Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
POLB WFS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 CRIPT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRIPT UBQLN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATM CRIPT â—¼   KO_DOWN_REGULATES ✅ - -0.81 0.8 PKG 28854368
PARP2 CRIPT â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
CRIPT DLG4 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
RAD52 CRIPT â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
POLB CRIPT â—¼   KO_UP_REGULATES ✅ + 0.87 0.87 PKG 28854368
CRIPT DLG1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12070168 24550280 16713569 18951956
MYC POLB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CRIPT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
NHEJ1 CRIPT â—¼   KO_UP_REGULATES ✅ + 0.91 0.91 PKG 28854368
DLG1 DLG3 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 26496610 12351654
DLG4 DLG3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10026200 28973854
CRIPT DLG3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12070168 11937501 16713569
DLG4 CRIPT â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9581762 20018661 16713569 11744724 11937501
PARP2 POLB â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
PARP2 POLB â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
ATM PARP2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM UBQLN4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30612738 17525332
MYC CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8386381 10713672 12835716 7608142 12937171 14519204 14729654
UNG CRIPT â—¼   KO_DOWN_REGULATES ✅ - -1.15 1.14 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
UNG UNG â—¼   KO_DOWN_REGULATES ✅ - -5.41 5.4 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368