Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HSPA5 DDX24 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GFRA3 GFRA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA2 GFRA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GDNF GFRA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
RET GFRA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
ARTN GFRA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
PSPN GFRA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GRB10 GFRA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
GFRA1 GFRA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
NRTN GFRA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
H1-4 H1-3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-2 H1-3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
UBA52 H1-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-4 H1-2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-2 FXR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-2 FTSJ3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-2 NOP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SRC ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
FXR1 ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GRB10 ABI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
ABI1 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15048123 5216987
ABI1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
ABI1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7907811 20598684
ABL1 PPP3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10601328 19564926
ABL1 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
ABL1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 CUL7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 MKI67 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 G3BP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NOA1 AIFM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
SFN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20005908 8009659
AKT1 MTOR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17611497 18954143
KAT7 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212855 10930412
AR YWHAH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19996220 8009645
AR IRS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18521741 20610535
AR INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 20417685
AR IRS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19318566 20610535
AR RET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20587519 11255259
AR CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24218937 20610535
AR NEDD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18703514
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
AR HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 21125667
AR TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21303954 20610535
AR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12933816
GRB10 ARTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
RET ARTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA1 ARTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
PSPN ARTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GDNF ARTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
ARTN NRTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA2 ARTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
BTF3 RPL37 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
GRB10 CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
IRS1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15003536
INS CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28601906 25748795
CDC73 HSPA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CTNNB1 CTNNA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12640114 5216233
CTNNB1 IRS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15592430 12782598
PPP2CA CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10644691 19061640
CTNNB1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16219695
DCAF7 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
IRS1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 1845983
GRB10 EPHB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5221166 8798570
FLT3 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 9918857
PIK3R1 FLT3LG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19438505 11027663
FLT3LG GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31066629 23246379
FYN FLT3LG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7692230 26848862
FLT3LG GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19438505 23168613
KDR FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
MKI67 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
FYN PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12670391 8621607
KITLG GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16873377 18697750
KIT GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16873377 18697750
GRB2 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212828 10913131
MAPK3 GAB2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217186 15356145
RET GDNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
PSPN GDNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA3 GDNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GDNF GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
GDNF NRTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
RET GFRA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
PSPN GFRA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA3 GFRA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA2 GFRA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA1 GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
GFRA2 GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
GFRA2 PSPN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA2 RET â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
GFRA2 GFRA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA3 GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
PSPN GFRA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GFRA3 NRTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
GHR PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GIGYF2 GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20670374 12771153
PIK3CA GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31066629 23246379
INS GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12493740 14615605
PSPN GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
RET GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
IGF1R GRB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547677 9506989
GRB10 NRTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 7665556 8631863
GRB10 PDGFRB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10454568 6731105
GRB10 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
STAT5A GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23246379 16293640
ZNF239 GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12409453 11278819
OTX2 GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10354480 10372988
KLF15 GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15963234 15277472
SHANK2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PPP2R1A GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
KLF15 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3CA GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KDR GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
GRB2 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15637081 16893902
GRB2 GRWD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
HSPA9 GRPEL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KAT7 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21221131 15899857
UBB HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA8 NOA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HSPA9 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPB1 KLF15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PIK3R1 IGF1R â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6730400 7589433
IRS2 IGF1R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8662806 5221055
IGF1R YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
IL2RG STAT5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8709637 7489741
IL2RG STAT5B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8709637 7489741
IL2RG PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10421845
IL2RG JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8041779 24608040
IL2RG STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11418623
INS IRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9609109 15316008
INS IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9609109 15316008
STAT5A INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11415999 10373481
STAT5B INSR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 9428692 6730856
STAT5B INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10830280 15055356
PIK3R1 INSR â—¼   PROXIMITY 2.0 0.8 intact 6731120 10500481
INSR STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12456798
INSR PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8567177 8385099
SFN IRS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
MAPK3 IRS1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
PIK3R1 IRS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23617393 8427684
IRS2 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
MAPK3 IRS2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
JAK2 IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15316008 12960006
PIK3R1 JAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
JAK2 PIK3CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11598010 12506011
STAT5B JAK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17255200 11682625
PDGFRB JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8657151 9484840
SRC JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 17158356
KIT PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 7520444
KLF15 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK1 MAP2K1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 23241949 8412360
SRC MAPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
RAF1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
SRC MAPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16580177 9924018
RAF1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
NIFK MKI67 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216820 14659764
MKI67 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
UBC NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
OTX2 NRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21865162 24382353
PSPN NRTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
RET NRTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
PDGFRB PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 8702949
YWHAG PIK3R1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PIK3R1 SHANK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PPP2R2A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1328247 19114990
PSPN RET â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15044950 11491658
YWHAG RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
SHANK2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
UBC SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6504434 17936276
UBA52 USP9X â—¼   CLEAVAGE ✅ 2.0 0.8 Reactome 26235645 9521656
UBC YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
EGFR JUP â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
GFRA3 RET â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
EXOSC1 EXOSC3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
IGF1R PIK3R1 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
DDX24 GTPBP4 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
EGFR JAK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
NEDD4 AKT1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 19953087 23195959 31390487
PIK3R1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 16273093 5218056
DDX24 NOP2 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
BTF3 RPL5 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
GRB2 RET â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
PPP3CA PPP3CB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SART3 DDX24 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
P85A RET â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10652352 10995764 32062451
P85A GRB10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12783867 23246379
GRB2 1433G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21706016 31980649
1433G PERQ2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433G PERQ1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GRB10 2ABD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 31980649
BAG2 RAF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 31980649
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
WDR59 GRB10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RBM39 HSPB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25277244 28302793
SART3 RBM28 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RBM39 TOP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28302793 22939629
GRB2 PDGFRB â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EGFR STAT5B â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 11751923
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
GAB2 1433G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 19172738 33961781
GRB10 1433G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32814053 28514442 33961781
BTF3 UBA52 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
BTF3 RPL38 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
MAPK3 HSPB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21575178 8774846 25241761
INSR JAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12456798 8912646
EGFR GRB10 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
FLT3 FLT3LG â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
IGF1R INS â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
AR SRC â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
AKT1 IRS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10497255 17640984
NRL CRX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10887186 25703721
GRB2 HSPB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31980649 12577067
TOP1 NOP2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15848144 26344197
TRIP6 SRC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14688263 16189514 16713569
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
JAK2 STAT5B â—¼   PHOSPHORYLATION ✅ + 0.84 0.84 Signor 9575217
MAPK1 RAF1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
NRTN RET â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
GDNF RET â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
JAK2 STAT5A â—¼   PHOSPHORYLATION ✅ + 0.84 0.84 Signor 9575217
EXOSC3 EXOSC1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 20531389 7988290
GFRA2 GDNF â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10829012 9407096
SRC GRB10 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10871840 32814053 33961781
SRC GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12624098 9016807 16713569 16189514 11964172
PIK3CA IRS1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 34591642
KIT JAK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 7527392 9355737 8611693
PPP3CA RCAN3 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
IGF1R IRS1 â—¼   PHOSPHORYLATION ✅ + 0.85 0.85 Signor 17827393
1433G P85A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15324660 17353931
AKT1 P85A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16007092 19117013 10527852 28205554 28628118
KIT ABL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24728074 12374739
CAV1 INSR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31217420 10598578
CCNB1 FXR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29395067 26496610
GFRA1 NRTN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10829012 9407096
PIK3R1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 5220480 7642581
NIFK RBM28 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
GAB2 SFN â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
NEDD4 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NEDD4L UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
GHR P85A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9632636 17474147
P85A IGF1R â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8697095 25241761 7589433 8603569 7642582
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
NEDD4 EGFR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
EGFR NTRK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
EGFR RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
GHR GRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9632636 17474147
GRB10 IRS1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8621530 12783867
JAK2 RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8876196 9689060 11134016 10205168
SRC KIT â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24728074 12444928 12878163
NEDD4 UBA52 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GTPBP4 RPL37 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
FYN CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 12640114
IRS1 YWHAE â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
EGFR HSPA8 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EGFR SFN â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ABL1 ABI1 â—¼   PHOSPHORYLATION ✅ + 0.87 0.87 Signor 21320496
IRS1 JAK2 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
PPP2R2A PPP2R2D â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
YWHAE YWHAG â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
YWHAE YWHAH â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
GRB10 ABL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9006901 9747873
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AKT1 PIK3CA â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
KCNA3 CAV1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26931497 18218624 34196606
JAK2 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24240702 23838182 9363897 10358079 10635327 16273093
EGFR HSPB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23397142 15657067 24189400
NTRK2 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 9648856
JAK2 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10551884 16713569
NEDD4 IGF1R â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18632619 12697834 18286479 19165858
SRC RET â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32062451 10070972 16189514
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR STAT5A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 JUP â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ABL1 PIK3R1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
GRB10 INSR â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
HSPA8 HSPH1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
INS IGF1R â—¼   PHYSICAL_INTERACTION ✅ + 0.88 0.88 Signor 1851182
ABL1 GRB2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
PDGFRB SRC â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
GRB10 IGF1R â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GRB2 KIT â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RAF1 YWHAH â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DDX24 NIFK â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
KIT PIK3R1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RAF1 YWHAE â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RAF1 YWHAG â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
SRC P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19903481 23065768 32814053 23397142 10487518 25241761 24498420 19861161 16230374 12210743 16713569 7499252 12393736
P85A FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8394019 8294442 7520528 16713569 25416956
P85A JAK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8702385 16135792 17474147 10026141
ABL1 1433G â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25852190 15696159 16888623 28514442 30021884
1433G IGF1R â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15324660 27684187 17353931
PERQ2 GRB10 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16037382 12771153 20878056
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
CTNNB1 AR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5216126 12588987
GFRA3 ARTN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9883723 16765900
SRC CAV1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8632005 8910575 8621645 29720121
SRC FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16966330 31980649 28514442 19711372 9169421
RAF1 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7517401 16189514 16713569
GFRA1 GDNF â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9482105 20473317 9407096 8674117 10829012
GRB10 RET â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7665556 28794017
GRB10 RAF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9553107 10585452
RET GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7665556 10995764 15677445 9393871 8183561 32062451 16189514
KDR SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RBM28 NOP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 30021884
PIK3R1 SRC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
SFN RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 15778465 5217604
RBM28 TOP1 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
GFRA2 NRTN â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
EGFR PIK3R1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
GAB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
INSR PIK3R1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
AR CTNNB1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
IRS2 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12107746 9334184 15514089 26496610 8910607 19561084 12506011 23439647 11438664 9852124 21241768
ABL1 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8781408 8294442 16219545 16135792 19380743 17474147 1383690
P85A EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 21701776 7531698 31959764 22973453 8662998 25241761 16230374 7797556 25754235 25187647 16713569 7499252 16273093
P85A KIT â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17452978 10022833 1382595 7509796 25241761 12878163 24728074 16713569 9233773 7537096 11071635
1433G IRS2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28514442 15324660 17353931
1433G RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 10433554 16093354 31980649 17353931 25852190 10620507 11697890 28205554 28628118 8702721 16041367 28514442 32707033 16189514
PIK3R1 GFRA4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CA GFRA4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
MAPK3 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21419341
SRC ABL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11494128 12522270 11781820 17318191 17474147
GRB10 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9006901 23331499 9747873
ABL1 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19783996
MTOR AKT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11438723 22337773 18505677 21045808 15718470 30639242 19299511 24670654 21177249 22084251 23872070 10910062 18566586 22307628 14970221 25792870 18566587 21343617 25241761 29567957 26293922
AR ALDH1A3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 17526768
AR PIK3R1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22740037 12063252 20610535
PIK3CA ARTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3R1 ARTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
BAG2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14978028 12502846 8692945
EGFR CAV1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19446582 15657067 24658140 31980649 22411794 34079125 16407214 12354760 25402006 10781609 9374534 12388423 16799092 15273741
CAV1 PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10066366 11168929 23331499
CAV1 KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20462514 12529448 19923922
CRX NRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24382353 21865162 15001570
CTCF EPHB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
CTCF HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
CTNNB1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16288908 18952601 12810642
GRB10 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9006901 31980649 24658140 9506989 25402006
FLT3 GAB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19438505 11027663 23168613
FLT3 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17356133 12796379
FLT3LG GAB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19438505 11027663 23168613
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
PIK3CA GAB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3R1 GDNF â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
GDNF PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3R1 GFRA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CA GFRA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
GFRA2 PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
GFRA2 PIK3R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
GFRA3 PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
GFRA3 PIK3R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
STAT5A GHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12488452 15840840 17412814
GHR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17474147 9632636
GRB10 NOA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP63 GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
KIT GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17452978 10022833 17904548 12444928 7523381 10377264 24728074 16713569 8950973 7523859 8647802
KITLG GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8950973 16129412 10377264
JAK2 GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8536716 17474147 8950973 7500025
IRS2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19109239 7890616 9535722
INS P4HB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25091901 31184304 21308844
STAT5B INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10830280 10821852 10373481
MAP2K1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11160134
STAT5A IRS2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9837784 22509308 8861946
STAT5B IRS2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9837784 22509308 8861946
SRC KDR â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
KITLG STAT5A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11494148 10358045 9355737
KITLG STAT5B â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11494148 10358045 9355737
MAPK1 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP2K1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
PPP2CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
PIK3R1 NRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PIK3CA NRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PDGFRB PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 2466336 1374684 9739761
RET PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PSPN PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
PSPN PIK3R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
RET PIK3R1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
RAF1 PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 502464200 8203796 16239230
SRC PPP2CA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
RAF1 PPP2CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 502464200 8203796 16239230
SRC PPP2R1A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
PPP2R2A RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664191 23331499 16239230
SRC RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7517401 8876196 17097642 16189514 10205168
YWHAE RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8005785 11697890
YWHAG SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
SFN YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15778465 15324660
SRC VEGFA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
STAT5B STAT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15043997 17997837 14532269
STAT5A STAT5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21542777 15043997 17997837
AKT1 MTOR â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
GTPBP4 RPL38 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
GRB2 PIK3R1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
1433G IRS1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 30240640 28514442 15324660 33961781
EBNA1BP2 GTPBP4 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PPP2R2A PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20711181 8288198
GRB2 IRS1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
HSPA4 HSPA8 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
CTNNA1 JUP â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
NIFK RPL5 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
INSR IRS1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 7651388
NEDD4 GRB10 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 12697834 10446181 15060076
PIK3R1 IRS1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 6731578 14632132
IRS1 PIK3CA â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
IRS2 PIK3R1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
YWHAH RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8005785 11697890
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
INSR IRS1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
PPP3CB RCAN3 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
MTOR AKT1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 21592956
JAK2 STAT5B â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
PDGFRB PIK3R1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
EBNA1BP2 NIFK â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
EBNA1BP2 FTSJ3 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
FTSJ3 NOP2 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
PERQ1 GRB10 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 16037382 12771153 16713569 20878056
EBNA1BP2 NOP2 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
GTPBP4 RPL5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
ABI1 ABL1 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
MKI67 NIFK â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
GRPEL1 HSPA9 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
JAK2 IRS1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 15316008 11208867 9492017 12960006
PIK3R1 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7536927 6730373
PPP2R2A PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17245430 5219546
BAG2 HSPA8 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
GTPBP4 NIFK â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GAB2 P85A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 16253990 10871282 14530346 9660791 12506011 26839216 11334882 11782427 16135792 10068651 16219545
INSR P85A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10500481 11796522 8385099 7589433 1334490 8567177 7659087 8276809 9593725 14729945 15629149
PAF1 CDC73 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
RAF1 MAP2K1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 7014125 19197339
JAK2 STAT5A â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
MAP2K1 MAPK3 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
PAF1 WDR61 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
GRB10 NEDD4 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
P85A GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7544353 8621719 18346204 7642581 16219545 32814053 7642542 20936779 16713569 19380743 21706016 7759531 8647120 25416956 9541596 9174058 11418612 7737969 9886492
ABL1 ABI1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 12672821 9593709 11418237 18328268 9010225 17101133 8943360 20598684
CDC73 WDR61 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
IRS1 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8810325 21706016 7486683 8536716 8388384 8491186 22974441 12173038 7488107 7629070
PIK3R1 PIK3CA â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 20018188 7383613
MAP2K1 RAF1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ARTN GFRA3 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
INS INSR â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
NIFK NOP2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
GDNF GFRA1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
GFRA1 RET â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MAP2K1 MAPK1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GTPBP4 NOP2 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
GAB2 GRB2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
NEDD4 UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NEDD4L UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
IGF1R IRS1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
KDR VEGFA â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
CDH3 CTNNB1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
FTSJ3 NIFK â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL37 RPLP1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL37 RPL5 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL37 RPL38 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL38 UBA52 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPL5 UBA52 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
RPLP1 UBA52 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
P85A IRS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 8382612 8175658 7680095 17640984 23643389 16230374 26839216 7659087 9564850 14511371 12220227 7486683 1381348 15514089 22974441 12730242 16043515 16150444 16354680 16880210 12107746 30240640 33991522 19561084 8628286 14632132 25814554 7935461 7680644 8388384 29526746 11416002 1334490 23439647 12173038 25273559 11403293
RPL37 UBA52 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CTNNA1 CTNNB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
IRS1 PIK3R1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC73 PAF1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EXOSC1 EXOSC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL38 RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL38 RPLP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPLP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R2D â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PIK3CA PIK3R1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
MAPK3 CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17206380 25472841 12438317 15890648
MAPK1 CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10659854 12438317 15890648
PSPN GFRA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 1111614411116140 11116144 11544105
ABL1 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 17145710 20598684 18328268 12591740 9593709 20841568 18083107 7590237 11418237 12672821 17389395 19534553 8943360 17101133 9010225 11163214 26428302 21320496
MAPK1 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19917258 17855441 21419341 21900237
FYN ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12522270 16787943 17570479 16912036 16076903 17474147 11847100
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
ABL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 16099633 25164010 17618275 24465953 20841568 17318191 20840866
ABL1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12560071 20841568
ABL1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 11726515 16713569 20841568 8596638 16955467 10592173 8647802 8194526 7926767 14725908 23950177 8112292 9407116 23181695 19380743 17474147 9516488 19823681
ABL1 TOP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15448168 20841568
ABL1 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8940193 20841568
ABL1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24836440 8940193 20841568
ABL1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21071413 23331499 10753870
ABL1 RBM39 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27018250
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18083107 17389395 11094059 19534553 8632005 12531427 27292265 24632723 11075810 12036959 15592455 20841568 15951569 20808760 16151024
ABL1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16705159 15923602 15793561 25821558 9111318 15143187 16705160 11593427 20841568
ABL1 PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 14993293 19275932 20841568
MTOR AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
STAT5A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24218138 24469394 18042802 20385773
PPP2R2A AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 18039929 19216069 18077353 19556239 19996169 10026142 10995457 18042541 20452955 18559511 18588945 16680151 20360384 16406523
PIK3R1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10527852 16799564 19442713
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
GRB10 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11809791 15722337
PIK3CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 25793261 19117013 21041639 24950409 21816939
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
MTOR AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 24670654 16697215 11438723 21592956 20398329 17461779 18372248 21177249 21045808 20338997 15808505 16221682 20138985 20489726 15899889 20214616 8978681 21474067 14970221 19203586 17660512 15718470 19568798 20333297 23006971 15169778 25241761 18566586 19720745 17517883 18925875 22084251 10949026 14761976 11715018 19143635 17277771 18636226 10910062 15047712 9812896 18505677 21343617 19844585 17680028 19151919 18566587 9736715 23872070 10722653 20832730 18570873 17013611 17052453 12408816 15364915 11274345
RET AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12600984 15994200
INS AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 29432553 23912456 11679435 23866690 17335965 24646332 23798298
AKT1 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
AKT1 YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17570479 17640984 10497255
AKT1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11782427
AKT1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12740362 11042204 19593530 22983196 17510053 23397142
AKT1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20858269 23331499 20028971 11882383 21303971 17680028 20214616 22094462 17287208 17374729 20398329 21506126 21402455 12040186 19623618 12063252 18218901
AKT1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AR CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18535113 18673534 20610535 11916967
AR EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15305378 19318561 21613411 19258514 15650253 17242169 18692155 15288768 11556855 20610535
AR VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16007189 23369005 18768969 18612129 15003169
AR SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19305643 10454563 18687691 17108144 17079466
AR UBC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17409431 20610535 17721441
AR IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19318566 15033751 17202144 19250214 20610535
AR GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24931201 20610535
HSPB1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19767773 17974989
KAT7 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10930412 16713569
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
SRC AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 28144231 15062576 20570899 25133482 21318111 11032808 25950519 21512132 17525795 12933816 20383201 24728074 24948875 24868554 25547388 19117998 21956655 17045208 15027889 24859991 15466214 26829214 21886458
AR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 21741601 16713569 12799378 12944908 10809237 23331499 15060161 21071413 21885566 18988627 16428447 11916967 12588987 11792709 10987273 14593076 15256534 22187462
AR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18358509 12534934 22260327 15288768 18951974
ARTN GFRA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9883723 98837239883723 16765900 11544105
ARTN RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9883723
CAV1 SRC â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
INSR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9756945 10598578 12036959 17699617
FYN CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 9252391 29371975 11805080 12925753 21705803 12529448 11075810 15692085 14992595 8632005 10592173 16943184 12921535 16332692 12135605 20228056 15466865 33804982 24632723 33928090 18347068 34321069
SRC CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 20201820 23469926 24755228 24525631 15592455 27259249 17979878 19409422 11075810 17389395 14992595 18578522 11094059 11451957 24244013 8632005 24131997 12921535 21324536 16332692 8621645 18815812 27170175 17517963 12531427 24632723 23091071 19625610 18789131 24502576 17016520 20107068 21382479 24364863 25937636 19604397 23280667 16713182 22596063 26169283 8910575 17190831 18707149 25097454 12036959 18176934 15212693 18400052
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
CDC73 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 16630820 23331499 21726809 18988627 29774127
CDH3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8227214 10381631 12800191 21255999 11889072
CRX GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17760566 11934446 10348924 15277472 10866677 12409453 10354480
FLT3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17496910 22558232 17851558 12040186 19568798 22126602 14585353
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
FYN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 20026641 22264731 24511551 25241761 22340496 12640114 25803041 26509276
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
IGF1R CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17496910 22558232 12040186 19568798 14585353
CTNNB1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10477752 25241761 16219695 11716761
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
PPP2CA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
JAK2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17389395 10635327 17081983 10358079 16273093 16799092 18691976 10459005 9363897 15284024 23838182 17016520 18669648 15302935
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12556561 15531749
EGFR STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10830280 10358079 12411494 10558875 16729043 17016520 11751923
EGFR STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 31980649 10358079 24658140 25402006 18586824 16729043
EGFR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17496910 26918608 7797556 25241761 19531499 16273093 8662998 14967450 16713569 21701776
FLT3LG FLT3 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 10477595 14670306 15253381 15749884 16418395 16713974 17404308 20547845 25215878 8920882 9268501
FLT3 PIK3CA â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19805105 21827948 9918857 19438505 31066629 11027663
FLT3LG FLT3 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 10477595 14670306 15253381 15749884 16418395 16713974 17404308 20547845 25215878 8920882 9268501
FLT3LG FLT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 9651358 15618475 21389326 25992210 19830725 12681969 15147956 7505204 10080542
FLT3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10080542
PIK3CA FLT3LG â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 19805105 21827948 9918857 19438505 31066629 11027663
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
VEGFA FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
KDR FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
NTRK2 FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 16713569 9648856
PDGFRB FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 1696179 7685273 7687537 16713569 1661130 9425276
FYN GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10871840 16713569
FYN JUP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14517306
FYN KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9038210 9799234 12374739
FYN PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 8294442 8394019 7515100 17570479 16713569 7520528 1652056
STAT5A GAB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
STAT5B GAB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
GRB2 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
MAPK3 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12008033 15356145
GRB2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 17145710 16371368 25416956 21706016 15143164 10391903 19172738 10913131 11027663 9973481 10973965 20936779 10068651 11882361 32296183 16199887 24737791 15010462 19523899 16253990 19380743 31515488 11782427
SRC GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10391903 12464621 11640929 9885561
MAPK1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12008033 15356145
JAK2 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18644434 21183952
GAB2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 18950707 11334882 10068651 10982827 16253990 9973481 10871282 16135792 16219545 10973965 11782427 9885561 14530346
GDNF GFRA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9192898 9407096 9182803 91828039407096
GDNF RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23331499 14514671 8674117 9482105 23429478 9182803 22751117 25684228
GDNF GFRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 14514671 8674117 9482105 9182803 11106404 20473317 11544105
RET GFRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9883723 23331499 10829012 9192898 10774729 14514671 16189514 11106404
NRTN GFRA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9407096 9182803 91828039407096
NRTN GFRA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10829012 9192898 9182803 11544105 918280310829012
GHR JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8063815 23331499 10502458 17312100 21347402 18988627 7540178 9211920
KITLG GRB10 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16129412 10377264 11809791 9872323 8647802
KIT GRB10 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16129412 10377264 11809791 9872323 8647802
MAPK1 GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15952796 18220336 18669648 20068231
SRC GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10871840
RET GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 7665556 8631863
IGF1R GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19165858 8776723 8764099 8621530 12697834 9506989
MTOR GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15952796 21659605 21659604
INSR GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9506989 15664450 10871840 8621530 9006901 19648926 7479769 12783867 12493740
MAPK3 GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15952796 18669648 18220336
KIT GRB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11809791
GRB10 NEDD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12697834 23331499 10446181
STAT5B GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
STAT5A GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
GRB2 VEGFA â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 KDR â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 RAF1 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
GRB2 KDR â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 RAF1 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
GRB2 VEGFA â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
IRS1 GRB2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 16931767 17604717 19030972 21540285 22465479 24036369 8621421
GRB2 PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 VEGFA â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
KIT GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 24728074 8950973 7523381 10022833 7523859 8647802 16713569 17452978 17904548 10377264
PDGFRB GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7935391 16713569 7486683
KDR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9405464 16966330 10319320
IRS1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8265614 7862167 11788580 8388384 8491186 8536716 7488107 7486683 10358772 10592173 8196603 12173038 12679424 8114695 11259577 8810325
IRS2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7559579 11788580 10358772 11305324 9852124
JAK2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8536716 8950973 7500025 17474147 19273609
RET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9393871 16189514 15677445
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
IGF1R IRS1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10086337 10826997 11274345 12175651 12444011 12556535 12655147 12767520 16931767 17145802 17673906 19030972 21540285 24103846 24782617
NEDD4 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 18988627 12697834 19165858
INS IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 1851182 18988627
SRC IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17389395 15212693 18691976 7559478 7493944 7537849 20068231 23472139 8550552 17016520 8940173 9480911
IGF1R IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 8662806 9852124 10471495
IGF1R PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8603569 17496910 25241761 8697095 7642582 17570479 18595745 7589433
IGF1R IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 7541045 12444011 19030972 10082579 16931767 21798082 12220227 11259577 12767520 10826997 23331499 17827393 7504175 21071413 7559507 11572799 27856640 12175651 17570479 15829723 18988627 15629149 11557037 20670944 8530377 21540285 8776723 25886138 8662806
IGF1R YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12767520 10826997 12444011 21540285 17145710 17353931 19030972 16931767 15324660 12175651
IGF1R YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 16931767 9111084 12175651
JAK2 IL2RG â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL2RG IL4R â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10358772 10485906 10856136 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
JAK2 IL2RG â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL2RG IL4R â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10358772 10485906 10856136 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL2RG IRS2 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL4R IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17145710 11815609 12704343 23331499 18243101 8266076 8266078 7918378
JAK2 IL4R â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 1825141 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 2965306 7512720 7521688 7543512 9535722 9834059
JAK2 IL4R â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 1825141 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 2965306 7512720 7521688 7543512 9535722 9834059
JAK2 IL4R â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 14657224 15099563 16243976 16413922 17404308 17485448 18250477 1825141 18451175 19833085 20184663 20406969 20510870 20856220 21097505 21115385 21469115 21840487 23124025 23390297 24030977 24091328 26755705 27216177 2965306 7512720 7521688 7543512 9535722 9834059
IL4R IRS2 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IL4R JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8609418 18852293 12223527
IL4R IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8954948 12704343 8266078 10233717
IL4R IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9697832 8124718 8599766 12704343
INS INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8393875 21743783 21317886 24296476 26374090 29069585 26245346 16956584 19902173 20332342 23363978 23331499 18988627 23302862 22832498 2550426 15870194 11278498 19752148 29512653 23304064 24633815 17227660 22521887 23223021 30197476
INS IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25309812 25472611 23891856 20150288 29069585 24036112 21518983 11160134 19357636 22198320 17579213 21677282 11684411 23983791 28955049 25760026 21850561 22832498 19808019 22698915 23815272 18443205 20601126 16150913 25383313 27695421 23115649 22728334 19752148 19171749 27819676 16516141 22418434 19542202 25381390 22516431 24763529 26866272 23695665 23431498
INSR IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 19901323 7629118 9195949 18083107 23331499 19534553 7537849 17570479 18988627 7675087 11584304 7526222 12101187 8626379 8662806 8626723
INSR PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 15629149 17389395 8276809 18083107 11796522 8385099 20068231 8567177 16497976 15592455 17570479 9593725 7589433 14729945 17016520 10500481
INSR IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 10655627 7651388 25472611 1385403 18083107 12220227 23331499 28328746 7504175 19534553 7499194 7537849 7935368 11572799 11781100 10592173 17570479 17575262 18988627 12446583 15629149 10455177 15870194 11416002 12101187 17167487 8530377 8626379 8662806 11606564 2159922 8626723 16020478 16582879
MAPK1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 37.0 1.0 Omnipath 15001544 17081983 18949383 16123357 27014871 16914728 17360977 16099428 30401435 16131083 17640984 12510059 15613682 21850561 14579029 20594869 8626671 9395471 19651622 15576463 22289259 14769130 16020478 17242212
MTOR IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 22570710 15952059 19561084 21282364 25973388 14769130 11287630 9335553 17698034 20863384
MAPK3 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15001544 16131083 8626671 14769130 9335553 15613682 12510059 15212693 9395471 14579029
IRS1 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12767520 10826997 12444011 21540285 19030972 16354680 16150444 16931767 10592173 12175651 1380456 23643389 1381348 11313948 9374521 20966354 9624169
IRS1 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 12444011 11788580 14632132 14511371 19030972 16931767 7486683 21798082 11403293 12173038 8382612 12220227 12767520 10826997 16230374 7680095 23439647 19561084 16150444 12107746 10358772 11748924 12175651 7499365 7935461 15316008 9564850 16354680 16043515 12730242 11416002 7680644 23643389 21540285 8628286 15514089 11438664 8175658 9233603 1381348 25814554
IRS1 JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9492017 7782332 11208867 21071413 12960006 15316008
JAK2 IRS2 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 10485906 11160275 11371360 11867689 11870632 12223527 12401408 12496409 12818165 14610620 16243976 16413922 17404308 17485448 18250477 1825141 19833085 20184663 20406969 20510870 20856220 21469115 21840487 23124025 23390297 24030977 24091328 27216177 2965306 7512720 7521688 9834059
IRS2 PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9113989 22810696 9374521
IRS2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21241768 23439647 11024460 19561084 12107746 9334184 15715521 11438664 15514089 26496610 9233603 23617393 8910607 9852124 19109239
SRC JAK2 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11476890 12094222 16919435 17496910 17517963 25572304 26552706 27216177
STAT5A JAK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10882725 7744007 21719533 19036881 9343435 9698919 11713228 19638583 16847321
KIT JAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8611693 7527392 15526160 9355737
JAK2 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17081983 34197875 7925280 16497976 15795318 18083107 17389395 23331499 15504549 19534553 9047382 21071413 11641791 18988627 8617237 18250158 19088846 15256422 12529425 28676702 11413148 17016520 9575217
JAK2 PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8702385 12706299 16135792 17474147
JAK2 PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11440634 7651724
JAK2 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 11134016 8876196 9689060 10205168
JAK2 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 9047382 21071413 12538627 26959975 24354892 16306356 18988627 12456798 9575217 11682625
SRC JUP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8081883 14517306 23911551
SRC KCNA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11812778
NTRK2 KCNA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19166614 26655221 11812778
VEGFA KDR â—¼   PHYSICAL_INTERACTION 58.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
VEGFA KDR â—¼   ENZYMATIC_REACTION ✅ 58.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
KDR PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SRC KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19050761 18662404 18194650 10749680 12509223 18377662 10455194 16966330 12214271
VEGFA KDR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 22897854 15637071 1417831 23374253 12716911 18325345 16763549 31023826 8356051 16901919 24023956 17658244 20145116 8621427 11333271 16423422 22174934 16633338 11181169 27005951 9556609 8631822 17318185 12189247 31932617 23583373 20660291 19818105 24966171 21596751
KIT STAT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
KIT KITLG â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 12490555 14623871 15099563 15337769 16510505 16831886 17093497 17550342 18524989 18633355 18832382 20731704 21199805 21317430 22406545
SRC KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12878163 7520444 10523831
KITLG KIT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17662946 1698556 7680037 12036870 7536489 25717186 26358753 17259966 1375232
KIT STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10358045
KIT PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9092574 17496910 1382595 11071635 25241761 24728074 7509796 7537096 12878163 10022833 16713569 7520444 17452978 9233773
KIT STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10358045
PPP2CA MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18039929 16680151 1716348 10995457 18042541 18588945 20626350
RAF1 MAP2K1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 143.0 1.0 Omnipath 10757792 18337766 18799465 15342917 23728975 26496610 15866172 17053865 11242034 9351825 9677429 8157000 7992057 11948414 11604401 16129686 10677502 12695496 19197339 7565670 12750173 7936666 1326789 19219045 23331499 18556463 10976102 18988627 15485920 15175348 18691976 16407412 10409742 9311917 17192257 7898932 8621729 23934108 11684694 21336309 7624324 12920017 11948406 15466214 11042690 12907640 9032297 27169363 12876277 8933152 8223433 8248196 8131746 12594221 10969079 10567369 17979178 17724343 24746704 19058874 10958680 8090753 21071413 7731720 7873542 1330321 8503013 16093354 19541618 8394352 15466476 25155755 11136732 9069260 94178255 8607979 10327068 10359597 8039496 20212043
MAP2K1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 9694850 17081983 11319218 18799465 17389395 9447970 15342917 8226933 15851026 12270934 12644307 11242034 1381507 17906627 9677429 11986622 8376945 7992057 11948414 7687743 9731057 19197339 11704645 7565670 12750173 12932319 8626767 23331499 12048245 7559390 17272394 15811950 26987942 19494114 18669648 18691976 17192257 8388392 7898932 16464493 19369195 12920017 15466214 19690332 11134045 19534553 10995751 7867743 8223433 8248196 10567369 19933846 17563371 1518847 11730323 18983981 16186792 16135787 15951569 19058874 15212693 10748187 9560161 9925641 9733512 18083107 11104681 9006895 17569879 21071413 7731720 1330321 93330262 19541618 15466476 12925710 11971971 11136732 11118451 10746662
MAP2K1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 149.0 1.0 Omnipath 21675959 9694850 17081983 10757792 11319218 18799465 15592455 12788955 19415658 12697810 17389395 9447970 15342917 8226933 15851026 12270934 12644307 17255949 10998418 11242034 1378617 1381507 17906627 11986622 8376945 8157000 7992057 11948414 9731057 19651622 11251083 11266467 18707149 14743221 11279118 11704645 12750173 12932319 16497976 11337027 23331499 12048245 7559390 17272394 15811950 19494114 18669648 18691976 11741894 15972258 19053285 16094384 17192257 7898932 24623782 9166761 19369195 21336309 12920017 15466214 17016520 19901323 1712480 19690332 11823456 9032297 11134045 12876277 19534553 10995751 20068231 21506533 8223433 8248196 16153436 12594221 10567369 19933846 17563371 11730323 29175850 11352917 16135787 15951569 19058874 15212693 23241949 9560161 91184134 18083107 16887817 18578522 17569879 21071413 9148935 18452278 1330321 8670897 19541618 10777511 15935618 12925710 11971971 9765155 11136732 11118451 12082107 12952943 10746662 21768338
RAF1 MAPK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
PPP2CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 10592173 7780739 18588945 2154696 20626350
RET MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 19901323 11522789 91184134 16156666 16497976 15592455 12571246 19415658 11826406 17389395 18578522 21109534 20068231 18452278 18669648 16153436 11522288 18691976 1378617 15972258 15935618 16094384 12388769 11971971 19651622 21842857 28450419 18707149 17016520 21455180
MAPK1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9804779 25241761 18775330 10194762 8226933 10996427 9604935 8388392 12091337
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17081983 18767875 15849194 19690332 11409918 14654779 23331499 23180781 8226933 20068231 18988627 21917714 18669648 19541618 18691976 16407412 19933846 9922370 15664191 8388392 19651622 10801873 8349614 18775330 9604935
RAF1 MAPK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
RET MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 551.0 1.0 Omnipath 15956760 25485910 17240116 20385359 12527803 17621270 23612968 18212246 21860413 18097051 18851832 10645003 25679764 21423210 15007380 19934253 19935718 22356909 9677429 15781651 10849428 17188005 20667468 14625304 34380633 17377139 21423211 20010870 26186445 20736304 12376318 33627405 16740736 21561860 15004239 17901130 15212956 15897464 15143154 18819921 17157789 26297582 12138104 11777927 22158866 23195225 34473994 20494825 14963038 16778204 17391526 27683117 22689060 12444552 31933886 15059947 26823016 15657432 19377875 17142325 15486045 21460222 23431142 11159838 27654866 19941816 14718389 34375550 18593598 17360704 23997214 24501773 16163708 10604992 15297577 17106060 24396487 25893857 20361349 16822962 12554776 18454177 29434871 34530870 16141331 12356731 19169277 20543098 17685427 21478906 18463290 16250012 20534535 21228323 7535768 26617336 15963258 10617652 17196532 19995915 10464310 15315965 12082540 21685939 25730857 18305109 25703330 16928771 15681433 11083859 16076871 20395206 23146907 26246800 21454539 12660819 21220474 15866871 15637081 19858202 34403210 18032526 16195541 21829454 16459330 17209045 12808105 11585739 16162500 25833830 18246127 11864968 24418169 15935618 19925796 20160123 17056593 14998784 18215133 10508618 18775330 18760948 12952943 21768338 17317777 8155326 22258404 15788397 26919095 28213521 21192818 33798093 15851026 26242183 12402043 21868357 17064352 20927383 16380505 15035987 21454675 18957207 19193766 21188622 19050043 16904111 19888469 26073130 20185553 15282551 16790523 23405013 11994288 17510392 32081857 18941537 20930115 19106095 11043579 21499301 20145126 24427291 10958690 15939799 19088846 19286657 18424438 15308678 18198175 27323814 24338688 24252946 19956644 21478903 12014987 23017243 17525129 12511559 17615152 16505244 20122898 12077249 17123942 26035354 11278407 15665049 20531297 17292825 14976148 16449644 16461767 23361053 19261611 11502744 25658205 12149254 30327409 17560175 24352879 26586479 26804906 25779944 34125833 19118012 11352917 16740725 11884401 16464862 16641227 27323830 18063582 22955283 24561529 10779765 10542198 16135812 23564461 17210721 24469048 24803537 21602434 17110601 21045017 11073973 10597231 23687376 34556812 17341659 18692468 17579083 12384403 21408150 25417160 11752053 23325789 17371847 11970985 22327338 26265441 16840783 17283152 26616862 23188829 17239630 21487005 11024037 17053147 24363437 25682201 20234004 12391272 23644655 25638159 20808799 17922836 20129247 24913355 18451171 25483104 26296889 21081844 17404396 11287604 18263590 26317416 15541367 16467309 12765939 16331263 16498402 20485667 11230338 16387841 19543320 7687743 20228268 15630487 16774943 16710359 10803464 16844778 16574647 15994317 17495961 21215800 17590453 26382850 19002495 12909616 20599567 12558965 10667594 24711455 17255109 16038803 12370087 21072043 20008839 18805968 10206983 11875080 20231899 21499296 21908610 16002410 12821943 24292678 17525735 17928416 21057531 25236495 17283137 21659545 24403530 16919488 23378338 22973961 18847491 16682955 20840866 16153436 23542175 24492000 12526087 26556867 12133965 12433918 20065107 14610044 11959800 15580310 21730285 11046056 9124279 14707024 26725216 16452220 22212957 25811962 15696170 11416124 20498373 17157787 21653826 16149052 20022946 34262144 16434970 10558990 18045996 10925301 16280323 25581518 15899879 21441955 20566643 15466476 15657177 11706017 15059847 8444886 18519681 23528009 33513601 20138986 12368275 24608435 17062641 20082306 20375017 17537990 24567333 33820494 10712263 21278199 19011679 20145145 27582276 25640183 21730054 16177091 17250586 15879307 16728403 18299328 24269888 17303383 9482941 17671177 17173941 24095720 15304500 12874275 33828192 11827968 33731431 10799542 15328343 18838481 19036157 17634226 17110082 17855349 31722981 26079947 25002506 14559232 23584478 18593910 17114467 16373398 16931794 17016429 14676826 28415597 12029087 24269383 8626767 20478260 12097262 14764579 12181310 15100319 12384432 15271996 17562849 19036927 19326083 20072652 25940440 11922392 17913704 19494114 25596730 18938240 27449290 12897059 21478911 21123455 26804170 10940302 16624816 26876209 12048182 17150968 21478863 17307705 18658095 24995980 16582879 17289590 33667549 17209041 17890097 21726627 27662093 16843264 19426503 11103941 11940578 17906618 26234813 19029090 15007386 15958730 12576312 17667937 17785202 34480897 20647329 18941890 16446383 25562429 10867021 26985018 16413470 23178720 25578563 34437586 21738699 21258408 20388777 24681954 20459645 12242309 15289328 21575862 16185843 19147767 34497368 19153083 12124352 17371994 17567959 15611080 17297454 23012246 14557270 28542650 15713673 21129803 19460345 10958798 21772273 21900206 19205871 17591920 19217381 12963813 19718025 24469056 16624867 21149447 15728578 33902596 11971971 16455819 19112174 10751321 1835084 11016927 18267069 20410276 21980390 17409387 23831578 21477078 15558056
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK3 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 9804779 20508164 23331499 24263804 18775330 10194762 12407017 8226933 17502367 34188118 9604935 18988627 31932645 8388392 12091337
MAPK3 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 14654779 23331499 19541618 18691976 16407412 19933846 9446616 9922370 15664191 18988627
NRTN RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9192898 9182803 91828039192898
PDGFRB PIK3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 10752619 8564419 1372092 7486683 7692233 7536927 16713569 11710529 8382612 8086421 11896612 8670861 8388538 9153411 1330535 17496910 1314164 16135792 7680644 19864249 10697503 15377662
PDGFRB SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15489898 18315570 16189514 9010229 2173144
PDGFRB STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 9484840 25241761
SRC PIK3CA â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 12682286 15314172 20861220 18657504 11689445 12431978 25587652 11044445 22266855 11029403 11029009
SRC PIK3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12750372 10592173 17275257 10830300
VEGFA PIK3R1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SRC PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 25003662 10978272 21292165 23796501 24676687 22771321 24395787 17635907 26378614 16286244 27013170 23222956 25726524 24997451 31992581 12921784 1325671 17303700 23251465 20558158 21554241 23926298 25931585 22299660 18208556 21791414 23436320 32130916 17394530
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18039929 7604263 16680151 16239230 10995457 18042541 18588945
PSPN RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11116144
YWHAH RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12801936 11697890 8702721 17979178
SRC RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7692235 12551923 7517401 17097642 15258589 9689060 16189514 16630891 10998357 11376654 29063113 8876196 10205168 28846113 12952943 22592532 11134016 15710605 16170185
RAF1 YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17353931 11697890 8702721 10433554 16189514 15664191
RAF1 SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16093354 26578655 35044719 16041367 15778465 11697890 25852190
RAF1 YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19608861 16093354 16041367 11697890 8702721 16189514 25852190 7644510 15459208 17979178
SRC RET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11713247 17570479 16189514 10070972
TP63 SFN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12640112 17404570
SRC TRIP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16880273 21689746 15988003 14688263 23576104 17591779 27134758 16713569 20876301
SRC STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19438593 12429742 17997837 12621061
SRC STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11413148 17081983 10358079 22090359 7925280 16189514 15702476 11641791 15212693 8617237
YWHAH YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178
YWHAG YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 20936779 17085597 12507503 17979178
YWHAE YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20936779 12507503 7615088 26496610 17979178