Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 AHSG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 PARK7 â—¼   CLEAVAGE ✅ 2.0 0.8 intact 23831022 8433088
NOS3 ACTN4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
AP2M1 AP2A2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15749704 15911768
AP2M1 AP2A2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15749704 15911768
IRF3 BAX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7900384 20360684
BAX SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BAX GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0912742107 20080742
TRIM28 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942393
BAX AIFM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12232790
SHC1 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220991 8621719
CBL SRC â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5219404 17141222
FGR CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12435267 7721825
ESR1 CXCL12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18563714
ESR1 CXCL12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16912174
DDB1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SHC3 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
TLR4 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17126326 5219377
NUMB EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR AGER â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0600362103 16954185
EGFR ANKS1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR KRAS â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 23220880 22908275
VDAC1 GSN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17254575 5219552
GSN RELA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN NEDD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GSN NCF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
NOS3 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SRC HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16844778 0604705103
HSP90AA1 FASN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSP90AA1 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
HSP90AA1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYH10 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
FASN IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MSH2 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRIM28 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
XPO1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SLC25A6 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10880512 5212735
KIF5B IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RACK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYH10 IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYH10 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ROCK1 MYH10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15774750
SRSF1 NPM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218180 16376875
NPM1 SUMO2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6541703 18259216
NPM1 CAMSAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HABP4 NPM1 â—¼   COLOCALIZATION 2.0 0.8 intact 7041060 19523114
SNCA PARK7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0020362 15502874
PPP2R1A PARK7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
PPP2R1B PARK7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
RELA PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0701877104 17606919
SUMO2 PIAS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PIAS4 CALR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSEN1 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21163940 114280
SP1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10446206
PSEN1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19012753 18996842
LCK PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
PPP2CB PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PPP2R1A PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PTPN11 SRC â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
PTPN11 KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26617336
PTPN11 JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 8766559
STUB1 RCN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RCN2 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RCN2 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 RUVBL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90B1 SLC25A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 SLC25A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18706393
YWHAH STK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8329523 22575644
TRAF2 STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STUB1 ACTR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB6 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HADHA TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF6 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19713527
PRKCZ ATP1A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12671055
SP1 IRF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22307793 22464952
YWHAB KIF5B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RACK1 SLC25A6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CYCS SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VDAC2 CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9615439 16713569
UCHL1 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
UBB SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
SP1 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19164283
PRKACA EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12840026
SRC SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10964917 8755247
INS SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8702728 10218944
SHC1 GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10704825 5212298
SHC1 INSR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805769 9593725
IL2RG SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 8643566
FGR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10329689 23109003
SRC HGF â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17574028 20802513
PIK3R2 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
LCK SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11078745 12096713
CTTN ACTR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12176742
RIPK1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18949366 24323043
RIPK1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21119000 18362886
NAP1L1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
ESR1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10935492 12878732
ELK1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19554388 18240315
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
PRKCZ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 10620507
RAF1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 30761125 27554335
STIP1 PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
COX4I1 UBE2O â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CHUK IKBKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 12799363 23430059
CHUK IKBKB â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 12799363 23430059
RELA KITLG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19197368 14563684
RELA AGER â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18622638 19616578
PRKCZ RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 12881425 5216561
RELA IKBKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 12842894 5216511
RELA NCF1 â—¼   COLOCALIZATION 2.0 0.8 intact 12618429 5216185
IL2RA IL2RG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RG IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RG PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10421845
IL2RA IL2RB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
IL2RB IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
SP1 IL2RB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9199305
IL2RA IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0607058103 17032757
JAK3 IL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
LARP1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PARD3 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PIK3R2 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
UCHL1 NEDD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NEDD8 PPP2R2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NEDD8 UCHL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SRC ASAP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC SP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SRC KRT10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7216098 17868192
PDPK1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PDPK1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29312296 16207722
PDPK1 YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12177059
KITLG GAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16873377 18697750
SP1 KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887648 19994725
SP1 VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11133225 7499419
SP1 SND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23160072 17350600
SP1 AGER â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10829018 9812979
SP1 PEBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24386147 9105667
PRKACA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRKCZ AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18650932 7232391
PPA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18948619
AKT1 LARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28650797
PDIA3 KITLG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TIAM1 PARD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17053785 5219245
PRKCZ VHL â—¼   COLOCALIZATION 2.0 0.8 intact 5219754 17350623
SNRNP70 AIFM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ELK1 SOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10191264
IKBKB MARK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219779 17363905
PRDX4 PDIA3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
GRB14 INSR â—¼   PROXIMITY 2.0 0.8 intact 5218466 16582879
UBE2O GNB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GNB2 UBE2O â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R2C PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STK24 PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R2A PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
STK24 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PRKAR1A PRKACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24855271 1252328
P4HB PRDX4 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 2.0 0.8 intact 8090267 21057456
SNCA GSK3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21985244 8209944
ESR1 NOS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17921256 0704315104
ESR1 CHAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
ESR1 HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16511840 23038705
YWHAH SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FEZ2 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
IL2RA JAK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15178252 16477002
FEZ1 P4HB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SDC2 SDC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
SDC3 SDC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18093920 0708909105
MAPK7 RPS6KA2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
NPM1 PA2G4 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RAF1 STUB1 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
COX4I1 VDAC2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
PIAS4 VHL â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 24002598 20844582 20300531
TRAF6 GSK3B â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31594754 30711629 31754475 30806153
SF3B1 SRSF1 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
MARK3 YWHAH â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
VCAM1 ACTN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 AP2M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CBL YWHAB â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
TRAF6 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 25499913
WDR26 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29911972 17041588
SHC1 DDB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 19380743
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
NUMB EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16273093 25754235
MSH2 RAF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27173435 31980649
VCAM1 MYH10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ESR1 RCN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
IRF3 GLMN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT2 UBB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
INSR SHC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 9121430 10482988 8702728 7559507 12237775 9446569 11075717 9710204 10803466 10896916 9741627 10921922 9593725 10816433 9083103 15629149 7499194 10764799
SHC1 SHC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SHC1 ACLY â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 19380743
CALU CALR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26344197
ROCK2 ROCK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AKT1 UCHL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25640309 16027165
ESR1 CAND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
VDAC1 AIFM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 29128334
ESR1 ASPH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 MARK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
PARD3 MARK2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 22883624
VCAM1 ANXA2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
AKT2 UBE2O â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 STIP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 VDAC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 XPO1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 SND1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
ASAP3 ASAP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
VCAM1 VDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
HSP90AA1 SRC â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ESR1 STUB1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HSP90AA1 STK11 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
UBE2O WDR26 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
CALR GANAB â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
SHC1 ABL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8112292 19380743 10194451
CBL FGR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 7721825 12435267
DDB1 NEDD8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16503656 18274552 16964240 21145461 18247557
EGFR ANXA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25136068 26320552
HMGB1 HMGB2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12517784 33961781 26344197 24981860
TRAF6 UCHL1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23717208 17353931 32814053
SHC1 IL2RG â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 8643566
RAF1 LCK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 8939988
TRAF2 GSK3B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 20562859 33961781
RAF1 CALU â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31980649 26496610 25852190
NR1H4 ESR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17333335 25675114
FGR HCLS1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 10066823
VDAC1 VDAC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31536960 22939629 29128334
SNCA YWHAH â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
SF3B1 SNRNP70 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
HMGB1 PDIA3 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
PSEN1 TRAF6 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
GAB2 SHC1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
IKBKB SRC â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ESR1 MTA1 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CAP1 CFL1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
SRC CBL â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 6538879 18273061
SRC CBL â—¼   PHOSPHORYLATION ✅ 0.84 0.84 mint 5219404 17141222
EGFR CD44 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11606076 16565089 12093135 15597342 23265944
AKT1 MSH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 24412244 28205554
PARK7 MTA1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20127688 21368136
AKT1 STK11 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28628118 24412244 28205554
TRIP6 SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 16713569 14688263
PDPK1 ROCK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
PKN2 AKT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10926925
ESR1 PA2G4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 SND1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
VCAM1 ZYX â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22623428 19738201
PIAS4 SUMO2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
LLGL2 PRKCZ â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
UBB UCHL1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
NEDD8 UBB â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
ACTN4 ESR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21078666 19805454 25604459
SHC2 EGFR â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8610109 16273093 24430869 22973453
EGFR AP2A2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 24797263 8548289 24189400 23956138 31959764
SRC ESR1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 17284441 6169640
SDC2 PDPK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 32707033 33961781
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
PPP2R1B PPP2R2B â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
NEDD8 VHL â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CHUK RELA â—¼   PHOSPHORYLATION ✅ + 0.85 0.85 Signor 10521409
MARK2 YWHAH â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
EGFR STIP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20029029 31980649
TRAF6 RCN2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 14743216
TRAF6 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10635328 16189514 22447928 29545793
IL2RA IL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17032757 16477002 1993646
ASAP2 SRC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10022920 17474147
VHL PDCD5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 24469044
AKT1 NOS3 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24379783
CYCS CASP9 â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 9390557
CARD11 IKBKG â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
ESR1 PTGES3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
AKT1 PRKCZ â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
INSR PTPN11 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
BAX VDAC1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
IKBKG RELA â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 15489227
PSMA6 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
NCF1 PRKCZ â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
EGFR RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
EGFR ITK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
PARK7 DAXX â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15983381 32814053
PIAS4 SUMO2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19471022 15383276 16713569 19394292 16524884 32786267 20016603 20696768 21252943 22578841 21693764
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
VHL NEDD8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16503656 17353931 15060148 18323857 11024059
ESR1 SP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10681512 17656465 17312152 16651265 18765668 10446910 15084343 16439465 15637147 19652226 15705965 15987735 9611253 15557281 9328340
MARK2 MARK3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32707033 19615732
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AKT1 CHUK â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
IKBKB KEAP1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NAP1L1 NAP1L4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RELA SP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PIK3R2 PIK3R3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
NPM1 NPM3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PRDX4 TXNDC5 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
IKBKB TRAF2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CHUK RELA â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
LCK CD44 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9573028 16189514 8576267
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
RAF1 KEAP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31980649 28628118 28205554
TRAF2 TRAF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32296183 16189514 16260598 21782231 16713569 25416956 9500555 33961781 21516116 21903422
SHC1 SRC â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
IL2RG IL2RB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11886175 10903799 8006584 20816854
PPP2R2A PPP2R2D â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
ACLY GSK3B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 10653665 30711629
CHUK TRAF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
AKT1 NOS3 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
IKBKB RELA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PPP2R1B PPP2R2D â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAB YWHAH â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EGFR PIK3R2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PEBP1 RAF1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CBL LCK â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CBL SHC1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CBL PIK3R2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
RAF1 YWHAH â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
EGFR ACTN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649 26320552
EGFR AP2M1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 20029029 31980649 24189400 23956138 24067654 25754235 31959764
AP2M1 AP2A2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 33961781 26186194 19380743 26344197
AP2M1 NUMB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24189400 23211419 33961781 26186194
VDAC1 BAX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 9843949 16189514 15637055 28760928 12767928
CD44 SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21701559 11084024 9519902
UCHL1 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20029029 32494592 31980649 32042339
SHC3 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22973453 9685397 8610109 16273093 8662772 9507002
EGFR FGR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
EGFR AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
GAB2 SHC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12135708 14982882 10704825 11782427
SHC1 IL2RB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 8294403 10602027
SUMO2 DAXX â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17081986 19471022 19394292 32786267 16475184 28851805 21252943 22578841 21693764 21383010
INS INSR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 2550426 11278498 29512653 23302862
INSR SHC1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
DAXX SUMO2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
MRPL12 MRPL53 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CALR P4HB â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
SNRNP70 SRSF1 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MARK3 YWHAB â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
SRC ABL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11494128 17474147 12522270 11781820 17318191
ABL1 EGFR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 16273093 25402006 7678409
ABL1 CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15556646 11494134 16713569 9174058 20675402 9195915 14604282 10829062 14725908 8626543 12475393 19380743 19823681 16955467
FGR ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16787943 11847100 16076903
AKT3 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14766748 15642728 17525161
CBL PPP2CB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
EGFR CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27059931 7657591 8665853 27903975 15107835 24797263 28791635 9756944 23799367 23175185 28198003 12734385 14505571 20940296 19155296 10635327 15117950 22833562 29629558 12061819 8662998 10086340 33762435 11994282 20877636 32714745 25005938 31182136 19578043 7782294 24714105 10799548 23158001 26055326 33617900 23153581 15210722 25872741 15657067 19947936 10428778 18508924 16969069 17971399 15962011 19531499 25521828 23774213 22976291 31959764 22591401 18255265 15735736 16713569 20562913 17880946 16914641 9890970 22394513 16729043 32114396 17995934 17182860 18319245 18271526 17545148 15383614 25140053 32377695 15465819 33627783 8798643 25754235 15282549 26177020 22266821 16923119 17242169 30544639 12604776 11239464 9130710 19225046 11370743 21772844 16105874 18273061 7592693 23897813 17486068 16246327 23457600 32904620 12803489 31120930 15668240 22203672 23418353 20124286 28541302 33323455 10092522 14627991 15677445 15159412 20308550 16849543 12593795 19836242 9121472 19713535 18316398 11408594
SRC CBL â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 29899407 17094785 16713569 18273061 7782294 12941616 10829062 31120930 15135048 17141222 18996392 8635998 11994282 22203672 19861161 16636290
CBL PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 17635922 10514377
MMP9 CD44 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16631740 11872628 1707285
PRKACA CD44 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16785995
SRC EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 17284441 6169640
EGFR TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31980649 24658140 23972990 25402006 18271526
RELA EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17881446 23379415
EGFR GRB14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8647858 23331499
ESR1 GSN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
KRAS HSP90AA1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16024644 15118125 15284455
IKBKG IKBKB â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 8209688 506093200 16126728
IKBKG RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15489227
PIAS4 IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15251447
ELK1 PSEN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12928043 12750007
HGF PTPN11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17881575 10871282 11323411
ESR1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21689749 22226967 18414489
SP1 STK11 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22412893 23995788
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
UBA1 UBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17597759 24816145 21209336
KIF5B GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ADD1 CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NAP1L1 CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SDHA CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
VDAC1 CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SUMO2 CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CSNK2B LCK â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
AP2A2 SHC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8617812 16189514 31980649 16713569 24189400 19380743
SHC1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
LCK GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11572860
LCK RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7935389 8939988 16189514
LCK JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278738 17570479 16189514
IKBKB CARD11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
CHUK CARD11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19909372 16301747 16356855
PPP2CB CARD11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21157432
RIPK1 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 24735611 23972990 16603398 8612133 32296183 16291755 11181075 19815541 24434549 30561431 21810480 11479302 31502302 27768232 20577214 25716317 21282461 25882049 8702708 9020361 16713569 29352166 23007157
PPP2CB TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17188031
AKT1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 25241761 28628118 10576742 19197339 19058874 28205554
PEBP1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17097642 14654844 16189514 11853019 15886202 21831839 10757792
SRC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17097642 16189514 7517401 8876196 10205168
PPP2R2A RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664191 23331499 16239230
AKT3 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19609947
IL2 IL2RB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11035066 16477002 8049354 8006584 22446627
PDIA3 CALR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 12052826 10436013 24981860 30021884 11823531 26344197
NCF1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12056906 27558335 19372727
CTTN YWHAB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 093880 8009870 20363754
YWHAB PRKCZ â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SRC ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24498420 14766010 15604093 11013076 27420286 29720121 12736255 18451880 15140878 23065768 17043237 17627277 7539106 11032808 17363140 20935677 14963108 11564893 12630920 22328528 15020686 15784253 17921256 24051437 10454579 17400812 17284441 16957778
SRC PPP2R1A â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
SRC PPP2CB â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15637081 15004239 15564375
SP1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10625617 19112177
ESR1 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20160136 20460377 22865929
SRC PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25814554 22402981
SRC KRAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30644389 26854235 9096340
PDPK1 PKN2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10764742 11781095 10753910
PDPK1 AKT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9368760 11825911 14500673 10698680 31467278 12149249 27563096 11313365 11278835 22569334 26264872 10226025 32876514 26256536 21775285 11438723 11445557 23397142
PDPK1 AKT2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 9228007 9094314 15890450
SP1 ASPH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17681019
SP1 ACLY â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11989980 10618488 10801800
SP1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7541039
AKT1 GSK3B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19713527 8524413 23824745 16009706 29464284 20856200 19995607 16123141 20682768 27563096 14645548 15688030 22337773 11035810 17428466 18505846 15470047 14701753 16282323
PRKCZ NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24379783
PRKCZ AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18353613 9512493
PRKCZ MAPK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20538799 11158308
GSK3B GRB14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24535599 28130417
INS P4HB â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25091901 31184304 21308844
GSK3B GNB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP2R1A PPP2CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15936019 16039140
PPP2CB SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21562258
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
GSK3B CAMSAP3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B SNRNP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17570479 17353931
MTA1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16807247 31527615 12167865 12639951 11146623 18451880
PRKAB1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11729179
AKT3 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24379783
AKT2 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24379783
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PTGES3 STIP1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GAB2 PTPN11 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
ABL1 CBL â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
YWHAH MARK2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 19553522 8009002 0803887
PPP2CB PPP2R2B â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
YWHAH RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 8005785 11697890
JAK3 IL2RG â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 7973658 16189514 27742835 7973659
PARD3 TIAM1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 17053785 15723052 23263278
PPP2R1A PPP2CB â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217765 15936019
EGFR SHC3 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
IKBKG RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
ESR1 SRC â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
UBA1 UBB â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
STIP1 HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ - 0.92 0.92 Signor 27353360
CALR CALU â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CBL SRC â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
AKT1 PDPK1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
SHC1 AP2M1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 31980649 19380743 24189400
IL2RB IL2RG â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PARD6B PRKCZ â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HSP90AA1 RAF1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
PPP2R1A PPP2R2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
IKBKG TRAF6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
CBL LCK â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 7721825 8621719 8900205 8626543 9178909 16107303 11741956 11904433
YWHAB RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 19595761 8009093
IL2RG IL2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16477002 8049354 11418623 8006584 10662798 22446627
PPP2R2A PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17245430 5219546
PDPK1 PKN2 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
LLGL2 PARD6B â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
PPP2CB PPP2R2D â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
EGFR CBL â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16729043 5218694
SHC1 CBL â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10570290 10025673 16713569 8621719 9541596 8662998 9461587 9434624 9234717 8950973 19380743 15677445
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
PPP2CB PPP2R1B â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PPP2R1B PPP2R2A â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PRKACA PRKAR1A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
SHC1 EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7518560 8034616 31980649 23956138 9544989 8610109 7542744 25402006 16729043 8665853 15657067 9742218 24797263 10049786 12577067 9756944 23799367 25187647 20935677 10766863 18271526 11408594 7506413 10635327 10595738 24189400 19531499 7542991 20473329 24430869 8662998 9020193 8887653 16273093 25754235 9388490 31959764 26551075 16713569 22973453 24658140 11196191 28065597 20067773 8810340 21278788 30544639 9130710 11370743
SRC EGFR â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31980649 8845374 21573184 25402006 7506422 10075741 19704002 10971656 23175185 10777553 22227249 20935677 20624308 21268077 17158602 24189400 9020193 16713569 22973453 11983694 24658140 28065597 21278788 17284441 7797556 20333651 7527393 10358079
SRC SHC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10482988 16189514 7499252 9096689 9710204 18840094 8939605 9388490 26551075
PARD3 PARD6B â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
KRAS RAF1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
INS INSR â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
COX4I1 UQCRC2 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
GRB14 INSR â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
SHC1 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
IKBKG IKBKB â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5219009 16938294
IKBKB IKBKG â—¼   PHOSPHORYLATION ✅ 0.98 0.98 mint 8209688 16126728 506093200
HSP90AA1 PTGES3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
HSP90AA1 STIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
GRB14 INSR â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 16582879 16934761 19648926 24535599 11726652
PPP2R1A PPP2R1B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
AP2A2 AP2M1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1B STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EGFR SHC1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2R1B PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CB PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IKBKB IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CB PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 CBL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
SRC ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 19901323 10964922 16497976 20841568 16787943 17570479 17318191 11847100 10500097 12522270 18691976 11494128 11781820 16076903 20168609 12748290 16464493 12445832 19369195 17474147
LCK ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16076903 16787943 17570479 11847100
ABL1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22553782 24974292 29066624 15657060 20841568 28177918
ABL1 HCLS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18305217 20841568
ABL1 RACK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 27170279 21124943 20841568 21978545 19423701
ABL1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9525940 11494134 16713569 20841568 10829062 17389395 16955467 12604776 9890970 10391678 9195915 14725908 7925293 11997497 12522270 15556646 9102067 11239464 11994282 9174058 12475393 20675402 19380743 14604282 8626543 15212693 19823681
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8617726 1623525 10194451 19380743 10592173 20841568 8112292
ABL1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20861316 17306540 20841568
ABL1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20841568 20101225 30692633
ABL1 TRIP10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19631450 20841568
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
BAX TRAF2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
BAX TRAF2 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
PRKCZ BAX â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10873802 10934475 10954424 14766748 15642728 17525161 20505164
BAX TRAF2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 20709625 21641962 22039431 23064052 23377657 23430059 23850759 26587781 7644501 8358790
SP1 BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11278953 10510469 11748232
RELA BAX â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18034190 18158998 20056115
AKT1 BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26763134 14766748 15642728 17525161
PRKCZ BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16679323 14766748 15642728 17525161
GSK3B BAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 29379583 27762303 15525785 20976235 26287183 17911107 16709574
BAX VDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 16189514 10365962 9843949 12767928
BAX CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9461218 10629050 20709625 9843949 11326099 12232790
CASP9 CYCS â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9390557 25313070 20462491 27697150
PRKCZ CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16287866
AKT1 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 11756412 11923280 16697215 20398329 18372248 15004527 15808505 20138985 20214616 15703181 17570479 28177918 18840507 15169778 11714830 10949026 16341064 11715018 18636226 10529400 9812896 17680028 19440551 10722653 20832730 18570873 17052453
PRKACA CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 29352269 15703181
AKT2 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9812896 15004527
AKT3 CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9812896
CYCS CASP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19788417 16977332 9390557 16713569 12147322 12773388 10329646 12792650 15210107
HSP90AA1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
KITLG CBL â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11994499 16780420 12444928 17904548
SRC CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 9525940 7782294 16713569 18273061 10829062 10799548 10934191 12604776 9890970 17570479 9013636 15135048 17094785 25784557 8635998 10092522 12522270 8621719 17141222 16636290 11239464 19861161 11994282 12941616 14739300 22203672 8849724 15212693
INSR CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 11997497 10635327 11994282 12522270 9525940 12604776 10592173 17570479 9102067 15951569 10829062 15212693 11239464
LCK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 9525940 10829062 10799548 10934191 7721825 16107303 12604776 9890970 17570479 11904433 9178909 10092522 11997497 12522270 8621719 9102067 11239464 11994282 11741956
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 9092574 19190244 11406619 11133830 7629144 17635922 11526404 8662998 8995358 8080844 15107835 23109003 17722974 8621719 16107703 9414268 10514377 15790353 19531499 22315502 19380743 25814554 9461587
SP1 CD44 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11316768 15111490 21193408 12972613 16943418 18372343 18596044 10976926 12091390 12943729
HGF CXCL12 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12649206 15059978 16212809 17145802 18633355 19631971 22763439 23402812 23667593 26366398 26819959 27474009 28475121 9242465
SP1 CXCL12 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15808852 23246486 21465475 19745163 23098564
DDB1 CAND1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 19748355 12504025 18805092 15688063 18851830 23453757 15537541 23535663 11961546 21463634 12504026 12609982 23535662 21863050
EGFR SHC1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
SP1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 1282800 17616668 18575762 19538880 15665278 18202149 20435036 21705183 18007664 21464950 23821666 15533438 9819401 10830317 8393457 16087726 20407012 18391986
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
RIPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11116146
FGR EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 31980649 24658140 11160627 25402006
EGFR SHC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 24212772 9507002 16273093 11791173 8760305 8662772
EGFR PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17496910 31980649 23956138 19531499 16273093 24658140 11172806 1334406 25402006
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 1382070 31980649 24658140 12560083 9230083 15212693 10377409 15647376
EGFR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 78.0 1.0 Omnipath 9544989 8808684 10595738 23956138 9388490 11350724 16273093 7542991 7681824 7518560 9710588 23799367 16713569 25402006 11370743 24797263 9742218 20935677 8887653 8034616 23331499 8662998 7542744 10049786 28065597 9130710 10635327 24189400 7506413 18271526 15657067 24658140 8810340 12577067 11196191 10766863 23178716 31980649 35384245 11408594 19531499 9756944 26551075 1623525 15951569 16729043 17956904
EGFR PIK3R3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17496910 31980649 25241761 16273093 24658140 25402006
EGFR SHC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 11350724 16273093 8760305
SRC GSN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10210201 23791551
HMGB1 TRAF6 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 18070982 15247281 21220427 12140561 12138165 8837778 19592497 18347055
HMGB1 TLR4 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 10952726 11672593 12646658 12803886 15802534 16267105 16327802 19931333 21372296 22842346 26618107 27048821 27192565
HMGB1 AGER â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20192808 9812979 19727205 25014009 32296583
HMGB1 TLR4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20547845 23519706 16267105 20348922
SUMO2 HNRNPK â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15161980 24782567 25114211 22825850 25218447 23092970
SRC HNRNPK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 7516469 17178840 24642125 12052863 7592945 16854432 16713569 21184736
HSP90AA1 SHC1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 16187797 15284455 17646646 16969069 17372273 17712310
STIP1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 10642522 21235734 21360678 26804907 11413142 24949977 19875381 10786835 20704274 21170051 26496610 27353360 25036637 19996313 9452498 18285346 24462205 22315411 20159553 22729780 22504172 11877417
PTGES3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16565516 10642522 11447118 26804907 15916966 11413142 16403413 21988832 11812147 19875381 19740745 14761955 12077419 10811660 20039095 22806877 25036637 20048054 19996313 18285346 20661446 22315411 23022381 18172314 20159553 22729780 22504172 16289154 9817749 14987994 8114727
HSP90AA1 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10744744 17145710 12441346 14743216
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
HSP90AA1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 25036637 19011619 16093354 8962087 18266962 8408024 23118896 22939624 24462205 16189514 17699868 20039095 16504566 20159553 17409432 16330544 15618521
HSP90AA1 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 1310678 16844778 16189514 18266962
HSP90AA1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12124224 11988487 11425855 11744239 9580552 12676772
TRAF6 IKBKG â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18180283 18347055 21220427 16547522
TLR4 IKBKG â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15064760 15814722 16115877 16603398 16547522
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
RELA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
TRAF2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
RIPK1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
IL2 IKBKG â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10807786 11280761 11460167 14660645 15289500 15563472 17301840 1825141 18264787 18758473 19528259 21133840 21232017 22224781 23650441 24699077 24958845 26755705 2965306 6164929 9625766
CARD11 IKBKG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
IKBKG RELA â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
TRAF2 IKBKG â—¼   DOWN_REGULATES ✅ - 84.0 1.0 ACSN 10542212 10754326 10820262 10925299 10952726 11112697 11274345 11280761 11438547 11460167 11875494 12133805 12433365 12646658 12811837 12907458 1431106 14607933 14625680 14660645 15099563 15199157 15465827 15485931 15536066 15592525 15644117 15699106 15749903 16243976 16413922 16713974 16818229 16878026 16970925 17237376 17254973 17301840 17363905 17404308 17462996 17485448 17693255 17916596 18264787 18345002 18633355 18641653 18716620 19392652 19411070 20038811 20138012 20184663 20300203 20435894 21133840 21217011 21232017 21411734 21807870 21826665 22435554 22955274 23086447 23170255 23390297 23422957 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 2649237 28462531 7594497 8910423 9743347
PIAS4 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19917246 20932475 20301198
TRAF6 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17562858 17728323 17947236 14695475 18180283 15620648 15125833 12867425 11057907
AKT1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20837477 20098747 17660512
RIPK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10880512 21383699 21458669 14653779 10980203 17702576 9927690 16603398 16547522 16965765 10755617
IKBKG IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 150.0 1.0 Omnipath 17145710 16938294 20932476 35339487 18266324 16260493 27929056 25979343 19666608 26496610 12133833 12192055 9751060 21423167 19706536 15836773 17561400 22099304 23986494 19959994 15327770 25400026 24266532 18450452 12657630 20434986 11583588 20200955 20300203 21903422 22990857 14743216 20167598 20098747 16126728 19656241 25852190 16906147 10195894 17000764 18329793 16186825 16547522 16611882 18037881 10968790 16497931 25286246 18462684 18207244 16603398 17965022 17977820 24240172 17568778 15084594 16129692 23506214 16319058 23123196 18949366 15218526 22605335 20368414 10837071 19820708 10980203 23131831 17363973 15214841 25304104 16493424 15184390 15691841 11864612 15802604 17693255 21455180 11865184 20211142 11971985 16970925 24469399 24618592 12486103 11057907 24369075 19365808 18583959 27426725 12612076 19422324 10094049 23109003 21803029 12459277 21640763 16285893 18266467 12709429 15620648 17072322 19815509 15749833
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
KEAP1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 27387502 20600852 19818716 25926686 24127568 24322982
PRKCZ MYH10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16611744 25869664 30655296
GSK3B PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 11104755 17389597 17360711 16814287 10997338
PRKCZ PSEN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 14576165
PTPN11 GAB2 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 10358138 10849428 10982827 11447289 11572860 12138178 12640133 12707331 15240681 15699106 15713798 16212621 19833085 19909365 9751747
PTPN11 GAB2 â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 10358138 10849428 10982827 11447289 11572860 12138178 12640133 12707331 15240681 15699106 15713798 16212621 19833085 19909365 9751747
PTPN11 IL2 â—¼   DOWN_REGULATES ✅ - 26.0 1.0 ACSN 10358138 11447289 11449354 11572860 12138178 1238444 12393695 12421919 12707331 15169881 15240681 15699106 15713798 16204085 17307799 19406987 19479342 19833085 20363967 20435894 21469115 22483603 22683124 22955274 27557510 9751747
LCK PTPN11 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 12947224 15358536 18173375 18759926
INSR PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8135823 9832615 7493946 9593725
PTPN11 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 11287610 15356145 12135708 10391903 19172738 23331499 14982882 11334882 11027663 21636860 10973965 19909739 11812650 10068651 11572860 15170389 9885561 15010462 18950707 16253990 18725415 10871282 11782427
PTPN11 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 18950707 23109003 16371368 17722974 22315502 16107703 9660791 8080844 9632795 15790353
PTPN11 SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18757826 18482983 10698938 17974954 14687660 24632723 20308328
STK11 PRKAB1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 14511394 15579580 8779952 14985505 14614828 11018120
PRKACA STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11853558 17482548 11297520 17482549 10642527
PRKCZ STK11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11853558 18250273 19414597 16407220 18321849
STK11 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12973359 25069613 20592207
STK11 MARK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19369195 12879020 17192257 14976552
STK11 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19197243 15509864 8910387 20160076
STK11 MARK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 14976552 19369195 28711359 22238344 17573348 17192257
PTGES3 STUB1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
PTGES3 STUB1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10197982 10995457 11283614 17055429 17327415 18566586 19387550 19662498 20027199 20093776 20713526 20959453 2191300 21945180 22032831 22869732 23430059 23551398 25103413 25487024
TRAF6 CARD11 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11274345 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15836773
TRAF6 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16260493 15691841 15620648 15327770 10195894 16186825 16493424 17965022 10094049 10837071
TLR4 IRF3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 14517278 15210742 14703513 9566918 17823124 17157040
IKBKB IRF3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25070846 20604809 9566918 14703513 19153595 27992402 18272581 16914100
SRC RACK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 21685945 12400005 23652203 22174419 16849317 9584165 11279199 17574549 16189514 21978545 21677780 22523568 18596232
GSK3B CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15288510 16288047
SP1 EZR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21628504 19164283
SRC EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16438931 22397367 14504278 25231728 21818323 24339867 15623525 18701134 22262457 24385580 18078820 28306714 15647376
ROCK2 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 8522586 20737283 9456324 9287351 10970850 12778124 12045227 12802084 7579708 10047517 8527459
ROCK1 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 8522586 9856983 14504278 15531580 9287351 10970850 12778124 12045227 11387207 19255442 15843435 12802084 7579708 19386264 10047517 8527459
AKT2 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 14504278 15531580 10970850 11387207 15843435
SHC1 GAB2 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10086337 10358164 10567412 10811803 10849428 10982827 11447289 11449354 11777939 12175651 12393695 12640133 15567848 15574420 16076871 16212621 16582911 16887996 17496910 17673906 19449109 19909365 26552706 8551221 9763606
IL2RB SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8294403 8700888 8643566 10602027 16189514 24737791
GAB2 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8995358 10704825
LCK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 9446569 17389395 18578522 10921922 10482988 10764799 18452278 20068231 18669648 12522270 9685404 10896916 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
SRC SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 19901323 9388490 8939605 9096689 10971656 16497976 15592455 9121430 10891441 17389395 11687594 10329689 10482988 20068231 17570479 16189514 9685404 23109003 7516469 9927207 18840094 15688026 15212693 1409579 14963047 9710204 26551075 17016520 11075717
INSR SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 93.0 1.0 Omnipath 9083103 17145710 19901323 10803466 20230923 16497976 9121430 15592455 9446569 17389395 18578522 7559507 7537849 10482988 10764799 10921922 18452278 20068231 10592173 7499194 18669648 15629149 12522270 9685404 10896916 9927207 9593725 12237775 8702728 8610109 19651622 15212693 9741627 9710204 19664994 7685165 8626723 17016520 10816433 11075717
SP1 HGF â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9223667 17967179 12482909
LCK ITK â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9500442 10571988 25386784 11145737 7539106 27748765
LCK ITK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 21747996 28516764 19132916 23109003 20305788 23982207 15771581 19690332 28644030 15144186 9312162 12842872 17192257 23946894
LCK IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10214954 2047859 10602027 18348982 16189514 12200137
LCK PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11526404 15032589 14583609 23109003 8397196 10488096
PDPK1 CARD11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15802604 21900206
TLR4 RIPK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16603398 15814722 16115877 21931591
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 DAXX â—¼   PHYSICAL_INTERACTION 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 DAXX â—¼   SHARES_COMPLEX 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 DAXX â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 14744430 15592525 15760909 16406523 16498403 16940415 17462996 18545270 18641653 19392652 19427028 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9184224 9488730 9759866
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
TRAF2 DAXX â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TRAF2 DAXX â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16406523 16498403 16940415 17462996 18641653 19392652 19524513 19597341 19632174 19838173 20452955 20531300 21133840 21232017 22427918 23010170 23069999 23377657 23850759 24378531 26587781 26653790 26972597 27984721 28574505 9488730 9759866
TRAF2 CHUK â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
TRAF2 IKBKB â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
RELA TRAF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15041463 19392652 21573233 15723831 9733516
TRAF2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15725726 12547194 11359906 25241761 20449947 9244310 16713569 23007157 10795740 24323043 19150425
TRAF2 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 27387502 15725726 12547194 11359906 25241761 20449947 16713569 18362886 23007157 10795740 21119000 19150425
AKT1 MMP9 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 17409395 17680028 18471976 19440036 19930715 19945467 20214616 20398329 20609352 21084277 22131018 23572150 23589069 24030100 25136802 26597054 27328425 27510662 27572739 29556339
SP1 MMP9 â—¼   UP_REGULATES ✅ + 21.0 1.0 ACSN 10048576 10964912 11007770 11013220 11114293 15001984 15592504 16079281 16556862 16716598 16831886 17490644 17705132 18353785 18832382 19564415 20589835 21252118 22439866 23338822 8844971
RELA MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 48.0 1.0 Omnipath 18298869 12105194 11376631 14600595 17673602 23423566 17922642 15605368 14755547 20332461 18357389 21502320 17186550 11060311 18566231 9679762 16554298 16687076 17121934 15086314 18843978 21963718 18056465 20103608 21238464 17174275 15536164 18028425 17158602 17590163 19303700 7860222 19539355 9500201 22587999 19783786 18567920 15175338 17498959 19616091 10359016 18801463 19454280 24755270 19662350 12193473 16014933
SP1 MMP9 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 8226872 24755270 18028425 9514098 9520415 23799155 20529870 21840940 7860222 17049831 21963718 18357389 9150367 11060311 19616522 11830485 9748266 20638438
MMP9 KITLG â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 15526160 12062105 9256427 17344430
RAF1 YWHAB â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
RAF1 MARK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
RAF1 YWHAB â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 10358164 11532940 12566895 14764585 15516985 16102570 19289794 19565474 24027568 7510700 8551221 9069260 9763606 9846483
KRAS RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 10958680 12750173 9516156 12932319 9665134 10783161 8805624 1386920 1639773 8340422 8601312 19595761 23331499 16041367 21071413 8332195 9446616 10882715 25852190 10531446 1996324 19029954 8503013 16093354 19541618 23153539 16293107 1708096 19933846 26721396 11136732 10205168 20802526 31980649 7760835 18775988 8307946 12917261 11134016 20080631 8180183 1990291
PRKACA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19007248 11971957 20166139 18767875 20230923 9001246 10576742 23331499 20068231 7935389 18669648 18691976 9922370 15664191 19651622 12801936 9091312 10862777 9710607 11997508
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
PEBP1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 23331499 10757792 23416466 10490027 17706925 21831839 16189514 14654844 15886202 11585904 17097642
YWHAH RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12801936 11697890 8702721 17979178
SRC RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 7692235 12551923 7517401 17097642 15258589 9689060 16189514 16630891 10998357 11376654 29063113 8876196 10205168 28846113 12952943 22592532 11134016 15710605 16170185
RAF1 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 8085158 12620389 16093354 19595761 7882972 16041367 24255178 11697890 7935795 8702721 10848612 16189514 25852190 7644510 12360521 10620507
TLR4 CHUK â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15064760 15814722 16115877 16603398 16547522
CHUK RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
AKT2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19609947 12048203 10485710
AKT1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 15710601 12048203 25241761 19442713 11278366 10485711 15800029 19609947 17570479 17660512 18515365 19088076 10485710
SRC CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 12707358
ERC1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15218148 16970925 16497931 15371334 15218526 17072322
PEBP1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11585904
CHUK RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17145710 15611276 22110409 19609947 10521409 20863851 20051109 20363318 12767944 26999213 12842894 21903422 19110719 15858576 16382138 22155370 23894194 16046471 15128824 21569639 16846590 8246997 15485852 25341660 15494311 11983155 15980040 15489227 15849198 14636585 23343355
CHUK IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 91.0 1.0 Omnipath 9346484 24911653 20932476 28514442 11971985 16970925 12210728 9346485 17965022 16713569 12486103 9891086 15456791 11057907 20434986 16129692 16260493 21903422 21724995 16286467 14743216 16319058 18949366 10779355 25748427 25852190 12244103 11585904 9751060 15218526 10094049 10837071 9914500 21575199 9721103 25241761 10195894 9689078 15214841 21784860 17561400 21640763 16285893 10733566 16186825 16493424 10022904 12709429 12351658 10968790 12547194 15691841 15620648 15327770 11864612 11460167 14636585 17693255 17072322 9346241
PRKACA RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 17462920 12628924 19197368 19122653 18385332
IKBKB RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RELA NOS2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14668329 15079071 15536066 17145890 17404308 17550372 19171876 20138012 23430059 8383323 8580069 9743347
RELA IL2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10679398 12133954 12759422 14668329 15079071 15536066 17145890 17404308 17550372 19171876 20138012 21224476 23430059 8383323 8580069 9743347
SP1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7636984 8450395 9151857 20538607 11964305
RELA IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 7623820 8814256 22427656 9417120 9605137 15477007 9111330 21832163 9135552 8383323 8934574 11035116 7730629 16275766 9737979 19968887 28199730 1604322 15585831 8977179 12027419 18045535 18207244 17179947 23578476 15710339 9233628 11145913
RELA AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20186924 18031796 20649564
RELA IL2RA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23144749 9135552 11781710 7636248 8430069
RELA NOS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 23085209 17720813 12057007 15350552 17068060 20600530 18596035 24360823 11036073 10085153 16318585 24014650 17035338 16169848 9754583 14978160 16283237 19766095 15170030 9712833 18057724 9685183 17081374 17041221
RELA VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10833420 20966071 16317091 7536741 16627481 16385502 10946302 19422386 22708120 23042817 19281832 10553096 10329958 11359843 7692229 16249517 10496926 7537851 16453001
RELA NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18397880 14570928 17081374
PRKCZ RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11684013 21515635 15210811 21131967 12881425 34230209 16189514 17183360 33864076 27466442
PPP1R13L RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12134007 10336463
GSK3B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18201972 15465828 15280197 22761446 20537194 21194439 19345186 21660967 19997086 16407239 25629551 17183360
IKBKB RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 135.0 1.0 Omnipath 15280197 17785205 27329558 22110409 22753932 22205033 21765477 15611068 18519641 15858576 25241761 33579825 23536830 28122346 19393267 34556881 24442433 14560022 15192014 21242976 16840782 19609947 33789981 10521409 26826124 21492457 19110719 23303310 16105840 22212641 26587973 34219129 15210811 16046471 11359840 27626700 15128824 28416608 17178723 21674813 17362989 28737909 19377466 15980040 16407239 15849198 20507904 26082493 15557193 34082140 21798539 26267322 29363544 12767944 20224721 26307684 12842894 17108032 26170389 24336331 27315556 31980577 11259436 34380537 20872791 21674474 15465828 15994321 17548605 26603838 16148147 25136068 33914760 26569329 22234699 17012367 14636585 22039465 32123095 15212693 27466442 33883226 15611276 22081069 19197368 17070014 20051109 26693062 14963024 33971703 28381553 33459422 27244888 18544167 18922932 20188669 15485852 20696864 22689577 17982102 20410276 15489227
PRKACA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 11931769 15833743 9150141 17959673 9660950 16135789 12628924
RELA SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12055073 7933095 10671503 20861353
IL2 IL2RG â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RB â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
IL2RG IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RG â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RG IL2RB â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10807786 10820393 10849428 12095053 12811837 14607946 15289500 15563472 16212621 16799562 16815076 17371980 17398124 17459805 1825141 18758473 19528259 19833085 19913445 20007590 20856220 21307131 21840487 22224781 23124025 23650441 24829413 25582338 26755705 2965306 6164929 7512720 7521688 7523571 8683106 9625766
IL2RB IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
IL2 IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 15265897 16477002 10807786 19528259 19833085 7521688 17371980 8049354 15563472 18758473 10662798 15289500 23331499 26755705 8683106 23180781 12095053 11418623 6164929 9625766 24829413 1825141 8006584 16799562 7829965 8568232 10820393 7512720 23650441 20856220 7681595 10849428 22224781 1631559 16212621 21840487 26192618 2965306 8260650 23124025
IL2RA IL2RG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15933202 15265897 8568232 8260650
IL2RG JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 23331499 7973658 7973659 18445337 10856136 16189514 10629052 15621723 7973657
IL2RG IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 8568232 15265897 7514277 10903799 11886175 8026467 15933202 7681595 15178252 1545122 8260650 16189514 11851401 8006584
IL2 IL2RB â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RB â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2RB IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 8568232 3095922 15265897 16477002 11035066 3098894 15933202 1940342 15178252 8260650 3116143 22446627 8006584 8049354
JAK3 IL2RB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 7693677 16189514 10825200 7973659 9553136 7973657
IL2RB IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8568232 15265897 11886175 15933202 15178252 1545122 8260650 3116143 8006584
TLR4 IKBKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15064760 15814722 16115877 16603398 16547522
CALR PDIA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
CALR PDIA3 â—¼   PROTEIN_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
AKT1 NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12734380 34264265 25761062 33139577 20920494 10559253 26774451
PRKCZ NCF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 8626435 12734380 96198102 11145703 12056906 94375440 8089108
IL2 IL2RA â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
IL2 IL2RA â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 10807786 10820393 10849428 12095053 15289500 15563472 16212621 16799562 17371980 1825141 18758473 19528259 19833085 20856220 21840487 22224781 23124025 23650441 24829413 26755705 2965306 6164929 7512720 7521688 8683106 9625766
NFATC3 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7739550 9017603 21642596 17513763 7730629 8543769
SP1 IL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10656874 12560487 9175624 9756940 8814256
IL2 IL2RA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 6815536 3095922 15265897 12649439 16477002 15933202 1940342 17032757 15178252 8260650 3116143 8894436 1993646 8580082 8960125
KRAS YWHAB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 12068308 23352452 25907612 15035987
PRKCZ YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16189514 10620507 21900206
IKBKB YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16024783
AKT1 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
PRKCZ SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 10527887 11447289 19615955 16488589 6321473 8321321 12845332 11313945 16189514 12040186 19568798 15567848 14585353
PRKACA SRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19651622 17081983 20166139 2474754 18088087 15546918 19664994 11804588
SRC PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21780115 15032589 11526404 23109003 22880054 10488096
SRC PDPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20643654 14585963 16314505 11481331 15212693 12738763 1148133 15302935
SRC TRIP6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16880273 21689746 15988003 14688263 23576104 17591779 27134758 16713569 20876301
SRC TIAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12810717 19285946
SRC ANXA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 30081903 15302870 24239898 23594883 18083107 2415974 26716413 17389395 27821486 11106497 88296872 16189514 25574848 25303710 2456953 24727000 17287340 2143014 15212693
SRC NOS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20015194 19875457 16116474
SRC CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 19802004
SRC CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 70.0 1.0 Omnipath 27603901 22823952 7680654 9748248 28522963 19419567 19690332 16497976 15592455 19413330 25077552 17389395 19534553 20068231 28769876 17570479 20708589 19273217 18491316 18669648 16162656 25682866 12522270 18088087 22761768 26142315 17287340 27009365 10921917 9683637 24465712 27758765 24675741 12601080 18707149 16212419 15169891 7519605 17016520 11389697
SRC IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 12645577 12707358 15456896
SRC ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 32.0 1.0 Omnipath 15784253 25364741 17400812 16957778 17627277 15140878 11032808 23065768 12736255 7539106 17921256 27472465 14963108 24487689 25275301 12630920 22865929 14766010 30148069 11013076 15020686 9500442 17284441
SRC SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15212693 12893833 11162638 11744621 28671665 24860424 11078745 12096713
SRC GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10391903 12464621 11640929 9885561
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
ROCK1 ADD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10209029 24668294
PDPK1 KRAS â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
PDPK1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 11687500 11747822 12670391 15802604 17680028 18802401 19109239 19122654
PDPK1 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12887331 14500673 11222751 18691976 10075713 20332120 9768361 9748166 17335005 10357815 16189514 11141077 16051884 11781095 10764742 14604996
PDPK1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 15743829 15191648 10679787 23331499 19203586 15718470 26491696 26937223 9374542 24169049 15890450 28589878 9512493 12048203 10822383 12434148 20059950 11134526
PDPK1 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9512493 12162751 10208883 23603119 19203586 15718470
PDPK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 156.0 1.0 Omnipath 15505410 12538620 12176337 19951971 24352480 11752451 19401591 11369519 10698680 10601311 15718470 24950409 20481595 24169049 10570282 16798838 14993273 11500365 9368760 19844585 17680028 7637810 9169478 26256536 7722458 9094314 12750173 11438723 18802401 9252186 23331499 18456494 9104825 10592173 16189514 20361045 18988627 11278835 20163786 20333297 20041157 12808134 19602588 8630736 10207050 11241670 10438924 9868760 25912234 20153221 25582703 11445557 21775285 12149249 14666721 18596232 9512493 23397142 11809791 12167717 21798082 16033886 10679787 16787925 29562639 15550174 21071413 8978681 10833263 19203586 10226025 26937223 14500673 20161206 11136732 11825911 11042193 9642236 22569334 18662999 9736715 12242303 11313365 11598012 11134526
PDPK1 PKN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16219676 10753910 10698939 10792047 11781095 10764742 18669648 15302935
PDPK1 RPS6KA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19369195 10480933 17192257 17906627
PDPK1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 16026785 20732331 15481030 22493239 10698939 9707564 8706898 20137943 21774789 17192257 22154087 20481595 12372837 16765046
AKT1 GAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 11782427
GAB2 PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9973481 10982827 18950707
SP1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12759366 19105596 15722551 18624763 12684688 9614091 10574932 10713142 15061658 12270858 15180995
SP1 INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 1311316 18310298 7776968 15131018 12706836 12665574 7983788 16707431 22033326
SP1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12759366 16574895 16790435 9458366 9415398 12169688 10949931 12694408 11562358
SP1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9348238 17446237 23626778 18664368 14744869 15001547 23027183 14998783 17449871 15330762 19485892
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SP1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19145069 15342781 21520171 18353772
SP1 SOD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8921911 18586551 18608091 21056687 24946209 11724400 9867871
SP1 BSG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22678117 20629990 21470566 20384626 24906624 11814679
PRKCZ SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23148884 16943418 18258854 19464346 27320013 17049555 20953893
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
PRKCZ AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11585925 15884057 14560023 16189514 11748077 18353613 11723139 10085094
INS AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 29432553 23912456 11679435 23866690 17335965 24646332 23798298
PPP2R2A AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 18039929 19216069 18077353 19556239 19996169 10026142 10995457 18042541 20452955 18559511 18588945 16680151 20360384 16406523
PPP2CB AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15367694 11087733 18039929 19216069 18077353 19556239 19996169 10026142 10995457 18042541 20452955 18559511 8650155 18588945 16680151 11812651 20360384 16406523
AKT1 NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 70.0 1.0 Omnipath 12759249 20166139 11756412 10376603 11923280 12446767 16697215 11044445 20398329 18372248 11696579 16126727 16839566 15808505 20138985 20299462 10908731 20363286 11988487 11425855 20214616 23103584 11729179 16043647 17570479 12171920 25460366 27322328 11978735 15169778 11029403 25241761 19654415 10949026 18048761 11715018 12791703 24379783 18636226 9812896 23397142 17680028 10376602 12431978 10722653 20832730 18570873 25009123 17052453
AKT1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 23331499 17680028 20214616 17688959 20398329 16537363 17052453 19575820
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
AKT1 S1PR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 11583630 17570479 25588843
AKT1 ZYX â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17572661
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15184909 25241761 22689577 15856005 10485711 17660512
AKT1 YWHAH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
PARD3 TIAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24152735 23109003 17353362 17053785 15723052
KRAS PRKCZ â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 10228164 15314172 11689445 28539435 11726503 19879889 8635462
PRKCZ ADD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 8810272 17081983 9679146 16116087 15212693 15611095
PRKCZ NR1H4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18668687
PRKCZ CHAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12486117 15381704
PRKCZ MARK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15084291 15324659
PRKCZ IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10195894 9689078 10779355 11460167 10022904 10356400
PRKCZ PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24152735 23109003 17353362 12390250
PRKCZ GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18353303 14657655 11481324
PRKCZ HABP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14699138
PRKCZ AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9512493 25241761 12162751 9305920
PRKCZ MARK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15084291 21983960 15174125 24719451 23312004
PRKCZ AQP9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21873454 17081983 17346701 28419510
PRKCZ PEBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20166139 10891480 20068231 12551925 14654844
PRKCZ ADD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 8810272 26639316 9679146 16116087 15212693 15611095
PRKCZ GRM5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15894802
PRKCZ PPP1R14A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15003508 12030846 11287002 32471307 15665049 12563012 15184667 12604330
PEBP1 IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11585904
PPP2CB IKBKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19607706 17188031
GRB14 INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 19648926 24535599 16582879 11726652
INS INSR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 8393875 21743783 21317886 24296476 26374090 29069585 26245346 16956584 19902173 20332342 23363978 23331499 18988627 23302862 22832498 2550426 15870194 11278498 19752148 29512653 23304064 24633815 17227660 22521887 23223021 30197476
ESR1 INS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20616010 20068169 16950141 21029304 19433249
INS AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20338882 25304263 30179516 23832510 23801578 22307032 20041157 24725432
KRAS MARK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15035987 21779496 24957944 22510884 23352452 25907612
PPP2CB AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 18039929 19216069 10026142 10995457 18042541 20452955 18559511 8650155 18588945 16680151 16406523
PPP2CB AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18039929 19216069 10026142 10995457 18042541 20452955 18559511 18588945 16680151 16406523 18160256
AKT3 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20016067 17680028 20214616 17688959 20398329 16537363 17052453 19575820
PRKAR1A PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17145710 15655353 17353931 26687711 11834733 24855271 32296183 24700472 9405392 25477193
PRKACA ACLY â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 19415658 17081983 10653665 17924679 18767875 18088087 18452278 18669648 15302935
PRKACA ADD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 17081983 9679146 8810272 18669648
PRKACA STK24 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10644707
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
PRKACA NOS3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 15319357 12522122 34204249 10376603 31923467 16839566 33429979 34026871 16946136 10908731 10671564 16270749 11729179 12171920 26132171 11978735 17572401 24379783 10376602 16873402
PRKACA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16543730 15845746 18691976 19836308 8524413 12054501 16039586 12147701 16522636 11035810 18669648
PRKACA SRSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22393468
PRKACA ADD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 9679146 8810272 19664994 18452278 16116087
AKT3 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 12851486 15023346 21303971 11882383 17680028 9065430 23109003 20214616 22094462 23552696 20398329 21506126 20028971 12040186 18218901
AKT2 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 17145710 21303971 11882383 17680028 9065430 20214616 22094462 23552696 12434148 20398329 21506126 26051358 16293724 20028971 12040186 9712142 18218901
GSK3B ACLY â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 17145710 20058876 10653665 17353931 2176822
GSK3B MARK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 16257959 18424437 28236972
GSK3B CAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30894654 30123351
GSK3B VDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 16288047 23993956 29682501 18381814 25296756 21530686 22995655 26883165 19720099
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
KRAS PEBP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17097642 10490027 25597358 10757792 19158341 18294816
MTA1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15226262 11146623 12527756 24413532
ESR1 NOS3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22052999 11029009 10690351 14742696 19914929
AKT2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11139588 11432835 11507039 9528769 7838153
MTA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11146623 18451880 12167865 16807247
MARK2 PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22883624 14653998
FGR SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11162638 11078745 11744621 12096713
FGR PIK3R2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21780115 15032589 11526404 23109003 22880054 10488096
FGR HCLS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 8578591 8611520 9104825 9183008 10066823 96108162
PIK3R2 KRAS â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 31135801 24897931 8665852 17998941 11136978 21779505 8052307 12121613 1716764 26085527 21779497 12094235
ROCK2 PPP1R14A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12144526 12495628 10869555 32471307 12563012 20506308