Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
ATM DYRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19965871
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
TP53 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 ATR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 9925639 10435622
HDAC3 BCL11B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219549 17245431
HDAC2 BCL11B â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
BCL11B HDAC1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219549 17245431
NF2 COPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC COPS5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7229502 19214193
COPS7B NEDD8 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CUL4B GPS1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
FOXM1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346 17875680
ESR1 TMPRSS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19013008 18414489
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
FOXM1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16809346
ESR1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24641954 20623181
PPP2R1B HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
RCHY1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16914734
HDAC3 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16847267 0510834103
HDAC8 TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220135 17721440
HDAC8 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 26387755 17721440
TP53 MYO6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16507995 20576604
RBX1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15572695 19560419
TP53 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
UBC RCHY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220017 17568776
RCHY1 TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 5220017 17568776
TOPBP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18923429 7296625
WWP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
COPS8 NEDD8 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
COPS4 CUL4B â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
RBX1 UBC â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
HIST1H3A HIST3H3 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
ATM EXO1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 20019063
DDB1 MUS81 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 27354282 24412650
DDB1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24249678 26679995 25189618 34026424
VPRBP UNG â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20870715 22292079 21226479
SAMHD1 VPRBP â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
UBXN7 CUL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
CUL1 DDB1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22474075 21145461
UBXN7 CUL4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
CUL4A MERL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18332868 20178741
CSN5 DDA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19295130 21145461
VTNC VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN7A RBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19295130 26496610
DDA1 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19295130 26496610
NEDD8 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
NEDD8 RL6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18274552 21145461
RL6 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ZN263 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RL15 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AKIP VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RL7 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RL18 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IFIX CTCF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28077445 25665578
L2GL2 DDA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
T53G5 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RM35 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NOL9 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UBXN7 RBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22537386 18775313
SOX2 UBR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30894683 23667531
SOX2 VPRBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26186194 23667531
COPS7B RBX1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
COPS8 RBX1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
CUL4A PWP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21145461 33355139 17079684 19295130 31973889
CCNL2 MERL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CSN5 RBX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19295130 18850735 30349055
VPRBP CSN7A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18606781 19295130 26496610
RL15 RL6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22939629 24981860 26344197
RL14 RL6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22939629 26344197
VPRBP CSN8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 17609381 33355139
RL14 RL18 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22939629 26344197
RL14 VPRBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RL14 RL15 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22939629 26344197 26186194
ZC3H1 VPRBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
IFIX VPRBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25665578 26186194 28514442 28077445
L2GL2 VPRBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
COPS5 VPRBP â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
UBXN7 CUL4B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22466964 31973889 18775313
VPRBP NEDD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33355139 17609381 21145461
COPS2 GPS1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
COPS2 RBX1 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
DYRK2 VPRBP â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDB1 SIRT7 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDB1 HIST1H3A â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
COPS6 DDB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
COPS6 CUL1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
COPS4 COPS5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
COPS4 DDB1 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
VPRBP CUL4A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17609381 30166453 21145461 30590706 25532805 33355139 20870715 18606781 17630831 16949367 17079684 19295130 31973889
DDB1 CSN6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16964240 21145461 22767593 16949367 19295130
GPS1 COPS8 â—¼   COLOCALIZATION ✅ 0.85 0.85 mint 24421388
CUL4B HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25189618 34026424
CUL4B HDAC2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34026424 25189618 30737378
UBXN7 NEDD8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 22466964 24076655 22537386
COPS3 NEDD8 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
COPS4 NEDD8 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST1H3A â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
H3F3A HIST3H3 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
COPS4 COPS6 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CUL4B DDA1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
DDB1 CSN5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16964240 21145461 22767593 16949367 23357576 19295130 18850735
RL15 CSN6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16169070 21145461
CUL4B RL14 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28225217 21145461
ATM PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10464290 10608806
GPS1 COPS6 â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 24421388
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
HDAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16469706 26487511 14722073 31527615 20348541
SOX2 PWP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
COPS3 RBX1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
COPS4 CUL4A â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CUL4A DDA1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CUL4A CUL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17079684 32235678 21145461
CUL4A CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16964240 21145461 26496610 18606781 17079684 19295130 31973889
CUL4A CSN8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27173435 16964240 21145461 18606781 17079684 28514442 19295130 31973889
MERL DDB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18332868 33058421 20178741 26549023
CUL4B CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 26496610 19295130 31973889
CUL4B CSN8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27173435 24981860 21145461 26496610 28514442 31973889
SOX2 HDAC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 21532573
NR2C2 HDAC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21670149 12943985
RCHY1 UBE2D2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ATR TP53 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
DDA1 VPRBP â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CUL1 UBE2D2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
COPS3 GPS1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
NF2 VPRBP â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CSN7A CUL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29103612 19141280 21145461 12628923 27833851
COPS7B CUL4A â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RL15 PWP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442
COPS6 COPS3 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24421388
DDA1 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21145461 26496610 16949367 19295130 31973889
VPRBP CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21145461 22038470 26496610 33355139 16949367 28416635 31973889
DDB1 DDA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17609381 16964240 20562859 26344197 16949367 17452440 19295130
COPS7A CUL4A â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COPS2 NEDD8 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COPS5 DDB1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
PRKDC TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
COPS3 CUL4A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPS3 CUL4B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPS3 DDB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
COPS8 CUL4A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
RCHY1 TP53 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CUL1 CSN8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19141280 29103612 21145461 18173839 22959436
DVL2 WWP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26701932 31340145 34139860
CSN5 CUL4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12732143 26976604 33961781 16964240 21145461 19615732 32047038 27029275 25349427 18606781 23357576 17079684 26186194 22956996 28514442 19295130 18850735 22474075
CSN6 CUL4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16964240 21145461 19615732 18606781 26186194 17079684 30945288 28514442 19295130 33179082 31973889 22474075
CSN5 CUL4B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 34026424 23238014 19615732 21145461 26496610 23357576 26186194 30945288 28514442 19295130 18850735 31973889
CSN5 VPRBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 33355139 18606781 19295130 18850735
CSN5 NEDD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 25144743 19615732 21145461 16503656
CSN6 VPRBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 33355139 18606781 19295130
CSN6 DDA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 19295130 33961781 21145461
CSN6 NEDD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 25144743 19615732 21145461 16503656
SAMH1 VPRBP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22362772 23677995 24336198
TP53 RCHY1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 17568776 5220017
TP53 RCHY1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 17568776 5220017
UBC UBE2D3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
UBE2D2 UBR5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
COPS8 CUL4B â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
DDB1 UNG â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
NEDD8 RBX1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
NEDD8 UBE2D2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
COPS2 CUL4A â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CSN6 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19141280 29103612 21145461 19615732 34237211 11337588 19295130 22474075
CSN5 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34237211 21903097 26265931 29103612 21249194 27774986 25144743 19615732 22767593 24973710 22959436 22956996 18850735 31950832 19141280 21145461 22013077 29863914 22474075 16036220
MERL VPRBP â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18332868 21750658 24912773 26549023 33058421 20178741 28514442
CSN7A CSN5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22939629 26496610 17429597 22863883 19656241 26344197 12628923 20399188 19295130 19615732 27833851 28514442 18850735 11285227 31950832 21145461 11337588 10903862 26186194 17403899
CSN8 CSN7A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 11285227 9707402 26344197 27833851 26496610 11337588 10903862 22863883 23213463 28514442 19295130 17403899
CSN6 CSN7A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 19141280 26344197 21145461 19615732 27833851 26496610 10903862 22863883 26186194 23086934 28514442 19295130 17403899
CSN6 CUL4B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21145461 19615732 26496610 22863883 26186194 28514442 19295130 31973889
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
COPS2 CUL4B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CTCF NFE2L2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
CTCF MCM10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
CTCF KSR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
RBX1 CUL4B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 28446751 34026424 29499938 22038470 19250909 26496610 31973889 12481031 30349055 24292684 30945288 33969670 27113764 32140073 33504946 12609982 25189618 23238014
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
ESR1 PWP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
CUL4A VPRBP â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
COPS6 RBX1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
COPS2 CUL1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
DDB1 GPS1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CUL4A GPS1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
COPS5 CUL4A â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
CUL1 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
NEDD8 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
GPS1 COPS5 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 7228517 19444310
GPS1 COPS5 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 24421388
COPS4 RBX1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS6 NEDD8 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
UNG VPRBP â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
COPS5 RBX1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
UBC UBR5 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
GPS1 NEDD8 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
RAG2 RAG1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9630231 14670978 26124138 9036966 8777717 12861017 25745109
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
CUL1 GPS1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
GPS1 RBX1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
MYO6 UBC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 16177058 18723677 18627766 17438373 32726803 24654937 11027288 18274552 10772955 16503656 24076655 18247557 22405651 17318178 10713156 19713960 10318914 21102408 23267066 23201271 22959436 17206147 16620772 18805092 10597293 21119685 21145461 18826954 19245792 19617556 12565873 18264111 24949976 22474075
CSN8 CSN5 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 31950832 9707402 21145461 19615732 11337588 20399188 26186194 28514442 19295130 18850735 23636414
CSN8 CSN6 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 9707402 26344197 21145461 19615732 22939629 11337588 22863883 26186194 32034103 28514442 19295130
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 21670149 24981860 22939629 26496610 11102443 11919195 11777905 30737378 9885572 22416134 26344197 21258344 9804427 12493763 11287668 16713569 11466315 12920132 20388487 9790534 10581039 11739383 15987735 17894944 19182791 9150135 28514442 26949739 19041848 10444591 19703393 11804585 25241761 17956988 11564889 12032298 15451426 15297431 23752268 18059533 9520398
UBC UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
DDB1 RBX1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
COPS7B COPS8 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CUL4B RBX1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
COPS6 GPS1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RBX1 UBE2D2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
COPS7A COPS8 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
CUL4A RBX1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
COPS2 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
COPS6 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
DDB1 VPRBP â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
CSN6 CSN5 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 32034103 22863883 26344197 20399188 19295130 12220626 25144743 19615732 28514442 18850735 25043011 11285227 27173435 19141280 31950832 21145461 11337588 26186194 21625211
COPS5 COPS7A â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
DDA1 DDB1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1A PPP2R1B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RAG1 RAG2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
COPS3 COPS7B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS7B GPS1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS2 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS4 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS4 COPS7A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS5 COPS8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS6 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RBX1 UBE2D3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS2 COPS7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS3 COPS7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS3 COPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS4 COPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS7A GPS1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS8 GPS1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL4B DDB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS2 COPS5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 GPS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS4 GPS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS5 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS6 COPS7A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS2 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 COPS3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 COPS4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS2 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS3 COPS5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS3 COPS4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS4 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS5 COPS7B â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS5 GPS1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS4 COPS5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CUL1 RBX1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
DYRK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 29296831 21383696 14749479 11740489 20171273 25778922 15843377 33906076 10581258 15750624 15897882 15706352 26236013 24899407 33572115 17906639 20935676 24379358 17386256 15870257 26346493 12427754 34103685 17567906 11101524 17210684 18536714 15381073 19965871 26578795 26087959 28060750 21765464 20673369 34216619 16601678 17380123 33443163 18216278 21642861 15526030 22878263 17349959 16738336 20696760 19882354 16219768 17105820 16793543 17332358 24901999 16247456 24196445 26804244 15657359 27208501 18056705 21765463 23420876 22797063 16377624 19861417 18160537 12676607 20123963 15489221 17591690 20514025 23149944 19857493 17891183 27034505 11780126 21057547 25944899 26341817 17349958 20962272 22525275 19828042 12902982 19465479 15471885 15322239 11495913 12907596 32083004 25915850 20018442 24145406 26029824 21394211 12093737 33872315 20610713 20024960 26113041 20811699 18560558 21660965 16717128 11030628 17107963
DYRK2 KATNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19287380
RBX1 CUL1 â—¼   PHYSICAL_INTERACTION 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   SHARES_COMPLEX 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 76.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 14536078 15001769 15071497 15147722 15340381 15459660 15489953 15688063 1570337 15703371 16039586 16469695 16697054 16713974 16940750 17053147 17143292 17652783 17884153 17928543 17936032 18196958 18636226 18787170 18805092 18931676 19143635 19150432 19250909 19258535 19270156 19352404 19366350 19411070 19557001 19576224 19597341 19619488 19622404 19686080 19751508 19797085 19809470 19836308 19847258 19849719 20006983 20211143 20558317 20705860 20832730 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26159692 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 154.0 1.0 Omnipath 17053147 12684064 20638939 11967263 19797085 19258535 26540345 18826954 15071497 15448697 21765416 25730849 10230406 23343194 21169563 22270359 19250909 23732914 11359933 12051714 20006983 15361859 10748083 19352404 22682247 18787170 12504025 18636226 16469695 15459660 20211143 10535940 15001769 26725323 19411070 11861641 26159692 16697054 1570337 19751508 22822056 11348595 7542250 7641885 19849719 16759355 12820959 17452440 19622404 15703371 10648623 19245792 23331499 9694792 19150432 23180781 19597341 16189514 22474075 18988627 22767593 17143292 24949976 10713156 23770852 22405651 19942853 18196958 20399188 16713974 26192618 11027288 17884153 19933270 22730322 21411632 11961546 17936032 19809470 15147722 19270156 19576224 11483504 20976471 12504026 24023259 12840033 15340381 12904573 20558317 11900249 14536078 19686080 12565873 18805092 15489953 19557001 26885856 17652783 12481031 20843316 11955436 21071413 16039586 11956208 20705860 8666229 17928543 10023660 19836308 16940750 12706828 19143635 15688063 10671552 16123592 19366350 19847258 12417738 11245432 20832730 12648680 12609982 19619488 10230407 18931676
RBX1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
RBX1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
CUL4A COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
ATM EXO1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
ATM TOPBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11756551 18077418 19279141 17525332 17446169
ATM PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23042680 23449221 24000320 21824916 23433795 17525332
ATM EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 15964794 11877377 17303408 18756267 16163361 15867354 23847781 23675572 25956864 26240375 11438669 24705021 12607003 18048416 17525332 20019063 15459660
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATR TOPBP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
ATR TOPBP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11877377 12766152 15459660 15485915 15798197 16530042 16880517 16885023 16934469 17102137 17116885 17296725 17303408 17384638 17582221 18677104 19282663 19622404 19793801
ATR EXO1 â—¼   ENZYMATIC_REACTION ✅ 42.0 1.0 ACSN 11438669 11877377 14988723 15136767 15459660 15485915 15798197 15867354 16332722 16540648 16713580 16731533 16885023 17102137 17116885 17296725 17303408 17384638 17582221 18048416 18511906 18543256 18677104 18716619 18756267 18931676 18995830 19004803 19282663 19357644 19490890 19622404 19686080 19772495 19788416 19793801 19793861 19841479 20019063 20051983 9488723 9858600
TOPBP1 ATR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16530042 18769153 16285702 18066086
ATR TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 106.0 1.0 Omnipath 17145710 22778941 24395704 28468838 12401524 15159397 24877058 15254178 9733515 11483158 15806145 19056039 11875057 15865930 11551930 11883897 19923893 12548019 18697815 29170437 16293623 19010925 11709713 10446957 9363941 21748595 17272272 22797063 12242661 10196661 22084686 10747897 10608806 10673501 12091386 17118344 23892398 9765199 15489221 24037342 15140942 10435622 17241873 10597277 10801407 11711532 17174997 21593792 25201202 9843217 10606744 15024084 15226429 15922368 21415014 21480565 15585169 24947324 9925639 23380594 9733514 11865061 19625493 16390936 10951572 10570149 23311997 12111733 26144601
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
ATR EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 18677104 19622404 15798197 19793801 11438669 18756267 19282663 17116885 17582221 17384638 17525332 20019063 15459660 17296725 11877377 15867354 17102137 24705021 18048416
DDB1 COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
RBX1 COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
CTCF TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 17267411 19806612 1632686 16326864 24174344 19914212
RBX1 DDB1 â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
RBX1 DDB1 â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18381890 18931676 19270156 19440234 19557001 19622404 19686080 19809470 19847258 20211143 20457011 22257761 22373527 22615860 22824526 23085398
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21411498 12122114 21693539 18519947 16690106 10805720 19360348 23409030 18754863
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
NR2C2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 11844790 10611280
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
HDAC3 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC3 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
RBX1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
RBX1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
UBXN7 NFE2L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
RBX1 NFE2L2 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 16790436 32284348 24366543 15601839 19321346 17081101 23986495 15367669 15572695 9887101 17785452 15282312
RBX1 NFE2L2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
PRKDC PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23433795 21824916 24000320
PRKDC TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 79.0 1.0 Omnipath 15355354 19398950 15254178 9372954 11483158 7862459 16713569 11875057 11551930 11883897 12548019 25168287 8502477 11709713 10446957 28145533 22726545 24886358 16552184 12242661 17570479 10196661 10747897 9885574 10673501 12091386 22355272 9765199 15489221 9561848 10801407 22504299 22444248 15177184 11042698 10358069 10470151 10606744 9744860 16397295 12959929 12064478 27130668 10951572 12111733 25937999 15381073 28102346 9363941 19918261
RAG2 RAG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12861017 9036966 14670978
RAG1 RAG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12861017 9036966 14670978
UBE2D2 RBX1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D3 RBX1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
RCHY1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 21988832 19483087 17568776 24367557 25116336 21084285 12654245 21791603 20452352 19043414 16713569 31630802 27519799 19918835
TP53 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15656906 12807729 15067344 15734740 11064449 15262117 16234237 10778946 15371422 22496369 18754863 19649288 19787269
PRKDC ATM â—¼   KO_DOWN_REGULATES ✅ - -1.5 1.49 PKG 28854368
EXO1 MRFAP1 â—¼   KO_UP_REGULATES ✅ + 1.88 1.88 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
UNG UNG â—¼   KO_DOWN_REGULATES ✅ - -5.41 5.4 PKG 28854368