SHANK1
|
ADGRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10964907
5212940
|
DLG4
|
ADGRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SRC
|
SPRR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7216055
18155796
|
SPRR2A
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7216055
18155796
|
CALM2
|
CALM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
CALM1
|
CALM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
CALM3
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
CALM3
|
RASGRF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7637786
8756648
|
DLG4
|
VMAC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
CALM1
|
CALM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
CALM2
|
RASGRF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7637786
8756648
|
CALM2
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
SHANK3
|
NEFL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
RASGRF2
|
NEFL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
NEFL
|
RASGRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
GRB2
|
SHANK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SHANK3
|
DLGAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
DLGAP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
SYNGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
LZTS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
DBNL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
DLGAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SHANK3
|
SHANK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
TRIM9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
PICK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
DLGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
ACTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
HOMER3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
CLU
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
BAIAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHANK3
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SHANK3
|
PPP1R9B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
GOLGA2
|
ABHD17A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
DLG4
|
ABHD17A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
CALM1
|
ACTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
RASGRF2
|
ACTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
ACTN2
|
RASGRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
CALM1
|
AKAP5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9202019
|
APC
|
LRP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19116273
0807594106
|
CAMK2A
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
STXBP1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SQSTM1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PTK2B
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TRIM9
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FYN
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPD1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SHC3
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CLU
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MPND
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12485888
5215996
|
APP
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20573181
7894075
|
ESR2
|
APP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15040833
16675543
|
APP
|
DLG4
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
20573181
7894075
|
TRAF6
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0906941106
19955404
|
ARRB2
|
MDM2
|
â—¼ UBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5214648
11588219
|
DLG4
|
BEGAIN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
BEGAIN
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
RASGRF2
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
CALM1
|
RASGRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
CALM1
|
CAMK2D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20668654
|
CALM1
|
RASGRF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7637786
8756648
|
RASGRF1
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
RASGRF2
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
GRIN2B
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8294337
19453375
|
CAMK2A
|
GRIN2B
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
8294337
19453375
|
CAMK2A
|
KCND2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15071113
|
CAMK2A
|
HOMER3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18480293
|
FMR1
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
CAMK2D
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20668654
1000426
|
RASGRF2
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
CAMK2B
|
RASGRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
GRB2
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
LIN7A
|
CASK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16688213
5218615
|
CNTNAP2
|
CASK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215517
12093160
|
HNRNPC
|
CDC5L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
DLG4
|
CLU
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
CYSLTR2
|
GRIK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
CYSLTR2
|
PCMT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
GRIN2C
|
DBNL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RASGRF2
|
DLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
DLG1
|
RASGRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
RASGRF1
|
DLG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
DLG4
|
DLG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
RASGRF2
|
DLG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
ERBB4
|
DLG2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5212340
10725395
|
RASGRF1
|
DLG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
RASGRF2
|
DLG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
GRIN2B
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215250
11937501
|
GRIN2D
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215250
11937501
|
MED28
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7033846
16964398
|
NTRK2
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001478
23424281
|
RASGRF2
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
LRP1
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17360663
0611699104
|
KCNA4
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5215250
11937501
|
DLG4
|
MPP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
RALBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
LZTS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
GOLGA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
MT-CO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
PICK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
FTH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
MPND
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
THOC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLG4
|
HSPD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
DLG4
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
NOMO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
PEX19
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
PCMT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
LRFN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16495444
7569905
|
DLG4
|
PRR16
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
WDR74
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
RASGRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
DLG4
|
EEF1G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
TUBB2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
DLG4
|
TJAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
NLGN2
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9278515
18923512
|
NLGN3
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9278515
18923512
|
MAP3K10
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11152698
|
NLGN4X
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11368788
18923512
|
DLGAP4
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9115257
|
DLG4
|
LRFN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21736948
16828986
|
DLG4
|
TANC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21068316
15673434
|
FYN
|
DLGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLGAP1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLGAP1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLGAP2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLGAP2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
DLGAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
DLGAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
FYN
|
DLGAP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLGAP3
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLGAP4
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
SRC
|
DLGAP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DLGAP4
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
DRD1
|
PRKCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GRB2
|
DYNLL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
DYNLL2
|
HOMER3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
GRB2
|
EEF1G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
ERBB2
|
SHC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
KRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
NRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
HRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
ERBB2
|
SHC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16273093
|
ERBB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
ERBB4
|
SHC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16729043
16829981
|
FMR1
|
HOMER3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
FMR1
|
PICK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
SHC1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7516469
5220322
|
FYN
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9694876
7737275
|
MED28
|
FYN
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
16899217
6731769
|
LRP1
|
FZD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14739301
|
FZD7
|
PRNP
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
SHANK2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
HNRNPC
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
GRB2
|
HSPD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PCMT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PPP1R9B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRIA3
|
GRIA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0708699104
17989220
|
GRIN2A
|
LRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17360663
0611699104
|
GRIN2A
|
LRFN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16495444
7569905
|
RASGRF2
|
GRIN2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
GRIN2B
|
LRFN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16495444
7569905
|
GRIN2C
|
LRFN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16495444
7569905
|
GRIN2C
|
HSPD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
GRIN2D
|
LRFN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
16495444
7569905
|
GRM1
|
HOMER3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9808458
9069287
|
GRM1
|
HOMER2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9808458
9069287
|
GRM5
|
HOMER2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9808458
9069287
|
KRAS
|
HNRNPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
HOMER1
|
SHANK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10433269
17243894
|
HRAS
|
HSPD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
RALBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HRAS
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12695509
5216326
|
HRAS
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17138645
|
HSPD1
|
LZTS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
HSPD1
|
PRNP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8676499
16713569
|
RASGRF2
|
LRRC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
RASGRF1
|
LRRC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14622581
10373510
|
SRC
|
MED28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16899217
6731769
|
NLGN3
|
PICK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
NTRK2
|
SHC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12006576
9507002
|
PRKCA
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
7929214
12052829
|
RALBP1
|
PRKCA
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5217884
16087181
|
PTPRG
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
PTPRG
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
25624455
|
SQSTM1
|
RAD23A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
SHANK2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
TUBB2B
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
DLGAP3
|
SHANK2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
28179641
|
AKAP5
|
CALM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
CALM3
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
AKAP5
|
CALM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
CALM2
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
CALM1
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
DLG4
|
LLGL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
DLG4
|
LLGL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
DLG3
|
GRIN2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
DLGAP3
|
SHANK1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.81
|
0.81
|
Signor
|
28179641
|
KCNA1
|
KCNA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HuRI
|
32296183
|
ATP2B4
|
CALM3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
ATP2B4
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
LLGL1
|
LLGL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
818.0
|
0.81
|
STRING
|
36370105
|
PRKN2
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32814053
11679592
|
FYN
|
DLGP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32296183
17474147
|
DLGP4
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21653829
9115257
|
LRFN4
|
DYL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
HGS
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23208550
20505072
|
GRB2
|
CYLD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
DLG3
|
KCNA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
16637659
|
PICK1
|
FMR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21653829
31413325
|
NLGN3
|
NLGN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
NLGN3
|
NLGN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
SHC1
|
SHC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
SHC3
|
GRB2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
16829981
|
DLG4
|
5HT2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12682061
|
DLG4
|
IRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
10627592
|
DLG1
|
ACTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12860415
16713569
|
CDC5L
|
FUS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25192599
29884807
20467437
|
DLG1
|
GRIK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9808460
11279111
|
DLG3
|
GRIK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12070168
9808460
|
DLG4
|
FZD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12067714
|
ESR2
|
UBE3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33456993
25408199
17962381
|
KCNA5
|
KCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12815189
11149959
|
ERBB4
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
CYLD
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
CRIPT
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
834.0
|
0.83
|
STRING
|
36370105
|
DLGAP1
|
SHANK2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
28179641
|
FYN
|
GRIN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.83
|
STRING
|
36370105
|
SHAN1
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10433268
15255944
|
SYGP1
|
DLG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9581761
|
SYGP1
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9581761
21653829
|
APP
|
PRNP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
ARRB2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
ERBB4
|
DLG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10725395
12175853
|
DLG4
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9892651
12419528
16713569
|
GRIK5
|
GRIK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9466455
15583001
8288598
|
KCNA2
|
KCNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10428084
10428758
|
KCNA4
|
KCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10428084
10428758
|
KCNA3
|
KCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10428084
33961781
12944270
|
DLG1
|
KCNJ12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
DLG1
|
KCNJ12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
844.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
AKAP5
|
KPCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
9202019
8599116
11557526
|
AKAP5
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
DLG4
|
GRIK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12597860
|
KHDRBS1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
8374603
22641034
|
FYN
|
PTK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
SRC
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
12624098
9016807
16713569
16189514
11964172
|
ADAM22
|
LGI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
DLGAP2
|
SHANK2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
28179641
|
ERBB2
|
GRB2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
14967450
|
KIF5A
|
TUBB2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
LZTS2
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
29395067
|
HGS
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16713569
12151521
|
DLGAP1
|
SHANK1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
28179641
|
KCNA3
|
KCNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10428084
32296183
|
TRAF6
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
22447928
10635328
16189514
29545793
|
DLG1
|
DLG2
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
APP
|
CLU
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
DLG1
|
ERBB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24550280
12175853
|
DLG1
|
DLGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
MED28
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
16899217
16964398
|
ERBB2
|
ERBB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
GRB2
|
PTK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
HRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
CAMK2D
|
CAMK2G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
CACNG2
|
GRIA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
SHC1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
DLGP4
|
DLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
9115257
|
DLGP4
|
DLG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
9115257
|
DLG4
|
ACTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21653829
16713569
12435606
|
APC
|
DLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
30126976
23185543
|
KCNA5
|
DLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12970345
24550280
16466689
|
DLG1
|
KCNA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7477295
9341123
|
EXOC4
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12738960
12675619
|
DLG4
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10839362
16713569
|
DLG4
|
GRIK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9808460
11279111
|
SRC
|
ESR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11032808
12630920
15604093
11013076
12095943
|
NTRK2
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16713569
9648856
|
SHC3
|
NTRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9507002
19166614
12074588
|
HOMER1
|
HOMER2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
GRB2
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
GRIA2
|
PICK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
ARRB2
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
FYN
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
HOMER1
|
HOMER3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
RAD23A
|
UBE3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
DYNLL1
|
DYNLL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
DLG4
|
KPCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11937501
16713569
|
DLG4
|
DYL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10844022
16713569
14760703
|
CRIPT
|
DLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12070168
24550280
16713569
18951956
|
KCNA4
|
DLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
11997254
24550280
8938729
7477295
12860415
|
DLG1
|
KCNA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
LRP8
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10827173
16332682
|
SRC
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
16966330
31980649
28514442
19711372
9169421
|
MED28
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16899217
15467741
|
KCNA3
|
KCNA5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
28514442
18218624
|
SHC1
|
LRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11854294
12789267
12069755
|
NTRK2
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
26253177
16034442
12419535
10092678
28213521
|
CASK
|
DLG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
HRAS
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
KHDRBS1
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
895.0
|
0.89
|
STRING
|
36370105
|
ERBB2
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
ERBB4
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
KCNA5
|
ACTN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10812072
11389904
12860415
16713569
|
MDM2
|
ARRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18544533
21389118
21081496
33649538
32828283
17984062
32450252
12538596
21988832
15878855
26545496
12488444
21466165
11588219
|
DLG4
|
BAI1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23782696
11937501
|
CALM1
|
CAMK2G
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10860555
20668654
|
CAMK2A
|
CYLD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24614225
|
CAMK2B
|
CYLD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24614225
|
ESR2
|
CLU
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20034404
|
FYN
|
DLG2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
13129934
|
KCNA5
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12860415
12435606
16466689
|
DLGAP1
|
SHANK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10433268
28179641
12954649
|
SRC
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22973453
19704002
21075308
7542762
7797556
19372587
29720121
11940572
17875712
|
SHC1
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
30898150
10085134
9019162
24658140
22973453
16729043
9710588
28065597
16843263
9756944
16713569
16273093
8665853
|
PTPRG
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25624455
19167335
|
ERBB2
|
SHC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16273093
16729043
|
ERBB4
|
MDM2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15985438
|
FYN
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7499280
9344857
|
PTK2B
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
10679059
12626562
9763606
|
SHC3
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16729043
12242309
16829981
|
PTPRG
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
25624455
19167335
|
PTK2B
|
KCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9560226
11739373
7544443
|
SRC
|
KRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
30644389
26854235
9096340
|
RPS6KA1
|
MPP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
NTRK2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8808684
12419535
16034442
|
PTK2B
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
10679059
12626562
9763606
|
CALM3
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
CALM2
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
DLG4
|
KCNA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
CALM2
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
CALM3
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
ERBB4
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
SQSTM1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
DLG1
|
DLG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
26496610
12351654
|
GRB2
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
16273093
5218056
|
ERBB2
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
APC
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
HOMER1
|
SHANK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
LMO4
|
VMAC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HuRI
|
32296183
|
CASK
|
LIN7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
DLG1
|
LIN7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
24366813
14960569
|
DLG2
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
21653829
9182804
|
ATP2B4
|
CALM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
GRIK2
|
GRIK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
DLG4
|
DLGAP1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.93
|
0.93
|
Signor
|
18923512
|
GRIA3
|
PICK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
11891216
10027300
|
CALM3
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
CALM2
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
DLG4
|
DLG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
10026200
28973854
|
DLG4
|
LRP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
17360663
10827173
|
MED28
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
16899217
16964398
|
PICK1
|
GRIK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
11891216
12597860
|
PICK1
|
GRIK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
12597860
18692513
|
CAMK2A
|
CAMK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
ERBB2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
DLG1
|
IRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
11181181
32541000
30126976
|
DLG4
|
ADRB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
11526121
16316992
10995758
|
CRIPT
|
DLG3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12070168
11937501
16713569
|
NLGN1
|
DLG4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
30864948
11937501
9278515
|
ERBB4
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
24557338
30898150
8816440
16767099
25315821
10572067
10839362
21203579
|
CAMK2B
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
FYN
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
GRIA2
|
GRIA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
CAMK2A
|
CAMK2D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
PICK1
|
KPCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11007882
9405395
|
DLG4
|
CRIPT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9581762
20018661
16713569
11744724
11937501
|
SRC
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9388490
18840094
9710204
10482988
9096689
7499252
8939605
26551075
16189514
|
DLG4
|
DLGAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
AKAP5
|
PRKCA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
CASK
|
LIN7B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
SHC1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
12213123
8491186
8950973
9927207
9733714
8112292
10356320
11370743
32062451
8294403
16371368
22057045
9045692
9032244
8995379
7514169
9175774
9541596
8663178
7629070
9019162
7597091
7798267
9544989
9488479
8940013
10570290
15812354
11792427
8621719
24430869
7650032
11453982
16713569
7516467
10477741
8662733
11302736
26551075
9254595
7559490
12441060
8662998
8235613
12485888
28690151
16520382
8939605
11505033
9129019
11707405
15888547
8647288
7524086
25416956
24189400
11827484
12149229
8195171
21725358
9020193
10049786
9797459
9886492
33961781
9126968
8626525
7537740
12577067
11964172
12898421
8810340
22974441
19380743
9434624
10080542
9083103
21706016
15688026
7535773
31980649
8561895
7744881
|
CAMK2A
|
GRIN2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
DLG4
|
GRIN2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
DLG4
|
GRIN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CALM3
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
3006921
17353931
20668654
|
CALM3
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9952395
8625412
12379661
9728925
|
CALM2
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9952395
8625412
12379661
9728925
|
CALM2
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
3006921
17353931
20668654
|
NRAS
|
ABHD17A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
28630138
20418879
26701913
21779505
2661017
29311131
16000296
|
KRAS
|
ABHD17A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
28630138
20418879
26701913
21779505
2661017
29311131
16000296
|
HRAS
|
ABHD17A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
28630138
20418879
26701913
21779505
2661017
29311131
16000296
|
KRAS
|
CALM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
27410739
12727204
28666118
16043511
|
CALM1
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9952395
8625412
12379661
9728925
|
CALM1
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17145710
3006921
17353931
20668654
|
CAMK2A
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
12147342
11306676
19453375
21610080
16120608
8940188
11459059
22427672
16436603
|
CAMK2A
|
SYNGAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
14970204
12951199
11278737
15358237
15312654
9620694
|
CAMK2A
|
DLG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15044483
12933808
|
CAMK2B
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12147342
11306676
16436603
8940188
|
CYLD
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
12917691
12917689
16230348
29933112
18382763
|
DLG1
|
NET1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
30126976
19586902
24550280
17938206
|
GRIN2A
|
DLG3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12070168
9278515
11937501
|
DLGAP1
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9286858
9115257
9286856
11060025
22117215
10844022
10527873
9024696
|
NLGN1
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18923512
9278515
30864948
11937501
|
SRC
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
24981431
16990796
14529711
18721130
|
SYNGAP1
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
26356309
9620694
9581761
|
FYN
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12419528
25720756
18721130
9892651
16713569
22709448
|
DLGAP2
|
DLG4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9286858
9115257
|
DLG4
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
20018661
16990796
11997254
9278515
7569905
33000527
11937501
10488080
9581762
11723117
12738960
8601796
|
DLG4
|
ERBB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
17145710
10725395
16767099
17018285
10839362
12716924
|
DLG4
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10336672
16990796
9286858
8922396
12419528
21653829
9278515
7569905
12399578
11937501
18400955
10648730
11222640
17360663
11677266
8601796
|
DLG4
|
DLGAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9286858
9115257
18923512
9286856
11060025
22117215
10844022
10527873
9024696
|
DLGAP1
|
SHANK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10844022
10527873
28179641
|
NRG1
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12082616
8651595
10768865
12471041
12374700
|
PRKCA
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
16.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
11447289
19615955
16488589
6321473
8321321
12845332
11313945
18799465
9855018
12040186
19568798
15567848
14585353
|
NRG1
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
9275162
1350381
19293191
14737100
7514177
|
ERBB2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
31980649
9756944
21278786
16273093
24189400
11173924
9710588
24658140
11606575
14967450
17875712
16713569
16729043
|
ERBB2
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
16769082
19617202
11940572
12753909
21075308
7542762
|
ERBB2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
28065597
23331499
9756944
16273093
8026468
9710588
10085134
24658140
9590694
16713569
16729043
16843263
|
ERBB2
|
ERBB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17145710
10839362
8816440
24557338
16767099
21203579
10572067
|
NRG1
|
ERBB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
23331499
9275162
7721889
25052836
10970856
10214951
8062828
9565587
14967450
10537356
9168115
|
ERBB4
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
24658140
16829981
16729043
12731860
25140053
|
ERBB4
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16273093
16729043
24658140
|
ESR2
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11013076
12095943
12630920
11032808
|
FYN
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
9822663
15886116
10849438
12670394
|
GRB2
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
SHC1
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
PTPN5
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
22840751
16713569
11983687
|
NTRK2
|
FYN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
16713569
9648856
|
FYN
|
MED28
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17145710
16964398
16899217
|
FYN
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
96.0
|
1.0
|
Omnipath
|
19901323
20230923
16497976
9121430
15592455
16713569
9446569
17389395
23331499
18578522
10921922
10482988
10764799
18452278
20068231
10592173
18669648
12522270
9685404
10896916
7516469
9927207
12237775
8702728
8610109
19651622
9741627
9710204
19664994
17016520
10816433
11075717
|
FYN
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9670010
10458595
10195142
12932824
9892651
19834457
16713569
11677266
|
FYN
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
34.0
|
1.0
|
Omnipath
|
12451687
19477150
18673451
16713569
11024032
23162743
21686074
24611998
16190898
10458595
28497343
20722721
19874789
11483655
22009355
23127881
21896318
20053906
19482714
18932218
26229100
18691323
|
HGS
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
24828152
12686592
12551915
15828871
19109251
|
GRB2
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11283723
11335727
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
15863030
16000375
16002046
16076871
16102570
16212621
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19223473
19414323
19449109
19454690
19909365
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24027568
24217602
24346288
24670066
25922287
26201938
26552706
7510700
8551221
8837607
9157999
9570538
9753319
9763606
|
NRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
HRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
KRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
GRB2
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
69.0
|
1.0
|
ACSN
|
10022831
10086337
10358164
10567412
10811803
10849428
10982827
11166270
11283723
11335727
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15308668
15501236
15520864
15567848
15573129
15574420
15863030
16000375
16002046
16076871
16102570
16212621
16530705
16572188
16582911
16887996
17086423
17496910
17673906
17883421
18835194
19223473
19414323
19449109
19454690
19909365
21372296
21378271
22064427
22461508
22464172
23390297
23896411
24027568
24217602
24346288
24670066
25922287
26201938
26552706
7510700
8551221
8837607
9157999
9570538
9753319
9763606
|
PTK2B
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
9560226
10329689
8695788
16713569
19380485
9091579
10749687
10354709
|
SHC1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
198.0
|
1.0
|
Omnipath
|
8808684
9083103
8551221
9126968
8621483
25416956
9252386
8524223
7535773
8662998
11302736
11827484
8995379
9541596
9175774
10207047
7717978
17673906
7744881
11505033
10523831
24189400
9927207
7650032
8810340
9045692
23178716
19531499
15812354
9129019
10356320
12485888
9461587
8114695
7514169
9566877
8939605
16371368
15341520
7529871
10891441
10749687
7524086
26645482
8491186
10592173
10049786
9171350
11707404
7537740
15688026
8663178
19380743
11782427
9544989
16436051
9434624
16713569
21725358
11964172
17314098
11792427
8195171
1465135
12213123
8647288
12955078
10477741
11707405
12577067
9199344
10080542
8112292
7760801
10570290
11997181
7798267
16520382
10961885
8950973
21706016
9448048
8662733
11370743
8051109
9733714
8621475
9254595
8294403
10748054
8621719
8940013
12441060
22057045
7505797
24737791
20697350
9886492
18174162
18273058
8235613
7963520
7523859
|
SRC
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12624098
11964172
9016807
16713569
26103942
20554525
|
GRB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17496910
16713569
17673906
11352655
|
GRB2
|
KHDRBS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
10467411
20936779
21988832
7537265
9872323
8576157
11960376
11278465
9045636
21706016
16713569
12112020
7799925
|
PICK1
|
GRIA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10027300
11891216
25784538
24749734
|
PRKCA
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
9115280
8316301
11104776
|
SRC
|
GRIN2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10884433
10458595
10195142
23933820
12932824
10846184
29063113
26942227
19834457
33037073
11677266
26441533
20448061
|
PRKCA
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12147342
11306676
8940188
|
SRC
|
GRIN2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
10884433
18184784
11483655
11024032
|
PRKCA
|
GRM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10823959
15305863
17570479
|
PRKCA
|
GRM5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15894802
9242710
|
HRAS
|
NRG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
Reactome
|
23220880
25853726
30301790
28274957
18039657
16843263
25994018
26545934
22046346
18413839
23948973
26375550
|
SRC
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12695509
9626657
9020108
25157176
33413561
|
SRC
|
KCNA3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11812778
|
NTRK2
|
KCNA3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19166614
26655221
11812778
|
SRC
|
KHDRBS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
9038356
10467411
8766817
22745667
7537265
7516469
11960376
10635328
1374686
18606683
16169070
16713569
1545818
15190072
|
KRAS
|
NRG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
Reactome
|
23220880
25853726
30301790
28274957
18039657
16843263
25994018
26545934
22046346
18413839
23948973
26375550
|
PRKCA
|
KRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20802526
34333552
23331499
25713064
27791178
18458061
9922370
18182391
16483930
|
SRC
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
12789267
11854294
18381291
21650223
|
PRKCA
|
LRP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15272003
|
NRAS
|
NRG1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
Reactome
|
23220880
25853726
30301790
28274957
18039657
16843263
25994018
26545934
22046346
18413839
23948973
26375550
|
RASGRF1
|
NRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
1379346
9032266
11560935
9379834
9430727
7828890
|
SHC1
|
NRG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
12.0
|
1.0
|
Reactome
|
23220880
25853726
30301790
28274957
18039657
16843263
25994018
26545934
22046346
18413839
23948973
26375550
|
SQSTM1
|
NTRK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18457658
23331499
12471037
|
NTRK2
|
SHC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
23331499
9507002
19166614
12074588
16126371
|
PRKCA
|
STXBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
8631738
12519779
12950453
|
PRKCA
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12052829
19651622
18669648
17924679
|
PRKCA
|
SRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
24.0
|
1.0
|
Omnipath
|
17496910
11940581
21386996
10527887
2996780
11447289
19615955
16488589
6321473
8321321
12845332
11313945
2136766
17570479
12040186
19568798
15567848
14585353
|
PRKCA
|
RALBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
16087181
17706599
21411502
|
SRC
|
PTK2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
9560226
20028775
19919693
15585656
12495636
16713569
31979355
18083107
15105428
15778498
10593973
17389395
25349423
19534553
11149930
12486027
10329689
22581436
19380485
15166227
12526812
12522270
23109003
14963038
8849729
20001213
9556630
18935208
12345678
12231407
17192257
7529876
15695828
15070849
20381867
14739300
19369195
11274221
26866924
10777553
10521452
20521079
|
PTK2B
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16713569
7544443
10749687
|
SRC
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
55.0
|
1.0
|
Omnipath
|
19901323
9388490
8939605
9096689
10971656
16497976
15592455
9121430
10891441
17389395
11687594
10329689
10482988
20068231
17570479
16189514
9685404
23109003
7516469
9927207
18840094
15688026
15212693
1409579
14963047
9710204
26551075
17016520
11075717
|
TRAF6
|
SQSTM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
17.0
|
1.0
|
ACSN
|
11274345
12620219
14660645
15125833
15340068
15721744
16252010
17948050
18264787
18758450
18922473
19161412
20531300
21981924
25002027
26587781
28574505
|
TRAF6
|
SQSTM1
|
â—¼ SHARES_COMPLEX
|
|
|
17.0
|
1.0
|
ACSN
|
11274345
12620219
14660645
15125833
15340068
15721744
16252010
17948050
18264787
18758450
18922473
19161412
20531300
21981924
25002027
26587781
28574505
|
SQSTM1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
15870274
27458013
10747026
27681126
16079148
16189514
18382763
16874300
11244088
17389358
|