Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
HSP90AA1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HSP90AB1 HIF1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18538669 6550889
HIF1A HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14726529 20068160
STUB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19940151 25637186
HSP90AB1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
HSP90AA1 HSF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11583998 9222609
HSF1 STIP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22669480 20692357
UTRN HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ICT1 NDUFAB1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PPARA PDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17669420 23867003
STAT5A PDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22698918 17360981
VCP PPARA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CCT2 CCT4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
HIF1A HSP90AB1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
PDK4 ODPA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11486000 19081061 27505672 12676647 11485553
CCT4 CCT6A â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CCT2 TCP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PDHB PDK2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
STA5A PDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STA5A ODPX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
STA5A PDK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STA5A ODP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
PDK3 ODPAT â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PDK3 ODPX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXD4 ODPX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXD4 ODPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NDUS7 ODPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31536960 34079125
ESR1 TCPE â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ACAD9 ODP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 22939629
FOXD4 ODP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 TCPD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
NDUS7 PDK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ICT1 GRSF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 20186120
FOXD4 ODPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 TCPZ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 ACAD9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
PDK3 DNLZ â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PDK3 EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
FOXD4 PDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXD4 PDK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PDK4 PDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYT12 PDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYT12 PDK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 STUB1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
STA5A ODPB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
STA5A ODPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
PDK1 ODPX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 28514442 26186194
TCPD TCPE â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 22939629 24981860 26344197
ESR1 TCPH â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 19805454 31527615
TCPH TCPQ â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26344197 22939629 22863883
TCPD TCPQ â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22939629 24981860 26344197
TCPB TCPQ â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26344197 22939629 22863883
DLDH PDK3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NDUS7 PDK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 28514442 33961781
ODPB PDK3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ODPB PDK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 28514442 26186194 33961781
ODPB PDK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ACAD9 PDK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 28514442 32877691 33961781
PDK3 TCPE â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
PDK3 TCPH â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
PDK3 TCPD â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
PDK3 TCPB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
PDK3 TCPG â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
PDK3 TCPA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
PDK3 TCPQ â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
PDK3 TCPZ â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
CCT3 CCT5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CCT5 CCT7 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
PDK3 PDK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
PDK4 PDK3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
CCT5 CCT8 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PDHB PDK1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
CCT2 CCT3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
PDK2 ODPX â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12573248 16189514 12816949
PDK2 ODPA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11486000 27505672 12676647 11485553 34079125
ODP2 PDK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16189514 11978179 12816949
HSC20 NDUS7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28380382 33957083
HSC20 PDK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28380382 33957083
HSC20 PDK3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28380382 33957083
ICT1 ACAD9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32877691 20186120
EGFR STIP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
ICT1 PDK3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32877691 20186120
HSP90AB1 HSPD1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CCT2 CCT7 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CH60 CECR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29568061 28514442 33961781
TCPE TCPH â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26344197 22939629 28514442 22863883
TCPG TCPH â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26344197 22939629 22863883 28514442 31536960
NDUS7 CH60 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29568061 28514442 33961781
TCPG TCPQ â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26344197 22939629 28514442
NDUS7 ACAD9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24344204 28514442 32877691 33961781
ACAD9 PDK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32877691
ACAD9 PDK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32877691
DLAT PDHX â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CCT2 CCT8 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PDK1 PDK3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CCT6A TCP1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
PDK3 PDHA1 â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 11485553
STA5A ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15304355 11682624
ODPAT ODPB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7864652 26344197
ODPA ODPX â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22939629 34079125
ODP2 PDK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 16189514 11978179
PDK3 CH60 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 28514442 32707033
HSC20 ACAD9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28380382 33957083
ESR1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11887937 17284441 20935677 28065597 16713569
EGFR STAT5A â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PDHA1 PDK1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PDK1 PDK2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ESR1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
ODP2 ODPX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22939629 21988832 14638692 31536960 16189514
HSC20 ODPX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24606901 28380382 33957083
PDK1 ODPA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11486000 29568061 26186194 22195962 27505672 12676647 7782287 24486017 11485553 34079125
PDK3 ODPA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 11486000 27505672 12676647 28514442 11485553 34079125
TCPE TCPQ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22863883 22939629 24981860 26344197
TCPE TCPZ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 22939629 24981860 26344197
TCPD TCPZ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22863883 22939629 24981860 26344197
TCPB TCPZ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 26344197 22939629 22863883
TCPQ TCPZ â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 26344197 32814053 22939629 22863883 30021884
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PDHX PDK1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CCT6A CCT7 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CCT6A CCT8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
HSF1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
STA5A EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 16729043 24135280 10358079 25402006 22729867
ODPX DLDH â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 32296183 16442803 16263718 26186194 28514442
TCPH TCPA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26344197 22939629 16085932 22863883 9250675
ODP2 PDK3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16189514 11978179 28514442 17683942
TCPA TCPQ â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16085932 22939629 26344197 30021884
STIP1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21170051 27353360
PDK2 PDHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16436377
PDK3 PDHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16436377
PDK1 PDHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16436377
PDK2 PDK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12573248 26496610 26186194 29568061 28514442 32707033 16189514
PDK2 PDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 12573248
CCT3 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT2 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT4 CCT8 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT3 CCT4 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ODP2 ODPA â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 26344197 22939629 14638692 16189514 34079125
CCT5 CCT6A â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PDHA1 PDHB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HIF1A HSP90AA1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ODPB DLDH â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 28514442 26186194 29128334
CCT4 TCP1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
DLAT PDHA1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
STIP1 HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ - 0.92 0.92 Signor 27353360
CCT4 CCT7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
ATM PDK3 â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
CCT7 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT8 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT3 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
TCPE TCPG â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 24981860 26344197 22939629 28514442
TCPD TCPH â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 24981860 26344197 22939629 28514442 22863883
TCPH TCPZ â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 24981860 26344197 22939629 28514442 22863883
DLDH ODP2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 26344197 22939629 26186194 28514442
TCPD TCPG â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 24981860 26344197 22939629 28514442 22863883
TCPB TCPG â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 24981860 26344197 22939629 28514442 22863883
TCPG TCPZ â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 24981860 26344197 22939629 28514442 22863883
CCT3 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
CCT7 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
ODPX ODPB â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 7864652 22939629 26186194 28514442 16189514
TCPA TCPZ â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 16085932 22939629 26344197
CCT2 CCT5 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
CCT3 CCT7 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
DLAT DLD â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
DLDH ODPA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 29128334 26186194 28514442 34079125
TCPB TCPE â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24981860 26344197 22939629 22863883 30021884
TCPE TCPA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 22939629 16097032 16085932 9250675
TCPB TCPH â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24981860 26344197 22939629 28514442 22863883 30021884
TCPB TCPD â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 32296183 24981860 26344197 22939629 30021884
TCPA TCPD â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 26344197 22939629 16085932 22863883 30021884
TCPA TCPG â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 26344197 16085932 22939629 28514442 22863883
DLD PDHB â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PDHB PDHX â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
HSP90AB1 STIP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DLAT PDK3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
HSP90AA1 STIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
DLD PDHX â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NDUFAB1 NDUFS7 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ODPA ODPB â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 19081061 26344197 29128334 7864652 22939629 12651851 26186194 28514442 31536960 16189514 34079125
ODP2 ODPB â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 26344197 18206651 26186194 14638692 28514442 16189514
TCPA TCPB â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 14532270 26344197 22939629 16097032 16085932 22863883 30021884
DLAT PDHB â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ACAD9 NDUFS7 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PDHA1 PDHB â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACAD9 NDUFS7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
ACAD9 NDUFAB1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
ATM HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 27245613 24681585 21095578 18971907 21095582 27027353 23573973 27068951 25956861 23707302 26942179
PDHA1 DLAT â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLAT PDHA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLAT PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLAT PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLAT PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLAT PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHA1 DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLD PDHA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLD PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLD PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLD PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLD PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
EGFR STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 23331499 31980649 10358079 24658140 25402006 18586824 16729043
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
STAT5A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11731618 22201800 11682624 11682625
HIF1A PDK3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A PDK1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A PDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18269201 16517405 17855495
HSF1 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9880553 21932106 10440232 19818013 20045681 20668218 15706094 17965413
HSF1 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21932106 24384723 15221402 20185824 20817212
PPARA HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 12482853 12962497
STIP1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 10642522 21235734 21360678 26804907 11413142 24949977 19875381 10786835 20704274 21170051 26496610 27353360 25036637 19996313 9452498 18285346 24462205 22315411 20159553 22729780 22504172 11877417
NDUFS7 NDUFAB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
NDUFS7 NDUFAB1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 15186778 15526035 15807660 16200211 16218961 17344420 18485875 19131594 20025615 20816094
PDHX PDHA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHA1 PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA1 PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA1 PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA1 PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK1 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19415658 15302935 11485553 20068231 19341700 22195962 82003483 18691976 18088087 16436377 7273851 12676647 20058876 11486000 18212344
PDK3 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 44.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19415658 15302935 11485553 20068231 19341700 82003483 18691976 18088087 16436377 7273851 12676647 20058876 11486000 18212344
PDK4 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 48.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19690332 19415658 15302935 11485553 19341700 82003483 18691976 18088087 16436377 17487921 7273851 12676647 18220336 11486000 19081061 18212344
PDK2 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 40.0 1.0 Omnipath 12676647 19415658 17081983 82003483 20166139 18767875 17474719 18691976 22910903 11485553 11486000 7782287 19341700 16436377 7273851 18212344 15302935
PDHA2 PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA2 PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA2 PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA2 PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK4 PDHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16436377 14966024
PDHX PDHA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHX PDHB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHB PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHB PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHB PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHB PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368