Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
APC LRP8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19116273 0807594106
GRB2 BAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CAPN1 BAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BAD APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BAD CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15725726
CAPN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18669646 0712034105
CASP3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EZH2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132185 21697275
CLTC FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
FMR1 HOMER3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FMR1 CAMK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
DLGAP1 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DLG4 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
APP GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12485888 5215996
DLGAP4 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK2 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SHANK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DLGAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DYNLL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 DLGAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 ATP5F1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CAMK2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
SHANK3 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HGS ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23208550 8428323
GRIN2A LRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17360663 0611699104
LRP1 DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17360663 0611699104
LRP1 FZD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14739301
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214648 11588219
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
CTNNB1 PKP4 â—¼   COLOCALIZATION 2.0 0.8 intact 5215447 12047349
ACTG1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF6 ARRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0906941106 19955404
TRAF6 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20501938
CTNNB1 FZD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12095419 15473860
FZD7 PRNP â—¼   PROXIMITY 2.0 0.8 intact 28298427 20167430
LIN7A CASK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16688213 5218615
APPL1 LRP2 â—¼   COLOCALIZATION 2.0 0.8 intact 21971085 8306957
DYNLL2 HOMER3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CYSLTR2 GRIK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
FYN CYCS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CYCS APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CREB1 CYCS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18227154 16908542
SHANK3 NEFL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
BECN1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DLGAP3 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN DLGAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK3 DLGAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SRC SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10964917 8755247
SHC1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7516469 5220322
PRKCA SHC1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7929214 12052829
PTPRG SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
HRAS SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17138645
MED28 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16899217 6731769
DLGAP2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DLGAP4 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK3 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
FYN CACNA1F â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN DLGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MED28 FYN â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16899217 6731769
HRAS SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12695509 5216326
HRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
ERBB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
AXIN1 CSNK1A1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11884395 23331499
APP BIRC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP8 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10409650 10911620
AP2S1 FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2A1 FZD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
DLGAP1 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
DLGAP2 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK3 SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC SPRR2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7216055 18155796
SRC MED28 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16899217 6731769
SRC ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6731430 11940572
SRC DLGAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PTPRG SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25624455
SHANK3 BAIAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
DRD1 PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BRAF PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16810323 5218785
PRKCA CACNA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8380626 9278528
PTK2B APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CREB1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17043650 16301994
CREB1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10698518
CREB1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10775268
MED28 DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7033846 16964398
APP DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20573181 7894075
SPRR2A DLG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7216055 18155796
DLG4 LRFN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16495444 7569905
DLG4 ACTN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
DLG4 DLG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
APP DLG4 â—¼   COLOCALIZATION 2.0 0.8 intact 20573181 7894075
MAP3K10 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11152698
NLGN4X DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11368788 18923512
DLGAP4 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9115257
NLGN3 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9278515 18923512
NLGN2 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9278515 18923512
DLG4 TANC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21068316 15673434
DLG4 LRFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21736948 16828986
SHANK3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CAMK2A APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SHC3 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHRNA7 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCTN2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CSNK2A1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR2 APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15040833 16675543
GRIA3 GRIA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0708699104 17989220
ACTN2 ATXN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
SHANK3 DCTN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 CLTA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HOMER1 SHANK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10433269 17243894
DCTN3 ACTR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
CTNNB1 PTPRG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8287660 21112398
CTNNB1 NRCAM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12183361 17724465
CTNNB1 BTRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15473860 10882123
ERBB2 SHC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
KRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
NRAS ERBB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
ERBB2 SHC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273093
CAMK2A KCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15071113
CAMK2A HOMER3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18480293
CAMK2A ADCY3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9768837 8798667
ESR2 AMH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 13678390 22689696
ERBB4 DLG3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212340 10725395
ERBB4 DLG2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212340 10725395
ERBB4 SHC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16729043 16829981
DCTN6 DCTN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
NLGN3 APC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GRIN2A NOS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17360663 0611699104
CAMK2D CAMK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20668654 1000426
CNTNAP2 CASK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215517 12093160
SHANK3 ACTN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GRIN2A LRFN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16495444 7569905
SHANK3 CAMK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GRM5 HOMER3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9808458 9069287
GRM5 HOMER2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9808458 9069287
GRM1 HOMER2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9808458 9069287
GRM1 HOMER3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9808458 9069287
SHANK3 DBNL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GRIN2C DBNL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SHANK3 SYNGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 HOMER3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 DLGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 SHANK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 DLGAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 DLGAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GRIN2C LRFN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16495444 7569905
DLGAP3 SHANK2 â—¼   RELOCALIZATION ✅ + 0.8 0.8 Signor 28179641
APC2 CTNNB1 â—¼   RELOCALIZATION ✅ - 0.8 0.8 Signor 10980707
ACTR1A DCTN3 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
APC BTRC â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
NRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 34591642
NRAS BRAF â—¼   PROXIMITY ✅ 0.81 0.81 mint 30194290
KCNA1 KCNA3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
DLGAP3 SHANK1 â—¼   RELOCALIZATION ✅ + 0.81 0.81 Signor 28179641
COX6C COX7B â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CASP8 TRAF6 â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
COX7B COX7C â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
GRB2 CYLD â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HGS ARRB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23208550 20505072
AXIN1 AXIN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22682247 20128690
COX6C COX7C â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31536960 33961781
SHC1 ERBB2 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
SHC1 SHC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARRB2 AP2A1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32962859 17620599
GRIA2 GRIA3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14687553 17989220
DCTN6 DCTN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NLGN3 NLGN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NLGN3 NLGN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SHC3 GRB2 â—¼   RELOCALIZATION ✅ + 0.82 0.82 Signor 16829981
AP2M1 APC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CASP3 MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 9278461 24842904 9840926 21726810
CDC5L FUS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20467437 29884807 25192599
ARRB2 TRAF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19955404 16378096 25425640
TRAF6 BIRC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20097753 24464131 23524849 29545793
DLG4 FZD7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12067714
AREG ADCY9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ARRB2 SRC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19202075 19122674 11877451 23242524
DLG1 ACTN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 12860415
DLG1 GRIK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9808460 11279111
ESR2 UBE3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33456993 17962381 25408199
DLG3 GRIK2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12070168 9808460
KCNA5 KCNA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11149959 12815189
ERBB4 NRG1 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CYLD TRAF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
AXIN2 CTNNB1 â—¼   DOWN_REGULATES ✅ - 0.83 0.83 Signor 11940574
DLGAP1 SHANK2 â—¼   RELOCALIZATION ✅ + 0.83 0.83 Signor 28179641
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
BECN1 TRAF6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
KCNA2 KCNA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10428758 10428084
BECN1 ERBB2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28205554 23703612 28628118 28351972
FYN GRIN2A â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
DLG4 FYN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12419528 16713569 9892651
DLG4 KCNA3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17854350 21726550 12435606 8938729
ERBB4 DLG3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12175853 10725395
KCNA3 KCNA2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 33961781 10428084 12944270
GRIK5 GRIK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 8288598 15583001 9466455
ARRB2 SRC â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
APP PRNP â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
BIRC3 TRAF6 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
DLG1 KCNJ12 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
AXIN2 APC â—¼   PHYSICAL_INTERACTION ✅ + 0.84 0.84 Signor 10911903
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
AXIN1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 7025676 19131971
SRC GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 11964172 9016807 12624098
TRAF6 CASP8 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27810922 16436380 30979779 16920630
KHDRBS1 FYN â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 8374603 22641034
DLG4 GRIK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12597860
FYN PTK2B â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
ERBB2 GRB2 â—¼   RELOCALIZATION ✅ + 0.85 0.85 Signor 14967450
DLGAP2 SHANK2 â—¼   RELOCALIZATION ✅ + 0.85 0.85 Signor 28179641
ADAM22 LGI1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
COX6C COX7C â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
HGS DLG4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 12151521
TRAF6 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10635328 16189514 22447928 29545793
KCNA3 KCNA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 10428084
BIRC5 BECN1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 26148234 20638385
DLGAP1 SHANK1 â—¼   RELOCALIZATION ✅ + 0.86 0.86 Signor 28179641
CASP8 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15254227 11832478 18669646 11437602 8962078
BIRC3 CASP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17069460 9384571
HRAS BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 34591642
HRAS BRAF â—¼   PROXIMITY ✅ 0.87 0.87 mint 30194290
MED28 SRC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16899217 16964398
DCTN2 DCTN6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27173435 26186194
DLG1 ERBB4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12175853 24550280
CLTC HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DLG1 DLGAP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
FYN CTNNB1 â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 12640114
GRB2 PTK2B â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ERBB2 ERBB4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CASP3 MDM2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
AXIN1 BTRC â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
CLTB CLTCL1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CAMK2D CAMK2G â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
APC DLG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 30126976 23185543
DCTN1 GRB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8955163 16189514
SHC1 SRC â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
SRC ESR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12095943 12630920 15604093 11013076 11032808
EXOC4 DLG4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12738960 12675619
DLG4 GRIK5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9808460 11279111
DLG4 ERBB2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10839362 16713569
DLG4 ACTN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12435606 21653829 16713569
CACNG2 GRIA2 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
KCNA5 DLG1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12970345 16466689 24550280
DLG1 KCNA3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7477295 9341123
HOMER1 HOMER2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ACTR1A ACTR1B â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GRB2 KHDRBS1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
FYN KHDRBS1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HOMER1 HOMER3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
RAD23A UBE3A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
BTRC CTNNB1 â—¼   UBIQUITINATION ✅ - 0.88 0.88 Signor 10228155
AP2M1 AP2S1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 AP2A1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
BIRC5 CASP3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 11170436 9850056
MED28 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16899217 15467741
ERBB4 GRB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16729043 22973453 24658140 25140053
SHC1 LRP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11854294 12789267 12069755
DYNLL1 DYNLL2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
LRP8 DLG4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10827173 16332682
DCTN1 DCTN3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 26638075 9722614 32814053 33961781 27173435
DCTN1 DCTN6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 27173435 26638075
KCNA3 KCNA5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 18218624
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
ACTR1B DCTN3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CASK DLG1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
KHDRBS1 SRC â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
ERBB2 SRC â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ARRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
AXIN1 APC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16199882 22682247 10228155 29045831 18786926 20128690 19131971 26496610 10811618 9734785 29713058 23277359 17510365
APC CASP3 â—¼   CLEAVAGE ✅ 3.0 0.9 Reactome 10200466 17297457 9973322
AXIN2 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10966653 10911903 9554852
PRKCA CAPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11950589 8070569 17570479
CAPN1 GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11553682 11677266 10846184
ESR2 CAPN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19376833
CASP3 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9348292
ERBB4 GRB2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PTK2B GRB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10679059 12626562 9763606
SHC3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16729043 12242309 16829981
AP2S1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12577067
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
MDM2 ARRB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17984062 15878855 32450252 26545496 12488444 11588219 21988832 21466165 33649538 21389118 18544533 21081496 32828283 12538596
ERBB4 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15985438
AREG ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7679104 23331499
ERBB4 SHC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9019162 22973453 24658140 16273093 16729043
SHC1 ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9710588 9019162 16713569 9756944 22973453 24658140 10085134 28065597 30898150 16843263 16273093 16729043 8665853
PTK2B SHC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10679059 12626562 9763606
FYN DLG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 13129934
APC2 AXIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9601641 10980707
ARRB2 AP2S1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20947020 17199046 12958364
SRC ERBB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22973453 11940572 17875712 19372587 21075308 29720121 7542762 7797556 19704002
SRC KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30644389 26854235 9096340
CAMK2A CYLD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24614225
CAMK2B CYLD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24614225
PRKCA BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1386920 16810323 12917261
PTK2B KCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9560226 11739373 7544443
KCNA5 DLG4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12435606 12860415 16466689
DLG4 KCNA2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12438413 7477295 12435606 8938729
DLG4 BAI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23782696 11937501
DLG4 LRP2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12713445 10827173 16713569
DCTN1 DCTN2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 26638075 33961781 22956769 26186194 27173435 34079125 22939629 26344197
DCTN2 DCTN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22863883 33961781 27173435 26186194 34079125 22939629
CTNNB1 BMP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10601040 12782598 15907834
CAMK2B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24117889
PTPRG ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25624455 19167335
ERBB2 SHC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16273093 16729043
ERBB4 NRG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10537356 9565587 28988771 8062828 7721889 9168115
KCNA5 ACTN2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11389904 10812072 16713569 12860415
DLGAP1 SHANK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10433268 28179641 12954649
CLTA CLTCL1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
DCTN3 DCTN6 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
ERBB4 SHC1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
GRB2 ERBB2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 16273093 5218056
DCTN2 DCTN3 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
DLG1 DLG3 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 33961781 12351654 26496610
BMP4 BMPR1A â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
ERBB2 SHC1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
APC KHDRBS1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
HOMER1 SHANK1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
DLG1 LIN7A â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 14960569 24366813
DLG2 DLG4 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 9182804 21653829
CTNNB1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5218183 16376880
CASK LIN7A â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
BRAF KRAS â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
GRIK2 GRIK5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
DLG4 DLGAP1 â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 18923512
SHC1 AP2M1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 31980649 19380743 24189400
CTNNB1 AXIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219694 17318191
APC2 CTNNB1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ACTR1B DCTN6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
COX6B1 COX7C â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
BRAF NRAS â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
DLG4 LRP1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10827173 17360663
AP2A1 SHC1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 8617812 28514442 16189514 31980649 24189400 11302736 33961781 19380743
MED28 FYN â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16899217 16964398
DLG4 DLG3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10026200 28973854
DCTN1 DCTN3 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
COX6A2 COX6C â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
BRAF HRAS â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
CAMK2A CAMK2B â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
ERBB2 GRB2 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CTNNB1 APC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 36950384
AP2S1 AP2A1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 31353312 16189514 7593184 33961781 26344197
NLGN1 DLG4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9278515 11937501 30864948
DLG4 NOS1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 8625413 10488080 9459447
DLG4 GRIK2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11276111 11744724 11279111 9808460 12597860
DLG4 ERBB4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16767099 10839362 17018285 12716924 10725395
DLG4 ADRB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16316992 11526121 10995758
ERBB4 ERBB2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10839362 30898150 21203579 25315821 24557338 8816440 10572067 16767099
ACTR1B DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAMK2B CAMK2D â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COX6B1 COX6C â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
GRIA2 GRIA3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
SHC1 GRB2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8940013 6169950
ERBB2 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9710588 11173924 21278786 16713569 9756944 24189400 31980649 22973453 24658140 30898150 16273093 17875712 16729043 11606575 8665853
AXIN2 CTNNB1 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
DLG4 KCNA1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7477295 12435606 11937501 8938729
SRC SHC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10482988 16189514 7499252 9096689 9710204 18840094 8939605 9388490 26551075
CAMK2A CAMK2D â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
BMPR1A BMP2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 19804412 7261592
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
ACTR1B DCTN2 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DLG4 DLGAP1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
ACTR1A DCTN6 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DCTN1 DCTN2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CASK LIN7B â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
BMP2 BMPR1A â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
SHC1 GRB2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 12485888 21725358 31980649 9126968 7514169 7744881 8235613 11453982 8662733 8491186 7629070 8940013 10570290 8112292 12213123 11302736 8662998 8195171 7597091 8810340 32062451 9129019 16371368 12149229 10049786 8626525 7650032 8950973 9488479 24189400 15812354 12441060 19380743 26551075 22057045 10477741 28690151 16713569 7516467 9733714 11827484 11964172 7537740 16520382 9019162 8663178 9797459 9032244 12577067 9927207 7524086 8995379 9886492 8294403 7559490 9434624 11792427 7798267 8621719 9541596 15688026 12898421 33961781 11370743 25416956 9544989 22974441 8939605 21706016 9083103 7535773 11505033 9175774 24430869 10080542 9020193 9045692 10356320 15888547 9254595 8561895 11707405 8647288
DCTN2 DCTN6 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
DLG4 GRIN2A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
AXIN1 CTNNB1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ACTR1A DCTN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BTRC CTNNB1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CLTCL1 AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CLTB AP2M1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
APC AXIN1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
APC CTNNB1 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
APC AXIN1 â—¼   PROTEIN_INTERACTION 26.0 1.0 ACSN 10421629 10581160 11487578 11955436 11967263 12051714 12554650 15001769 15327768 16039586 16288291 16940750 17143292 17318175 17936032 19619488 19751508 20006983 20705860 22270359 23343194 24023259 25730849 7542250 8638126 8666229
AXIN1 APC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 16199882 20128690 19131971 11297546 9554852 22682247 10228155 26496610 23277359 10811618 9734785
APC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 60.0 1.0 Omnipath 17145710 10545404 11166179 8259519 7890674 22083140 27902311 8638126 16212417 16798748 19061640 9286858 15327769 9482734 11533658 22056988 19576224 15327768 17318191 26496610 12628243 15355978 9065403 11712088 25241761 26910375 22682247 9065401 12000790 11707392 20219694 9707618 23840886 15525529 11251183 8628279 19631635 11972058 21664290
RPS6KA1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 62.0 1.0 Omnipath 11983683 10880354 20166139 9346240 11493700 9381178 15037618 11152955 15280015 10230394 10558990 8929531 10976111 18669648 10837486 10611223 15226424 22558198 12954615 18246127 10521512 10949026 15972258 10679322 18039929 18707149 12897128 16403219 17270021
BIRC3 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9990849 12042762 9384571 17069460
CASP8 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15755874 17179148 9501089 9950028 18669646 23308069 10988287 18458084 16964285 9885230 9765224 11437602 15014070 21295084 8962078 9208847
BIRC5 CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 9384571 11024045 9850056 10587640 16189514 16540654
CASP3 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 9278461 21726810 24842904 9840926
ESR2 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15313930 14764652 18607069 23891847 11986316 18223478 14729654
CTNNB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16628468 10318916 12095419 15111320 15735151 18679417 17360646 12782598 10201372 14557550 19778454 20300972 19662654 12589056 11943708 10915780 17693601 15592430 17109766
CREB1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23447091 16503642 18957421 9990041 12504100 10915780 15116100 22271686 14764597 16522741 18713830 24065533 10201372 22751440 18988190 12391146
CTNNB1 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 19751508 10318916 7542250 11967263 22290435 11836555 19623618 12663502 23343194 11955436 22270359 22761862 16039586 15810077 10201372 19020303 17143292 12051714 17208333 8666229 18974774 16940750 14712077 17666529 21285352 19619488 15377999
SRC CLTC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10089883 19289168 12237126
HGS GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
GRB2 BRAF â—¼   PHYSICAL_INTERACTION 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
GRB2 SHC1 â—¼   PHYSICAL_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 SHC1 â—¼   PROTEIN_INTERACTION 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 BRAF â—¼   SHARES_COMPLEX 48.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14764585 15169888 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 9510155
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
HRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
KRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
GRB2 SHC1 â—¼   ENZYMATIC_REACTION ✅ 69.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11283723 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 15863030 16000375 16002046 16076871 16102570 16212621 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19223473 19414323 19449109 19454690 19909365 21372296 21378271 22064427 22461508 22464172 23390297 23896411 24027568 24217602 24346288 24670066 25922287 26201938 26552706 7510700 8551221 8837607 9157999 9570538 9753319 9763606
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
ERBB2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 31980649 9756944 21278786 16273093 24189400 11173924 9710588 24658140 11606575 14967450 17875712 16713569 16729043
SHC1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 198.0 1.0 Omnipath 8808684 9083103 8551221 9126968 8621483 25416956 9252386 8524223 7535773 8662998 11302736 11827484 8995379 9541596 9175774 10207047 7717978 17673906 7744881 11505033 10523831 24189400 9927207 7650032 8810340 9045692 23178716 19531499 15812354 9129019 10356320 12485888 9461587 8114695 7514169 9566877 8939605 16371368 15341520 7529871 10891441 10749687 7524086 26645482 8491186 10592173 10049786 9171350 11707404 7537740 15688026 8663178 19380743 11782427 9544989 16436051 9434624 16713569 21725358 11964172 17314098 11792427 8195171 1465135 12213123 8647288 12955078 10477741 11707405 12577067 9199344 10080542 8112292 7760801 10570290 11997181 7798267 16520382 10961885 8950973 21706016 9448048 8662733 11370743 8051109 9733714 8621475 9254595 8294403 10748054 8621719 8940013 12441060 22057045 7505797 24737791 20697350 9886492 18174162 18273058 8235613 7963520 7523859
ERBB4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 24658140 16829981 16729043 12731860 25140053
PTK2B GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9560226 10329689 8695788 16713569 19380485 9091579 10749687 10354709
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
AP2A1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 12577067
GRB2 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10467411 20936779 21988832 7537265 9872323 8576157 11960376 11278465 9045636 21706016 16713569 12112020 7799925
GRB2 HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17496910 16713569 17673906 11352655
SRC LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 12789267 11854294 18381291 21650223
PRKCA LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15272003
CYLD TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12917691 12917689 16230348 29933112 18382763
DCTN3 DYNLL1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
ACTR1A DYNLL1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN6 DYNLL1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DYNLL1 DCTN1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DYNLL1 DCTN2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
CTNNB1 AXIN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24447505 15473860 11809809 22615875 11809808 12711682 11940574
CTNNB1 AXIN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10966653 19751508 7542250 8666229 17143292 11955436 11967263 23343194 22270359 9554852 22699938 16039586 16940750 9566905 19619488 15766563 12051714
ACTG1 BAIAP2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
DCTN1 DYNLL2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN2 DYNLL2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN6 DYNLL2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN3 DYNLL2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
ACTR1A DYNLL2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
COX7C COX6C â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX7C COX6C â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
SHC1 NRG1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
SHC1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
ERBB2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 28065597 23331499 9756944 16273093 8026468 9710588 10085134 24658140 9590694 16713569 16729043 16843263
PTK2B SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16713569 7544443 10749687
PRKCA SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12052829 19651622 18669648 17924679
ERBB4 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16273093 16729043 24658140
FYN SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 96.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 16713569 9446569 17389395 23331499 18578522 10921922 10482988 10764799 18452278 20068231 10592173 18669648 12522270 9685404 10896916 7516469 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
SRC SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 19901323 9388490 8939605 9096689 10971656 16497976 15592455 9121430 10891441 17389395 11687594 10329689 10482988 20068231 17570479 16189514 9685404 23109003 7516469 9927207 18840094 15688026 15212693 1409579 14963047 9710204 26551075 17016520 11075717
PTPN5 FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22840751 16713569 11983687
FYN GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9670010 10458595 10195142 12932824 9892651 19834457 16713569 11677266
FYN DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12419528 25720756 18721130 9892651 16713569 22709448
FYN MED28 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 16964398 16899217
FYN CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 20026641 22264731 24511551 25241761 22340496 12640114 25803041 26509276
HRAS NRG1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
SRC HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12695509 9626657 9020108 25157176 33413561
HRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 7706312 14970219 18567582 12932319 8073291 1386920 23331499 8601312 9154803 18988627 8668348 21779497 19541618 19933846 17563371 18098337 16803888 26165597 24441586 16135787 12917261 15710605 10545207
AXIN1 FZD2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
AXIN1 FZD1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11336703 17529994 18077588 17569865
AXIN1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 52.0 1.0 Omnipath 20128690 20531388 16890161 27902311 22509369 18593713 16199882 23331499 9482734 21071413 26496610 19244247 22773187 17318191 10196136 18988627 17208333 19131971 24976009 22682247 10228155 12805222 12000790 10488109 9501208 9601641 18632848 9554852 19166851 23959799 12421363 9734785 11940574
CTNNB1 BIRC5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19778454 17005722 19662654 11517919 16288908
SRC CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 27432652 16619028 19470771 27109099 27195913 19383910 30501030 24100030 22074016
CLTCL1 AP2S1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
FZD1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 7641885 15265686 19718039 21602792 210606194 8655584 19705439 19029934 20093472 17430994 21606194 17884187 14747478 22017973 22433869 17143292 20006983 19072724 14704854 16965538 16443747 22007144 16547521 19020754 20940130 21640127 21087212 17127310 21796133
ERBB2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16769082 19617202 11940572 12753909 21075308 7542762
PRKCA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 17496910 11940581 21386996 10527887 2996780 11447289 19615955 16488589 6321473 8321321 12845332 11313945 2136766 17570479 12040186 19568798 15567848 14585353
ESR2 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11013076 12095943 12630920 11032808
SRC PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 9560226 20028775 19919693 15585656 12495636 16713569 31979355 18083107 15105428 15778498 10593973 17389395 25349423 19534553 11149930 12486027 10329689 22581436 19380485 15166227 12526812 12522270 23109003 14963038 8849729 20001213 9556630 18935208 12345678 12231407 17192257 7529876 15695828 15070849 20381867 14739300 19369195 11274221 26866924 10777553 10521452 20521079
SRC CHRNA7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16251431
SRC KCNA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11812778
SRC GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10884433 10458595 10195142 23933820 12932824 10846184 29063113 26942227 19834457 33037073 11677266 26441533 20448061
SRC DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24981431 16990796 14529711 18721130
SRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 22605996 16492141 27177845 23824743 25423132 25850673 24816560 27203386 11836526 22515442 26918136 10593980 15782139 9592087 22056988 12571228 17087658 20840866 23640056 21195420 25164010 26453937 9278444 16831887 23476652 12123611 11279024 14517306 21903109 22200182 20026641 22264731 25041845 12408824 22247700
SRC KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9038356 10467411 8766817 22745667 7537265 7516469 11960376 10635328 1374686 18606683 16169070 16713569 1545818 15190072
PRKCA GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15894802 9242710
PRKCA NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 7694293 12630910 10400690 1375933 10874031
PRKCA GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9115280 8316301 11104776
PRKCA KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20802526 34333552 23331499 25713064 27791178 18458061 9922370 18182391 16483930
PRKCA GRM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10823959 15305863 17570479
PRKCA ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 18799465 9855018 12040186 19568798 15567848 14585353
AP2A1 CLTB â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
AP2A1 CLTCL1 â—¼   PHYSICAL_INTERACTION 16.0 1.0 Reactome 1847920 20448150 10559856 19713939 19776351 21883765 15916959 26403691 22863004 23891661 19809571 21445324 15339664 21613550 21779028 19296720
CREB1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11160957 11698596 12842905 9770464
CREB1 BDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17599098 19712055 25031400 11719924 21335064 32603820 14735135 11377882 19046370 22179316 21677163 17456785 23946409 17164818 9581764 18063565 9581763 16337876 20100784
CAMK2D CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11175347 12356771 15733869 22554507 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
CAMK2G CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
RPS6KA1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 11175347 12356771 15733869 11160957 11544482 15138267 11532940 9829964 7958915 10558990 12235136 11335727 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11909979
CAMK2A CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11175347 12356771 15733869 1646483 11160957 9668047 7958915 9829964 12235136 11970864 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11013247 11909979
CAMK2B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
DLGAP1 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9286858 9115257 9286856 11060025 22117215 10844022 10527873 9024696
NLGN1 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18923512 9278515 30864948 11937501
DLGAP2 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9286858 9115257
SYNGAP1 DLG4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26356309 9620694 9581761
DLG4 NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8922396 9459447 10488080 11052931 11031113 8625413
DLG4 ERBB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 10725395 16767099 17018285 10839362 12716924
DLG4 GRIN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 10336672 16990796 9286858 8922396 12419528 21653829 9278515 7569905 12399578 11937501 18400955 10648730 11222640 17360663 11677266 8601796
DLG4 DLGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9286858 9115257 18923512 9286856 11060025 22117215 10844022 10527873 9024696
DLG1 NET1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 30126976 19586902 24550280 17938206
CAMK2A CACNA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16982421 9278528
CTNNB1 CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 17666529 23343194 21285352 18974774 22761862 22290435 16039586 19619488 19623618 17143292
KRAS BRAF â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 24937142 16294014 12932339 7744815 9020159 15035987 16364920 11325826 16041367 24347342 12932319 10205168 21441910 23993095
KRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 1386920 23331499 19541618 8601312 14970219 18567582 16135787 12932319 17563371 12917261 19933846 21779497 17635919 19223544 15710605 8073291
NRAS BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 1386920 21478863 9368069 19541618 8601312 14970219 18567582 16135787 7935411 12932319 12917261 17563371 19933846 21779497 8073291 15710605
CSNK2A1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12700239 12432063
CSNK2A1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11877451 32863206
BTRC CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 68.0 1.0 Omnipath 23514615 17053147 22912335 17145710 27001857 20531388 18851830 12820959 24451375 18805092 25900982 11818547 16798748 19061640 19956254 23331499 24912152 19150432 22017875 24501426 28018973 16376880 21466614 27316454 19053519 26506240 14516475 25149538 10023660 22682247 10228155 9461217 24464578 18354482 26091241 10074433 12114015 9990852 14706645 18650423 25873176 19966869 25515538 20851351 22730322 24469040
ERBB2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 17496910 7702605 7999105 22558232 14517306 11245482 11950845 12040186 19568798 23576562 14585353 23640056
CSNK1A1L CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 11955436 17172446 12000790 19293931 11818547 12114015
APC2 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 23840886 10021369 8638126 16510875 10980707 10074433 9823329
NRG1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12082616 8651595 10768865 12471041 12374700
NRG1 ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 9275162 1350381 19293191 14737100 7514177
ERBB2 ERBB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 10839362 8816440 24557338 16767099 21203579 10572067
CAMK2A SYNGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 14970204 12951199 11278737 15358237 15312654 9620694
CAMK2A NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12630910 10400690 1375933 10874031
CAMK2A DLG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15044483 12933808
KRAS NRG1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
NRG1 ERBB4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 23331499 9275162 7721889 25052836 10970856 10214951 8062828 9565587 14967450 10537356 9168115
BMP4 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 8702914 26330344 20860622 21054789 11241215 8006002 16189514 7644468
BMP2 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 51.0 1.0 Omnipath 17145710 17483092 10880444 10712517 26330344 21054789 16672363 10881198 11263668 20860622 15064755 18937504 25938661 15621726 12700180 10692589 19804412
NRAS NRG1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 Reactome 23220880 25853726 30301790 28274957 18039657 16843263 25994018 26545934 22046346 18413839 23948973 26375550
GRIN2A DLG3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12070168 9278515 11937501
BMP5 BMPR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11580864 16189514
DLGAP1 SHANK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10844022 10527873 28179641
CAMK2G ADCY3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 9768837 8798667