Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ESR1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21920899 23658738
TP53 STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17108107 21317932
TP53 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23995788 21317932
CREB3 TAF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17483474 0608570104
CREBZF TAF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17483474 0608570104
TP53 PRKAA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15866171 24874608
TP53 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12392301 22242153
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
TP53 SERPINB5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
ZNF512B CREBZF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NFE2L2 NFE2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24613345 15790560
ESR1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24641954 20623181
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
NR1H3 PRKAA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19125418 20395595
SREBF1 BGLAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9138075 9121491
ESR1 TAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
TP53 WT1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ATF4 NFE2L2 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
CREBZF RALBP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
SIRT1 TP53 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CREB3 HCFC1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
BACH1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19897490 15734732
SSRP1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12437983 12684063 10385428
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
NFE2L2 ATF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21087962 23618921 20185790
ESR1 CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
ESRRG PDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17079227 23050013 19690166
CREB3 HCFC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 18391022 15705566 12271126 9658067 23583719 9389645 10871379 33961781 26186194 12235138 9271389 10629049
NR1H3 ACACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20139635 11027684 24265317
SIRT1 STK11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 15205477 15744310 15989956 18687677 19590512 19960022
SIRT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 18235502 11672523 18235501 15205477 35931247 15989956 17964266 25280219 19047049 16713569 19960022 21245319 12006491 19590512
SSRP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15171726 23810005 1406642 19946334
PRKAA1 STK11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 14511394 15579580 8779952 14985505 14614828 11018120
STK11 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20815019 11430832 17108107 16713569
STK11 PRKAA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 16434556 25792737 14985505 14976552 20489196 21062936 20656472 20616029 17255104 16041368 25696921 21399626 12391032 20160076 17244528 15980064 17054914 22517326 14532170 21918180 28694351 18693249 26771234 20801214 16600998 18195011 28723898 16912160 22039048 26068970 14614828 19884317 25679763 22575644 19197243 27864418 30022161 25683918 18303014 17287464 15327994 12764152 16054095 15509864 26506235 14511394 27181208 28625738 25874865 8910387 17276402 26247630 21680840 19414597 23418352 24289924 15383373
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
TP53 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12734185 19861536
TP53 SERPINB5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12011991 15578720 17700520 10692390 17204482
WT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16713569 10744705 8389468
PRKAA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28797070 15866171
CREBZF ATF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20102225 16343488 23661758
ESR1 XBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12954762 12047351 14605097
ESR1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20616010 20068169 16950141 21029304 19433249
NR1H3 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18490833 19716432 15330762 19366697
HCFC1 CREB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 10871379 17145710 12271126 26186194 15705566 18391022 12235138 10629049 9271389 9658067 23583719 9389645
NR1H3 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19378344 22160584 20005944 11287605 22183856 17522048 22641099 23499676 24265317 11790787 19903962
NR1H3 SREBF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 18854425 19366697 16831124 19933273 24277692 18202130 20868688 16112614 26120082 15855229 12730331 24265317 21094755 22511764 19716432 21266776 11287605 11694526 18420801 22984430 18684130 24458133 21540177 21979752 19258656 15330762
PRKAA1 SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21459323 21892142 23825667
PRKAA1 ACACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19651622 11052978 20166139 9029219 18669648 18767875 2900138 12015362 20068231 18707149 7907095 7915280 16326698 18212344
SREBF1 ACACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12871210 23300015 20139635 11994399 22279139 11907029
SREBF1 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 10585876 16601238 20373869 11855808 20067991 18413311 12897158 11110846 17449569 18226595 16834571 15220339 17956315 12177166 19244231 17313375 16308421 23300015 11287605 17197698 11082286 11790787 12440974 10520861 17531980 18420801 18774944 11443121 16891625 20130133 20371699 18682402 22279139 18281474 21447637 11530940 22331133