
2ABG SIK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24841198
PRP8 SLU7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22365833
ARAF BAG2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25852190 29777862 31980649
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
HSP90AA1 PINK1 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
STUB1 HSPA8 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16293251 5218068
RAF1 LCK â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 8939988 16189514
HSP90AA1 KCNH2 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PSEN1 TRAF6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
TF65 P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17434128 28205554 28628118
HSP7C TTC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10567422 30021884
IRAK1 CHIP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 32707033
JAK3 CHIP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
ILK CHIP â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23455922 32707033
LRRK2 STIP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31046837 24510904
TRAF2 TAB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19150425 17384642 14633987 10882101
BUB1B FZR1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
PARK2 TRAF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
RIPK1 TAB2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
KSR2 MP2K2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27086506 32707033 33961781
ATX1 TRAF2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32814053 25416956 32296183 16713569
RAF1 HSP7C â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16093354 20039095 31980649
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
TAB2 TRAF2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
HSPA4 SGTA â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
M3K14 HSP71 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 31980649
TAB1 HSP71 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
TAB2 HSP71 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
RIPK1 HSP71 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
HSP71 ATX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25959826 16713569
TF65 HSP7C â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 24175631
TF65 BAG2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
DNJB6 HSP7C â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25036637 10954706
M3K14 HSP7C â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 31980649
M3K14 BAG2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 31980649
OFD1 DNJC7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 26638075
DNJC7 CHIP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 33957083
DNJC7 STIP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 33957083
AKT1 CHIP â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21767636 18292230
CHIP TRAF2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 21793045
TAB2 BAG2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
LRRK2 PSMD6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31046837 24725412
TRAF6 PSMD2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
TRAF6 PSMD6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 17353931
CACYBP CTNNB1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
AKT1 PRKCZ â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
BCL2 RAF1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
MLF1 DNJB6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25036637 23414517 26186194
HSP71 TF65 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 14743216 24175631
TAB1 HSP7C â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 14743216
NPHP4 DNJC7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26638075
DNJC7 WDR62 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 33957083
NUDC DNJB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25036637 27173435 33957083
2ABG BAG2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28330616 19156129
SRRM2 PRP8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28515276 26344197 34079125
ARAF RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 34017080 20130576 31980649
DAPK1 BAG2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 29513927
DNAJB1 HSPA4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ILK RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 23455922 26496610
NUDC POC1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 25036637 33961781 26638075
TRAF6 TRAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27107012 32296183 25416956 21988832 21516116 28514442
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
HSP90AA1 HSPA1A â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MED19 MED9 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
SLU7 SRRM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HSPA4 PARK2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA8 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
HSPA4 STIP1 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
P53 OTUB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22124327 24403071 27561390
P53 HSP7C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28215707 31152661 8940078 31027880 11707401 32807901 11297531 8729618 7954368 25144556 23443559
KPCZ RAF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10620507 16189514
TBG1 BAG2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 26496610 23443559
DNJB1 HSP7C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10075921 33957083 11093761 27708256 16189514
HSP7C DNJC7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33957083 10567422 26496610 27684187 29568061 25864199
M3K14 TRAF6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9275204 16189514 16286467 25241761 10921914 11278268
DNJC7 DNJB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26496610 33957083
MLF2 DNJB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25036637 33957083
LRRK2 CHIP â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19536328 31046837 28320779 29513927 24510904 19196961
CHIP BAG2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25036637 24981860 16207813 33987175 16169850
ILK AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11825911 11546794 11313365 18339839 11278835 12149249 14500673 9736715 12176337 11445557 16189514
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
HDAC1 BUB1B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15388328 19407811
TRAF2 CAV1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11805080 32041822 16713569 11112773 16189514
MAP1B LRRK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21159966 24754922
MED9 MED29 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 15175163 24981860 14638676
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
HSPA1A STIP1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TNFRSF1B TRAF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MAP3K14 TRAF2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
IRAK1 TAB2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
BCL2 TP53 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
P53 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14976551 20075864 17827154 19011633 10521394 16697957 10777477 16107876 11099047 32494626 16959611 11313951 12426395 18765668 22266186 19303885 25241761 26539911 20633551
KPCZ TF65 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11684013 21131967 16189514 12881425
PRKN2 HSP7C â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14532270 12150907 32814053 32929329 24244333
M3K14 TRAF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20385093 9275204 23543740 15084608 16713569 11278268
MLF2 BAG2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25036637 17353931
GRB10 RAF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9553107 10585452
TAB2 IRAK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23986494 24735611 18180283 12242293 11518704 19675569
RIPK1 TRAF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 32296183 8612133 19287455 16713569 25416956
CTNNB1 PSEN1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
DNAJC6 HSPA8 â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 24789820
MED19 MED29 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
TAB1 TAB2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
P53 BCL2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21624955 16443602 32064756 21597459 19521340 30683842 12667443 23316052 9194558
PRKN2 HSP71 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32929329 24244333 12150907
STIP1 HSP71 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12161444 26344197 33957083 11413142 23414517 10786835
BAG2 HSP71 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 18457437 9873016 16713569 28042827 30021884
HSP71 CHIP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 10330192 25036637 16275660 12150907 33957083 22939629 26010904 32401531 20618441 28042827 27787517 23904609 23271055
MP2K2 ARAF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11909642 32296183 31980649 25852190 24746704 21988832 32707033 16189514
KPCZ AKT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11723139 10085094 18650932 16189514 18353613 14560023
PINK1 PRKN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23319602 19167501 22724072 24357652 27605430 23670163 25591737 28945249 19966284 20153330 17052189 33730565 20798600 19880420 26162776 26116755 23933751 19358826 27528605 32983119 19229105 29330382 25474007
TF65 SOCS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17183367 21084693 29991678 14690596
TF65 MEN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11526476 14508515 16189514 16713569
HSP7C CHIP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25036637 15198682 15538384 16207813 25258038 27709416 23865999 23990462 21454478 20618441 26264872 27684187 29568061 11146634 21911421 17178836 10330192 27283392 16275660 11557750 29317501 16554822 16293251 15215316 26010904 26232501 27708256 28396517 25684577 18988734 25864199
M3K14 TRAF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20348096 9020361 20385093 9275204 16189514 25416956 31980649 23543740 15084608 20184394 16713569 25246529 11278268
DNJB6 MLF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 23414517 24981860 33957083
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
AXL SOCS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 12470648
BAG2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14978028 12502846 8692945
RAF1 BCL2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15849194 9194558 12488548 8910675 8929532
CTNNB1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17404573 16288908 12782598
TP53 BCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12808109 24189068
BCL3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16306601 15469820
HDAC1 CTBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9650586 16713569
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
PPP2R2D DAPK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 085076 20220139 8204016
ELK1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12928043 12750007
HSP90AA1 FKBPL â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
FLT4 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12601080
MAPK6 HDAC11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
HSPA1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
TP53 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31027880 18431400
SOCS1 JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 27144517 11133764 21508344
LCK JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278738 17570479 16189514
LCK RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7935389 8939988 16189514
MAPK6 TUBA1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCZ MAPK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20538799 11158308
MAPKAPK2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28506461 28920952 28920954
MAPKAPK2 TRAF2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28506461 28920952 28920954
MED29 MED19 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14576168 33961781 15175163 24981860 26344197 24882805 21729782 26186194 28514442 14638676
PRKCB TFEB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23599343
PRKCB PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
PRKCG PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14576165
HSP90AA1 HSPA4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
TRAF6 IRAK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18347055
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
TRAF1 TRAF6 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 8153045 21516116
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HSPA1A STUB1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
HSP7C HSP71 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 22939629 27684187 18457437 9305631 11741305 22863883 25864199
HSP7C SGTA â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 16777091 10567422 21988832 23246001
TAB2 TRAF6 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
TNFRSF1A TRAF2 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ARAF MAP2K2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
STIP1 HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ - 0.92 0.92 Signor 27353360
HSP90AA1 HSPA1B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
HSP90AA1 RAF1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
HSPA8 STUB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
RAF1 MP2K2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 11909642 8157000 31980649 8393135 24746704 16364241 19058874 21988832 9671314 16189514 32707033 9808624
HSP7C STIP1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9774640 26344197 11093761 10567422 22939629 25864199
BAG2 HSPA8 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
MAP2K2 RAF1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
IRAK1 TRAF6 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
PSMD6 PSMD2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 17353931 22939629 22863883 28292943
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
MAP2K5 MAPK7 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
HDAC1 TF65 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21983014 15192014 16483679 20001970 27012186 16291753 17000776 11564889 12419806 17827154 16713569 30670829 11931769 16189514 17962807
HSP7C BAG2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25036637 26344197 22365833 16207813 27684187 18457437 9873016 29568061 30021884
HSP90AA1 STIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MAP2K5 MAP3K3 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NPHP1 NPHP4 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
TRAF1 TRAF2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
HSPA8 STIP1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PSMC4 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PSMD2 PSMD6 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
HSPA4 STUB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TUBG1 TUBGCP3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PARK2 PINK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMC4 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PINK1 PRKN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 93.0 1.0 Omnipath 25216678 27906179 19229105 26162776 25847540 29183391 26116755 33730565 26707701 25474007 25365205 25548534 25595529 29372317 24184327 25611507 22724072 20398440 26471730 28626500 29422536 27453777 24962176 24751536 26631732 22944659 17052189 25375667 25088558 33827825 27554669 24357652 24647965 24671417 29660402 30063295 27528605 23256036 29883688 23933751 23670163 23319602 25505445 25849928 23754282 20418918 19966284 25697646 32983119 30012094 34166935 29809156 24901221 28323427 25284222 29689231 30404819 19358826 19880420 20126261 26254304 20966070 29950828 20798600 29991771 24660806 30290272 25611391 25712550 29899409 28920079 25591737 29475881 29337137
DNAJB6 HSPA1B â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 10954706 1754405 1586970 9920933 15802566 12974469 12853476
HSPA1B DNAJC7 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 10954706 1754405 1586970 9920933 15802566 12974469 12853476
HSPA1B DNAJB1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 10954706 1754405 1586970 9920933 15802566 12974469 12853476
TNFRSF1B MAP3K14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 7639698 25152365 19815541 8702708 7544915
TRAF6 MAP3K14 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
RIPK1 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11116146 15047705
TRAF1 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 11278268 15084608
TRAF2 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 9275204 11278268 23543740 18997792 20385093 25416956 15084608 10755617 16713569 9334169 25246529 20348096 20651737 20184394 9020361
TRAF6 MAP3K14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9275204 11278268 25241761 16286467 10921914 16189514 10075662
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
PRKCZ AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11585925 15884057 14560023 16189514 11748077 18353613 11723139 10085094
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
GRB10 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11809791 15722337
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
AKT1 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 21303971 11882383 17680028 20214616 22094462 20398329 21506126 20028971 12040186 18218901
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 ATXN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15757972 15824120 17540008 34302818 24903464 29212253 33709453 12741986 17570479 21722762 29758256 23719381 20037628 23213356 12757707 24858692 20477910
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
ARAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 21988832 18039929 24746704 16189514 32296183 25852190 21779497 11909642
MAPKAPK2 BAG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19651622 15271996 20068231
BAG2 STUB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16169850 16207813 25036637
CUL3 BCL2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
BCL2 RAF1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
BCL2 TRAF2 â—¼   DOWN_REGULATES ✅ - 8.0 1.0 ACSN 11704864 17446862 22039431 23064052 23377657 23430059 23850759 8929532
TP53 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 17693666 8183578 10037739 16738310 18397889 19521340 18487508 21666495 16294215 21656028 22869582 19714248 10744634 8174112 17592775 11782367 19137013 20428827 18682598 11713302 11313951 20501806 9649502 24814047 15767042 24098340 11193470 10329733 21859835 22266868 10953306 19555669 23638218 14684736 19411072 20530667 24155778 8205530 20840522 9000137 15326476
TP53 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12667443 19555669 8205530 19007744 11313951
HDAC1 BCL3 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10754326 10952726 11875494 12907458 14660645 14668329 15465827 15644117 16878026 17404308 17485448 21234400 22796940 23390297 7594497
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
MEN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
TP53 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564862 20697347 20729811 21691299 19411072 24473123 20064927 18245266 18758483 18372914
FGFR1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17496910 25241761 22558232 11401320 12040186 19568798 14585353
PSEN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 17145710 11168528 16126725 11226248 2195779 11161700 12070348 9738936 10037471 18070361 9632714 10092585 9223106 12297048 16306047 10341227 9852041
RPS6KA3 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16213824 18974095
DAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 15355354 17297916 32266931 26626260 27753536 15254178 27681874 22112863 10734067 11883897 21386980 22815859 20851891 11244509 10733583 15542844 26742101 10673501 12091386 18246126 25584963 15489221 20959462 11258706 10801407 10606744 11707453 17339337 12111733 17977830 25229255 34168813
HSPA1A DNAJB1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 10954706 1754405 1586970 9920933 15802566 12974469 12853476
DNAJB6 HSPA1A â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 10954706 1754405 1586970 9920933 15802566 12974469 12853476
HSPA1A DNAJC7 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 10954706 1754405 1586970 9920933 15802566 12974469 12853476
DNAJC7 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875381 20661446 12853476 15189447
TP53 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22466965 18811981 16557594 24492005
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
HSF2 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8035809 20937767 9738016 1508207 8114740 12813038
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
PRKCG HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26804907 24117238
STIP1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 10642522 21235734 21360678 26804907 11413142 24949977 19875381 10786835 20704274 21170051 26496610 27353360 25036637 19996313 9452498 18285346 24462205 22315411 20159553 22729780 22504172 11877417
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
HSP90AA1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25036637 19011619 16093354 8962087 18266962 8408024 23118896 22939624 24462205 16189514 17699868 20039095 16504566 20159553 17409432 16330544 15618521
HSP90AA1 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10744744 17145710 12441346 14743216
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
TRAF6 IRAK1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
IRAK1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 10346818 17145710 17785851 16024789 14625308 11259596 10383454 18234474 9374458 11287640 23244239 21220427 11518704 19166926 16951367 15894263 10747026 35926385 18056395 12566447 12496252 22447928 12242293 8837778 10920205 11960013 19716405 24735611 20043910 24434549 17785432 11397809 18347055 22033459 12140561 23381138 17197697
IRAK1 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 11518704 12242293 23331499 14743216
IRAK1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11518704 12242293 19675569 23331499 18180283 21071413 11259596
KSR2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12975377 23331499
RAF1 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 7565670 12750173 18799465 16364241 11909642 19219045 21988832 23331499 15342917 8933152 9671314 8393135 9808624 8223433 16189514 18988627 18669648 19541618 16293107 10969079 10567369 8157000 11136732 11948414 7898932 9069260 18039929 19369195 8607979 10327068 17116858 24746704 12920017 16129686 19058874 15466214
MAP3K3 MAP2K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 12912994 23331499 25241761 16861740 19903815 14743216 11073940 16189514 17985933 24975362 10593883 25861671 12813044
MAP2K5 MAPK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 7759517 11544482 24975362 23612709 7646528 23331499 16189514 11782488 12011113 30132833 12912994 15917464 11242034 32296183 29483645 11739740 20667468 9790194 12628002 25861671
RIPK1 MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TNFRSF1A MAP3K1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
MAP3K1 TNFRSF1B â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531 9379049 9582321
RIPK1 MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TNFRSF1A MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 MAP3K1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
MAP3K1 TNFRSF1B â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 10465784 11274345 11668179 12048245 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23850759 24378531 9379049 9582321
RIPK1 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11369754
TRAF2 MAP3K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10346818 17145710 25241761 16636664 10755617 18635759 25260751
NCBP2 METTL14 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
NCBP2 METTL3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9409616 24316715 24407421 24981863
PSEN1 NOTCH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11518718
PPP5C RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16892053 15664191
PRKCB RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8288587 1386920 12917261 22826029
PRKCG RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8288587 17053865
PRKCZ PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14576165
WDR83 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15118098 23331499
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TNFRSF1A â—¼   PHYSICAL_INTERACTION 30.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23070005 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TNFRSF1A â—¼   SHARES_COMPLEX 30.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 14730360 15170913 15592525 17462996 17496911 18641653 18855897 19392652 19524513 19632174 21133840 21232017 21614932 23010170 23070005 23850759 24378531 26587781 26653790 28574505 28765050 9379049 9582321
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
SOCS1 RIPK1 â—¼   DOWN_REGULATES ✅ - 6.0 1.0 ACSN 10485906 12193701 12223527 12811837 21469115 23124025
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
TNFRSF1A RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 62.0 1.0 Omnipath 25681446 11002422 20547836 8612133 18450452 27552911 26802121 10356400 19773432 18621737 23815148 16611992 22179575 12721308 21741934 7538908 18949366 21113135 8985253 10744744 10795740 21119000 22733818 10755617 27321185 15115707 24098568 18939944 18329793 20825417 20448643 15357952 21737329 12887920 24130170 15258597 24758719 16115877 19524513 18724939 16968706 22817896 28817177 18022363 19815541 25388546 21331078 22848449
RIPK1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15327770 16603398
TAB2 TAB1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
TAB2 TAB1 â—¼   SHARES_COMPLEX 16.0 1.0 ACSN 10391247 11274345 12620219 14660645 14704854 14960582 15082531 17127310 17884187 18264787 18762249 18855897 19020754 19136967 20194509 23070005
TRAF2 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17145710 14743216
TRAF6 TAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21305609 17145710 11809792 12242293 19775907 10882101 25290089 10094049 30782845
TRAF6 TAB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF2 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF6 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 15492226 19675569 15932500 18180283 16251197 10882101 18299187 11259596 1551980 24061540 21988832 19112497 22924441 11518704 11809792 15836773 14633987 14751757 25290089 12496252 12609980 12242293 24735611 14982987 15327770 17720800
TRAF2 TNFRSF1A â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TRAF2 TNFRSF1A â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10465784 11112697 11274345 11279185 11668179 12048245 12531547 12556535 12646658 12655147 12738796 1330325 1431106 14607933 14625680 14730360 15099563 15170913 15310755 15592525 15699106 17462996 17496911 17916596 18633355 18641653 18855897 19392652 19411070 19524513 19632174 20038811 20184663 21133840 21232017 21411734 21614932 21826665 21920725 22955274 23010170 23070005 23170255 23430059 23510023 23567181 23769623 23850759 24092389 24378531 26201938 26587781 26653790 26801188 28574505 28765050 8663014 8910423 9379049 9582321
TNFRSF1A TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 26212014 8565075 8943045 8612133 16713569 16611992 22179575 11821416 7544915 12721308 21741934 10795740 21119000 19150425 27321185 25241761 15115707 18776134 15743837 15485837 20448643 12887920 24735611 20333651 18022363 19815541
TRAF2 TNFRSF1B â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23070005 23850759 24378531 9379049 9582321
TRAF2 TNFRSF1B â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 10465784 11274345 11668179 12048245 12556535 12655147 12738796 15170913 15592525 17462996 17496911 18641653 18855897 19392652 21133840 21232017 21614932 23070005 23850759 24378531 9379049 9582321
TNFRSF1B TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18429822 9168896 8548810 9162022 16713569 7859281 8069916
TNFRSF1B TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 8702708 10206649 16713569 8069916 7544915 18161752 14743216 9162022 15572357 18671942 9461607 8855313 11907088 8710854 11112773 15485837 9168896 8548810 7639698
TRAF2 TRAF1 â—¼   PHYSICAL_INTERACTION 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   SHARES_COMPLEX 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   ENZYMATIC_REACTION ✅ 49.0 1.0 ACSN 10820262 10925299 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 20038811 20184663 20435894 21133840 21232017 21411734 21826665 22955274 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 8910423
TRAF2 TRAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TRAF1 TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8702708 15383523 16713569 8069916 21903422 25996949 9500555 14743216 11181075 15323523 25241761 14557256 20385093 32296183 10544141 12887920 19287455 8548810 9718306 31515488 29748372
TP53 FN1 â—¼   KO_UP_REGULATES ✅ + 2.36 2.36 PKG 28854368