Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
UBE2I ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
CHEK2 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
MDM2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19816404 21986495
CHEK2 ATM â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
ATM EYA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 19234442 19351884
SP1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15837784 11466608
HMGA2 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21339738
ATM HMGA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21339738
CDKN1A DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19541625 0812254106
AKT1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12244303 11231573
RB1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9671466 14527674
PML CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10356361 16007146
NUPR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22858377 18690848
CDKN1A TP53 â—¼   COLOCALIZATION 2.0 0.8 intact 16616141 5218511
CCNA1 CDKN1A â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
STAT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17992189
AR CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10076995
DDB2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678110
PPARG CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15041706
EGR1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12690110
TGFB1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23741479 12058028
CDKN1A POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678112
CHEK2 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
CHEK2 H3-4 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
RB1 CHEK2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17380128 5219804
CHEK2 MDM2 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 15862297 5217705
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
SIX1 EYA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12783782 20110314
HTRA2 BIRC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11583623 5214623
CEP70 KAT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
KAT7 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212855 10930412
KAT7 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19307749 19411311
KAT7 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20439113 11395507
TP53 MAPK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21187340 16050810
EGF MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17081983 16024629
RB1 MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218170 16374512
PML MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
UBE2I MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12393906 20972456
HIF1A MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12606552 15385570
MDM2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 5216620 12915590
EZH2 MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19749796 23349306
MEN1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12837246
AR NEDD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 18703514
TP53 PML â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
H3-4 POLK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16678112
SP1 POLK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17099721
TERT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18775701 6742757
TFAP2A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19701232 18754863
SPI1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17967894 7988559
PPARG TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16556873 19912441
AR TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19481544 7103716
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
TP53 POU4F2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17145718 25356872
TP53 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SALL2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082782 24040083
MAX TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7969121 10348347
TP53 SLC31A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24799195 21422812
TP53 SLC10A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21239614 9502429
TP53 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18980971 16636674
TP53 DAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24217921 20943371
TP53 NDRG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18689861 20673333
TP53 EGR1 â—¼   COLOCALIZATION 2.0 0.8 intact 5216887 14744935
MYCN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20145147
TP53 FASLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10969818
TP53 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16917513
TP53 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
TP53 ODC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
HIF1A IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17504662 15723200
ATF1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10540320
SP3 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19564345 10861063
SP1 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18843277
SP3 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20154735
MAF IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15749884
ATF1 IL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20154735
IL10 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12773629
STAT1 S100A10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12645529
WT1 CIAO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9556563
EGR1 SPRY1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21826097
KDM6A RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20123895
STAT1 CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10773351
STAT1 CEBPE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16918696
STAT1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9880553 10440232
STAT1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19646959
STAT1 FASLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12108949
STAT1 IRF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19161415
EGR1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21283769
RARA PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10361124
PPARD MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12419217 21496113
ETV7 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16722933 11556732
CREBBP MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15894584
SP1 CCL5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19124744
TFE3 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20713358 21389977
REL TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21371435 23195252
EGR1 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12384981
TGFB1 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10362813
ITGA4 ITGB7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12626562 19454690
ITGA4 ITGB7 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 12626562 19454690
MYCN HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
SP1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12847090 5216518
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
HDAC1 MYCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18003922 0705524104
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PPARG HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21151932 16431920
UBE2I HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25704882 22493095
RB1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211419 10228159
AR SIN3A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18945670 16254079
AR NCOR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19351840 20610535
PPARD CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20592029 19395102
MAX CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11511535 10508165
EGR1 FASLG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11909874
DAPK1 SNURF â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
PPARG FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12921977 17320065
PPARG CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15741503 17237441
EGR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12011097
PPARG NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10848596
SPI1 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18227805 12393465
SP3 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11698458
SP1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9199305
WT1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11960373
EGR1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9199305
SP3 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24219545 10446912
SPI1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14559995 12588990
SPI1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22105598 12032776
SPI1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24503536 19423615
RB1 SPI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8434021
SPI1 CSF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SPI1 CSF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
SPI1 ELANE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9689920
SPI1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8264604
SPI1 CSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15676205
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
HIF1A CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17382325 5219810
SP3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12200429 20096088
SS18L1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14716005 15488321
CREBBP H3C14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11509556
CSF2 PRKACA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10477722 10949031
CEBPB CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7513199 21455770
SP3 CSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8407965 8981362
IL3 PRKACA â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10477722 10949031
THAP1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
GOLGA2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CCDC33 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
U2AF2 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 GOLGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
HIF1A HDAC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19071119 6802010
HIF1A FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16601206 15192019
HIF1A NKX2-5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21055290 18303027
HIF1A BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 17043658
HIF1A SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19934262 15780936
HIF1A MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18400834 18588890
ATF1 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7499271
EGF MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20178463 17081983
SP1 EGR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20121949 7384875
SP1 FGFR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11981041 15475466
SP1 CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16516150 15818598
SP1 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12888575 18481199
SP1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12683994 18064385
SP1 NES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15135078 19245830
SP1 CALCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7721877 18353772
SP1 CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20371701 8751713
SP1 HDAC4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16280357
SP1 CD34 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10989198
RB1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10850422 7732011
SP1 ABCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17272513
ATF1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10391889
EGR1 SLC5A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21386735 24647588
EGR1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17011549 12890669
SP3 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12637574 12888570
IGF1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19183465 12875741
RARA IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14715249 9153223
AR IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16825320
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NFKB1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18031796
AR MEF2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23598283 20610535
HDAC4 MEF2C â—¼   COLOCALIZATION 2.0 0.8 intact 5215014 11792813
HDAC5 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10737771 11062529
NFKB1 GDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9729303
NFKB1 NFKBIZ â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20220144
NFKB1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21790895
NFKB1 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9294162 9733516
EZH2 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21465172 19351856
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
CEBPB MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21917825 19723873
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
TFE3 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14962802 11818452
CEBPB CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11994385 8751713
CEBPB GHRHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15299028 22074460
CEBPB SLC5A5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15785238 18682709
UBE2I H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
WT1 UBE2I â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8798754
SMAD1 CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18668566 20522428
AR SMAD1 â—¼   COLOCALIZATION 2.0 0.8 intact 5219486 17183365
WT1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10470095
MYCN ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23440295 19960435
ATF1 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10683356 7843287
ATF1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10698518
AR CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20337887 20610535
AR GRP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19117998 17079466
AR RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12069693 20610535
AR GHRHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1428232 19533338
AR ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23368743 20610535
EZH2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 23239736
AR ODC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9570735
AR TMPRSS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10485450
AR FGF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12140757
RXRG RARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RARA CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18829110 23062266
RARA GHRHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12645859 8625613
RARA CEBPE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14576045 12032776
EZH2 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
EZH2 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
PAX2 GDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11731455 22552444
RBM4 U2AF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
THAP1 U2AF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
REL CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 14627988 15922711
PAX5 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21549805 16482219
PAX5 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15676205
ATF1 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12044952
ATF1 ARNT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12527906
CEBPE ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10233885 17347301
PPARD NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17620284 19587222
EPOR EPO â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29997244 20178071
SP3 ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9115370 10374837
WT1 NES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17912546 18212735
TET2 WT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25601757
SIX1 PAX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17035528
PBX3 FGF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10026229
SUZ12 H3C14 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
PAX2 PAX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11704761 17166926
NPHS1 KIRREL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20233749 15843475
SERF2 GC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H3-4 H3C14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
BIRC2 HTRA2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ATM CHEK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 10973490
HDAC5 NCOR1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CDKN1A CCNE1 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 16765349 5218735
AKT1 MDM2 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
MDM2 AKT1 â—¼   PHOSPHORYLATION ✅ 0.81 0.81 mint 5217292 15527798
NEDD4 AKT1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19953087 23195959 31390487
PPARD NCOR1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11903058 11867749 21775429 15001550
PPARG SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 18509005 24735796 20360975 22282354 18310298
SP3 SP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15247906 11517158 10825178 16734381 9329821 12414801 12200149 23825960
HDAC5 MEF2C â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 10737771 23752268 11279209 20211142
SMAD1 NEDD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15231748 21308777
PML PPARG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32929351 20211142
PML EZH2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17560333 27634302
YAP1 STAT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27684187 22863883
MYCN HDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18003922 31856871
MYCN HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31856871 20697349
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
PPARG RARA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 32929351
HIF1A SP1 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
IGF1R ERBB2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17307140 30898150
BMI1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
FGF8 SRPK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PPARD RXRG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15604093 22205725
CCND2 RB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
EGR1 TP53 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
PPARD MDM2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
NUPR1 FUS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19650074 16478804 32780723
CCL5 SDC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 14637022
EZH2 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27634302 27705803
MAX SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 33961781 25609649
HDAC4 SIN3A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17011572 10220385 17210713
CCNA2 CCNA1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SIM1 ARNT2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27472814 32296183
AKT1 CDKN1A â—¼   PHOSPHORYLATION ✅ + 0.83 0.83 Signor 31575057
KRTAP10-1 SPRY1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HuRI 32296183
CDK9 TP53 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
TGFB2 TGFB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27684187 11483955 33961781 11157754
HDAC2 SP3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17548428 12151407 12176973
HDAC2 PPARD â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11867749 25241761
EGR1 SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20121949 12569082
CEBPB SP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16651265 12847250 12665574
EZH2 MYCN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23362253 27728805
ERBB2 FGFR4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30898150 28628118 28205554
HDAC2 PML â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
PPARG SP1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CDK9 RB1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
MAGEA8 ZNF224 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
DNMT1 HDAC2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
ARNT2 SIM1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
CDK9 CCNT2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
STAT1 IL2RB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 10602027
SP3 HDAC1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 17548428 11517158 17906119 16734381 12176973 12200149
HDAC2 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25241761 11641274
MYCN SP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18003922 21123453 20697349
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
PER2 MDM2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34257372 25103245 30425162
HHEX PML â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10597310 16189514
HDAC1 PPARD â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18037904 11867749 16189514
RARA AKT1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16417524 23693014
SRPK1 U2AF2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 33961781 9472028 23602568 32707033
MAPK3 DUSP6 â—¼   PHOSPHORYLATION ✅ - 0.86 0.86 Signor 15632084
DUSP6 MAPK3 â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12840032
NCOR1 PPARD â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
IRF8 SPI1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CREBBP MDM2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
TP53 WT1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
SUZ12 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24457600 26344197 22439931
EZH2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10581039 24981860 21685935 26344197
HDAC2 SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 26344197 20075857
PPARG HDAC4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 12943985 21605119
CDK9 MLLT3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CHEK2 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MDM2 PML â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HIF1A TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RB1 SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AR SP1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
IGF1 IGFBP3 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDKN1A MDM2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HIF1A HSPA4 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
HDAC2 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AR TMPRSS2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
HIF1A MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PML RARA â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
IGF1R MDM2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 12821780 20195357 28092675 18632619 19165858
NEDD4 IGF1R â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12697834 18286479 18632619 19165858
HDAC2 SP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17312152 18059533 16713569 15713621 17894944 12091390 16036112 12151407 21159880 12176973 20697349
SP1 NFKB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18083845 16740634 33572115 7933095
CEBPB EGR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22260630 12947119
RARA RXRG â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
IGF1R MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
MDM2 RB1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PML TP53 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
HDAC1 SP3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
CCNA2 RB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CCNE1 RB1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HTRA2 BIRC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11583623 12865429 30948266
RARA PML â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11050004 1311253 16189514 16713569 16540467 10882117 17560333 18073335 10610177 12935927 20159610
PML HDAC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25812002 18073335 11259576 18644863
AKT1 TERT â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28628118 15843522 28205554 10224060 18775701
SMAD1 YAP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19914168 21685363
KIT STAT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25241761 9355737
HDAC1 SPI1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14647463 16331260 11593411
HDAC2 DNMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23708667 17967891 21670149 10888872
SPI1 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 9478924
HIF1A SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 17024177 17418410 15780936
RARA SP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18270252 10361124 19401466 16713569
DNMT1 EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31130994 16357870 22094255 28068325 21378168
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
ATM CHEK2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC4 MEF2C â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
SRPK1 U2AF2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
DOT1L MLLT3 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
TP53 ATM â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9843217 9733515 9733514
ATM AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15546863 15899889
ATM ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20730097
CDKN1A NGFR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SMAD1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19819988 11786386
KAT7 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22713239 20123734 12609999
SALL2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21362508 19131967 15082782
HTRA2 BIRC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 16713569 11604410 12865429 33961781 11583623 31617661
AKT1 HTRA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17311912
MAPK3 DUSP6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 DUSP6 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 17208316 22569528 20463170
MAPK3 SP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17685427
MAPK3 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15093545
AR MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
AKT1 MDM2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
HDAC1 MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15640443 33985974 12426395 30818224
HIF1A MDM2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12606552 10640274 25447306 15880652 19696166 25535359 17234751 15385570
MDM2 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22869143 16713569 12915590 23169665 14507915 19150978 20972456 15195100 12759344
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
NFKB1 MEN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11526476 16651450 16713569
HDAC1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 16713569 11259576 18644863 25812002 11430826 23563092
SP1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9819401 21360626 24728382 16713569
NCOR1 PML â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11430826 10882117 16713569
STAT1 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21115099 15519999 22589541
TP53 PML â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14992722 18056437 14715247
PAX5 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8521821 22105368 21319196
PAX2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8521821 16320598
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
TP53 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17530187 15456866
KRTAP10-7 SPRY1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
HHEX FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20176809 22844093 22874537
STAT1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18370868 15057743 2606351
STAT1 ETV7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
STAT1 IRF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10092656 16918696 19074829
STAT1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17386941 23922745
EGF STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28542650 19168569 22162832
NFKB1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11689575 17407600 20352621
AR PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11676474 20610535 11745419
HIF1A MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20631454 19285046 19950212
CXCL8 MMP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18660381 17375198 11023497
SPI1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10760799 16707500
PPARG CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909507 20663893 11932328
HIF1A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17273746 11641274 16511565 21148070 24015760
SIN3A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15695521 28514442 9520398 10640275 14647463 12398767 9150133 10444591 14593184 21258344 12943729 12374985 17956988 11102443 9885572 17962807 26496610 12453419 11171972 16331260 20585571 10220385 25314079 12091390 11931768 17643391 11602581 17827154 12724404 11784859 23752268 18059533 9790534 9804427 26949739 24981860 33961781 19182791 11118440 15451426 12920132 26344197
HDAC1 SP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15647279 20072153 19062177 11909966 17894944 21636851 18003922 12176973 11896613 15557281 10409740 11517158 15713621 12665570 15722551 17906119 16478997 18850004 16121030 16883603 12091390 15155736 18948152 18059533 16713569 20385359 15528196 16734381 12200149 12847090
HDAC5 NCOR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23752268 16713569 10640275 10860984 11931768 21081666
HDAC4 NCOR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 23752268 16713569 10640275 10860984 11804585 17956988 27684187
NCOR1 PPARG â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11903058 17468099 10339548 30575522 15681609 15604093 19596656 22078880 35140242 11877444 16127449 30595551 23703729 21775429
NCOR1 RARA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9531570 19377461 10336495 16606617 25303530 21988832 27107012 9121466 10882117 15604093 16469706 30532072 18978041 15336696 7566114 9486655 20543827
NCOR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22395773 20462215
AKT1 NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23940660
AR CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17617741 20610535 22040886
MAX SERF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
PPARD PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20097210 10991946 20176998
SMAD1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23071089 12589053 16580992
HIF1A PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18461556 19490906 11879638
PPARG IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18394717 20064783 20685873
CEBPE SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12032776 12202480
PAX5 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10688639 11179673 21549805
TFAP2A CREBBP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12586840 11694877 11744733
RARA CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23321499 16417649 21110951
TFAP2A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12586840 12169688 17905638
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
SP1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7811231 8524292 11418664
CSF1R CSF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26235028 2408759 22483114 8355686 22153499 22902366
CEBPB IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12574125 10453008
SP1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8454603 23226269
RYK DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15454084 23331499
NFKB1 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18498249 17898080
HIF1A CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21029732 16399861 19304911
HIF1A NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9486205 7500013 7508926
SP1 EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14741200 22138754
SP1 NGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11839795 19114034 21123453
SP1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20427719 20538607 9151857
SP1 HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10558886 10471823 11802722
SP1 KIRREL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19703278
SP1 IGFBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10342835
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
SP1 HDAC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18632985 18850004
ELK4 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10194767 23063436 14770179
EGR1 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9053449 10671503
EGR1 CYP2B6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18303024 19467232
EGR1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15517885 12890669
IGF1R IGF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26027733 21645859 8452530
IRF8 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19103645
WT1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9076342 7791758
AR IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20610535 23859805
HDAC4 MEF2C â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31040226 23752268 32296183 15743821 15964851 12709441 10523670 11504882 11792813 18332106 11486037 11279209
NFKB1 REL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 27609421 17962807 35140242 33961781 25609649 26186194 15143182
NFKB1 BIRC2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 21725609 23178297 23572150
NFKB1 MMP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11376631 19275880
NFKB1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9572484 11243407
MYCN HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
SP3 HMGA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12799440 10471823 11802722
REL BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9372964 12414938 10049645
CEBPB CALCA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19261615 18650268 22905241
SP3 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14567977 14645238
MYCN TJP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16093321
MYCN NES â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15117961
TFAP2A PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7958425 12169688 16790435
SP3 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9415398 11578973 11562358
PRKACA GRIK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8094892
AR TJP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18535113 20610535
AR MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20610535 20946682 17283128
RARA CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11090075
EZH2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21135039 21884980 27338022 18931660 28068325 23079660 24469040 19026780 21190999 26496610 26748827 24320048 33849069 35016035 27634302 29669287 18285464 20543829 18453536 31130994 21123648 20123894 24183680 27728805 25470042 12435631 22939629 16224021 23624935 24457600 26344197 20075857 15882624 23684459 31786184 31281901 23238014 26130719 19026781 27705803 22439931 27303043 31631027 24981860 33961781 19734898 31948940 18483221 21378168
WT1 U2AF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 16189514 9784496
WT1 WTAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17936204 17095724
SP3 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10196209
EPOR EPO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9030560 29997244 9808045 17327410 9774108 26481148 15358619 10318834 8662939
PAWR WT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8943350
SP3 ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11846400 10556032 16132117
SP3 TFAP2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19481140 22827437 14744778
SP3 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11368006 10618488 12440974
WT1 ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10047468 8604351
TFAP2A H3C14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11835395 9776742 11018030
PML UBE2I â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
KRTAP10-8 TGFB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
AR NCOR1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
KRTAP10-7 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
HDAC2 SUZ12 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
DNMT1 HDAC1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
EPO EPOR â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HDAC4 NCOR1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
ARNT2 HIF1A â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MAX MYCN â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CCND2 CDKN1A â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
DUSP6 MAPK3 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
NFKB1 REL â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
ATM TP53 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
IL10 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
HIF1A HDAC4 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 15280364 19071119 21148070 30867818 16951198
HDAC1 SP1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCNA2 CDKN1A â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
TP53 UBE2I â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
KRTAP10-8 SPRY1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CCNA1 CDKN1A â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
HDAC1 TP53 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
KRTAP10-5 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
HHEX KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
EYA1 SIX1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
ARNT2 HIF1A â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 8927054 33961781 24722188
SP1 TP53 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CDKN1A CCND2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 16765349 5218735
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
NCOR1 SIN3A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 17210713 11430826 16713569
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
KRTAP10-1 KRTAP10-8 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
AKT1 MDM2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32450252 25241761 18332867 12145204 19166854 15527798 20856200 11715018 23397142 11504915 11923280 21930127
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
CCNE1 CDKN1A â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CDKN1A TP53 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CDK9 CCNT2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32707033 9499409 16331689 18566585 17643375 10465067 33961781 24981860 21729782 26186194 23602568 11282025 27684187 23455922 11713533 26344197
LITAF NEDD4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 27927196 16118794 11042109 33961781 25963657
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
HDAC1 DNMT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 22274925 20613874 26794444 10615135 10888886 17707923 17934516 15870198 21670149 27593931 17967891 12473678 23708667
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
SIN3A HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16254079 12398767 21258344 12943729 9885572 9150134 12453419 12493763 14749338 22493095 12082111 25314079 12091390 17827154 12724404 23752268 18059533 9804427 26949739 24981860 15451426 26344197
CREBBP STAT1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
IGF1 IGF1R â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
IGF1 IGFBP4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CREBBP PPARG â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
NCOR1 PPARG â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
SMAD1 YAP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CREBBP KMT2A â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DNMT1 RB1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
NCOR1 RARA â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
TP53 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.99 0.99 mint 17139261 5219401
MYCN MAX â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 2006410 23792191 26062444 24859015 10229200 1935896 18003922 18488021 27728805 10597290 29028833 25175806 17289033 20946988
CCNT2 CDK9 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CREBBP HIF1A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MDM2 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ATM H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
ATM CHEK2 â—¼   ENZYMATIC_REACTION ✅ 59.0 1.0 ACSN 11331603 11850621 11877377 12086603 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20723763 21376743 22743550 23847781 24050180 7575488 9407949 9488723
ATM MDM2 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23148884 18619531 22826432 27156884 29144413 29294106 23046908 17609267 18171990
ATM HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 27245613 24681585 21095578 18971907 21095582 27027353 23573973 27068951 25956861 23707302 26942179
ATM TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 452.0 1.0 Omnipath 25301947 21720806 23549171 10713094 16501611 15077171 24886358 17570479 19375142 22028490 16916644 14712210 19303885 9407038 11927276 26700820 28356518 15226429 10723129 19788889 12064478 19705844 26673821 22179422 20931131 19062161 27030982 22891162 17157788 19056039 15758953 12049739 15361830 26620371 25865756 22615843 10196661 10656682 11313957 25088203 15140942 12519769 16319535 24469230 12776195 17234789 27511909 29238697 24608431 12927814 16783362 11875057 16436515 22778557 15181149 12702572 10500142 15178764 28842590 28145533 11591448 17855337 22726545 20206688 26824362 21317290 26104798 24704793 9765199 11314044 16906133 17174997 21593792 17967874 10771484 15585169 19625493 15178448 17596534 16288207 15048074 18353733 24057508 19535302 29344296 23708100 29872395 23705030 25043304 33761896 18431490 21404020 15024084 22559321 12151394 24078877 12080066 33982778 16893723 10958792 18289945 27183917 26337656 29170437 18765533 10744722 21748595 18056442 24820418 15489892 16390936 24086335 28140789 23091651 34523970 32001619 23418564 15279808 21317932 21188172 27559048 16818505 17616578 11551930 19010925 11709713 24711418 28654064 18339864 11173129 17486112 10570149 29774100 18381438 21994612 29558908 15258567 9372954 25860929 16858402 33692124 15775976 34107253 19923893 24958101 10436023 14752509 19962312 19071090 26438152 26093282 20123963 22444248 9843217 17525332 15456784 23533526 11780126 20353948 29290977 11096068 28102346 18855897 20372057 24395704 23890999 15725625 15806145 34103468 18345031 16997395 16293623 28477117 19828454 27630139 12071847 22002314 21315088 27177180 12645530 12890678 26113041 15794754 18560558 22099307 9885574 28903382 15665826 24877058 18332866 10611322 24380814 14871840 19934315 22975381 16489034 18406507 21440540 33687951 10608806 23892398 20730097 16914171 15782130 15177184 22055193 18490454 25867001 24349352 18045533 20663147 17535811 20506250 23982736 22375140 15700044 15279774 19266268 24358288 18697815 14729946 20637859 12242661 12771937 17371838 31940492 19409520 10528155 24037342 17257427 11121242 15310764 23148227 28915641 26928575 21423215 11865061 16949371 27810895 18449195 20711232 27389279 22213803 16713569 10446957 22797063 16478990 29048667 15489221 17241873 21187893 21441950 23907539 20005840 9733514 26244501 21614094 12082529 10467728 10714958 32061892 16636671 29147215 10673501 12091386 25202122 21465263 19544417 25823026 24078903 24038750 22198295 21480565 15177039 28182994 28208785 18674635 20183804 18818083 9925639 17712528 15254178 11483158 27940348 26675349 26261212 19717643 12606585 24559687 14871926 23150668 21329876 28153791 12518062 12767922 23824039 11711532 19251701 28118604 15078887 12393500 17456577 20976220 23380594 12519780 20810927 15533933 22420423 17108107 20145032 18032786 18785202 22037398 23184057 31968249 16729035 12588868 21614932 11546806 18614045 14757188 15029243 14968111 22649771 25512053 34496248 18604166 17609585 17976513 16223874 25433195 18985806 9363941 15159397 34282274 29301278 24505404 26056062 23577291 18272544 18715874 19536869 29334356 10801407 15155458 25201202 24376853 19907922 23525106 14643431 28340339 28051100 19085961 15212693 22201816 20026654 16322229 20080565 9733515 15632067 18672098 22577550 25691451 12637545 12548019 11672523 26984736 12324477 16552184 22084686 10864201 14744854 21532626 17118344 19482562 9561848 12511424 17668048 23358251 18511169 21460853 22022355 12939400 21415014 17292432 25651062 23168260 12111733 16648554 30361254 23678107
ATM SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22588298 23277204
ATM CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 176.0 1.0 Omnipath 26683224 17303408 28852018 10713094 20080130 27545311 9488723 15342622 23941746 26485758 28937603 15279786 24882580 10744722 15125777 25746763 18583988 28051860 17570479 16531125 21329876 23892398 19607708 16940182 26643553 20396397 28259974 25361978 17660363 15459660 19375317 25247188 16311512 23118481 20498628 22030216 25613496 22420423 9407949 17918214 12493754 20859824 26158765 15700044 27558808 11901158 27602502 20637859 16163361 20599567 23638118 16481012 12242661 23847781 12024051 15140942 11728459 12454775 16936775 25450480 28950914 26295265 20160490 22319212 24349411 18006705 20723763 18678890 12805407 20860841 23386996 24050180 11668173 27271602 29304495 12447382 24798733 9889122 23347679 18794134 21147465 21421565 26516160 17715138 21376743 19440053 12773400 10973490 17174984 26442630 15694385 11877377 29022904 18809224 11850621 18787700 12718885 19481982 22743550 20372057 15212693 16085488 19101576 29555944 25954303 24473398 18087292 16794575 24492479 24244353 19793801 25404613 21102523 29156743 23253087 16997395 7575488 25808488 20647331 18584027 21851590 21315088 23705030 15629715 29741650 21772273 11025670 18590585 26610585 15964794 29434792 20068082 23006513 19881958 19230643 12607003 24769180 25249630 15024084 19772495 25714019 18603484 25173936 23666059 19473886 27568553 22808196
ATM MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 66.0 1.0 Omnipath 14654783 12383858 17936559 20651945 17303408 19816404 10611322 23150762 23277204 23386996 26416444 27258263 23002429 11331603 15865937 21556066 16163361 23708100 17570479 20514355 22264782 27177180 18265945 28690977 23847781 22264786 15140942 15964794 19788416 22624716 25201202 27462439 12607003 28050229 32350255 22649771 27956626 15459660 22976441 25247188 28904407 11877377 21859827 24534650 23405218 29290977 27568562
CDK9 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19914168 19914161
CDK9 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8870681 12037672 8170997 9258347
CDK9 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 24173284 9372954 11483158 9315650 19413330 19664995 23603988 24202322 11709713 16083285 1088347 16552184 10884347 24286312 10747897 17942552 16741955 17287340 92065884 12064478 10348343 14702041
RB1 CDKN1A â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
NCOR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 22253232 20466759 20696891 24821728 24821727
WT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10224085 18202757 17160023
TFAP2A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 21084835 9473523 16867219 16288208 11420667 18955504 20805990 8988173 17875680 12226108
SP3 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 10649433 12434298 18850004 7499379 10625687 11064455 23401853 16103879 19584258 12151347 20301197 19197985 15790310 12773551 8995437 10485470 23676218 12379120 18628250 16810128 16533812 23066038 9819384 10321829
TP53 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 389.0 1.0 Omnipath 9349504 22270849 8749722 21242964 22290440 23874636 23349794 23650552 17280505 16288208 19882681 22948151 8641969 18840648 7777546 9360984 9707425 14614448 15586362 12889596 10597242 18719376 17938176 16343438 9916993 12806965 15024021 10037739 19394332 19749793 22480684 15136035 19501055 22732402 15988033 17307334 18272192 23665236 20331637 10435630 12239594 14743206 24599959 9714336 9652736 19954840 12392301 15339933 9154806 19383287 21295542 16894028 23187802 15248906 14522900 18483411 16261158 11892838 20190809 17167174 18615633 15790310 17916908 19472317 12717415 19789303 16317118 7696178 24584189 22989750 18573881 22532570 9288775 16103882 11890931 17646389 17344317 10753197 8557703 15872011 24356969 11278953 22279545 12902982 9920903 18644983 21524151 16540664 10935506 16537920 19843844 9535786 17878219 9405685 10749849 18656471 11021966 19723072 16778363 18628250 16557594 9614553 21791610 10072388 12203124 12420214 12640112 16601686 20531308 15741235 17317670 18446786 18505818 9224526 17569660 21900401 14517211 12934105 22713239 11313928 15492238 17509529 15985438 14722112 18755897 15489892 23759594 7624148 17786325 9223430 24074410 9525742 11395510 21317932 11444825 18645021 15856024 10559267 18593586 16970927 12665570 10101800 23017582 20696891 9268733 22001409 24821728 23146670 22427654 12573582 19118657 11973611 24096481 20797428 17685229 23066038 10029406 12681065 12433990 18769160 15208672 11152513 8547219 15851483 23474493 24384472 11175333 17158927 23100276 17762884 18951877 12045203 15051477 16107883 18521083 23159636 8603071 20814747 15082782 11375890 21084835 10348346 22244155 21325288 12379483 14580351 17592775 8910340 15566940 12173040 12007564 12609999 8878553 12080472 12384701 22266868 17404570 23329847 7478511 15067082 15007388 16458891 9268365 15728246 17224908 10094833 15897882 18059034 11739748 7624134 17146435 18690848 21528307 21546904 18208621 18172861 17977830 17721438 20817677 22894933 18225552 21642427 11162600 9183012 8647846 10660101 21858218 22514644 18451802 11384995 20673369 7774811 20187950 16230382 17339230 12168779 19630958 8242752 9895308 21606339 11748232 16410722 22611192 16061648 15009091 22503977 8799837 15660129 20473858 20448457 16488074 14612423 21903579 11668476 11313463 17101782 19067706 17121856 10792001 16341121 12925527 7566157 22190353 12782287 9233781 15509808 21245169 17145718 24134839 10498892 18094076 14635196 23208500 20843368 10327058 21969549 9440695 10625687 20885946 12851404 19846554 10910098 14614455 18419600 21552844 24835508 21541551 9472102 11922774 19244234 17903248 9216067 18193090 10566557 18757425 11429705 19608464 8632901 8691637 15184659 12716906 15259070 24559687 7970699 15738655 9588214 16574813 15302882 12560513 16131836 16778203 10522058 11032828 9816111 9108440 15860260 17108107 25024194 9582019 22266186 20036872 9926942 15710329 19243472 17997002 19435914 21093383 23149933 11162506 17678435 11895854 8616838 12748190 17610896 18269916 22086179 21557991 17942917 24821727 11557753 16204065 18645003 24205274 9816061 12226108 24379401 15539944 7753560 15371422 10799578 10777217 16434701 17996705 21957244 9191059 9519881 9207798 24289924 21733196 15496412 20124454 20153576 22172947 10321740 21715977 22253232 8816885 24189165 15882981 8752276 20511722 11514734 20962589 12869419 16733561 19713748 16931520 10499591 16581545 19738071
AR CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 16281084 10076995 11606392 10606230 20610535 10809237
EZH2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 21572997 21546904 24074410 21629038 22956625
STAT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20738848 11162600 12239594 16449678 21307941 22591439 10023678 10866323
HDAC1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12665570 19182791 15130752 18210215 16287849 17172847
RARA CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10356361 24821728 21383775
HIF1A CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15071503 15190211 10559391 20043814 21362093
CEBPB CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10982390 15466360 15041706
DNMT1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21229291 21572997 19056828 16276353 9588214 21868513 23658227
EGR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18316600 20368687 19508870 24384380 17307334 11502738 12690110 21642427
PPARG CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19551868 19103521 19208833 16985067 18509005 15041706 15345676 16091736
SP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 9580699 15978937 15557281 11064455 16103879 19584258 20301197 20935676 15961274 15361832 11274368 11842244 15489892 15302882 10212208 12796485 23184467 14529564 12806965 9819384 10321829 10649433 12434298 18270969 18850004 16081043 9183012 21858218 10809237 9618481 16298343 11574165 10362258 11384995 15659839 14744793 10030670 17090534 10733944 19318349 12665570 18202149 17516505 15033443 22001409 17885207 10485470 9553133 15345676 15694838 22427654 17556661 10506225 23066038 15979845 18636159 14527674 24821727 15899840 14755691 12151347 24589735 18210215 23877711 11953011 21311948 15528212 15790310 10878024 22132221 12782287 12773551 8995437 21184768 12379120 17026958 24451377 10601254 8557703 16810128 16533812 7499379 10625687 15389873 16706751 12727210 21325288 16818630 18419600 15041706 23235480 19244234 15694666 23329847 18509005
TP53 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 19922265 12897156 19597488 16616141 28433629 20066118 20457558 19749794 6396087 21163364 17371838 21900206 21340684 25241761 12897801 12748190 20182602 11896572
MDM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17373842 25241761 20086099 14633995 14761977 20308078
AKT1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 11756412 11923280 16697215 20452955 27603133 20398329 18372248 15001356 15808505 10217147 19440234 20138985 12431783 10753973 17855660 19216069 28358423 20214616 11463845 9829964 17570479 17646672 16680151 11231573 15169778 12851486 31575057 25241761 23109003 21933447 10949026 16775416 23886938 26436589 16288292 11715018 16055744 18636226 15023346 9812896 12042314 17680028 24848107 16982699 11779850 10722653 20832730 18570873 20307683 34069970 17052453 15798220
SP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17026958 9389648 9618481 17550342 12545156 11013220 15155580 11074002
HDAC4 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18632985 18850004
CDKN1A CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 23443559 26186194 25241761 27107012 8756624 15169570 25416956 16765349 31515488 16189514 32296183
CDKN1A CCNA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12383116 25241761 8756624 29997244 16982699 7478582 10022926 32814053 15232106 16009130 16189514
CDKN1A CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 23443559 26186194 21308745 9660939 8756624 15890360 9380407 8242751 8662825 12947099 9632134 17679094 26496610
CDKN1A RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10498883 9315635 17303408 10486249 16236519 11520855 15279786 9190208 7575488 10385618 9736735 7736585 19075565 18590585 20068082 9425340 18786381 17660363 10778858 17556661
CDKN1A CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 23443559 31831640 21988832 9472014 17293600 11438644 9380407 12839982 16765349 9632134 25241761 8891332 9660939 8242751 9218599 11477082 8756624 8662825 8637717 9716181 13678583
CHEK2 TP53 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10710310 10673501 10570149 10673500
TP53 CHEK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15326376 19435816 10531348 19395378 15044452
CHEK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 18778462 25545885 16893723 15254178 18833288 23892398 12052256 18319725 25372714 15459660 20514219 25174607 28140789 17339337 22420423 18566216 20950777 20651945 15810020 15700044 22891162 17157788 11551930 18725978 10724175 15467443 23351141 20096447 11063934 11709713 15659650 12242661 10656682 15140942 20041275 11728459 18614044 12781359 22649771 18812180 11173129 10570149 15279785 20081365 20860841 11875057 22778557 19923893 24553354 22797063 26384650 23316480 15489221 19788416 10801407 21187893 9843217 9733514 10710310 24358900 21526939 23843721 29805302 9733515 25404613 12548019 21625617 10673501 11447225 17118344 26610585 19544417 28038466 12810724 25823026 15024084 17464182 15862297 19933256 20526329 12111733 20183804 23144912
CHEK2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15862297 10710310
CHEK2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24466208 17380128
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
EYA1 SIX1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 15492887 28514442 32296183 11734542 12874121 33961781 26186194 15226428
SIX1 EYA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17035528 15226428 15492887 11734542 32296183 12874121
HTRA2 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11604410 12865429 11606597 16713569 11583623
HTRA2 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11606597 12865429 11583623
KAT7 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15507644 11006273 14966289 21632823 11747826 17720252 12748286
KAT7 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10930412 16713569
FGFR4 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
DUSP6 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12840032 23331499 8626780 8910287 9535927 9596579 14690430 9922370 18988627 17322878
MAPK3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 16009338 12213825 8384717 10995751 12048245 15878863 19327116 19443782 15212693 15367685
MAPK3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 32205409 20150555 21983342 11904305 14593115 18199680 8226933 14744793 16079281 19318349 20882567 22266860 28574228 21097497 8388392 32615164 16377629 19245816 18775330 9604935 15212693
MAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10781582 11239457 10958792 28937686 9467949 10348343 24194938 9739174 16713569 12955074 10747897 17237827 25767119 18523266 12393879
MAPK3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10551817 18519666 24099156
MAPK3 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 25241761 15616583 26769850
MAPK3 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 10197981 9335504
MAPK3 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18596912 11733495
MAPK3 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17804409
MAPK3 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 9020136 9130707 26028036
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
AKT1 MDM2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11154281 11715018 11923280 15169778 17680028 20214616 20398329
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
TP53 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 201.0 1.0 Omnipath 23150757 20948295 10871862 10914734 21422812 21957016 14532965 22290440 20663877 20547751 11591713 24339722 11840331 22223137 16492744 15843377 22948151 7888679 20156675 21217645 22180176 8319905 9707425 15831521 17690113 9649502 10688649 9194564 15917661 15090541 20837136 8187772 10788589 17907153 15192123 8440237 11964305 16510138 10856296 15580300 7624148 12208736 21211512 16624812 17848574 11245471 21637567 20588255 10562557 9525742 9270029 16479015 19941079 14602726 15024021 18814047 20036872 10718212 18852133 12374749 18397889 25016801 12755686 22081073 22245141 23365201 8957072 22197810 15856024 20703075 23483203 9645455 19648117 20331637 22301280 14743206 23982177 9486848 15734740 19638633 19671680 17310983 10469568 20659896 10072445 21097889 17237821 11748232 11085543 21750655 16337599 21295542 1614537 9815889 9070662 16585169 9472631 17936559 17139261 11328884 12887889 20858413 9858609 14610316 20080970 19505873 11313463 15684615 18359851 18783169 16202543 9267820 12235242 14990790 15851483 7587074 18336191 21478269 17043642 15361831 18025460 23612020 10208414 11756653 24389645 9071998 9430645 9400998 9371494 23149414 22532570 9271120 10777217 22383580 18781178 12606552 14514686 17318220 11127813 16571800 19085961 9207798 10891494 10065155 11593391 14570892 12902982 19649205 20124454 17390010 19955655 12138177 19663772 23581014 15908423 10321740 23150759 19837670 10348346 18632610 9294611 11956627 12750288 12851404 8313378 9135153 15735665 7958853 8247544 9535786 16501602 18566224 8910340 11046142 9405685 7936649 12173040 17329361 21451571 14704432 23874713 18333294 19541936 22787160 18585004 22085928 12080472 7651818 11179471 10949923 19428175 15592502 8413278 11714701 10566557 18583933 9681831 15550242 15007388 19590512
MYCN MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15917661 15644444 15927364 19649205
UBE2I MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15169778 15340381 15147722 12820959 10722742 19459846 18006823 10721693 19440234
AKT1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 11756412 11923280 20856200 20452955 20398329 18332867 19664995 10217147 11154281 19216069 20214616 11463845 19166854 15527798 9829964 17570479 16680151 17646672 12145204 15169778 15140942 25241761 11715018 25209720 17680028 21930127 11504915 29311840 15574337 23397142
MDM2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 559.0 1.0 Omnipath 20657550 30005830 17616658 9529249 10321734 33650658 9724739 24462112 24621507 15933712 23826318 24667498 22948151 22653443 23776060 25313037 25241761 19303885 16857591 23246961 19033382 20591651 21149449 25417702 15122315 16579792 27543608 29670376 12208736 17848574 26673821 25277184 23443559 23318437 21060154 15210108 19805293 8875929 8058315 21471462 17879958 25362358 23169665 22301280 21584881 20124408 10980696 26876197 17310983 17380154 15058298 24567357 18665269 30109812 25637791 18467333 22337874 22227409 22389628 15242646 22510990 15950904 15001357 19483087 26540344 14559824 21986495 26556313 20708156 19901969 33765973 32528731 11562347 10202144 22374672 10722742 22083959 21965653 17098746 19234109 30679555 16107876 12690203 22525275 19071110 28542145 12620407 20837658 27129163 9131587 24240685 27031960 10681559 19305137 11744695 19188367 16023600 24659749 17347673 12944468 20395212 22084066 20639885 21454483 12897156 16432196 10347217 10706102 11178989 20174603 16751805 15542844 12842086 11431470 11384992 25739118 15064742 23402884 27462439 16905769 22124327 27215386 12867035 22588298 27336364 14702041 16152627 23776465 22262183 21132010 19411846 18309296 23483203 11709713 18981217 14612427 22920093 23671280 24980433 27905468 25168242 21750659 26238070 22737255 23609977 27282385 20847049 20705607 21075307 28082682 17297477 11697899 17936559 24361594 19098711 15469934 34591612 24998844 16212962 11094089 12915590 17116689 11713288 15144954 23201157 10608892 17591690 25156994 17301054 22444248 26883110 26001071 19160491 22157679 24413661 19357310 23802716 15280377 21317885 11597128 19579266 25624478 18061646 21088494 9223638 10435614 31177307 11331603 22391559 20570896 19941302 9278461 18485870 15604276 18566590 12612087 11046142 14704432 26186194 10935507 16173922 14596917 17159902 25543083 19656744 15848166 18316739 22266868 17056014 19255450 21561866 19590512 11839577 22991965 22266850 24200963 11285227 11713287 22975381 19081178 20660730 26475964 16678796 23261415 20173098 17666403 25464845 32427887 23252402 17438265 20959462 22659184 17470788 22912717 17080083 15247280 19332559 17989425 16870621 18813780 20235143 11278372 10562557 25609649 10561590 19411066 17908790 19568783 7926727 21925390 21988832 24127580 18604177 14499615 17371838 17525743 33061576 21887275 26578655 21084564 16861890 20694676 12552135 22914926 17363365 24643130 1614537 22916255 12381304 34992144 12167711 19857530 15053879 10889512 11486026 22103682 16713569 17110336 17426254 10640350 21316347 21478269 15154850 12529318 16595680 16414131 19597489 23880345 27893708 7686617 27811966 17318220 29997244 27308622 19166840 35044719 16159876 24314634 15313915 25283148 22032989 24926618 18172499 19837670 16215989 23134341 26908445 9824166 18451149 21170087 23572512 21465263 22807444 15013777 16845383 10488081 23946421 11714701 25384516 22474335 25312347 23370271 23150757 18541670 22318540 11925449 21572037 24488098 32066565 17268548 20542919 11572869 16338390 21857681 23150668 19223463 20234175 20484049 11070080 20591429 22575647 11351297 16624812 22411991 20588255 17369817 11223036 15908921 9582019 25103245 17302414 21071676 9450543 31968249 34562520 18332869 14671306 21084285 27856536 30464405 26882543 21726810 33020477 21261729 21268072 12426395 16964247 20659896 19106616 22331460 23728348 10827196 22524527 21098709 9363941 17139261 20080206 14517261 22487680 31652301 17290220 27106262 16866370 24207125 28223335 9271120 15550400 7689721 26350565 10196247 27807478 10766163 15558054 35371302 26203195 29487367 25512388 25954860 18223694 15824742 24842904 14741215 16055726 22085928 32894144 18234963 17875722 18815136 15295102 15308643 15358376 22819825 15094782
MDM2 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 15880652 25535359 12606552 25447306 17234751 19696166 10640274
MDM2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16374512 21990374 7791904 28615518 33185004 20871633 10078201
MDM2 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 25241761 28092675 12821780 18632619 17303558 19165858 36042202 20195357
MDM2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17974989 26411689 27835608 26973243 15640443 12145204
MDM2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15195100 12759344 14507915 16713569 12915590
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
MEN1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11526476 16997566 16713569
NEDD4 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 18988627 12697834 19165858
PML YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19788416 19111660
SP1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 24074563 19843528 19047367 15951564 10778946 21536653 19287963 12019268 11452025 19360348 18365874 14577922 19318640 14611815 12368233 15226182 15656906 21553143 15067344 21132266 11342218 16452190 21590772 19649288 17141225 12151407 16234237 17325661 18093727 19106100 18754863 1236823 10637317 21693539 22554713 19912441 11279234
TP53 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15656906 12807729 15067344 15734740 11064449 15262117 16234237 10778946 15371422 22496369 18754863 19649288 19787269
WT1 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12807729 22654424 20842112 10601322 18754863
SP3 TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11342218 16452190 12151407 19047367 15951564 17548428 11279234
HIF1A TERT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18754863 15048086 17699105 16961934
AKT1 TERT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 25999477 22366458 10224060 17570479 22902867 15843522 18775701
MYCN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20811720 11107122 10050884 21862876 20145147 19885598
EGR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9242687 17822668 15958557 12755686 16990849
HIF1A TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12542982 17390008 9537326 15780936 11696352 10469629 17236590 20706634 15629713 11007955
NFKB1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10348347 11032029 8051093 12145335 20097177
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
TP53 FASN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12734185 19861536
TP53 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 15131018 11001824 12089352 20633551 24205274 17097318 10023442 17600529 17014845 8710868 12444079 16181796 22033326
TP53 LITAF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10321740 21836606 17283168 15197774
TP53 GHRHR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10529175 24297337 11852084 24737129
TP53 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17311279 15899818 17077165 18635530
TP53 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17202838 18084622 18945670 11504717
TP53 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16931621 8270002 9275177 19671680 16571800 8641461 9360984 21952947
TP53 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12631625 18281476 18174288 21460853
TP53 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 10101800 23810988 15661074 7566179 15713654 18084616 9525742 20003326
TP53 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11131279 11092782 9194524 8637893
TP53 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12732139 10618379 22264233 23706820 14514686 8183578 14761612 16138117 18593586 23063463 8119773
TP53 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 19846904 15790310 11118296 11384995 21611785 7478550 15967108 18419600 19244234 9865734 18769160
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
TP53 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16432214 20080630 17242190 20422012
TP53 FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17196791 9889415 20393600 9841917
TP53 MAP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10521394 10446979 19411072 10990460 8956998
TP53 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 11850820 10029406 16931621 9774636 8845569 8270002 11244564 15618023 12444079 12749855 21496227 11818069 15827088 8720930 1608930 8119988 23474762 11121443 22729911 22894933 8355507
DAPK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 15355354 17297916 32266931 26626260 27753536 15254178 27681874 22112863 10734067 11883897 21386980 22815859 20851891 11244509 10733583 15542844 26742101 10673501 12091386 18246126 25584963 15489221 20959462 11258706 10801407 10606744 11707453 17339337 12111733 17977830 25229255 34168813
WT1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16713569 10744705 8389468
HDAC1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 10521394 11099047 22266186 20633551 18765668 20075864 17827154 11313951 14976551 25241761 19303885 12426395 19011633 16697957 16959611 16107876 10777477
EGR1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15225550 14744935 11251186 16713569 12384981
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
CCNA2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14640983 10884347 16713569
TP53 IGFBP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7566179 17409411 18431400
TP53 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9537326 16713569 12124396 15629713 16882692
AKT1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 27979972 25360797 26804165 28273460 25751140 24101154 25751139 34052254 25362852 28114269 28793266 26265440 31239271 25601544 28474680 33630828 26119935 27144834 27425596 25531778 34206989 34465890 21945154 25195862 31792377 18640976 28775168 32015438 32523092 22234184 33536280 33622361 30600590 24362629 34155345 24658687 21060948 33162394 20153295 26668327 21730131 26549256 21666719 25605730 26039999 34226698 20823509 34516278 27033705 32064037 32271880 32513743 33990468 24812269 32053631 32929029 34058200 25772246 26364602 27765911 26678338 27979971 33552953 28171658 34129887 21376238 28416665 25998128 25109332 12535517 31988076 26933062 26598551 25373897
YAP1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19914168 35044719 23431053 21685363
MAF IL10 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 15749884 16713974 17404308 20547845
CD14 IL10 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 11274345 11964313 12620219 12682231 12907458 14607900 14660645 15749884 15749903 16127449 16243976 16413922 16713974 16878026 17404308 17485448 17704786 18633355 20547845 21372296 21826665 23508573 23681101 23811849 9743347
CSF1 IL10 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11306493 15749884 16713974 17404308 20547845 24669294
SP1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20072143 22469463 12493739 17376198 12847250 19564345 10903771 10657644 18843277 21309719 10861063 16871431 19307576 11278848 22940633 16413748 17202341 15972681
NFKB1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15465827 9310124 19124729 19766270 16835236
STAT1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18292493 19703987 21398617 19124156 20709027 12817009 21041726
CEBPB IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24715531 17525287 12493739 12847250 16413748
MAF IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20676095 20676092 19564345 28166218 19414776 15749884 19090621
SPI1 IL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20072143 19592658 18843277 12424622 25567680
IL2RB STAT1 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10820393 12811837 14607946 16212621 16815076 17398124 17459805 19833085 19913445 20007590 20856220 21307131 21840487 23124025 24829413 25582338 7512720 7521688 7523571
CSF2 STAT1 â—¼   ENZYMATIC_REACTION ✅ 17.0 1.0 ACSN 11015446 11306493 11777960 11867689 12393492 12811837 14610620 19833085 20406969 20805416 21765015 22323450 22869907 23046136 24030977 24091328 27216177
STAT1 CD40 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 CD86 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 NOS2 â—¼   ENZYMATIC_REACTION ✅ 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20637660 12162464 12417260 16318585 14722242 10882409 24014650 21430289 18656624 10848596 23419754 17997753 12586443 24248598 16284791 8995425 11438703 16140971 17689680 20510882 14530341 19029990 12902503 20889505 17158780
STAT1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20006573 10403401 17660512 10823830 16020513 17507688 15182726 16571771
STAT1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15247301 18028425 19965686 10817568 19616522
STAT1 FCGR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 9748323 8830676 8483949 8647290 12130529 14734612 9551929 7995951 16516295 10820245
STAT1 CSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22951020 15624698
KIT STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 11839738 10918587 11447289 11997436 12040186 21135090 15173823 7543024 15322115 6321473 11294897 10358045 7690989 15567848 19568798 12637327 14585353 15199124 17496910 11438544 25241761 10748192 7657660 12817007 9355737 19615955 11152457 10982844 7592750 16488589
FGFR4 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 11839738 10918587 11447289 11997436 12040186 15173823 7543024 15322115 6321473 11294897 7690989 10982844 19568798 12637327 14585353 15199124 17496910 11438544 10748192 7657660 12817007 9355737 19615955 11152457 15567848 7592750 16488589
IL2RB STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16189514 10602027
STAT1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15695802 10848577 9773981 8848048 9037008 16481475 15894584 8986769
EGF PLAU â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 12094222 15003992 15175028 15466195 15958574 18423981 19631971 20430953 21098712 8101258
SP1 PLAU â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23978400 10361124 21567400 21076612
AKT1 MMP9 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 17409395 17680028 18471976 19440036 19930715 19945467 20214616 20398329 20609352 21084277 22131018 23572150 23589069 24030100 25136802 26597054 27328425 27510662 27572739 29556339
IRF8 MMP9 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10734131 11672593 11875494 11964313 12032143 12417340 12811837 16243976 16413922 16597464 17404308 17485448 22461508 23390297 24091328
SP1 MMP9 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
NFKB1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 18298869 12105194 11376631 14600595 17673602 17922642 15605368 14755547 20332461 18357389 17186550 11060311 18566231 9679762 16687076 17121934 18843978 21963718 18056465 20103608 17174275 15536164 19303700 17158602 7860222 19539355 9500201 19783786 18567920 15175338 17498959 10359016 18801463 19454280 19662350 12193473 16014933
PPARG MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20021931 22472882 22207709 9665460
SP1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8226872 24755270 18028425 9514098 9520415 23799155 20529870 21840940 7860222 17049831 21963718 18357389 9150367 11060311 19616522 11830485 9748266 20638438
MMP9 TGFB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10652271 21900405 25241761
CEBPB CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11937564 11413310 12388374 16239564
REL CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12820969 17705131 11259372 9120310 20058312 16707500
NFKB1 CCL5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 12820969 11413310 11478739 12122011 17065335 17510282 11700023 15144466 19786024 16707500 21189258 12388374 15972972 9120310 11389171 12050170 11259372
PPARG TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 14702344 17625041 31023188 17995524 16321227 18615188 14693716 12711314 16611854 18991162
HIF1A TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16896927 17053163 15611046 19211927 21209004 21057546 21055290
EGR1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17916653 20417179 8794351 8058069 8051207 26279418 10783396 16138117 8876223 20690147 16702209 11707452
SP1 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 12186868 9580699 2808430 12615726 22415074 27974707 12138160 10964912 9242631 15178441 23437118 23936544 11114293 8325508 16714330 11278686 10212284 9837963 11054406 23806282 15979845
PRKACA ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21224395 20166139 18578522 23979717 31562188 18583710 18707149 17603879 19401330 12837751 11533025
MAF ITGB7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14998494 17490615
UBE2I HDAC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11960997 12032081 15199155 24068740
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 SIN3A â—¼   PHYSICAL_INTERACTION 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 SIN3A â—¼   SHARES_COMPLEX 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 NCOR1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 15465827 16127449 21234400 22796940
HDAC1 SIN3A â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
UBE2I HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12820959 15340381 11960997
HDAC1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 11994312 16713569 15640443 12612053 10428808
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 SIN3A â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 SIN3A â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 14673164 15465827 17018611 17563753 21234400 21577210 22514743 22796940
SP1 KIT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24008320 20833840 9834219
TFAP2A KIT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20805990 11310795 9687504
PPARG NCOR1 â—¼   PHYSICAL_INTERACTION 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
PPARG NCOR1 â—¼   SHARES_COMPLEX 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 NOS2 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
NCOR1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20462215 17400812 12392082 10612426
AR NCOR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15598662 11971970 16469706 14593076 15256534 23518348 16713569 12089345 16914745 20812024 20974212
NCOR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15175761 11877444 15604093 16127449 11903058 22078880 23703729 9121466 21775429 17468099
HIF1A CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17082639 19491109 17488804 21925595 23144021
PPARG CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19395102 18485432 20107546 20554962 16303327 20889551 15331599 12695526 15720834
NFKB1 CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 9510190 12058956 11973337 18786178 17045242 15289496 16701870 19376732 19837667 9698090 17276517 11512674 19786024 20038977 10202011 15057743 15517885 12643600 11342414 7876168 15350531 18034886 11716760 11564889 11864912 12218154 12707271 10969814 12748173 14631383 16325549 17586662 18996370 19732956 17041011 10530453 18281166 12716652 16418726 12485925 16004996 9388261 8878392 17917246 10975857 10745031 10928981 16553947 16818736 14670967 18435575 12038622 15958549 17040605 8413215 21255844 22340043 1401924 9452482 16764699 11297551 15950427 15387324 15879558 16105834 11953364 15688424 18074095 8413306 11096450 16803583 10506755 11120852 10477716
CEBPB CXCL8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 23051921 10775602 17135982 8969274 17997161 18512730 21471847 24554449 14645117 15085176 17845418 12707271 12748173 19489038 22031759 8234276 19064995 8207232 16989899 27856305 11991987 19109189 17471497 19786303 16809637 16818736 21255844 19734226 24038085 18772138 19805069 20861254 18487355 11390611 15688424 10462040 16803583 8999951 11120852
MAX ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9294616 9343440 12565711 8637719 19578763 7822433 7478599 8356088 18806825 8262968
MAX CCND2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8425218 15121849 2006410 17873522 21406394 12584560 17558397 20551172 15814658 16908182
NFKB1 FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14563113 12655294 15160330 16770006 10671224
SP1 FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10075666 20617570 11254710 11053446 14563113 10754388 18293083 15659839 11970950 12655294 17192273 11745351 15173177 15004200 10671224
CEBPB FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12496392
EGR1 FASLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15155664 14563113 19032775 9915863 11909874 11745351 15173177 23832418
PPARG NOS2 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11399519 11875494 15644117 16127449 17260466 17681149 17689680 21234400 23390297 6357187 8871614
CEBPB PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22473998 23934183 7557387 12524424 16431920 22610404 15110775 18694725 17242167 16054042 15158467 9950217 10862621 20829347
EGR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 29212876 12011097 22455954
PPARG CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19466435 16306131 16723090 31023188 18274641 19902320 11590167 18991162
PPARG NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15950726 11595817 19997048 10848596
PPARG SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16269451 15111490 15908479 11777901
UBE2I PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19692572 15507114 26192107
PPARG RXRG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 12615696 16189514 18988627 15130092
SP1 CD14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11698458 17203216 12213324 7512565
SP1 SPI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12706891 22734486 10446912 7478579
SPI1 FCGR1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12393465 7869026 8035786 12130529 15304324 14734612 10820245
SPI1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10823830 11481336 14962802 19801646
SPI1 CSF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17116688 8264604 9506963 8302571
SPI1 CSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8622667 25574134 9632776 9988737 12130514 10080908
SPI1 ELANE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9689920 8756629 16247445 9192779 14732495
SPI1 CSF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12130514 12958595 10677505 20864248
SPI1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 10801783 11359842 7799967 18173740 18566416 9376596 11823535 19423615 10328874 17283046 10453013 16439360 17386941 7609733 12061786 9360994 10490619
SPI1 IRF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10570299 9593745 10734131 17386941 11483597 17200120
HIF1A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12542982 20547241 17452336 15907483 19489936 15342390 15184875
CEBPB CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17067998 8654374 10818089 15722556 15388792 17599912 12857754
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
AR CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9822653 15350180 16492776 16344550 11161315 18819102 18031230 20610535
CREBBP AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 20541699 9822653 15691881 12810069 9482849 16713569
CSF2 HIF1A â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10426994 11015446 11280761 11460167 11777960 11907067 12193690 12907458 14660645 15536084 16713974 17301840 18264787 20805416 21133840 21232017 21765015 22869907 24030977 24699077 24958845
NFKB1 CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9190901 11418664 12760745 8135780 8934574 14741709 18285351 10608823
REL CSF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9414129 11418664 8152309 8662666 8934574 8660380 9185524 24899500
CSF1 CSF1R â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 10705574 11306493 20644254 24669294
CSF1 CSF1R â—¼   PROTEIN_INTERACTION 4.0 1.0 ACSN 10705574 11306493 20644254 24669294
SP1 CSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 8107489 9819371 8407965 8981362
NFKB1 CSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18566389 10919279 11949945 7583532
CSF1 CSF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 7883784 8355686 1702217 22483114 22902366 2408759 26235028 22153499 24890514 26095744
IL3 CD86 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
IL3 CD40 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15034038 15549123 17200410 23026134 23125331 23762788 24778133
EGR1 IL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8035792 19426596 18928619
AR CDH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18535113 17297473 20610535
NFKB1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 17272744 18393939 21725609 23178297 23572150
HIF1A NOS2 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
EGR1 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18506761 20448047
HIF1A EPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 16189267 20404921 15838297 21212189 8089148 21054399 10559391 11001829 8756616 20043814 8660378 16684536 16281953 8260699 10207038 8900415 11914036 10477681 11707426 9235919 10202154 11812905 18423195 21309574 15347669 15315937 11971899 14741200 9236155 7836384 7852211 17712557 9654078 24023421 10837481 20631191 8663540 10415537
HIF1A IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15695372 15968405 15930297 16682453
HIF1A MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16099863 17028975
HIF1A CCN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23530034 20450254 17034590 15315937
HIF1A IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20865400 17548584 19490965 22964004 24352507 25750431 16504308
HIF1A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19144925 17220299 17488804 14726529 15277220
HIF1A HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15794924 14726529 20068160 18844219 18683594
HIF1A NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 25156364 9486205 16306444 20079239 16325051 11325839 10679484 12154035 9115299 18339887
RB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15674338
HIF1A FLT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 7539918 1823643 12829734 9159130 13130303 9746763 12080085 11566883 10403805 8943284 15451019 11528470 9278421 16887934 9295307
EGR1 FLT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10669633 10828020
CD40 CD86 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11207245 11581322 11698286 11964292 14764699 15034038 15197224 17200410 17317815 17371980 17513775 23002440 23125331 7523569 8760829 9359474
NFKB1 CD86 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10586028 15949284 19164127 15895390 18929846
EGR1 EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22198386 22593802 19913601 10395376 18844239 22433566 20472833 24470481
AR EGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18511414 8580999 7522959 15590903 14662770 18692155 17374439 18212060 20610535
EGF ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15748904 23331499 12093292 11279155
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
SP1 MPO â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12057865 17521322 8662930
SP1 CCNA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15922873 10196209
SP1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10720440 21447702 7497000 15345673 17170218 7491107 17049831 17014845 10982795 17486080
SP1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8864062 16928829 16704988 23662037 10773882 9353275 15661808 17984071 18430409 22347450 20739403 8994183
SP1 RARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16740727 7585542 15831516 9626663
SP1 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11160217 9339900 19753117
SP1 EGR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20427719 18044710 9282327 8349585 10826704 10082539 12637574
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
SP1 EPOR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21029371 7659529 23577103 8521844
SP1 GC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24382322 17312152 23137637 9493965 9632663 19244234 12052832
SP1 IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8940191 8184747 11026572 14593001 12217897 8910531 7896792
SP1 ODC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10374837 12297499 8132514 11149424 9115370 10448078 7876196
SP1 HSPA4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7553870 9060426 2674689 24669866
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
SP1 SLC10A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8405433 9620554 17192405 11336542 7632694
SP1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18801742 12760745 8007947 1588949 17384411 21465530 15618023 7896792
SP1 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10649433 16298343 11804592 11013220 20121949 7592908 21872590
SP1 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12200149 11517158 15247904
SP1 ABCC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17272513 22105759 24069312 16132117 11846400 10772892
SP1 MYCN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14567977 22815527 21123453 14645238
SP1 MET â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11910354 12473536 9223667 15067326 21831840 17283128
SP1 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 11013220 10454538 9670020 11283613 11074002 11283614
EGR1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18044710 17631285 7823937 12734378 22455954 15569263 8709978 16601242 12637574 10202038
EGR1 GDNF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19721135 9729303 21354245
REL IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8413223 20975042 23195252 19690169 19122653 8910763 14670622 17082635
NFKB1 IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 8413223 17707233 11058167 12686724 16433741 18285351 8021507 9878621 14960579 10963848 9058643 15543947 20696864 8679226 11035101 15972680 20336759 18772363 10080875 17082635
CEBPB IL1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21917825 12072435 9372929 16867259 20702408 17283046 10464291 16569740 10801783 15812237 22260630 10841183 10838190 10383163 9376596 17386941 10956548 12759449 11278846 12468538 11035101 11801594 2112087 12355443 15383601 16439360 19806478 22074460 16399630
IGF1 IGF1R â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11237532 12181198 17145802 19631971
AR IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19318566 15033751 17202144 19250214 20610535
WT1 IGF1R â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8390684 7497000 16698800 15345673 11001824 9076342 12444079 10499530 11896622 7791758
IGF1 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 21798082 23331499 8452530 21071413 12067807 1852007 21645859 8408032 14604834 19258508 11287679 23675206 19029956 2877871
AR IGF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24914937 8580999 17363459 22739988
IGFBP3 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10823924 11600567 22578544 1383255
IGFBP4 IGF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9722589 7683646 16924115 15642270
SP3 IGFBP3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12200149 16456404 11517158 15247904
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16417524
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 ZYX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17572661
AKT1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26553800 24492612 27521372 26216216 25949795 21151116 21565170
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
HDAC4 MEF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 12709441 15743821 11279209 15964851 10523670 23752268 11792813 11504882 18332106 10737771
PRKACA NFKB1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
NFKB1 BIRC3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21725609 23178297 23572150 9294162 9733516
NFKB1 NOS2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 21725609 23178297 23572150 7500013 7508926 9486205
NFKB1 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15231833 15050749 19343319 17673602 17000776 11880364 10733571 9733516 18566231 12010810 15723831 10823821 11297551
NFKB1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14576180 15517885 20159994 12165860 16619263
NFKB1 CD40 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17513725 11313274 19164127 11027342 17031478 9733827
NFKB1 NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10085153 11438703 17720813 16318585 9754583 16283237 18057724 9685183 17081374 12595462 15350552 19766095 23646894 24360823 11036073 15170030 22949549
NFKB1 BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 15756023 9733516 12010810 18566231 16453001 20103608
PRKACA NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19531803 12947093 17959673 15642694 15197457
NFKB1 NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9486205 7500013 19383900 7508926
HMGA2 CCNA2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17324944 21566082 17005673 14645522
CD40 BIRC2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
CD40 BIRC3 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19426221 12374738 24298274 9718306
CEBPB CSF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26114754 7513199 21455770 12355443
CEBPB CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16120603 22722334 19407981 11162569
UBE2I SP3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 15494207 12419227 25114211 18617891 18374648 12356736 15247228 16781829
AR UBE2I â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
UBE2I AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10383460 8798622 19692572 12764129
PRKACA HDAC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22865920 20716686
AR PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12933667 10075669 9886819 15691881
PRKACA ETV5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11682477
PRKACA WT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9366517 11237525
PRKACA ATF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8384217 8663317 20068231 11018520 11335727 11909979 9016641 12414794
PRKACA TFAP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10037142
PRKACA ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18799465 9855018
PRKACA RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16769902 7476969 20215566
RB1 CCND2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
CCND2 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 10498883 9315635 17303408 16236519 11520855 15279786 16326706 9190208 7575488 9003781 10385618 9736735 7736585 19075565 18590585 20068082 9425340 8449399 18786381 17660363 19651622 11254678 8343202 10778858
DNMT1 H3C14 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
TFAP2A ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19906305 10645007 7846046 22577344 18177484 15870067 9850080 10698518 16108032 11485026 18218085 12942124
AR TMPRSS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20308527 21761340 24505269 20623637 23192983 20610535 19176386
RXRG RARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 21988832 25910212 25303530 23331499 20211142 15604093 21071413 10529278 21516116 25416956 31515488 16189514 32296183 16713569 18988627 29892012
H3C14 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
REL NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24360823 10079054 23646894 7537042
REL BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12414938 23271966 11880364
CCNA1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7575488 18590585 17303408 10022926 16189514 17660363 15279786
CCNE1 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 7575488 18590585 9315635 17303408 17660363 12006580 11420722 15279786
TFAP2A RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11835395 9632747 21850486 9776742
EPO EPOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17145710 8662939 9442088 15358619 9030560 9974393 9774108 18586265 23331499 2163696 10318834 21889455 17327410 16982323 29997244 9808045
SP3 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10649433 7592908
SP3 GC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11908639 17312152 9632663 9045653
ATF1 TGFB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11776974 10567368
PAX2 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9916932 16631587 9178767 8760285 19342968
WT1 NPHS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16631587 15579507 21980157 15504938 23768159