Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PCNA UNG â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TP53 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7915517
GSK3A UNG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 27875297
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
SP1 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18208837 7534297
APP HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12392301 22242153
TP53 PMAIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10807576
TP53 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11807984 16567167
TP53 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18980971 16636674
UNG APOL2 â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
VPRBP UNG â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20870715 22292079 21226479
KCC2D UNG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
UNG PURA â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
HSPB1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
UNG EPHA1 â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
PCNA APEX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10559261 11601988 16189514
UNG FOXH1 â—¼   KO_DOWN_REGULATES ✅ - -0.87 0.86 PKG 28854368
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
POLB CRIPT â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
DDB1 UNG â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
PMAIP1 GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B UNG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17570479 27875297
UNG RFA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10982866 10393198 24910198 24332808 9045683 16189514
TP53 APEX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18208837
TP53 DDB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16357511 19382146
POLB MT1E â—¼   KO_UP_REGULATES ✅ + 0.9 0.9 PKG 28854368
UNG SLC20A1 â—¼   KO_DOWN_REGULATES ✅ - -0.93 0.92 PKG 28854368
UNG VPRBP â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
UNG ALKBH1 â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UNG MT1E â—¼   KO_DOWN_REGULATES ✅ - -0.95 0.94 PKG 28854368
RPA2 UNG â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
UNG SARAF â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
DDB1 VPRBP â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
UNG MT1G â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
PCNA POLB â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 16442856 16697054 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
POLB RPA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
POLB PCNA â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
PCNA POLB â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 16442856 16697054 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
RPA2 PCNA â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
RPA2 PCNA â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
TP53 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10321841 7915517 15358233 12217864 10516009 1705714 8570655 16980608 9707425 15950182 19789303 11313928 1356162 12384701 9858527 12947108 23390122 8524244 9651310 1352831 7909518 11032828 10910968 12485898 10618724
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
UNG APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9724657 15479784 25086253 9200707
RPA2 APEX1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11687589 9214649 11601988 10744741
APEX1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18786561 19180539 9119221 19737086 16713569
TFAP2A APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17651731 9048735
SP1 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19049493 8427604 15673661 9361293 21557719 18449948 14701757 8015372
RPA2 DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
SP1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9328340 8923463
HSPB1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19656944
HSPB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25241761 16169070 16713569 17184779
SP1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9348238 17446237 23626778 18664368 14744869 15001547 23027183 14998783 17449871 15330762 19485892
TP53 PMAIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 10807576 23959540 15580300 19797274 15856024 20591651 22216287 14695212 14500851 20195489 21969549 18042711 20160496 15598651
TP53 PPM1D â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18333294 19015127 11101524 22405851 20093361
PPM1D UNG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15327777 15870257 16189514
PPM1D TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15870257 17936559 23666059 28903382
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
SP1 SPP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24240095 11126367 17689681
UNG SPP1 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
UNG INS â—¼   KO_DOWN_REGULATES ✅ - -1.13 1.12 PKG 28854368
UNG CRIPT â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
POLB EPHA1 â—¼   KO_UP_REGULATES ✅ + 1.15 1.15 PKG 28854368
UNG MT1X â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
UNG NEU1 â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
UNG AMIGO3 â—¼   KO_DOWN_REGULATES ✅ - -1.18 1.17 PKG 28854368
UNG PMAIP1 â—¼   KO_DOWN_REGULATES ✅ - -1.2 1.19 PKG 28854368
TP53 INS â—¼   KO_DOWN_REGULATES ✅ - -1.53 1.52 PKG 28854368
POLB MT1G â—¼   KO_UP_REGULATES ✅ + 1.52 1.52 PKG 28854368
POLB SPP1 â—¼   KO_UP_REGULATES ✅ + 2.17 2.17 PKG 28854368
UNG UNG â—¼   KO_DOWN_REGULATES ✅ - -5.41 5.4 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368