Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H1-0 H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LMNA H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGA1 H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-3B H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H2AC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AC4 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H2AC4 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H2AC4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H1-4 H1-0 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-0 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RALBP1 RALB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
REPS2 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-3B H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20211137 20651253
H3C14 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
HMGA1 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H1-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EGFR CAVIN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18776048 0806158105
JUN JUND â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8922393 2504580
JUND TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9826775 9030359
EPN1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19054389
EGFR H3C2 â—¼   COLOCALIZATION 2.0 0.8 intact 5216105 12577067
HMGA1 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 PRKCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10220385
H3C14 H1-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGA1 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SEPTIN7 SEPTIN10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AAK1 REPS1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TRAF2 ABLIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LDOC1 ABLIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HOOK2 ABLIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ABLIM1 LDOC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
JUN AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12832543 11192249
RHOA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15884057 11748077
GCC1 AMOTL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FGFR1 AMOTL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21937427
AP2S1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2S1 AP2M1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
JUN CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18196534 17922191
PPP4C CCDC6 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 27880917
CDH1 SCRIB â—¼   COLOCALIZATION 2.0 0.8 intact 21701506 8203421
RALBP1 CEP57 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
CEP57 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEP57 GCC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
HRAS CEP57 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CLTC TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CLTC IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DLG4 RALBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HSPA5 DSP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGA1 DSP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EGFR HRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
EGFR HRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17673906
LMNA EMD â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 30488537
FGFR3 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 RALBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HDAC1 GPS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17895379 0706736104
GSN RALBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSF1 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19793920
HMGB1 TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18218727 19158276
HOOK2 RALBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
HRAS RALBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS RALA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19222999 6946495
HSP90AA1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
HSP90AA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TNIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBC JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
PIK3CG RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15009099 23331499
RALBP1 PRKCA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5217884 16087181
RAC1 PRKCA â—¼   COLOCALIZATION 2.0 0.8 intact 5218533 16628218
UBC RALBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5226445 17703191
RALBP1 TAX1BP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5226445 17703191
REPS2 RALBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9422736
UBC RHOA â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5217531 15710384
STAMBP UBC â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
DLG1 LIN7C â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
EGFR JUP â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
AAK1 AP2M1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 11877461
CCDC6 PPP4C â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCDC6 PPP4R1 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
AP2A1 AP2S1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RAC1 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 AAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
REPS1 AAK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2M1 REPS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 BMP2K â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP2S1 REPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
REPS1 BMP2K â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NUMB EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 25754235
EGFR LMNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24780295 26320552
JUN HDAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 17056544
HIP1R REPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LSR REPS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
JUN JUND â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649
EGFR AP2S1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24189400 25754235 24797263
EPN3 EPN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LMNA SYCE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24623722 25910212
EGFR HCK â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
EPN1 EPN3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 26186194 21115825
EGFR EMD â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24797263 28065597 20937808
GOPC JUN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 20195357
EPN1 REPS2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
AP2M1 BMP2K â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
AP2M1 REPS1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
C1ORF216 RALBP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
CCDC13 RALBP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
CCDC6 HDAC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20498639 22863883
PPP1R13B RALBP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
AP2A1 NUMB â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
RALBP1 ZNF707 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
AP2A1 AP2M1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
AP2M1 AAK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25852190 26186194 28514442 24189400 19380743
CASP8 TRAF2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HDAC1 GSE1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21258344 26496610 23752268 28514442
HMGA1 JUN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10357819 10428834
AAK1 AP2M1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
LDOC1 RALBP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
RALBP1 REPS2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
TAX1BP1 UBC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TNIP1 UBC â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
EGFR AP2A1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31959764 24797263 23956138 25754235 20029029 24189400 7534311
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
CBY1 RALBP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
CREBZF RALBP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
MSANTD4 RALBP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
RALBP1 SAPCD2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
AP2M1 AP2S1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
AP2M1 EPN1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 26186194
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR AP2M1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31959764 24797263 31980649 24067654 23956138 25754235 20029029 24189400
AP2M1 NUMB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 28514442 24189400 23211419
IKBKG TNF â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
LMNA TMPO â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
TNF TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
HSF1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PSMC5 UBC â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
JUND MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1527086 18071306 22493372
NUMB AP2A1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17203073 23211419 12942088
MYB CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17242210
RALBP1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21686269 7623849
EGFR CDK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18271526 15657067 24658140 31980649 23956138 25402006
RHOA DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
RAC1 DLG4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9870943 9870942 16202622
PLCG2 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 22973453 25241761 25402006 16273093
EGFR RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18955552 20937854 15156151
PRKCA EMD â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 22986494 8463284 8034666
HSP90AA1 GTSE1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
HRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
LMNA PRKCA â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 22986494 8463284 8034666
PRKCA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10592173 11284700
EGFR PLCG2 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
CCDC6 RALBP1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
BANF1 LMNA â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
BANF1 EMD â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
AP2M1 RALBP1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
STAMBP UBC â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
IKBKG UBC â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
HRAS PIK3CG â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
RALA RALBP1 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
RALBP1 REPS1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
AP2A1 AP2M1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
AP2A1 AP2S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EMD LMNA â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CDH1 JUP â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RALB RALBP1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
PPP4C PPP4R1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2M1 AP2S1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
H1-0 HMGA1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 15621527 23964094 17242207 17158953 15655109 17242198 16901784
RALB RALBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 7673236 21686269 14525976 16189514 21241894 9422736
CDK1 EPN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 10764745 17570479
AKT1 H3-3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12588998 12529330
AAK1 AP2M1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11877457 11877461
AAK1 NUMB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25904845 18657069
RAC1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
RAC1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 20338997 15808505 20138985 20214616 21474067 19568798 15169778 19720745 18925875 10949026 11715018 19143635 12393431 18636226 10617634 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
AKT1 SKI â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19875456
AKT1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20837477 20098747 17660512
AKT1 PFKFB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 28235572 15896703
CLTC AP1M2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
PPP4C BANF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24265311 16495336
BANF1 EMD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25910212 22399800 11792822 25502805 17620012 31515488 32814053 32296183 12163176 11792821 16189514
TRAF2 CASP8 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15024054 20696707 19278658 10837247 19416807 21235526
CDK1 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20937773
TRAF2 CASP8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 17145710 12887920 20203691 16227629 21741934 17047155 22421964 30054040 11340079
LMNA CCNB1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22986494 2188731 2344612 2188730
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CDH1 TNF â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 11884419 16424155 16461340 17307799 17617594
HDAC1 CDH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20580679 19182791 21685935 21184735 24424621 18794357
CSNK2B CDH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10837139 20976471 20558317 10671551 17374729 21285348 11972058 21506126 11689703 10747897 16707567
CDH1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17548604 10969083 15662113 31980649 14681060 25241761 24189400 25468996 24658140 25402006
LMNA CDK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22986494 2188731 2344612 2188730
CDK1 LMNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 19007248 16565220 20166139 17081983 18767875 20393185 23870088 17137347 19413330 18187866 19194518 30190500 19664995 19415658 15302935 7925482 16083285 95010153 24741066 20068231 18452278 18077418 17570479 18491316 18669648 32071079 23427156 2344612 18691976 26922519 17287340 18815303 20068230 19651622 20058876 19691289 17924679 22367880 19165338 19664994 18707149 21389115 16964243 18212344 24556839
CDK1 HMGA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 31.0 1.0 Omnipath 17081983 20068230 17924679 17960875 20068231 2168176 17570479 1939057 19413330 20123066 19664995 18669648 15302935
CDK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 17145710 31980649 8360196 23956138 15901825 28150246 18271526 15657067 24658140 25402006 15302935
CDK1 CSNK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16335537 1939094 19007248 17081983 25788269 18691976 20230923 20068231 19387552 17570479 12551973 12396231 19581576 7578274 18669648
JUN EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16170369 23455325 15923621 16423552 10803405 18604200
HCK EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 31980649 24658140 11160627 25402006 23397142
PRKCA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 11447289 8321321 11313945 25402006 12040186 20888375 15302935 6321473 1860884 12878187 6090944 19568798 14585353 17496910 21386996 24658140 2984676 11940581 31980649 15212693 85012702 19615955 2987962 12845332 3379075 7805884 10816576 15567848 16488589
EGFR PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 31980649 25241761 16273093 24658140 17570479 25402006
HRAS FGFR1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HCK PLCG2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19901323 12181444 11606584 14656219 7682059 15144186 11507089 16497976
HDAC1 TNF â—¼   DOWN_REGULATES ✅ - 15.0 1.0 ACSN 10754326 10952726 11875494 12907458 14660645 14668329 15465827 15644117 16878026 17404308 17485448 21234400 22796940 23390297 7594497
TNF HMGB1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10925299 11112697 11438547 11875494 12646658 12811837 1431106 14607933 14625680 15099563 15699106 16713974 17916596 18633355 19411070 20038811 20184663 20435894 21133840 21411734 21826665 22595692 22955274 23170255 23430059 23508573 23510023 23567181 23769623 24092389 24378531 26201938 8910423
HRAS PIK3CG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9069260 9727023 17145710 10922060 11136978 21779497
HSF1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9880553 21932106 10440232 19818013 20045681 20668218 15706094 17965413
TNF IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TRAF2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TNF IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TRAF2 IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
TNIP1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 16684768 18212736 20010814
JUN TNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 12759366 11087751 7935377 21059644 16881863 24548427 12509451 9826775 10318823 8998076 18408586 15546613 20164416 7896795 9211933 10952728 9566900 23583459 10748079 24009130 10954918 10754326 9813054 10837498 9988757 11739517 16365438 19285436 16199883 8816436 10551799 8552071 9160673 11490006 21098092 16483936 10688670 10913190 16888805 9030359 25567680 9760243
JUN MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 1527086 8670250 12475180
PRKCA LMNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 17081983 16565220 20166139 18767875 19562805 19413330 8477740 19664995 12112001 19415658 7925482 16083285 95010153 20068231 18669648 18691976 19651622 19691289 17924679 18707149 93238752 16964243 18212344
PLCG2 RAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17540168 11278486 11804587 12670394
PRKCA RAC1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10679481 10871288 16492141 18851840 20027184 21474067
PRKCA RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16628218 20027184 11284700 18851840 21474067
PRKCA RALBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16087181 17706599 21411502
RALBP1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7673236 32203420 9395447 16189514 21686269
RALA RALBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 28851898 7673236 10364219 25241761 10393179 7623849 14525976 9422736
TRAF2 TNF â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNF â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 TNF â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10820262 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12433365 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18345002 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730