PKG

Protein list:

PRKCZ ELK1 HNRNPK NASP TRIP6 PPP2CB MMP9 NFATC3 CHUK RAB14 PSMA6 LARP1 PPP2R2C IKBKG PDC ITK HGF PPP2R1A ROCK2 GSN DAXX NOS2 YWHAH HLCS ARID3A RPS6KA2 IL2RG SHC1 BFAR SDC2 MTA1 ERC1 PPP2R2B PPP2R2A SDC3 PTPN11 PIK3R5 JAK3 INS ANXA2 HCLS1 STUB1 ASAP2 TRIP10 DDB1 CTTN KRAS GLMN ADRA1B CSDE1 FGR S1PR1 SNRNP70 KITLG PIK3R3 PPP2R1B IL2RB ROCK1 CARD11 SRSF1 LNPEP TDP2 SNCA PKN2 LCK INSR PIK3R2 IL2 ANKS1A SHC3 TLR4 GAB2 PPP2R2D SHC2 PRKAB1 VEGFC IL2RA CXCL12 VEGFD TIAM1 SPAG7 STIP1 ZYX PPP1R13L VCAM1 RUVBL2 UBB CBL SRXN1 TRIM28 ASAP3 SF3B1 IRF3 ADD1 BAX AQP9 MARK3 ATP1A1 MARK2 ADD2 MYH10 PPP1R14A CHAT RELA HABP4 STK11 NOS3 NR1H4 PSEN1 CASP9 YWHAB GRM5 NCF1 TRAF2 VHL SP1 AKT2 IKBKB AKT1 AKT3 PDPK1 GSK3B RPUSD4 SEC61B HIST1H1A MRPL12 SRC ESR1 EIF5A AHSG SHMT2 MTNR1A TECR MAP1LC3B MLKL PGD HSPA6 HADHA PPP2CA YWHAQ DAPK3 MAPK15 GANAB AGER CSNK2A3 DNAJA2 YWHAZ ECT2 HUWE1 SLC35G1 POLD1 PFKP WDR26 HSP90AA1 NIPSNAP2 PDIA3 CSNK2A1 GRB14 RAF1 KEAP1 APPL1 GDI2 ACLY HDAC6 PRKCQ FEZ1 HSPA8 CDK1 DIDO1 UBE2O CPT1A FKBP3 STT3A PARD3 XPO1 SDHA ADAP1 NOC2L SND1 COX4I1 TLR9 FKBP4 BLVRA P4HB PRDX6 ARHGDIA POLRMT AP2A2 PFN1 OLA1 GOT2 PARD6B GART ECHS1 PRKCSH UBA2 FBL CAP1 CYB5R3 MTHFD1 AHSA1 SUB1 TRIM41 PAICS VDAC2 ACTN4 PDCD5 NPM1 RPN2 VDAC1 FARP2 CDC42BPB PDIA6 GTF3C5 C1QBP PRDX4 SLC16A1 HPRT1 EGFR TXNDC5 PTGES3 NIPSNAP1 HSPB1 MARCKSL1 FASN HADHB CD44 NEDD8 DDOST EZR BASP1 CSE1L TUBB4B CSNK2B GNB2 TUFM UBA1 WWC1 AIFM1 CAND1 STK24

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Protein:

Eg: PBRM1 | ARID1A | BRCA1

Function:

Eg: Homologous recombination

Path:

Eg: SMC5 > DMC1 | PBRM1 > BRCA2

Relationship:

Full list of relationships

Graph tools:

Note this may take some time with > 30 proteins

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PKG Score Threshold: 0.8

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Source	Target	Relationship Type	Directed	Sign	DB Score	PKG Score	Database	References
ACLY	GSK3B	◼ PHYSICAL_INTERACTION			0.88	0.88	HIPPIE	10653665 30711629 17353931
ACTN4	ESR1	◼ PHYSICAL_INTERACTION			0.85	0.85	HIPPIE	25604459 19805454 21078666
ADD1	CSNK2B	◼ PHYSICAL_INTERACTION			3.0	0.9	intact	21900206 2001699 8089645
AHSA1	EGFR	◼ PHYSICAL_INTERACTION			0.82	0.82	HIPPIE	31980649 20029029
AHSA1	FKBP4	◼ PHYSICAL_INTERACTION			0.84	0.84	HIPPIE	25036637 22504172
AHSA1	HSP90AA1	◼ PHYSICAL_INTERACTION			969.0	0.96	STRING	36370105
AHSA1	HSP90AA1	◼ POST_TRANSLATIONAL_REGULATION	✅	+	16.0	1.0	Omnipath	25036637 16696853 17145710 19875381 12604615 24462205 26693507 26804907 22315411 12504007 20226818 20159553 22504172
AKT1	LARP1	◼ POST_TRANSLATIONAL_REGULATION	✅	-	2.0	0.8	Omnipath	28650797
AKT1	GSK3B	◼ DOWN_REGULATES	✅	-	0.82	0.82	Signor	15829723
AKT1	GSK3B	◼ PHOSPHORYLATION	✅	-	0.82	0.82	Signor	23552696

Showing 1 to 10 of 853 entries