Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
CEP126 NPM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CRK SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
WT1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18708366 16087727
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
SP1 MAP2K1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17889508 16452190
PRKCZ NCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9388266 16189514
SP1 WT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12683994 18064385
KPCZ NPM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29491746 31980649
ESR1 NUCL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 21182205 20348541
DOT1L NPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 20431927
ESR1 NPM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20308691 19805454 21182205 33731348 20348541
MYC RRP1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 30415952
RRP1B NPM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 20926688
RPL10 RPS6 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
KPCZ NPM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23402259 29491746 31980649
NUCL NPM3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22362753 22863883 26344197
MPHOSPH10 UTP14A â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
ESR1 RRP1B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 21182205
ESR1 MEN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 16651450
NPM3 NPM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 33961781
MYC NUCL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30415952 17314511 29467282
NPM1 NPM3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NCL NPM1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MPHOSPH10 RPS6 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
NPM NPM2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 25416956 26871637 28514442
RRP1B NUCL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19710015 20926688 27049334
NPM2 NPM3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
NPM NUCL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22362753 8620867 21048921 10503877 22939629 16648475 20431927 28514442 16189514
RRP1B NPM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19710015 20926688 33961781
MYC MEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
WT1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15286719 17634147 20842112
MYC RPS6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC RPL10 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333 11085504
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
NPM3 WT1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
UTP14A PRKCZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
MPHOSPH10 UTP14A â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
NPM NPM3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 23402259 33961781 22362753 24981860 26344197 22939629 26496610 26186194 28514442
RPL10 RPS6 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
TCF7L2 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 12095419 19561604 19895682 15579438 26947016 16204248 12799378 12907606 17360646 9727977 21533051 20133699 15576399 19784072 24447505 12591729 20818421 18852287 11973610
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC NCL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10606642 24951594 12695333 14519204 25018006 11983916
TCF7L2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17306568 17666529 23343194 21285352 15576399 21151179 22761862 22290435 16039586 19619488 19623618 17143292
PRKCZ SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23148884 16943418 18258854 19464346 27320013 17049555 20953893
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368