Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H2BC21 AHSA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NEK7 TUBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AHSA1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16696853 20618441
MAPT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0709180105 18292230
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
PRKCZ AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18650932 7232391
ARIH2 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPP5C CDC37 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
PDGFRB CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10733900 6731185
ERBB2 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
CRK USP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
HSP90AA1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSP90AB1 DNAJA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22011577 21700222
DNAJA1 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2R1A EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
UBE2D2 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17635922 10514377
EIF1AD GNB2L1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ETF1 GNB2L1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PFDN6 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAP1LC3B FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 UBE2V1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FKBP4 FKBP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 27462449 11751894
NUDCD2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133715 0914307107
HSP90AA1 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP5C HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8204010 21360678
HSPA8 TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA8 PTGES3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21183720 16403413
LRRK2 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19302196
MAPT TUBA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1421571 16687396
MAPT TUBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24905733 24251416
XRCC6 PGAM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPM1A PRKAG3 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16943194 8549768
STK24 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TIPRL PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17384681
STK24 PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
TUBB TAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBE2K TRIM31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
CRK PFN1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
GNB2L1 MCTS1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
NEDD8-MDP1 UBE2NL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
TUBB4B UBE2V1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
NAA10 NACA â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
UBE2NL UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HYPK NAA10 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TUBB2A TUBB4B â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
DNJA1 AHSA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22504172 26344197
CUL3 HS90A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939624 21145461
CUL5 HS90A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21145461 19933325
HS90A NUDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20675372 19875381
FGFR3 HS90B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939624 21487019
AHSA1 DX39A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 26344197
XRCC6 ABL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 9798959
FAS AHSA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26693507 26344197
AHSA1 LDHB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26693507 26344197
AHSA1 EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
RIPK4 CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26972000 29435596
CFTR CDC37 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CDC37 ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25036637 24189400
CFTR FAS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CIAO1 GLRX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27519415 23891004
CUL3 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22709582 21145461
LRRK2 DFFA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
EGFR FKBP4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
EPHA1 PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TAB1 MAP3K7 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 5218828 16845370
XRCC5 NAA15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 12145306
TUBB2A TUBB4B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
XRCC5 YARS â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CHORDC1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
GMFB PPM1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EGFR DNJA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657067 24797263 23956138
HDAC6 DNJA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23703321 30009671 26496610 23752268
HDAC6 HS90A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15937340 19158084 18591380 17851643 23703321 15916966 22367781
RIPK4 HS90A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26972000 33961781 29435596
LRRK2 HS90B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20642453 31046837 23075850 24947832 17400507
CDC37 FKBP5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
PPP5C HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 27880917
HSP90AA1 TTC4 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
HS90A LRRK2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16321986 20642453 22612223 19536328 19826009 31046837 20949042 23075850 26355680 24947832 17400507 18367605 29519959
CFTR HS90B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
AHSA1 FKBP4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25036637 22504172
PKN2 AKT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10926925
CHORDC1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HSP90AB1 HSPA8 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
GNB2L1 GSPT1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
KIF5B TUBA1B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
TUBA1B TUBB4B â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ATG3 GABARAPL2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
NEK6 NEK7 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CRBN GSPT1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
OTUB1 UBE2V2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EIF5A PFN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
GRK6 HS90B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19996089 22939624 32707033
CFTR AHSA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338 18556464
CFTR PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
CFTR XRCC5 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
HSP90AA1 PPID â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
NAA50 NAA10 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 16507339 19480662
SPATA5 SPATA5L1 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
SPATA5 SPATA5L1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
HYPK NAA50 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
KIF5B TUBB2A â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
PARK2 UBE2G1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
TAB1 HS90A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 19875381
HS90B CUL3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939624 21145461
ABL1 ERBB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22973453 16273093 19275932
AKT1 FAS â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25640309 31980649
CUL3 PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26949739 21145461
HDAC6 ERBB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
XRCC5 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20085707 12393188
FKBP5 MAPT â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
AKT1 PRKCZ â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
NAA10 NAA50 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
AKT1 CDC37 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
LRRK2 DNJA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19826009 31046837 24725412
LRRK2 CDC37 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16321986 20642453 22612223 23075850 26355680 18367605
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
PPM1G XRCC6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28330616 30585729
CFTR HSPA8 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDC37 LRRK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HSP90AB1 MAPT â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TUBB TUBB2A â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PPP2R1A PPP2R4 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TUBB3 TUBB4B â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
EGFR HSPA8 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HS90A FAS â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31536960 16263121 31273033 21360678
FKBP4 HS90B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28514442 25036637 21170051 21730179
CDC37 AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31980649 24869908 22504172 12176997
MAP1B LRRK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21159966 24754922
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
TUBB TUBB2A â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
XRCC5 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
OTUB1 UBE2D2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
DNAJA1 HSPA8 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HSPA8 MAPT â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PARK2 UBE2D2 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
FKBP4 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
DNJA1 CFTR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29924966 10075921 26618866 31324722 11146634 17110338
PPID HS90A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21146485 10642522 12145316 20661446 20188096
HS90A FKBP4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25036637 10642522 22504172 21170051 20661446 20188096 19875381 22678819 28514442 22863883 21360678
HS90B ERBB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20650008 28369073 22939624 24189400
HS90B AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20650008 31980649 10995457
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR CDC37 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25036637 31980649 23956138 24189400 12471035
PPP2R1A CFTR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
CFTR PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
EGFR TAB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18271526 31980649 25402006 24658140
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
UBE2D2 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8379996 22124327
MAPT TUBB3 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
FKBP5 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 20048054 10642522 12538866 28363942 9001212 21170051 20661446 21235734 19875381 22863883 23999428 21360678 29079741
AHSA1 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12504007 25036637 26804907 22315411 27353360 27187154 26344197 33571422 24462205 22504172 20226818 12604615 26693507 19875381 20159553 25486457
EGFR HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 23956138 20029029 12006493 25402006 16849543 16024644 24189400 12471035 32669362
ERBB2 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 26804907 17239458 22315411 18655187 24658140 23995768 21503962 24189400 20558745 11071886 12006493 20159553 22939624 16144943 21812426
FKBP5 HS90B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 21170051 30382094
EGFR HS90B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15657067 24658140 31980649 24189400 23956138 25402006 20029029 22939624 12471035
GCH1 CDC37 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HSPA8 CFTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
EGFR CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10595738 9480911 9642287 24658140 31980649 11956190 16729043 22973453 8875975 25402006 9617486 16273093 12198159
NUDT3 DNAJA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LRRK2 DNM1L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24282027 22228096 22639965 23813973 29541021
DYNC1I2 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
HSPA8 FKBP4 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 18635947 15381148 15159550
HSP90AA1 FKBPL â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
HSP90AB1 FKBPL â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15664193 9844631 20018861
HSPA8 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 25961502 2799391 2204156
MAP2K7 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15837794 8533096 16186825
PPP5C MAP3K7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP2CA MAP3K7 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 608155200 17079228 8204431
UBE2N MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17965022 17079228 10702308
XRCC5 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 22404984 15520013 21679440 26446488 26344197 17308091 15941674 28154079 16857680 20711232 19303849 20023628 15758953 20085707 10750018 10446239 33005030 9312071 28345663 12393188
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
ATG3 MAP1LC3B â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ERBB2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
TUBB TUBB3 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
TUBA1B TUBB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
HYPK NAA10 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
PFDN5 PFDN6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
TUBA1B TUBB2A â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
TUBB2A TUBB3 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
HSP90AA1 HSPA8 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
BOLA2 GLRX3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 27519415 32296183
GART MTHFD1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
HSP90AB1 PTGES3 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
KIF5B KLC1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
AKT1 HS90A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10995457 31980649 12586360 21767636 15843522 22504172 25714412 16027165 12176997 29311840 19356729 16189514 32707033 29139175
HS90B AHSA1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 25036637 26344197 30382094 20226818 26693507 20618441 25486457
GLRX3 CIAPIN1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8153045 21516116
ERBB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 5218411 16516204
UBE2N UBE2NL â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
HS90A TTC4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 25036637 21360678 19875381
HS90B TTC4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 25036637 18320024
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
TUBA1B TUBB2A â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
AHSA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
NAA10 NAA50 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
HSP90AA1 PPP5C â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
PPP2CA PPP2R4 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
AHSA1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
CDC37 HS90A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21871133 25036637 33961781 27353360 22729780 26496610 19875381 12930845 9685350 15647277 16335536 25486457 24462205 22504172 22939624 22315411 12176997 20159553 24292678 24189400 21360678 26804907 15001580 11413142 21745565 14718169 16611982
CDC37 HS90B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28215707 25036637 33961781 26496610 11036079 22939624 23428871 27339980 24189400 25486457
CIAPIN1 GLRX3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ABL1 CRK â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
MAPT PPP2CA â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
PPP2CA TIPRL â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
HS90A HS90B â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 31536960 25036637 33961781 26344197 26496610 20353823 19875381 22863883 21360678
HYPK NAA15 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
OTUB1 UBE2N â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
HSP90AA1 PTGES3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
EGFR ERBB2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EEF2 GNB2L1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
NAA15 NAA50 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
PPID HS90B â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 21146485 16650407 15497503
NAA10 NAA15 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1A STK24 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CDC37 HSP90AB1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ETF1 GSPT1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PPP2CA STK24 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CDC37 HSP90AA1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PFDN5 PFDN6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 CRK â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
ABL1 AHSA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 26235616 27515256 29127155 26693507
ABL1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15686624 9109492 9295282 9312071
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL1 PDGFRB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 14993293 19275932 20841568
ABL1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 100.0 1.0 Omnipath 8978305 9747873 9480991 19426560 17081983 23124138 16522685 16713569 20841568 18768933 8875975 25860930 21779437 19534553 16187300 17515907 21602891 16267043 20068231 10592173 17570479 8194526 7926767 11080615 25381819 12198159 9642287 15696159 18619508 18835194 11956190 22848689 11314030 9480911 19001122 19402756 20697350 12384576 24412932 7542925 11380621 12799422 19380743 12955086 17474147 17016520
AHSA1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 25036637 16696853 17145710 19875381 12604615 24462205 26693507 26804907 22315411 12504007 20226818 20159553 22504172
AHSA1 GCH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 16696853
PRKDC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 318.0 1.0 Omnipath 27120806 14555685 20028775 20176926 11287317 27542271 26740621 11731414 12393602 34197700 17993646 21940452 21946537 11278872 22975685 16908595 18316359 34073781 24735537 18039660 24652283 20856200 26170313 21300025 15388791 19144640 26297026 17545609 33941854 16280327 10625301 33845796 25918246 34385295 17537996 14645219 20804212 15084259 12169689 21795477 22071574 23913047 34021259 21695150 15684384 33958720 14530366 16670089 19487463 19223464 17303569 25481872 15475446 17116771 28967905 33753495 12438236 29562639 16753042 33836561 19073147 15169778 16891474 19477925 16338973 16397245 34562454 15821749 33767437 34087103 11409731 18381446 15737995 27481935 11313365 26700621 17210635 25447541 33931486 17827393 17126298 15262962 28542588 33574930 11821945 20471940 15461589 17077177 33579227 26921343 17386266 33744230 26848618 12944390 33566837 26902421 21042280 21763421 34380642 18321849 14593122 25775124 25739674 17229808 26351843 24102046 23757022 33532186 16043647 24632620 12781924 25738875 10864894 17974989 25719244 15806160 16497987 25851605 20501647 18439899 28209968 10973320 24819169 25745998 34383763 19592491 19244117 19204084 29088759 26871475 34257082 26755732 17237292 17709744 17640984 34405859 18480058 33995548 22310280 20211239 12052823 22580611 31937616 19920202 26745759 15905173 12499277 15028555 27162341 21106850 33562475 30065170 23462102 15678105 15642728 27065332 28558072 28977846 15319269 21339742 15855334 21045808 20145118 21297104 18632646 17379600 15471950 23474758 26887938 11375271 20013032 18701889 16540596 15314172 28515473 15964826 19638206 25892239 28692056 20530876 27505672 25100728 21242970 17297446 10542266 14670178 15548374 33741342 12429574 11002428 15831486 17116756 25435370 32833881 11402048 25361894 15207915 20729916 15625077 18677106 12869565 11250155 21356307 15967841 31936857 25943101 18394555 12644590 14500543 18691549 27197158 15623569 33477794 12062056 16754797 15383526 21909137 21949775 20085797 16807298 15899889 33868961 23940660 23434580 33927349 23899556 14990993 12000752 27880719 26065416 19060924 34520759 14679308 15334055 17283158 25257795 17548608 30586628 24437487 20124472 15289327 23325788 21208159 33664452 31679687 12791703 15047712 17166829 26146988 17329400 20660158 21532621 21806543 20179209 25661488 20957047 17562705 19915805 12606948 17277771 10377409 25893295 17270736 16407838 20597130 15047168 28658616 16357520 15537647 12818176 11425855 17210830 19800394 12506011 21310961 16963136 21996732 15695828 33835469 11701613 19010331 26686089 28915558 15467762 17586693 18456663 34381564 18765673 20233713 34208786 11029403 22084251 20622007 12077256 11313948 16917505 19448664 27391337 15792956 21172654 15608670 12438239 19875458 22014578 25071014 11809760 18728186 31391321 33891611 19805619 33407730 25868858 25320242 34348155 20832730
PRKCZ AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11585925 15884057 14560023 16189514 11748077 18353613 11723139 10085094
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 IMPDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10930578 16713569
ATG3 MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20562859 11825910 17145710 16303767 11100732 11265251 17227760
ATG3 GABARAPL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20562859 17145710 17353931 16303767
PPP5C CDC37 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21360678 18922470
HSPA8 CFTR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21148293 10666020 19878303 21697503
CRK FLT4 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
CRK FLT4 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
CRK FLT4 â—¼   ENZYMATIC_REACTION ✅ 56.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11335727 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15308668 15501236 15520864 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16887996 17086423 17496910 17673906 17883421 18835194 19414323 19449109 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
PDGFRB CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 19426560 10733900 16713569 27686861
HSPA8 DNAJA1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 20084477 20809635 24012426 7828728 20072699
PPP2CA EEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8386634 2555220 2176079
EGFR MEMO1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18045866 20937854 21840311 15156151
PPP2CA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
EGFR ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 65.0 1.0 Omnipath 17081983 16207817 21044682 17148612 24557338 16713569 21203579 10233167 20471394 17389395 17486068 21278786 11500516 11279155 11500850 17426253 16843263 19650109 25241761 24189400 15657067 17307140 18803307 1706616 12354693 10572067 24355130 11408594 19060928 12648464 16516204 15951569 23436906 20211985
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23956138 23178489 18237807 18789131
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
PTGES3 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 16565516 10642522 11447118 26804907 15916966 11413142 16403413 21988832 11812147 19875381 19740745 14761955 12077419 10811660 20039095 22806877 25036637 20048054 19996313 18285346 20661446 22315411 23022381 18172314 20159553 22729780 22504172 16289154 9817749 14987994 8114727
HSP90AA1 PPP5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10400612 16531226 21360678 15577939 15383005
LRRK2 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22924508 24113872 26123245 24165324 25977830 22303461
PPP2CA MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945 20626350
MAP3K7 MAP2K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 17110930 17709393 25241761 9890973
TAB1 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16289117 18180283 10838074 24912525 23934659 10882101 19556242 11259596 19026643 14670075 17299140 23331499 22158122 12372426 21903422 17560374 21071413 23180781 19775907 14743216 17348859 20200282 26432169 18988627 10094049 8638164 11809792 10702308 25241761 19232515 14633987 18456659 10921914 20538596 15590691 16845370 27468689 12975377 12242293 17172402 22167179 12429732 12624112 12859960 16260783 11460167
PPP2CA MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18299321 17079228
PPP5C MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 15546861 12435421 14690518 1330687 16262633
OTUB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22367539 21130715 24145445 21763684 35500217
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP5C PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14734805
SGTA PRNP â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 23533635 28104892 23129660 23246001 25179605
XRCC5 UBE2N â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 UBE2N â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215
XRCC6 UBE2V2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 UBE2V2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368