Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H2AZ1 USF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PARP1 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
EP300 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
HBB HBA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HBB HBA2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MYC PTPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12747840
CTCF PTPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
YY1 PTPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1078742 10585862
H3C2 PARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
PARP1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
H1-4 RPL14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-4 GPATCH8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-4 ZC3H11A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-4 HP1BP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ACIN1 PNN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ADNP RPL31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AGO2 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
AGO2 TOP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
NPM1 AIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPS6KB1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
AKT1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
CTCF ANG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24659782
PARP1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16647857
SMAD3 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11906909 16603637
BCR CFTR â—¼   COLOCALIZATION 2.0 0.8 intact 5217253 15494376
KPNA2 CDKN1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7993392 20551905
TRAF2 CDKN1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PAX6 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20053773 17157287
SOX2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469032 22855803
EZH2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980972 21765901
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
EZH2 CDKN1C â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22821416 19340297
EZH2 CDKN1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
TAL1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14651981 20194619
YY1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22025288 18558095
EZH2 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
CTCF CELSR3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25113559
PARP1 CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
CTCF DNAJC21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YY1 CTCF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9756895
CTCF SIX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11479593
CTCF WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24534946
EP300 DDX17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20663877
MYC DDX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
EEF1A2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15752709 18064385
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
YY1 EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19483472
EPAS1 KDM5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14695898 18252963
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
EZH2 MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19749796 23349306
NCL FBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18292223 0712387105
FXR2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 HNRNPM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 HNRNPR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SMAD5 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
RUNX1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16995417 12835475
SMAD1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
MYB GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17641686
SMAD3 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11790301
KLF15 GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15963234 15277472
KLF8 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10756197
SMAD4 HDLBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
HNRNPM RPL7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SNRPA HNRNPU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RNF113A IK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
IK LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IK SNRPD2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RNF113A ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
SMAD3 KANSL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
KANSL1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KLF16 SIN3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438660 12036432
YBX1 KPNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20596676
MYC KPNA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 35044719 17093053
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
ZBTB48 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYB TAL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1259037 25394790
TAL1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22897851
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
NCL MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10660576
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
MYC NOP56 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
MYC TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15466196 12080469
MYC YBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
NCL WIZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STAB2 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 TAF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YY1 NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16170350 9092633
PARP1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PAX6 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23970099 19618119
SMC3 RALA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RALA SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SRPK2 RBM39 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RNF113A SNRNP40 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SMAD9 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SNRNP70 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SNRNP70 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
WT1 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20842112
SNRNP70 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD9 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SMAD5 SNRNP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SNRNP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMC3 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
USF1 TRIM25 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9714786 9245730
ACIN1 RBM14 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PNN SNRNP40 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
IK SNRNP70 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DDX5 SYNCRIP â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
HNRNPM PNN â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
KPNA1 SOX2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
MDC1 LMNA â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
SNRNP70 TRA2B â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HCFC1 RBM14 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
BCL2L2 SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RNPS1 TRA2B â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ACIN1 THRAP3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
IK RBM14 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
H3C2 DNAJC9 â—¼   PROXIMITY ✅ 0.81 0.81 mint 25281560
CTCF PARP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 14759373 20038529 19450526
DDX17 EP300 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 33742100 20663877 19995069 17226766
SMAD1 DDX5 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18548003
SRPK2 RNPS1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 22365833 8293266
RPS6 RPS6KB1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
AURKAIP1 MRPL11 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
SNRNP70 SRPK2 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ACIN1 SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN RBM14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL10A RPL14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RPL14 RPL5 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
IK SNRNP40 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
ACIN1 IK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN SRSF4 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
MYC BCR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 32140074
ESR1 CAND1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
CAND1 RBM39 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28302793 21145461
CAND1 STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30948266 21145461
CFTR STAU1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
MYC CHD7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
CHD7 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20130577 34079125
MYC CHD8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
SMC1A CTCF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33196849 18219272
DDX17 CTCF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30459231 24725430
MYC DDX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
STAU1 DDX17 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29374155 23125841
MYC DDX21 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
DDX21 RBM39 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28302793 22939629
STAU1 DDX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29374155 23125841
EPAS1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23275444 22807441 15261140 25689462
EP300 SMAD5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16613856 16516194
EP300 KLF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
ESR1 PURA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ILF3 RBM39 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28302793 22939629
MYC SMC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC SMC1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
MYC SYK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC TOP2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC RNPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RUNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
STAU1 NOP56 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29395067 30948266
PARP1 TOP2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16794079 34079125
STAU1 RALY â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RALY RBM39 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28302793 22939629
SMAD3 RUNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10531362 15897867
SMAD4 SMAD6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15817471 9256479
SOX2 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26186194 23667531
SOX2 TEAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
RBM39 SAP18 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
ACIN1 SNRNP70 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DDX17 HNRNPM â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
IK PNN â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RPL14 RPL7 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RPS6 STAU1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
PNN THRAP3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DDX17 SAP18 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
NPM1 RPL5 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
RPL13A RPS6 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MRPL11 PTCD3 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
RPL13A RPL14 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SRSF4 TRA2B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SAP18 SNRNP40 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
AURKAIP1 MRPS22 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
PARP1 CENPB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12011073 16713569
CFTR BCR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17110338 15494376
STAU1 DDX27 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29395067 23125841 30948266
KLF15 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 23999430 35016035
ESR1 SRPK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 31527615 21182205
ESR1 SRPK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 31527615 21182205
EZH2 SIN3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27634302 24981860 27705803
MYC HCFC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31767764 30415952 35140242
STAU1 ILF3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29395067 23125841 15303970
MYC LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
SMAD3 MEN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 11274402
RBM14 PARP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11443112 16713569
TEAD1 RAD51 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RBM14 RBM39 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28302793 22939629 26344197
PNN TRA2B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
IK SAP18 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MRPL11 MRPS22 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
MRPS5 PTCD3 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
SNRNP40 SNRNP70 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
MDC1 CHD7 â—¼   KO_DOWN_REGULATES ✅ - -0.84 0.83 PKG 28854368
DDX17 RBM14 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RPL14 RPL18A â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
AURKAIP1 PTCD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ESR1 DDX27 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 21182205
SRPK1 DDX5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 32707033
EP300 ILF3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 20808282
ESR1 EZH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
ESR1 SET â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 RXRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9121466 23403292 9717844
ESR1 PTCD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
MYC HIRA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21150319 23602572 29467282
LMNA MDC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30179224 30419336 22412018
LMNA PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 25948554 30419336 22412018
MDC1 RAD51 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28973861 16186822
NCL STAU1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
SMAD1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15761153 9111321 18729074
SRPK2 SNRPA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23602568 32707033
AKT1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 0.84 0.84 Signor 18423396
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HNRNPM RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPM SNRNP40 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PNN SNRNP70 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RBM14 SAP18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PARK2 TRAF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
ACIN1 PNN â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RPL5 RPL7 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16917507 14752096
STAU1 FMR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15121898 15303970 30948266
HCFC1 MEN1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23508102 24981860 15199122
HNRNPU POLR2A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
KPNA4 SOX2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NOP56 RPS6 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
FBL NOP56 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
SMAD4 SMAD5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
SMAD1 SMAD6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
MDC1 HMOX1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
SMAD4 EP300 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18215124 25514493 10887155 22033265 9679056 14612423 9843571
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
SRPK2 FXR2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29395067 26167880 25416956 32707033 34133714
TAL1 GATA3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21179004 9819382
PARP1 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20085707 34079125
TAL1 RUNX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19497860 21179004
SNRNP40 SNRPA â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HBA2 HBB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
RBM14 SNRNP40 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
MYC ADNP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
RXRA BCL3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16713569 9812988
SOX2 CHD7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 28794006 23667531 21532573
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
NOP56 DDX21 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26496610 12777385 34079125
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
KLF9 SIN3A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 11438660
MYC RBM39 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
RNPS1 RBM39 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28302793 26344197 17353931
SMAD5 SMAD4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10531362 16189514 15231748 16516194
SOX2 SMC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
SRPK1 SRPK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21157427 32707033
SYNCRIP YBX1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RNF113A SNRPD2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
FBL RPS6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SMAD3 SMAD9 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
BAX BCL2L2 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
AKT1 CDKN1B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CHD1L PARP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CFTR LMNA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26618866 29924966 17110338 31324722
CHD7 CHD8 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 24705355 20453063
NOP56 DDX27 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
RBM14 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11443112 16713569 33742100
ESR1 GATA3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
SAP18 RNPS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 16537548 26344197 22388736 12665594
RNPS1 SNRPA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26496610 17353931
SIN3A TAL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11118214 10688671
TRA2B SRPK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23602568 32296183 32707033 26167880
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NCL NPM1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HNRNPU SYNCRIP â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
RNPS1 SAP18 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RPL10A RPL5 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
SMAD3 DDX5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18548003 15464984 19917253
EP300 PAX6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10506141 35140242
MYC NOP56 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282 17353931
SRPK1 RBM39 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28302793 23602568 32707033
SMAD6 SMAD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9256479 12857866 9436979 11483516
STAG2 SMC1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17112726 10931856 29867216 26344197 24981860 26496610 23242214 31010829 19629043 29263825 17113138
CDKN2A NPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
FMR1 FXR2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
TNF TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
PNN RNPS1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ESR1 H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19515975 23108396 20023423
KDM5B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 17909537
AURKB H1-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21511733
AKT1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25241761 16362038
POU5F1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284 20683952
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
SMAD4 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15886208 16603637 18620728
MYC BCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
PAX6 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20053773 11584062 17157287
LHX2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
ZBTB33 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
GATA3 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
CTCF RAD21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19369356 19826084
HDLBP CTCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31917284 24725430
SMAD4 CTCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12099698
ESR1 DDX17 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11250900 25604459 19995069 20663877 21182205 12738788 20348541
SRPK2 DDX21 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 23602568 26167880
DDX5 EP300 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33742100 12527917 19995069 20663877
EP300 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527917 20663877
EP300 TAL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11118214 10490830 11756538
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
EP300 KPNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10801418 15342649
EPAS1 POU5F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20139178 19755485 16510872
RBM39 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15694343 11704680 33731348 21182205
ESR1 RPS6KB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22286763 21292829 18414489
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
USF1 FMR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15175277 18782566 11058604
MYC FXN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
YY1 HCFC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8661027 23000143
PARP1 KDM5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20832725 33859667
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
LTA TRAF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8663299 9122217 12571250
MEN1 SMAD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22275377 11274402 15150273
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
WT1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7559553
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
SMAD1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 15576399 22290435 22761862
WT1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15286719 17634147 20842112
MYC RBM39 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12080043 18414489
MYC RPS6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RPL13A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC THRAP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840 12808131
RNPS1 SRPK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 28514442 23602568 32707033
RNPS1 TRA2B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14729963 26344197 17353931
YBX1 SMAD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12917425 12446674 16278212
SMAD6 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9892110
YBX1 SMAD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12917425 12446674 16278212
SRPK1 SNRNP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12417631 23602568
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
AURKAIP1 MRPS5 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
RPL18A RPL5 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
RPL13A RPL5 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ACIN1 SAP18 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
SMC1A SMC3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
RPL18A RPL7 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
RPL10A RPL18A â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
RPL10A RPL7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
RPS6KB1 RPS6 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 15809305
RPL13A RPL7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
TOP2B TOP2A â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 22939629 8710863
MRPS22 PTCD3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
MRPS22 MRPS5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
RPL10A RPL13A â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
SMAD4 SMAD9 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
STAG2 SMC3 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17962804 6178082
PNN SAP18 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RPL13A RPL18A â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
SNRPA SNRPD2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
STAG2 RAD21 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17962804 6178082
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
ACIN1 RNPS1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
POLR2A SMARCA4 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
SMC1A STAG2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SNRNP70 SNRPA â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MRPL11 MRPS5 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
FXR2 FMR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28514442 33961781 21653829 32296183 24981860 7489725 29395067 8668200 10567518 30217970 24778252 24722188 16713569 25416956 26949739
SMC3 SMC1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 24981860 22939629 26496610 31807710 30021884 21880767 17112726 10931856 26344197 11590136 12759374 17349791 9789013 23242214 11877376 18832153 27173435 31010829 11076961 22885700 21111234 17113138
SMC3 STAG2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
MRPS5 PTCD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
SNRNP40 SNRPD2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
FBL NOP56 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SNRNP70 SNRPD2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
POU5F1 SOX2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL10A RPL13A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL31 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RAD21 SMC1A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 STAG2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPL14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPL18A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL14 RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL18A RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL18A RPL7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPL7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL7 RPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL10A RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL31 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL31 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL18A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPL31 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL31 RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL31 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL5 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL18A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL31 RPL5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
MYC H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18414489 22055461 12695333 11085504
MYC HBA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2463629 12695333
PTPA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21159657 18039929 19216069 23109003 10026142 10995457 18042541 20452955 18559511 18588945 16680151 19405949 16227604 16406523
GATA3 H3C2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
H3C2 AGO2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462
SRPK2 ACIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21056976 23602568 18559500 22365833 17287340 19592491
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
GRB10 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11809791 15722337
AKT1 SRPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19592491
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 TAL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19406989 15930267
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
AKT1 HMOX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15581622
AKT1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 25241761 15104092 16362038 21071413 18988627 26297431 15048128
AKT1 ILF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20870937 18097023
AKT1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 22119715 11756412 16780593 11923280 16697215 16209941 12244303 20398329 18372248 14967450 18710949 15808505 26053093 20138985 14504289 20214616 12244302 17570479 18593906 23576547 23400686 12851486 15169778 24651496 19829074 25241761 10949026 16288292 11715018 18636226 19377290 9812896 12042314 17680028 10722653 20832730 18570873 12244301 17052453
AKT1 CDKN1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12925736 23421998
AKT1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11943559 23331499 25241761 21071413 12183455 15149849 11438723
AKT1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26763134 14766748 15642728 17525161
AKT1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23041284 24497960
AKT1 YBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17081983 32028981 33911076 26318844 33151228 20844753 27591085 17704806 21423216 19036157 31906126 15806160 24335958 34272387 33379356 19651622 31387591 16354698 19664994
AURKB CDC20 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23226345
AURKB RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19887622 19276349
BAX TRAF2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
BAX TRAF2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
MYC BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8845569 11103792 12695333
BCL2L2 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18981409 17289999 18178565 21199865 17452531
BCL3 TNF â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 10754326 10952726 11875494 12907458 14660645 14668329 15079071 15465827 15536066 15644117 16878026 17145890 17404308 17485448 19171876 20138012 23390297 23430059 7594497 8383323 8580069
BCL3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12907458 15465827 22782967 22798670 24130828
CDC20 SMC3 â—¼   UP_REGULATES ✅ 8.0 1.0 ACSN 12070128 15279786 17303408 17660363 18590585 21270334 23197039 7575488
RASSF1 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 14743218 19276349
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
RUNX1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12732181 18276842 21757616 10851069 12091906 23673926
EZH2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19954516 21572997 23289480 23826727
CTCF CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22025288 12524457 19340300
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
NPM1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16957780 20208519 15289458 16199867 16915296
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
CTCF CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19129223 22422629
PARP1 CHD1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22146311 19666485
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
DDX17 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19995069 21182205 12738788 20348541 19718048 20663877 25604459
DDX5 GATA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17495528 15343269 19718048 11682626 28539435 14675539
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EPAS1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15156561 15192019 19010893 15191799 19080330 20061373 9113979 16900513 20574527 10531360 21057546 21145972 11350893 16778202 23213445 11301389 20807755 9746763 9665461 11751212 12750296 24062466 11912213 16920734 17322369
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16267616 12400015 17272396 18252963 18497067 10866309 19420388 19398483 16249470 14647449 15774498 12208749 10995484
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
RPS6KB1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 29128895 23242584 22114931 23460185 19925796 19112174 7838153
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
GATA3 YY1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
MYC HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1904416 12695333 24725430
USF1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16943425 12000849 17970752 19704006 19491096
HMOX1 TNF â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17689680 22461508 23390297 6357187 8871614
MYC HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333 10600159
USF1 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7969144 8760880 18331200 15242350 2318208 2722866
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
MYC VEGFA â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
MYC VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19738061 19147754 17785433 22002305 18809243 19398483 12368264 23028984
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 20940401
MYC NCL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10606642 24951594 12695333 14519204 25018006 11983916
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
POU5F1 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20505756 12136102 17324942 15988017 17068183
STAG2 RAD21 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17145710 28430577 12034751 11590136 25173175 22885700 29263825
RPS6KB1 RPS6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 17053147 17081983 33676898 19339977 92042229 20484036 16286006 20647036 11438723 17360704 1737763 17121928 11108711 20227368 22408430 27312851 12668683 16083285 15051500 20146692 15471950 18423201 17570479 20039704 21460850 21602892 1985906 30034573 21233202 24662264 29892299 19720745 12586835 12713446 20464435 26824026 15809305 16810323 86287375 24396066 24578720 20616057 24205356 19203585 15905173 14993219 17726024 20832730 22530122 17052453 7705100 15358595
SMAD1 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10692396 17215250 22219353 22072987
SMAD6 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9256479 9335505 9436979 21071413 18988627 11483516 12857866
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15188178 18952601 20631490 22740248 21057546 15629128 11486006 15191565
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23184087 10944227 20797318 12622415 24625091 20631490 18505344
SMAD5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20957627 23331499 14534577 16516194 16189514 10531362 15231748
SMAD9 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20957627 25502805 10583507 31515488 16189514 15231748
SMAD5 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10692396 16436528 22219353
VEGFA SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
VEGFA SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
VEGFA SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
TRAF2 TNF â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNF â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNF â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
MDC1 PTPN14 â—¼   KO_UP_REGULATES ✅ + 1.0 1.0 PKG 28854368
MDC1 ALDH1A3 â—¼   KO_UP_REGULATES ✅ + 1.18 1.18 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368