Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SMAD3 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11906909 16603637
CTCF BBC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20818159
CTCF BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20733034
BCL6 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14654791 11914273
BCL6 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22422878 19487462
CCND1 RBL2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
KLF8 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21518760 12820964
EZH2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132185 21697275
TEAD1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20153295 22286761
CTCF CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18625744
POU5F1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25128069 23433354
RASSF1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12024041
KPNA2 CDKN1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7993392 20551905
TRAF2 CDKN1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
AKT1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
CDKN1B RBL2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11157749 9144196
PAX6 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20053773 17157287
SOX2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22469032 22855803
EZH2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980972 21765901
MYC CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24704206 26701207
TAL1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14651981 20194619
YY1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22025288 18558095
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
EZH2 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
PARP1 CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
MYC DDX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085504
RUNX1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16917507 5218981
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15752709 18064385
EP300 DDX17 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20663877
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
EP300 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
FXR2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 HNRNPM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
EZH2 MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19749796 23349306
RUNX1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29958106
MYC YBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
MYC SMARCA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24285714 24362264
MYC TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15466196 12080469
MYC NOP56 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
MYC KPNA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 35044719 17093053
STAB2 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 SUZ12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 TAF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 AIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YY1 NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16170350 9092633
H3C2 PARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
PARP1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
PARP1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
PARP1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16647857
H2AX RAD51 â—¼   COLOCALIZATION 2.0 0.8 intact 8149296 21317870
RNF113A ILF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
RALY RRP1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RRP1B CTCF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AX SMARCA4 â—¼   COLOCALIZATION 2.0 0.8 intact 7914327 20224553
SMC3 RALA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMC3 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
APP TNF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AGO2 TOP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
YBX1 KPNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20596676
YY1 EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19483472
YY1 CTCF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9756895
H2AX GPATCH8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ZBTB48 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LHX2 PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19146846 24262147
HBB HBA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
HBB HBA2 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
KLF15 GRB10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15963234 15277472
CTCF CNIH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
EEF1A2 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CTCF IPO13 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23620300
CTCF CRYAA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
PAX6 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23970099 19618119
SYK APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACTR3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD9 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD5 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RALA SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMAD4 HDLBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD4 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12099698 15242331
SMAD3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WT1 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20842112
SMAD3 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11790301
KLF16 SIN3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438660 12036432
KLF8 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10756197
RPS6KB1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
CTCF IRAK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15670593
RUNX1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16995417 12835475
SMAD9 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
BCR CFTR â—¼   COLOCALIZATION 2.0 0.8 intact 5217253 15494376
H1-4 RPL14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ADNP RPL31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CTCF APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YBX3 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10692164 12644490
HNRNPM RPL7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NCL FBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18292223 0712387105
NCL MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10660576
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 PTPRG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 EGLN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 11850811
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14695898 18252963
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
H2AZ1 USF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
USF1 TRIM25 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9714786 9245730
AGO2 EZH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19955415 0912384106
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EZH2 CDKN1C â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22821416 19340297
EZH2 CDKN1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
SRPK2 RBM39 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
CTCF EGLN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
EGLN2 EPAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788921 15474027
SMAD9 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SMAD5 GATA3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22219353
MYB TAL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1259037 25394790
TAL1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22897851
CTCF ELP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
EPAS1 KDM5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
CTCF WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24534946
MYB PAX6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9371644 7838532
MYB GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17641686
CTCF ASAP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23999061
CTCF ETNK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18632798
CTCF RBL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21325284
CTCF LYZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10480923 10940558
CTCF SMIM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
CTCF NCBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
CTCF CELSR3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25113559
CTCF PTPRG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21150880
CTCF FGF17 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
CTCF RARRES1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22615834
CTCF CTAG1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16140944 17260018
CTCF NF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21111075
H3C2 SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H1-4 GPATCH8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-4 HP1BP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DDX5 SYNCRIP â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
KPNA1 SOX2 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
SMAD1 DDX5 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18548003
DDX17 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 17226766 19995069 33742100 20663877
EP300 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18280497 16204234 19622798 12960163 24636898 33742100
CTCF PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 20038529 14759373 19450526
SRPK2 RRP1B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 26167880 33961781
EPAS1 EGLN2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 23275444 17353276 15474027
H3C2 DNAJC9 â—¼   PROXIMITY ✅ 0.81 0.81 mint 25281560
RPS6 RPS6KB1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
AURKAIP1 MRPL11 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ZCRB1 DDX21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MYC DDX21 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
DDX21 RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28302793 22939629
STAU1 DDX5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29374155 23125841
EPAS1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23275444 15261140 22807441 25689462
EP300 KLF8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 20107328
EP300 SMAD5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16516194 16613856
MYC RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC DDX17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC SMC1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC TOP2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC SMC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC BCR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 32140074
MYC CHD8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC CHD7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
MYC RRP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
MYC SYK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC PRR11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
CHD7 PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20130577
PARP1 TOP2B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 16794079
ZCRB1 PURA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ESR1 PURA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
RRP1B NOP56 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 20926688
RRP1B STAU1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 19710015
SMC1A CTCF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18219272 33196849
CAND1 STAU1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 30948266
CFTR STAU1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
STAU1 DDX17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29374155 23125841
STAU1 NOP56 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 30948266
STAU1 RALY â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
H2AX CTCF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SMAD4 SMAD6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15817471 9256479
SMAD3 RUNX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10531362 15897867
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
CAND1 RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28302793 21145461
ESR1 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ILF3 RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28302793 22939629
RALY RBM39 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28302793 22939629
DDX17 CTCF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30459231 24725430
SOX2 TEAD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 21532573
ZCRB1 CTCF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PRR11 CTCF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
SOX2 VPRBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23667531 26186194
CCND1 CDKN1C â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
RBM39 SAP18 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
RPS6 STAU1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
NPM1 RPL5 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
MRPL11 PTCD3 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
CHD1L H2AX â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 19666485
KLF15 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 35016035 23999430
CDC20 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 16319895
SMAD3 MEN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11274402 16189514
MYC LMNA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
PARP1 CENPB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12011073 16713569
TEAD1 RAD51 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PRR11 STAU1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
STAU1 ILF3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29395067 23125841 15303970 33961781
STAU1 DDX27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29395067 23125841 30948266
H2AX LMNA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20000738 25948554 23658700
EZH2 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27634302 27705803
AURKAIP1 MRPS22 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
CFTR BCR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15494376 17110338
ESR1 SRPK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
ESR1 SRPK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21182205 33731348 31527615
PRR11 DDX27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
PRR11 ZCRB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MRPL11 MRPS22 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
CCND1 EP300 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
AURKAIP1 PTCD3 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
SRPK1 DDX5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
EP300 ILF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20808282 33742100
LMNA MDC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30179224 22412018 30419336
MDC1 RAD51 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28973861 16186822
MYC HIRA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21150319 23602572 29467282
LMNA PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30419336 22412018 25948554 29568061
ESR1 RRP1B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
ESR1 SET â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 PTCD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182203 31527615
ESR1 RXRA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9717844 23403292 9121466
ESR1 EZH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
ESR1 DDX27 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
AKT1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 0.84 0.84 Signor 18423396
NCL STAU1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DDX5 ESR1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
PARK2 TRAF2 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
RUNX1 EP300 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14752096 16917507
EP300 SMAD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10205054 20851880 22365546 16613856 10673036
STAU1 FMR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 15121898 30948266 15303970
CCND1 CDKN2A â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
KPNA4 SOX2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NOP56 RPS6 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
HNRNPU POLR2A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
SMAD4 SMAD5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
SMAD1 SMAD6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
SMAD4 EP300 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 25514493 18215124 9843571 14612423 10887155 22033265
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
SRPK2 FXR2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26167880 25416956 29395067 34133714 32707033
ESR1 MEN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16651450 31527615
PARP1 TOP2A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 20085707
TAL1 RUNX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21179004 19497860
TAL1 GATA3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21179004 9819382
HBA2 HBB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
CCND1 ESR1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
RXRA BCL3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9812988 16713569
NOP56 DDX21 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34079125 12777385 26496610
MYC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15616592 16287840 32140074 16126174 17157259 12776737
AKT1 EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21901101 15224190 21775285 20333651 18182168 11116148
MYC RBM39 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
MYC ADNP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 29467282
H2AX RAD51 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31009828 30560944 21317870 28796254 29499138 28190324 10959836
SOX2 SMC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 28794006
SMAD5 SMAD4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10531362 16516194 16189514 15231748
SMAD3 SMAD9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15231748 33961781 26186194
KLF9 SIN3A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 11438660
SRPK1 SRPK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 21157427 33961781
SOX2 CHD7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 35140242 21532573 28794006 23667531
DDX17 DDX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SYNCRIP YBX1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FBL RPS6 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SMAD3 SMAD9 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
AKT1 CDKN1B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CHD1L PARP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EP300 CCND1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15951563 10567390 11788592
EP300 MYB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20364308 11585920 29954426 15691758 35140242 10656693 25740244
SIN3A TAL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10688671 11118214
CFTR LMNA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26618866 31324722 29924966 17110338
NOP56 DDX27 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 26344197
ESR1 GATA3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 26153859 23403292 25303530
CHD7 CHD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20453063 24705355
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NCL NPM1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HNRNPU SYNCRIP â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CDKN1B CCND1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 34591612
CHD1L PARP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19666485 33053171 22146311 34079125 23926104 19661379
RRP1B DDX21 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20926688 33961781 19710015
SMAD3 DDX5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15464984 18548003 19917253
EP300 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 10506141
MYC NOP56 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17353931 17314511 30415952 29467282
H2AX PARP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16377563 20000738 27728808 33961781 28796254 18406329 28242625 16522924 20085707
RRP1B ILF3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29395067 33961781 19710015
IPO13 PAX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 15143176
SMAD4 SMAD9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 16189514 10583507 25502805 25609649 31932471 15231748
SMAD6 SMAD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11483516 12857866 9436979 9256479
SRPK1 RBM39 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 28302793 23602568
RBM39 SAP18 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 25416956 16051665 22365833 33961781 28302793
CDKN2A NPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
FMR1 FXR2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
TNF TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
SMAD4 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15886208 16603637 18620728
BBC3 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15574335
MYC BCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SIN3A BCL6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16147992 9765306 9753732
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
CCND1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16061635 9039267 11073968
SOX2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18456656 25482558
YBX3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16508013 20133805 19730435
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
ZBTB33 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
GATA3 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
LHX2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19340300
PAX6 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20053773 11584062 17157287
SRPK2 DDX21 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26167880 33961781 23602568
DDX5 EP300 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 33742100 12527917
DDX5 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 20308691 11250900 21182205 10409727
EP300 DDX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12527917 20663877
EP300 TAL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11756538 11118214 10490830
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
EP300 KPNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10801418 15342649
USF1 FMR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15175277 18782566 11058604
MDC1 H2AX â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21622030 16377563 19234442 28242625 32518374 20159462 21676867 12475977 14519663 15201865 12607005 21293379 30598506 18001825 29499138 26734725 18001824 18583988
MEN1 SMAD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22275377 11274402 15150273
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
SMAD1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 15576399 22290435 22761862
WT1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15286719 17634147 20842112
MYC RPL13A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
MYC APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC YBX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12080043 18414489
MYC FXN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RPS6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RBM39 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RRP1B PARP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 34079125 20926688 19710015
PARP1 KDM5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20832725 33859667
RAD21 SMC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15855230 17112726 21111234 17349791 26496610 10931856 21043528 17113138 18235444 22885700 22939629 31010829 21880767 22145905 33961781 24981860 15737063 16802858 20818333 26344197
RAD21 SMC1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19308699 17112726 31807710 26496610 10931856 21043528 17113138 11590136 22885700 22939629 31010829 22145905 23242214 33961781 24981860 15737063 20818333 26344197
CTCF RAD21 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19369356 19826084
YBX1 SMAD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12917425 12446674 16278212
YBX1 SMAD4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12917425 12446674 16278212
AKT1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 23397142
SMAD1 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 17183365 16189514 32296183 31467278 12167862 14701756 12874272 28468752 15761153 24412244 10531362 15231748 11700304 11779505 26555259 9436979 21454478
SMAD3 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 16189514 25514493 11927552 28443643 21988832 20211142 15084259 12732634 19768112 15467747 20142324 25609649 15922743 12917407 12419246 20564330 24382352 19139564 32296183 24157709 18729074 22442258 10092624 17283070 15350224 17591701 15761153 31591477 10995777 26555259 9892009 9311995 15588252 12167862 10878024 25910212 27703004 33990575 28115363 18055455 22310290 19135894 10531362 12794086 15231748 21297662 22045334 19917253 24584437 27107012 29892012 29997244 21532621 27845895 21597466 25502805 11114293 12543979 23788427
SMAD4 CTCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12099698
LTA TRAF2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 8663299 9122217 12571250
AKT1 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16362038 25241761
SMAD6 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9892110
KLF16 SIN3A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12036432 11438660 22203677 35140242
AURKB H1-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21511733
POU5F1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23041284 20683952
CTCF APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11706010 10582586 9407128
RBM39 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21182205 33731348 11704680 15694343
ESR1 DDX17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 11250900 21182205 20348541
ESR1 H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19515975 23108396 20023423
ESR1 RPS6KB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22286763 21292829 18414489
RXRA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
ESR1 RXRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9841885 9717844
EZH2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21135039 21884980 27338022 18931660 28068325 23079660 24469040 19026780 21190999 26496610 26748827 24320048 33849069 35016035 27634302 29669287 18285464 20543829 18453536 31130994 21123648 20123894 24183680 27728805 25470042 12435631 22939629 16224021 23624935 24457600 26344197 20075857 15882624 23684459 31786184 31281901 23238014 26130719 19026781 27705803 22439931 27303043 31631027 24981860 33961781 19734898 31948940 18483221 21378168
RBM39 SRPK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26167880 25416956 22365833 28302793 33961781 23602568 32707033
EPAS1 POU5F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20139178 19755485 16510872
KDM5B H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30246379 17909537
WT1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7559553
CTCF SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18662993 21536749 33196849
HDLBP CTCF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 31917284 24725430
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
AURKAIP1 MRPS5 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
ACIN1 SAP18 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
RPS6KB1 RPS6 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 15809305
TOP2B TOP2A â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 8710863 22939629
MRPS22 PTCD3 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
MRPS22 MRPS5 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
SMAD4 SMAD9 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
DDX17 DDX5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22365833 15298701 19995069 22863883 33961781 24581491 10837141 22939629
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
POLR2A SMARCA4 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
MRPL11 MRPS5 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
FXR2 FMR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 25416956 16713569 7489725 26949739 21653829 8668200 24778252 10567518 30217970 33961781 24981860 24722188 29395067
H2AX MDC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6805208 18583988
SMC3 SMC1A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17112726 21111234 31807710 17349791 26496610 10931856 17113138 18832153 11590136 12759374 30021884 22885700 22939629 9789013 31010829 21880767 11877376 23242214 24981860 27173435 11076961 26344197
MRPS5 PTCD3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CCND1 CDKN1B â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
FBL NOP56 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
POU5F1 SOX2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RPL10A RPL13A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL31 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RAD21 SMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC1A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPL18A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPL14 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL18A RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL14 RPL5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL5 RPL7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL18A RPL7 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL7 RPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL10A RPL5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL5 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL18A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL18A RPL31 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL31 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL10A RPL14 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL31 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL14 RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL31 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL31 RPL7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL31 RPL5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL10A RPL18A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BAX TRAF2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
BAX TRAF2 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
BAX TRAF2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
MYC BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8845569 11103792 12695333
AKT1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26763134 14766748 15642728 17525161
MYC BBC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12695333 12384701 19815507 20145032 21835778
BCL3 TNF â—¼   DOWN_REGULATES ✅ - 21.0 1.0 ACSN 10754326 10952726 11875494 12907458 14660645 14668329 15079071 15465827 15536066 15644117 16878026 17145890 17404308 17485448 19171876 20138012 23390297 23430059 7594497 8383323 8580069
BCL3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24189068 11713278 12808109 20731879 20420878
BCL3 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12907458 15465827 22782967 22798670 24130828
MYC CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7526316 21933022 17881732 12835716 14757441 19086036 8552398 19698176 19786833 18809243 18806825 8196642 11085504
ESR1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11477579 12554765 12808053 17166846 22892083 21505052 18414489 9832502 23864650 22396492 22266855 11358796 23891847 22948256 11986316 15282324 15496458 22521644 14764652 15178330 23108396 11410592 15026472 17998543 17681750 18245487 20821348 16860316 11844790 19858209 12929585 15808510 18997820 15217513 16809759 10500157 16980581 17914104
EP300 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17306568 17666529 11788592 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
CDKN1B CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17145710 9106657 10908655 17254966 25416956 7478582
ESR1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8649771 11073968 16061635 9039267
KLF8 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
MYC CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
CCND1 RBL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16600870 10498883 10385618 9736735 12006580
AKT1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 22119715 11756412 16780593 11923280 16697215 16209941 12244303 20398329 18372248 14967450 18710949 15808505 26053093 20138985 14504289 20214616 12244302 17570479 18593906 23576547 23400686 12851486 15169778 24651496 19829074 25241761 10949026 16288292 11715018 18636226 19377290 9812896 12042314 17680028 10722653 20832730 18570873 12244301 17052453
EP300 CDKN2A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 32284348 19273602 32601262 10821856 28985506 33043019 31597407
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
RUNX1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12732181 18276842 21757616 10851069 12091906 23673926
EZH2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19954516 21572997 23289480 23826727
CTCF CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22025288 12524457 19340300
NPM1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16957780 20208519 15289458 16199867 16915296
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
PARP1 CHD1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22146311 19666485
DDX5 GATA3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17495528 15343269 19718048 11682626 28539435 14675539
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12419246 14500836 10673036 22298955
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
HMOX1 TNF â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17689680 22461508 23390297 6357187 8871614
MYC HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12695333 10600159
USF1 HMOX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 7969144 8760880 18331200 15242350 2318208 2722866
AKT1 HMOX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15581622
H2AX MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21676867 14519663 18001824 21293379 16427009 16377563 18583988 21622030 18001825 12607005 19234442 20159462 15201865
KLF8 MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 11955436 11967263 12051714 15001769 15576399 16039586 17143292 17306568 17666529 17671186 17936032 19619488 19623618 20705860 21151179 21285352 22290435 22761862 23343194 24023259 25730849 7542250 8666229
MYC VEGFA â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 20940401
MYC H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18414489 22055461 12695333 11085504
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC HBA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 2463629 12695333
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 1904416 12695333 24725430
MYC NCL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10606642 24951594 12695333 14519204 25018006 11983916
MYC VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19738061 19147754 17785433 22002305 18809243 19398483 12368264 23028984
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
AURKB RASSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19887622 19276349
RASSF1 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 14743218 19276349
SMARCA4 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9099865 18451880 11003650
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDC20 SMC3 â—¼   UP_REGULATES ✅ 8.0 1.0 ACSN 12070128 15279786 17303408 17660363 18590585 21270334 23197039 7575488
TRAF2 TNF â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNF â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNF â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
ESR1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23733894 15334655 16483936 12237295 20664923
AKT1 YBX1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17081983 32028981 33911076 26318844 33151228 20844753 27591085 17704806 21423216 19036157 31906126 15806160 24335958 34272387 33379356 19651622 31387591 16354698 19664994
GATA3 YY1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763
AURKB YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23226345
PAX6 CRYAA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7753864 15558475 21092858 15161860 16675956 16023139
VEGFA SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
VEGFA SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
IRAK2 VEGFA â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
VEGFA SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
SMAD4 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23184087 10944227 20797318 12622415 24625091 20631490 18505344
ESR1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16267616 12400015 17272396 18252963 18497067 10866309 19420388 19398483 16249470 14647449 15774498 12208749 10995484
SMAD3 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15188178 18952601 20631490 22740248 21057546 15629128 11486006 15191565
EPAS1 VEGFA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15156561 15192019 19010893 15191799 19080330 20061373 9113979 16900513 20574527 10531360 21057546 21145972 11350893 16778202 23213445 11301389 20807755 9746763 9665461 11751212 12750296 24062466 11912213 16920734 17322369
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   PROTEIN_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20957627 23331499 14534577 16516194 16189514 10531362 15231748
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMAD9 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20957627 25502805 10583507 31515488 16189514 15231748
AKT1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 25241761 15104092 16362038 21071413 18988627 26297431 15048128
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
AURKB CDC20 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
GRB10 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11809791 15722337
AKT1 SRPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19592491
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
AKT1 TAL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19406989 15930267
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 ILF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20870937 18097023
AKT1 CDKN1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12925736 23421998
AKT1 POU5F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23041284 24497960
AKT1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11943559 23331499 25241761 21071413 12183455 15149849 11438723
SMAD1 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10692396 17215250 22219353 22072987
SMAD6 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9256479 9335505 9436979 21071413 18988627 11483516 12857866
CTCF CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19129223 22422629
RPS6KB1 RPS6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 17053147 17081983 33676898 19339977 92042229 20484036 16286006 20647036 11438723 17360704 1737763 17121928 11108711 20227368 22408430 27312851 12668683 16083285 15051500 20146692 15471950 18423201 17570479 20039704 21460850 21602892 1985906 30034573 21233202 24662264 29892299 19720745 12586835 12713446 20464435 26824026 15809305 16810323 86287375 24396066 24578720 20616057 24205356 19203585 15905173 14993219 17726024 20832730 22530122 17052453 7705100 15358595
GATA3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17616709 20130088 20068169
RPS6KB1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 29128895 23242584 22114931 23460185 19925796 19112174 7838153
DDX17 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19995069 21182205 12738788 20348541 19718048 20663877 25604459
ESR1 GATA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26153859 25303530 10096242
USF1 HBB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16943425 12000849 17970752 19704006 19491096
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462
SRPK2 ACIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21056976 23602568 18559500 22365833 17287340 19592491
H3C2 AGO2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16936726 22722852 25313066 16373483 21589992 24086155 17085592 22445173 18227514 18852463 21427083 22961379 24388755 22064859
POU5F1 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20505756 12136102 17324942 15988017 17068183
EGLN2 EPAS1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 12615973 18184961 12788921 19208626
SMAD5 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10692396 16436528 22219353
PAX6 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19666824 17825048 11358870
MYB LYZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7684005 11716756 20524209 17959653 17950008
GATA3 H3C2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 18533032 27062924 21151129 16009131 16087863 16980581 21934649 16113099 18358809 22056668 23172872 15282324 21878914 23192763