PLG
|
PLAT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
2318848
7199524
|
PLG
|
PLAT
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
2496749
2962641
|
PLAT
|
PLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11928826
1447176
|
ATP2A2
|
MPTX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
AIFM1
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
AIFM1
|
TNFRSF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
APBB1
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
ATF2
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11243868
19948881
|
ATF6
|
ATP2A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11595740
|
F2RL1
|
ATP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
CHRM5
|
ATP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
CCR4
|
ATP2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
ATP2A2
|
PALMD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ATP2A2
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ATP2A2
|
SLC4A4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
ATP2A2
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ATP2A2
|
TNFRSF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ATP2A2
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
ATP2A2
|
NSA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
SP1
|
CALM1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9348238
10945244
|
CALM1
|
RAC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9813038
8918462
|
CAMK2A
|
RCHY1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
5220017
17568776
|
F2RL1
|
CANX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
CFTR
|
CANX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12208510
5215704
|
CANX
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
CANX
|
RNF113A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
TFDP1
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14618416
|
PIN1
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11774038
16713569
|
CUL3
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HGS
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20308550
0911188107
|
SH3BGRL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16729043
5218694
|
STAT3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731598
14966128
|
EGFR
|
RAB7A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18776048
0806158105
|
EGFR
|
KPNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20692258
7987951
|
EGR1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11830539
|
SP1
|
EGR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20121949
7384875
|
EGR1
|
PLAU
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21283769
|
EGR1
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20417179
19557503
|
STAT3
|
EGR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17129668
|
EGR1
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12011097
|
ESR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
11279135
|
EP300
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20339243
21467818
|
EP300
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12371907
11796223
|
STAT3
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
ESR1
|
WFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ESR1
|
RAC1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21118977
11060289
|
ESR1
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21920899
23658738
|
ESR1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16144913
|
ESR1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
3677090
|
ESR1
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16144913
|
F2RL1
|
WFS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
G3BP1
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ZFPM2
|
GATA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18577233
15220332
|
RHOA
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22758628
12878473
|
HAX1
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
HAX1
|
TNFRSF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
PKN2
|
HDAC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7710096
20188095
|
HDAC5
|
MEF2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10748098
15194749
|
RYBP
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
VCP
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PALMD
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RXRG
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPARA
|
HTT
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SP1
|
ILK
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19176380
24361375
|
SP1
|
KLF8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18353772
|
STAT3
|
KPNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19084525
6979076
|
LRRK2
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19302196
|
MYC
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15466196
12080469
|
STAT3
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22943793
15810077
|
MYC
|
TFDP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11139609
|
TGOLN2
|
NCSTN
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
18201567
6174903
|
NTRK1
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17389358
0701402104
|
WFS1
|
P2RY6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
WFS1
|
PALMD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SP1
|
PDHA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8476854
|
PLAU
|
PLAT
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7721771
16189514
|
RXRG
|
PPARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
VCP
|
PPARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PPARG
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11861425
11426586
|
TNF
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22078880
20651683
|
SP1
|
PSEN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10446206
|
PSEN1
|
TRAF6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19012753
18996842
|
RNF126
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
VCP
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
14743216
5216883
|
RYBP
|
TFDP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
810.0
|
0.81
|
STRING
|
36370105
|
LRRK2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
LRRK2
|
AIFM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31046837
24725412
|
CFTR
|
AIFM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26618866
17110338
|
EP300
|
ATF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24069158
10327051
|
MYC
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
CFTR
|
HAX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26618866
17110338
|
PDK3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
20029029
|
EP300
|
KLF8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
35140242
20107328
|
LRRK2
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21454543
31046837
|
MYC
|
TFAM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21150319
29467282
|
PPARA
|
RXRG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
16169070
22205725
|
RXRG
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
SIRT1
|
EP300
|
â—¼ DEACETYLATION
|
✅
|
-
|
0.83
|
0.83
|
Signor
|
19047049
|
EP300
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
PSEN1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
HDAC5
|
MEF2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
836.0
|
0.83
|
STRING
|
36370105
|
MYC
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
SP1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.83
|
STRING
|
36370105
|
AIFM1
|
HAX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
29568061
34079125
|
ATP2A2
|
PLN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
DERL1
|
CFTR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
26618866
16954204
16901789
18555783
|
EGR1
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12569082
20121949
|
ESR1
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9121466
23403292
9717844
|
PPARG
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
CAMK2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
846.0
|
0.84
|
STRING
|
36370105
|
CALM1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
EGR1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
ILK
|
HAX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25852190
23455922
32707033
|
ILK
|
AIFM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25852190
23455922
|
ESR1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23874500
11429412
|
ESR1
|
MEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
31527615
16651450
|
RAC1
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21454543
31046837
|
RAC1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11021801
16189514
|
ULK1
|
RB1CC1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
8428476
23392225
|
TRAF6
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
33201521
23524951
|
EGFR
|
HGS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
STAT3
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
22693070
|
GATA4
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
18252717
27208796
11481322
|
MYC
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12776737
16287840
32140074
15616592
16126174
17157259
|
G3BP2
|
G3BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
26777405
24981860
29395067
26186194
28514442
|
GATA4
|
ZFPM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
G3BP1
|
G3BP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CALM1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
EP300
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
EP300
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
PDK3
|
PDHA1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
11485553
|
TRAF6
|
ZRANB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
EP300
|
PPARG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11887937
17284441
20935677
28065597
16713569
|
SP1
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10651903
34252870
16478997
11030335
11517158
15647279
17623675
17906698
28425985
32115405
31536933
12200149
24530506
23714681
10362258
22415975
16734381
19062177
10899165
|
EP300
|
PPARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
18797151
9407140
10336495
|
MAP1B
|
LRRK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
21159966
24754922
|
RXRB
|
PPARG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
20211142
22205725
25609649
15604093
30699358
|
PPARA
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
SPRTN
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
HTT
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
CANX
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
MDM2
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12897156
17545634
10766163
11178989
16713569
31012223
|
SP1
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10361124
10393239
16713569
18270252
|
CFTR
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
891.0
|
0.89
|
STRING
|
36370105
|
PIN1
|
ZBTB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HuRI
|
32296183
|
PCNA
|
MAD2L2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
15254543
16819516
15199127
|
TFDP1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7734951
14618416
|
PPARG
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
17389773
14764597
19673929
|
PLG
|
PLAU
|
â—¼ CLEAVAGE
|
✅
|
|
3.0
|
0.9
|
Reactome
|
2521625
2935528
1829461
|
PLAU
|
PLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
3920216
2829380
4226004
|
SP1
|
ATF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2145272
12760745
|
ATF2
|
PLAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8647095
11179965
|
EGR1
|
ATP2A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10625299
8977381
18612190
|
PPARG
|
ATP2A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22240811
18071073
|
EGFR
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
18271526
15657067
24658140
31980649
23956138
25402006
|
VCP
|
DERL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17145710
15215856
|
EGFR
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
STAT3
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18367518
21590492
23504318
|
EP300
|
EGR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9806899
20089040
15225550
20018936
|
MDM2
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9809062
11070080
16713569
|
ERBB2
|
RHOA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18955552
20937854
15156151
|
GATA4
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19276186
|
STAT3
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21546410
|
RXRA
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9841885
9717844
|
ESR1
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9841885
9717844
|
SP1
|
HTT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22399227
20018729
|
SP1
|
KLF8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18353772
|
MYC
|
MEN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
PLAU
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20123981
17382917
22550094
|
MYC
|
RHOA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22159222
20383141
22235332
|
MYC
|
PDHA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
RPS6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11274368
16713569
|
SP1
|
NTRK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19656944
19643914
21123453
|
RXRA
|
PLAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19538480
|
RXRA
|
PPARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15888456
12562861
7760852
34081964
10195690
22205725
23711995
16189514
|
RXRB
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8384714
23331499
11237216
|
PPARG
|
TNF
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
10432118
17681149
23390297
|
SIRT1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15850715
21633182
|
SP1
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23843607
20160399
23704280
|
SP1
|
TNFRSF1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22019592
8954938
22615874
|
SP7
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17206379
16314050
24158144
|
VCP
|
SPRTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22902628
23042605
23042607
|
VCP
|
DERL1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
15215856
|
ESR1
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
EP300
|
MEF2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
ULK1
|
RB1CC1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.9
|
0.9
|
Signor
|
19597335
|
EP300
|
SP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
TNFRSF1A
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
EP300
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
EGFR
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
CAMK2A
|
RAB28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CANX
|
RAB28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ERLIN2
|
RAB28
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
ERBB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5218411
16516204
|
RB1CC1
|
ULK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
951.0
|
0.95
|
STRING
|
36370105
|
PCNA
|
SPRTN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
DERL1
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
TNF
|
TNFRSF1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
PPARG
|
RXRA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
EGFR
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
NCSTN
|
PSEN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
MYC
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7597041
18358094
22911891
18809243
1280813111085504
11085504
|
EGFR
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
21220489
24655521
23542172
29140271
28157503
26725162
22238610
25825764
17115032
26719139
28102297
22692198
28666590
25073158
20670598
20587074
23593472
25675097
|
PCNA
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18263614
11268218
16713569
|
PLAU
|
PLG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
18633355
20027185
22470492
27216177
|
SERPINF2
|
PLG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
3334852
134998
158022
2437112
|
PLG
|
F2RL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
12604689
10978167
9020112
|
ATF2
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
20068037
15356147
11490006
10748079
12509451
10688670
10318823
10913190
10954918
16888805
15546613
20018859
9826775
8816436
8552071
|
ATF6
|
ATP2A2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17991856
18360008
23850759
26587781
|
SP1
|
ATP2A2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12818568
8621466
17597815
14613864
|
CAMK2A
|
ATP2A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7929371
|
PLN
|
ATP2A2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11854448
10809745
11526231
16189514
12838339
|
CALM1
|
RAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
22944912
21299499
21730051
9199170
|
EGFR
|
CALM1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
41.0
|
1.0
|
Omnipath
|
17145710
19901323
20029029
12359306
16497976
25402006
17389395
18578522
16799092
20068231
3415247
7925415
18669648
12153558
24658140
17287340
14960328
18707149
17016520
|
CALM1
|
CAMK2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17145710
3006921
17353931
20668654
|
CAMK2A
|
RCHY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17568776
|
CAMK2A
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
17389395
17081983
3138233
20166139
10347170
15901825
16799092
18691976
8226933
20068231
1309762
7805884
92065884
1956339
7505275
18669648
15302935
|
CAMK2A
|
SLN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
32668157
19631655
27378083
23455424
|
MYC
|
CDK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18802399
2237430
8065306
11085504
|
ERBB2
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
55.0
|
1.0
|
Omnipath
|
18927589
17938195
10770932
17276342
17396146
11836499
17409144
29088738
19276355
26673326
19933706
28335434
20372791
7743995
11322924
19683496
27889260
17466630
14681223
12384528
12049736
7841526
12110582
25744022
18393321
15582998
19861462
14987992
20144215
17466629
16546994
19858290
15136770
14767478
20368335
25994202
10504341
1850698
15350223
24910099
9268380
15296723
8428596
24391510
18469858
8662825
20530684
11782384
15141014
15940258
12766774
|
CDK1
|
RXRA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
10383391
17570479
12032153
|
CDK1
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
17145710
31980649
8360196
23956138
15901825
28150246
18271526
15657067
24658140
25402006
15302935
|
CDK1
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19107194
17570479
24011073
28756945
|
CDK1
|
SP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
25398907
28831131
20150555
22266860
|
VCP
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
33444648
11733065
28115426
15652483
10811609
29153394
|
SP1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
1282800
17616668
18575762
19538880
15665278
18202149
20435036
21705183
18007664
21464950
23821666
15533438
9819401
10830317
8393457
16087726
20407012
18391986
|
ESR1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12894229
12421825
8200909
21705183
|
PPARG
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15486348
18332871
18288266
23370527
|
EGR1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16750517
15863471
23763269
16170359
11830539
17230532
|
EGFR
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
65.0
|
1.0
|
Omnipath
|
17081983
16207817
21044682
17148612
24557338
16713569
21203579
10233167
20471394
17389395
17486068
21278786
11500516
11279155
11500850
17426253
16843263
19650109
25241761
24189400
15657067
17307140
18803307
1706616
12354693
10572067
24355130
11408594
19060928
12648464
16516204
15951569
23436906
20211985
|
EGFR
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
23956138
12070153
20145033
14967450
20032199
21573184
25402006
10358079
23894143
14966128
24135280
25241761
14963038
24189400
15657067
24658140
15485908
15950906
18258752
31980649
9756944
22693070
12873986
15951569
15284024
|
EGFR
|
HGS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12953068
17016520
|
EGFR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
20809984
17284441
16713569
11887937
|
PTP4A3
|
EGR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
19945467
23691193
24376839
24686170
|
SP1
|
EGR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
20427719
18044710
9282327
8349585
10826704
10082539
12637574
|
EGR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20414733
18798221
15635605
15225550
|
EGR1
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
29212876
12011097
22455954
|
EGR1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
24337575
20653771
12509451
18675783
21841136
20332214
8773576
14767560
23872552
14722058
11856733
11739517
15640148
12560487
11997234
17537727
7918637
9407088
18157146
23632636
16317093
15659537
18651635
11520792
10913190
10419778
23184950
|
SIRT1
|
EP300
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
15632193
19047049
|
EP300
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
18782771
15509516
8756628
10205054
7530500
15653507
15735682
19506034
16285960
16713569
11322950
7499365
15649887
9590694
|
EP300
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
19.0
|
1.0
|
Omnipath
|
17145710
22290435
19623618
11804596
23343194
22761862
16039586
12776737
17157259
17143292
12660246
15576399
21151179
15522869
17306568
19407812
17666529
21285352
19619488
|
ESR1
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
24559156
16115928
16467118
17992604
19915977
15199112
21127199
21761336
21907803
20551150
11713584
1358436
20629094
18768663
19005469
9242384
20889718
10698518
16467117
|
MYC
|
ERBB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
20920219
21627565
7906953
23421821
20716114
|
ERBB2
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
23331499
15173068
|
SP1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12237165
19351845
11345900
21235772
23209644
12429135
18006846
10982795
22622808
15691879
21191649
|
ESR1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23733894
15334655
16483936
12237295
20664923
|
ESR1
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18234909
11522780
9869301
10428965
12761896
|
ESR1
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12897156
17166846
12750288
8324731
22787161
21169420
19578757
|
ESR1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
22396492
21835891
15073177
18193094
11517191
21505052
22892083
8707895
19569049
14722073
18414489
|
ZFPM2
|
GATA4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
10801815
18252717
11297508
16713569
9927675
|
HDAC5
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
10737771
10748098
11062529
12626519
|
KLF8
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
23.0
|
1.0
|
ACSN
|
11955436
11967263
12051714
15001769
15576399
16039586
17143292
17306568
17666529
17671186
17936032
19619488
19623618
20705860
21151179
21285352
22290435
22761862
23343194
24023259
25730849
7542250
8666229
|
TNFRSF1A
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
14730360
15592525
17462996
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
|
TNFRSF1B
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
15592525
17462996
18641653
18855897
19392652
21133840
21232017
21614932
23850759
24378531
|
RAC1
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11756498
11777939
12040186
12175651
12640133
12738796
14585353
15567848
15574420
15863030
16102570
16582911
16887996
17496910
17673906
18000759
18855897
19151919
19449109
19568798
21614932
24027568
26552706
27331412
7510700
8551221
|
TRADD
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
11274345
12556535
12655147
12738796
14730360
15592525
17462996
18641653
18855897
19392652
19524513
19632174
21133840
21232017
21614932
23010170
23850759
24378531
26587781
26653790
28574505
28765050
|
TNFRSF1A
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12655147
21614932
12738796
11274345
18855897
|
TRADD
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12655147
21614932
12738796
11274345
18855897
|
RAC1
|
MAP2K7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
17496910
18000759
15574420
19151919
11777939
18855897
21614932
12738796
11274345
12040186
19568798
14585353
|
MAPK7
|
MEF2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
23331499
9858528
10330143
9753748
16189514
27713878
18988627
17785444
10849446
12586839
|
MAPK7
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22046506
9461566
|
MYC
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15655352
12695333
19649205
10348347
|
SP1
|
MKI67
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21611785
22890831
22125028
20963645
|
MYC
|
PIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
MYC
|
PIN1
|
â—¼ SHARES_COMPLEX
|
|
|
22.0
|
1.0
|
ACSN
|
11274345
11283614
16713974
16940750
17558397
17873522
19131971
19366350
19751508
19836308
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
22270359
23732914
25002027
26885856
|
STAT3
|
MYC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10347215
11875494
12193690
12223527
12907458
14607900
14670306
15218058
15356132
15465827
15573129
16418395
17404308
18776941
19380816
20093776
20237412
20406969
20435894
20580461
20581311
21372296
21765015
21840487
22461508
23124025
23390297
23454751
23953057
24857661
27216177
28186502
7543512
|
MYC
|
PPARG
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10432118
11274345
11283614
11875494
16327802
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21093321
21372296
21406394
21765015
2191300
22067385
22461508
23124025
23390297
25002027
|
MYC
|
PTP4A3
|
â—¼ UP_REGULATES
|
✅
|
+
|
17.0
|
1.0
|
ACSN
|
11274345
11283613
11283614
11704864
17055429
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21406394
2191300
22067385
25002027
28536364
|
STAT3
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
19289167
17204573
18184402
22317895
20067773
15184887
15469392
10464281
9325164
20654581
21573184
17959148
22349830
9874564
20581311
19259613
|
SP1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
11470523
9492315
2284094
8437848
7753559
8355712
2057364
|
PPARG
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11973610
17462534
16405739
19075513
|
PIN1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
26655473
15048125
30723410
23716601
|
NCSTN
|
PSEN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17145710
12603837
23331499
21071413
14572442
12471034
10993067
18201567
18988627
12032140
|
PDHA1
|
PDK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
7499431
11485553
9405293
8798399
11486000
|
PDK3
|
PDHA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
44.0
|
1.0
|
Omnipath
|
17081983
20166139
18767875
17474719
7782287
19415658
15302935
11485553
20068231
19341700
82003483
18691976
18088087
16436377
7273851
12676647
20058876
11486000
18212344
|
RHOA
|
PKN2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18835241
9446575
9121475
8910519
|
SP1
|
PLAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10452548
21437359
2172788
18419748
9851700
|
SP1
|
PLAU
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23978400
10361124
21567400
21076612
|
PPARA
|
PPARG
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12941763
16226723
20706641
17261671
18769491
|
PPARA
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11009565
17463321
17260462
15669179
19039651
10377130
19640904
19576184
15891579
19225884
|
RXRA
|
PPARA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
10195690
12562861
16189514
11237216
10708554
|
PPARA
|
RXRG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22205725
23331499
16169070
15130092
|
PPARG
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
20376096
11009565
14646597
20473515
11124825
17532302
17464333
19031802
14656714
|
PPARG
|
SP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16269451
15111490
15908479
11777901
|
RXRA
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
12763030
25609649
20211142
11877444
16504037
17579352
16713569
9065481
22205725
23331499
22363753
10854698
19147680
19043829
12591919
9568716
10882139
10935544
17980149
26260846
21478865
14587029
23711995
9121466
18217139
31547433
7838715
19047629
23275339
21833030
12966085
17312272
11237216
15888456
|
RXRB
|
PPARG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22205725
25609649
23331499
20211142
15604093
11237216
18988627
10882139
|
PPARG
|
RXRG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
12615696
16189514
18988627
15130092
|
PTP4A3
|
STAT3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
47.0
|
1.0
|
ACSN
|
10347215
12223527
14607900
14670306
15218058
15356132
15573129
16418395
16540666
17192274
17409395
18268019
18471976
18776941
19380816
20093776
20237412
20406969
20581311
20609352
20681446
21053359
21084277
21811102
21840487
22073279
22677902
22825514
22970020
23124025
23178297
23454751
23691193
23953057
24030100
24376839
24403062
24857661
25139404
25687758
27036022
27216177
27222233
27452906
27526109
28186502
7543512
|
PTP4A3
|
RAC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
13.0
|
1.0
|
ACSN
|
16540666
17192274
17409395
18268019
20681446
22677902
22825514
23691193
24030100
24376839
25687758
27036022
27452906
|
PTP4A3
|
RHOA
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
13.0
|
1.0
|
ACSN
|
16540666
17192274
17409395
18268019
20681446
22677902
22825514
23691193
24030100
24376839
25687758
27036022
27452906
|
RAC1
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
23331499
26430964
16189514
11021801
|
ULK1
|
RB1CC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20562859
19225151
23392225
19597335
25686248
26118643
19211835
|
S100A1
|
TRAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
18070982
15247281
21220427
12140561
12138165
8837778
19592497
18347055
|
SP1
|
TNF
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
23733894
12759366
27030318
22534375
7649977
12509451
12378384
15175554
18357389
10829018
11390427
17897957
18218727
8258705
12560487
17047073
21320120
7918637
16847329
10559188
18930140
20068037
1618817
21784970
10688670
10913190
17307735
18467438
21411747
11500175
20221720
20701940
|
SP1
|
SPP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24240095
11126367
17689681
|
TNF
|
TRADD
|
â—¼ PHYSICAL_INTERACTION
|
|
|
65.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11279185
11280761
11438547
11460167
11875494
12531547
12646658
12811837
1330325
1431106
14607933
14625680
14660645
14730360
15099563
15310755
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
21920725
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26801188
26972597
28574505
28765050
8663014
8910423
9488730
|
TNF
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
33.0
|
1.0
|
ACSN
|
11112697
11274345
11279185
12531547
12646658
1330325
1431106
14607933
14625680
15099563
15310755
15699106
17916596
18633355
19411070
20038811
20184663
21133840
21411734
21826665
21920725
22955274
23170255
23430059
23510023
23567181
23769623
24092389
26201938
26801188
28765050
8663014
8910423
|
TNF
|
TRADD
|
â—¼ SHARES_COMPLEX
|
|
|
65.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11279185
11280761
11438547
11460167
11875494
12531547
12646658
12811837
1330325
1431106
14607933
14625680
14660645
14730360
15099563
15310755
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
21920725
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26801188
26972597
28574505
28765050
8663014
8910423
9488730
|
TNF
|
TRADD
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
65.0
|
1.0
|
ACSN
|
10925299
11003656
11112697
11274345
11279185
11280761
11438547
11460167
11875494
12531547
12646658
12811837
1330325
1431106
14607933
14625680
14660645
14730360
15099563
15310755
15592525
15699106
16713974
17301840
17462996
17916596
18264787
18633355
18641653
19392652
19411070
19524513
19632174
20038811
20184663
20435894
20531300
21133840
21232017
21411734
21826665
21920725
22955274
23010170
23170255
23430059
23508573
23510023
23567181
23769623
23850759
24092389
24378531
24699077
24958845
26201938
26587781
26653790
26801188
26972597
28574505
28765050
8663014
8910423
9488730
|
TNF
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
17145710
12887920
19287455
15485837
32196115
|
TNF
|
TNFRSF1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
56.0
|
1.0
|
Omnipath
|
17145710
19084540
11448951
12040173
8590321
14732063
7930591
9568681
2158863
8182064
9488135
11239407
14743216
24070898
7966397
7852363
17151142
8805640
7664431
15485837
2172983
1310388
15450251
1655744
19287455
1328224
|
TNF
|
TNFRSF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
98.0
|
1.0
|
Omnipath
|
17145710
19084540
8288897
11448951
23746843
22801493
14732063
2848815
9568681
2158863
8182064
9488135
23070005
20080539
11239407
26670046
14743216
21724995
21133840
24070898
25911380
7852363
2170974
17151142
26186194
27560715
25241761
23032187
24726327
20103630
8805640
11502070
19442713
3034874
23955153
18067990
22099304
15485837
22675546
12753742
1310388
12887920
19287455
10634209
2170559
1331108
24980434
22028622
|
TRADD
|
TNFRSF1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRADD
|
TNFRSF1A
|
â—¼ SHARES_COMPLEX
|
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TRADD
|
TNFRSF1A
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
60.0
|
1.0
|
ACSN
|
10465784
11112697
11274345
11279185
11668179
12048245
12531547
12556535
12646658
12655147
12738796
1330325
1431106
14607933
14625680
14730360
15099563
15170913
15310755
15592525
15699106
17462996
17496911
17916596
18633355
18641653
18855897
19392652
19411070
19524513
19632174
20038811
20184663
21133840
21232017
21411734
21614932
21826665
21920725
22955274
23010170
23070005
23170255
23430059
23510023
23567181
23769623
23850759
24092389
24378531
26201938
26587781
26653790
26801188
28574505
28765050
8663014
8910423
9379049
9582321
|
TNFRSF1A
|
TRADD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
72.0
|
1.0
|
Omnipath
|
17145710
8565075
8943045
11934887
8612133
9915703
11684708
8621670
9430227
19641494
27552911
16611992
21760970
11821416
10187805
21724995
12721308
21741934
21232017
10795740
21119000
15310755
11502070
15115707
23955153
18776134
18939944
9916731
9129204
9082980
15485837
15173123
22297296
15357952
24130170
12887920
10634209
24758719
19524513
15465831
7758105
11035039
8791485
15725726
|