GRB2
|
EPPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
KDELR1
|
COPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0811631106
19109439
|
CRK
|
USP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
CRK
|
FLNC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
CTSH
|
DYNC1H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
XRCC5
|
DDB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20368362
|
DDX42
|
U2SURP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
EZH2
|
PC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
23624931
21465172
|
FKBP5
|
PYGB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
FLNC
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
SLC25A3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PLEC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
KRT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
KRT18
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
RPL26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
TUFM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
HNRNPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
RPL23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
MCCC1
|
IREB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
KRT18
|
PLEC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PLEC
|
KRT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
RPL23
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ZMYND11
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7556586
20138174
|
USP53
|
TRAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
CRK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
NOP14
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
DDX24
|
GTPBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
IMP3
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
IMP3
|
NOP56
|
â—¼ PHYSICAL_INTERACTION
|
|
|
815.0
|
0.81
|
STRING
|
36370105
|
NOP14
|
NOP56
|
â—¼ PHYSICAL_INTERACTION
|
|
|
815.0
|
0.81
|
STRING
|
36370105
|
DDX18
|
RBM28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24981860
26344197
|
FTSJ3
|
NOP56
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
XRCC5
|
RFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26344197
12393188
|
FBL
|
FTSJ3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
828.0
|
0.82
|
STRING
|
36370105
|
GRB2
|
DNM1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
5217666
15834155
|
FBL
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
RPL26
|
RPS6
|
â—¼ CORRELATES
|
|
+
|
0.83
|
0.83
|
CCLE
|
31978347
|
CHAMP1
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
DDB2
|
ZMYND11
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.83
|
0.83
|
PKG
|
28854368
|
IMP3
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
GTPBP4
|
NOC2L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
NOP56
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
FBL
|
NOP56
|
â—¼ CORRELATES
|
|
+
|
0.85
|
0.85
|
CCLE
|
31978347
|
CRKL
|
USP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HuRI
|
32296183
|
TRIM25
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
GTPBP4
|
RPL26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
GNL2
|
RPL26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
FBL
|
IMP3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.86
|
STRING
|
36370105
|
DDX24
|
NOP56
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26496610
26344197
34079125
|
NOP56
|
RBM28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26496610
12777385
34079125
|
GTPBP4
|
RPL23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
ACACA
|
ACACB
|
â—¼ CORRELATES
|
|
+
|
0.87
|
0.87
|
CCLE
|
31978347
|
FBL
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
KRT18
|
KRT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
NOP56
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
MCM4
|
MCM7
|
â—¼ CORRELATES
|
|
+
|
0.89
|
0.89
|
CCLE
|
31978347
|
RPL26
|
RPL5
|
â—¼ CORRELATES
|
|
+
|
0.89
|
0.89
|
CCLE
|
31978347
|
PSMA6
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
GNL2
|
RPL23
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
DNM1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
IMP3
|
NOP14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
NOP56
|
NOC2L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
26496610
34079125
|
GNL2
|
RPL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
935.0
|
0.93
|
STRING
|
36370105
|
DDB2
|
SUGP2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.93
|
0.93
|
PKG
|
28854368
|
DDX18
|
GTPBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
FBL
|
NOP14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
GTPBP4
|
RPL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
947.0
|
0.94
|
STRING
|
36370105
|
DDX18
|
DDX24
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.94
|
STRING
|
36370105
|
DDX18
|
NOP56
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
26496610
26344197
34079125
|
RPL26
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
RPL26
|
RPL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
RPL23
|
RPL26
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
RPL26
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
GNL2
|
GTPBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.98
|
STRING
|
36370105
|
FBL
|
NOP56
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
RPL5
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
MCM4
|
MCM7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RPL23
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RPL5
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RPL23
|
RPS15A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RPL23
|
RPL5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
RPS15A
|
RPS6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CRK
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
GRB2
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRK
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CRK
|
CRKL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
84.0
|
1.0
|
ACSN
|
10022831
10086337
10426994
10567412
10811803
10849428
10982827
11062502
11166270
11335727
11353765
11385609
11447289
11449354
11526404
11532940
11579131
11687500
11777939
11907067
11960372
12175651
12393695
12629515
12640133
12670391
13678960
15099563
15111329
15169881
15308668
15501236
15520864
15536084
15567848
15573129
15574420
16000375
16002046
16076871
16530705
16572188
16582911
16713974
16887996
17086423
17397400
17496910
17673906
17883421
18250477
18287025
18835194
19109239
19414323
19449109
19454690
19909365
20189481
20805416
21149606
21372296
21826665
22064427
22461508
22464172
23087689
23390297
23523669
24217602
24346288
24751819
24795729
25922287
25960930
26201938
26552706
7682895
8551221
8837607
9157999
9314552
9570538
9753319
|
CAMK2A
|
ATP2A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7929371
|
CAMK2A
|
SYNGAP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
14970204
12951199
11278737
15358237
15312654
9620694
|
GRB2
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
DNM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
21.0
|
1.0
|
Omnipath
|
8402898
9009162
10206341
11877424
17244534
7505438
19380743
21706016
16713569
15834155
9452513
17474147
8119878
|
HNRNPA1
|
GTF2F2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
10982855
9858549
1906035
9271388
|
MCM7
|
MCM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM7
|
MCM4
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
XRCC5
|
RAD50
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
22179609
11493912
9512523
11604075
12947387
|
DDB2
|
PCCA
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.13
|
1.13
|
PKG
|
28854368
|
DDB2
|
FLNC
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.41
|
1.4
|
PKG
|
28854368
|
MSH6
|
MSH6
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-5.12
|
5.11
|
PKG
|
28854368
|
DDB2
|
DDB2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-5.71
|
5.7
|
PKG
|
28854368
|