PKG

Protein list:

DLG1 CTNNB1 CDH1 MARCHF2 CTNND1 PTPRE CDK2 CDK1 EPB41 MAP2K2 ADAM17 CAMK2A CLDN4 VANGL1 ZMYM1 AKAP5 TMEM178A MTMR1 DLG4 RALBP1 GRIN2B ANO9 DEFB116 PABPN1 CRHR1 TPBGL CALHM3 GRIN2A HTR2C SEC14L3 MAS1 ADGRA2 CACNG2 MARCHF3 KCNJ2 SSBP2 ADAM10 KCNJ12 MCC SLC16A3 CTNND2 HEATR5B ADGRA3 RAPSN ADAM22 AMOT MAPK12 ATP2B4 GRIN1 NEFL GRIN2D IQSEC2 SLC1A1 EVI5 AXIN1 ATP2B2 CD1D ACTN2 ARHGEF16 AXL RPS6KA2 APBA1 LIN7A PRNP KCNJ18 ANO2 ARHGEF26 TUBA1A GUCY1A2 CYSLTR2 CTNNA1 GRIN2C ESR1 PIK3CA ADGRA1 TANC1 FAM163B LRRC3C NET1 CALM1 MRPS34 BAI1 VANGL2 TBX15 FAM163A BTRC ADRA1D NRCAM IQSEC1 DCUN1D1 RHOD PLAC8L1 KCNC1 RLIM SCN5A MARCH2 NXPE2 HTR2A CAMK2G GJB1 PBK KHDRBS1 TGFA RHOQ MAP1A TJAP1 SSTR1 SLCO1C1 PKP4 MYO6 ZRANB1 FRMPD4 E6 RHOC UBE3A EZR RAC2 PIK3R1 RHOG KIF13B PIK3R2 LRRC7 ZSCAN30 LRFN4 CAMK2D EXOC4 LRFN2 LRFN1 KCNJ6 GPR124 PRR5 CAMK2B LRRC1 CASK CADM1 ADRB1 MPP3 LIN7C MPP7 PRKAR2A KRAS SRC HRAS NRAS SNAI1 HSF1 NTRK3 PRKN TMEM17 LCK EPHA4 TGOLN2 EPHA5 LAMP1 EPHA7 GRIK1 KCNJ4 KCNA5 RASGRF2 HNRNPU MAP3K3 RASGRF1 EFNB3 RHOB ARHGG RASK CCG2 ADA10 GRIK2 MPP2 GRIA1 GP125 DLG2 MK12 ERBB4 DLGAP1 PTEN DLGP4 APC CLTR2 RBP1 EZRI KCNA3 ADA17 KCNA4 GCYA2 CRIPT ARHG8 GP124 ASAP1 YY1 AT2B4 DLG3 IRK2 IRK4 NMDE2 NMDE1 IRK12 DLGP1 CSKP KIF1B

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

PKG Score Threshold: 0.8

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Filter Table:

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Source	Target	Relationship Type	Directed	Sign	DB Score	PKG Score	Database	References
ACTN2	RASGRF1	◼ PHYSICAL_INTERACTION			2.0	0.8	Reactome	14622581 10373510
ADA10	DLG1	◼ PHYSICAL_INTERACTION			0.83	0.83	HIPPIE	25036101 17301176
ADA10	LCK	◼ PHYSICAL_INTERACTION			0.88	0.88	HIPPIE	11741929 25036101
ADA17	DLG1	◼ PHYSICAL_INTERACTION			0.89	0.89	HIPPIE	12668732 18930083
ADAM10	CDH1	◼ CLEAVAGE	✅		2.0	0.8	Reactome	18434311 15958533
ADAM10	ADAM17	◼ PHYSICAL_INTERACTION			5.0	1.0	ACSN	18676862 19601831 19704010 19726682 22006996
ADAM17	SRC	◼ PHYSICAL_INTERACTION			2.0	0.8	intact	0509719103 16641105
ADAM17	TGFA	◼ POST_TRANSLATIONAL_REGULATION	✅	+	2.0	0.8	Omnipath	26284334 11823465
ADAM17	ERBB4	◼ POST_TRANSLATIONAL_REGULATION	✅	+	8.0	1.0	Omnipath	15534001 15746097 10744726 9685416 26554003 17486069
AKAP5	CALM1	◼ PHYSICAL_INTERACTION			850.0	0.85	STRING	36370105

Showing 1 to 10 of 386 entries