H3-4
|
H1-5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
REPS2
|
H1-5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
REPS2
|
H3-4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
EPN1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19054389
|
GRB2
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
AP2M1
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
AP2M1
|
AP2A1
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
15749704
15911768
|
GRB2
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
CBL
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17255943
5219572
|
GRB2
|
BIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
REPS2
|
BIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18647389
7027453
|
GRB2
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
MYO6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
REPS2
|
RALBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
9422736
|
REPS2
|
TRAPPC2L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21827752
8201468
|
RBP1
|
EPN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20709745
12775724
|
TPC2L
|
REPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
21827752
|
TPC2L
|
REPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25416956
|
AMPH
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
AP2M1
|
REPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
MYO6
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29467281
26950368
|
AP2A1
|
AMPH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
12057195
|
AP2A1
|
RBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
31980649
10764745
|
EPN1
|
REPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
AP2M1
|
REPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
AP2A1
|
AP2M1
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
EPS15
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
26186194
28514442
24189400
19380743
|
RALBP1
|
REPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
31959764
24797263
23956138
25754235
20029029
24189400
7534311
|
EPS15
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17474147
7797522
19109251
|
EGFR
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
AP2M1
|
EPN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
28514442
26186194
|
EPS15
|
AP2A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
8662627
9049247
10764745
19380743
10953014
|
EGFR
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31959764
24797263
31980649
24067654
23956138
25754235
20029029
24189400
|
REPS2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18647389
9422736
|
CBL
|
EGFR
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
20332299
|
EGFR
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
16829981
|
AP2A1
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
RBP1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
26186194
16713569
10910768
28514442
16189514
|
GRB2
|
ASAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
21706016
31980649
20936779
21988832
28514442
19380743
17474147
|
EGFR
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23158001
24797263
25872741
31182136
10635327
26055326
14505571
15210722
32714745
23774213
19155296
11370743
19836242
8665853
19947936
18271526
25140053
15668240
22394513
17486068
33323455
32377695
22203672
17182860
12604776
14627991
15383614
23153581
15735736
28541302
16849543
17242169
20562913
32904620
9121472
15677445
7782294
16923119
17995934
19531499
15465819
31959764
32114396
23457600
29629558
18316398
23799367
24714105
31120930
12061819
16713569
7657591
33617900
10086340
19225046
33762435
23175185
16729043
28791635
16246327
28198003
15962011
22266821
15117950
27059931
10428778
12734385
8662998
25005938
27903975
16969069
26177020
8798643
10799548
9756944
15159412
19578043
15657067
18255265
23418353
25754235
22976291
17545148
12803489
18319245
19713535
7592693
30544639
15107835
11994282
17971399
16105874
15282549
20940296
23897813
9130710
18273061
18508924
17880946
20124286
12593795
16914641
20877636
10092522
25521828
11408594
22591401
9890970
20308550
22833562
21772844
33627783
11239464
|
EGFR
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18271526
15657067
24658140
31980649
23956138
25402006
|
RBP1
|
REPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
9395447
26344197
31980649
32203420
28514442
23414517
|
GRB2
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.91
|
0.91
|
Signor
|
11823423
|
EPN1
|
EPS15
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
AP2M1
|
RALBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHOSPHORYLATION
|
|
|
0.92
|
0.92
|
Signor
|
11726515
|
RALBP1
|
REPS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
BIN1
|
AMPH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
33961781
9348539
31413325
28514442
9315708
|
CBL
|
EGFR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16914641
7033849
028274
|
RBP1
|
REPS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
33961781
28514442
9422736
|
AP2A1
|
AP2M1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
EPS15
|
EPN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10791968
18375383
18200045
15809337
9723620
21115825
16429130
|
GRB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16729043
5218694
|
CBL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CBL
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDK1
|
EPN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
10764745
17570479
|
EPS15
|
EPN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
16429130
18375383
35044719
9723620
10393179
18200045
15809337
21115825
10791968
|
AP2A1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
12577067
|
AP2M1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
23956138
31980649
24189400
19351721
20029029
24797263
|
AR
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
15305378
19318561
21613411
19258514
15650253
17242169
18692155
15288768
11556855
20610535
|
CDK1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
26573794
12569365
22275373
25704883
17043241
23321516
9725910
24480624
21799006
24424504
28062857
21820033
25950519
28415597
27450452
25691442
21782001
|
AR
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18358509
12534934
22260327
15288768
18951974
|
GRB2
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
25036637
25872741
8950973
917890
7642581
17944804
15210722
9108392
20936779
8695851
19836242
14725908
169092
28514442
9541596
9174058
11823423
12941616
10829062
10570290
7544353
11792427
8083187
15677445
8621719
9233773
9311917
23799367
16713569
10086340
9234717
8995358
25814554
9716598
11997436
7791764
8943292
8063801
8995445
8662998
11263968
16906159
8626404
9129019
98621719
17072306
9242692
10521482
9872323
8647120
7592693
9092538
10025673
17971399
17094785
9851874
11399323
33961781
9259313
18273061
7537740
8649804
9295052
11964172
9367879
20124286
10204582
19380743
9434624
21706016
8900205
9178909
12839496
9461587
31980649
11133830
33627783
8824292
8621483
|
GRB2
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
26.0
|
1.0
|
ACSN
|
10086337
10426994
10567412
10811803
10982827
11447289
11777939
11777960
11907067
12175651
12640133
15536084
15567848
15574420
16339513
16582911
16713974
16887996
17070508
17100878
17496910
17673906
18490724
19449109
26552706
8551221
|
CBL
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
188.0
|
1.0
|
Omnipath
|
34609770
16105874
18273061
22239438
24797263
20332299
17635922
23158001
17545148
8662998
12604776
9890970
23153581
17182860
25872741
12593795
23175185
10092522
15107835
22266821
22833562
24714105
17242169
25140053
20124286
19531499
9756944
10086340
22203672
19225046
16729043
15282549
20562913
22394513
20940296
23331499
7592693
19713535
10635327
19836242
15465819
15210722
25521828
23897813
10514377
12734385
18508924
11994282
20877636
33323455
22976291
23774213
23027125
15159412
18255265
16246327
28541302
16849543
23799367
16713569
10799548
8798643
19155296
9121472
17486068
21772844
16969069
15677445
15962011
23418353
12803489
32714745
14505571
27903975
19578043
26177020
11239464
18319245
11408594
10428778
12061819
17995934
17971399
27059931
26055326
15735736
23457600
7782294
22591401
29629558
11370743
7657591
21071413
28198003
18316398
19947936
9130710
18271526
15657067
31182136
16923119
17880946
32904620
15117950
14627991
15668240
15383614
|
CBL
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
158.0
|
1.0
|
Omnipath
|
11823423
8621483
9242692
18273061
17635922
16906159
8626404
8662998
9108392
9541596
98621719
9295052
25872741
17372273
8824292
8943292
12941616
20124286
19531499
10086340
8063801
9129019
9590251
11263968
9461587
7642581
10521482
10204582
8995445
8900205
7592693
9716598
8083187
14725908
17904548
7791764
9178909
25036637
8695851
19836242
7537740
15210722
9108316
169092
9311917
10514377
9092538
17072306
19380743
9872323
9234717
11997436
23799367
9434624
16713569
10829062
9367879
11964172
12839496
15677445
9851874
11792427
17094785
20936779
10570290
917890
17944804
25814554
17971399
11133830
8950973
21706016
8995358
9233773
10025673
8621719
11399323
9259313
9174058
8649804
|
CDK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17145710
31980649
8360196
23956138
15901825
28150246
18271526
15657067
24658140
25402006
15302935
|
EGFR
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
EGFR
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
109.0
|
1.0
|
Omnipath
|
9544989
10595738
23956138
27059931
10026169
16273093
11726515
24697349
21596750
19289468
7518560
21706016
23799367
9050991
16317285
16713569
25402006
11370743
24797263
8647858
8887653
9416834
21278786
16799092
8662998
10229072
11896612
7592693
19509291
8810325
24189400
19836242
11960376
7506413
18271526
15657067
10085134
24658140
17242169
7510700
8940013
7650032
8810340
11084343
12577067
7527043
31980649
11408594
19531499
20124286
23178716
9886492
23181695
9020117
8479540
14679214
12648464
1322798
17991782
16729043
17971399
|
EGFR
|
EPS15
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
17145710
17389395
10953014
24269888
19534553
25260758
19583965
19690332
15951569
9049247
17016520
|
EPS15
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7797522
17474147
19109251
|