EPOR
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11443118
11124936
|
JAK2
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11443118
11124936
|
ERBB4
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16729043
5218694
|
EP300
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23353771
23285190
|
CBL
|
ERBB4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17635922
10514377
|
ESR1
|
EP300
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16704985
11279135
|
EPOR
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
8400282
|
ERBB4
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16912174
|
JAK1
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
9670964
|
EGFR
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
STA5A
|
PDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
STA5A
|
ODPX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26496610
|
STA5A
|
PDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
BTK
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
8617237
7925280
11413148
|
STA5A
|
KLHL7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
STA5A
|
ODP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
26496610
|
TLR2
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
PDK3
|
ODPX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
ESR2
|
ODP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25604459
29509190
|
PDK3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
20029029
|
PTN1
|
EPOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
14527337
|
STA5A
|
CD3Z
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
9880255
16189514
|
STA5A
|
ODPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26496610
|
STA5A
|
ODPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26496610
|
ODPB
|
PDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
ODPB
|
PDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
ESR2
|
EP300
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
18765668
11500849
|
SHC1
|
EPOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
8400282
16713569
|
BTK
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
838.0
|
0.83
|
STRING
|
36370105
|
PTN11
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
18519587
17330819
11157475
|
PTN1
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12237455
|
SHC1
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23397142
10996427
|
CBL
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
25814554
12193575
33767425
23533197
|
STA5A
|
JAK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
10037026
18250158
16189514
9047382
|
STA5A
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
12459499
26970274
16713569
|
EPOR
|
STA5B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15644415
8977232
|
PTN11
|
EPOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8639815
7534299
|
ESR2
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
11682624
|
PDK3
|
PDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
28514442
32707033
|
PDK2
|
ODPX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12573248
16189514
12816949
|
PDK2
|
ODPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
11486000
27505672
12676647
11485553
34079125
|
ODP2
|
PDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16189514
11978179
12816949
|
JAK2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16713569
11163768
|
JAK1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16713569
11163768
|
CRKL
|
PTN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9344843
9660791
23397142
|
MK01
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9528769
11358671
12093745
|
EP300
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9773981
9989503
14726487
30110629
21988832
26504087
|
EGFR
|
STA5B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11751923
22729867
16729043
10558875
|
IL2RB
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ESR1
|
ESR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
ERBB4
|
PTN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22973453
16729043
28065597
|
JAK3
|
CD3Z
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11349123
16189514
|
SHC1
|
CD3Z
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
8647168
7544002
16189514
8656061
|
STA5A
|
ERBB4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16729043
22584572
15534001
|
STA5A
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10602027
16189514
20816854
|
STA5A
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15304355
11682624
|
ODPA
|
ODPX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22939629
34079125
|
JAK2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
24240702
23838182
9363897
10358079
10635327
16273093
|
ESR1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11887937
17284441
20935677
28065597
16713569
|
CRKL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CBL
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18271526
24658140
31980649
16729043
23397142
25754235
25402006
|
NMI
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9989503
16189514
|
NMI
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11916966
16713569
|
SHC1
|
MK01
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23584453
10996427
|
STA5A
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11722592
9047382
|
ODP2
|
ODPX
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22939629
21988832
14638692
31536960
16189514
|
PDK3
|
ODPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
11486000
27505672
12676647
28514442
11485553
34079125
|
TLR2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
17126326
25402006
24658140
|
SHC1
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10602027
16189514
8294403
|
CBL
|
EGFR
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
20332299
|
EGFR
|
CBL
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
16829981
|
CRKL
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9657743
9845531
9837784
11167825
|
STA5A
|
MK01
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10194762
25241761
10996427
|
PTN11
|
JAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12403768
11036942
12270932
9794795
8995399
|
PTN11
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10617656
12060651
16189514
12237455
|
PTN11
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12270932
11223155
20473329
16729043
22973453
7673163
28065597
24935154
9756944
14560030
7588774
8959326
16273093
|
JAK2
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8617237
9575217
34197875
11413148
9047382
7925280
|
STA5A
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
24658140
31980649
16729043
24135280
10358079
25402006
22729867
|
ODP2
|
PDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
16189514
11978179
28514442
17683942
|
ESR1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11493692
27977889
10334989
11782371
16713569
17505062
15674350
19887647
20060929
11244506
16860316
17392432
31527615
16061635
16260778
12400015
1244506
25499220
29367421
|
EP300
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10655477
21212407
19887647
22787115
16713569
11782371
21102443
|
BRCA1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
900.0
|
0.9
|
STRING
|
36370105
|
JAK1
|
BTK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9178903
|
EGFR
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23158001
24797263
25872741
31182136
10635327
26055326
14505571
15210722
32714745
23774213
19155296
11370743
19836242
8665853
19947936
18271526
25140053
15668240
22394513
17486068
33323455
32377695
22203672
17182860
12604776
14627991
15383614
23153581
15735736
28541302
16849543
17242169
20562913
32904620
9121472
15677445
7782294
16923119
17995934
19531499
15465819
31959764
32114396
23457600
29629558
18316398
23799367
24714105
31120930
12061819
16713569
7657591
33617900
10086340
19225046
33762435
23175185
16729043
28791635
16246327
28198003
15962011
22266821
15117950
27059931
10428778
12734385
8662998
25005938
27903975
16969069
26177020
8798643
10799548
9756944
15159412
19578043
15657067
18255265
23418353
25754235
22976291
17545148
12803489
18319245
19713535
7592693
30544639
15107835
11994282
17971399
16105874
15282549
20940296
23897813
9130710
18273061
18508924
17880946
20124286
12593795
16914641
20877636
10092522
25521828
11408594
22591401
9890970
20308550
22833562
21772844
33627783
11239464
|
EGFR
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8524316
15284024
|
SHC1
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20935677
11773443
16713569
|
ESR2
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19022902
19746436
10706629
12630920
9473491
21182203
29509190
17991765
|
ODP2
|
ODPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
26344197
22939629
14638692
16189514
34079125
|
ERBB4
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
STA5B
|
STA5A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
28514442
9528750
|
SHC1
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
7535773
9126968
|
EP300
|
ESR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
ODPX
|
ODPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
33961781
7864652
22939629
26186194
28514442
16189514
|
JAK2
|
STA5B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
9575217
12538627
24354892
9047382
|
CRKL
|
EPOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9344843
9129019
11443118
|
PTN11
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
8912646
9442080
7559603
8639815
8995399
|
PTN1
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
11694501
11970898
15821101
|
STA5A
|
EPOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
15644415
8977232
10374881
|
SHC1
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9234717
9541596
15677445
8621719
16713569
8950973
10025673
10570290
8662998
19380743
9461587
9434624
|
CBL
|
EGFR
|
â—¼ COLOCALIZATION
|
✅
|
|
0.96
|
0.96
|
mint
|
16914641
7033849
028274
|
JAK2
|
EPOR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
14982882
12441334
8343951
11779507
|
SHC1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10595738
24797263
24658140
7542744
21278788
9130710
28065597
10766863
10635327
8034616
24430869
7518560
12577067
19531499
31959764
8810340
9742218
11196191
23799367
23956138
9756944
16713569
11370743
8665853
18271526
15657067
11408594
20473329
22973453
16729043
20935677
20067773
7506413
16273093
25754235
8610109
24189400
26551075
9388490
8887653
31980649
7542991
9544989
9020193
25187647
25402006
30544639
10049786
8662998
|
EPOR
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
EGFR
|
PTN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
7693694
24658140
31980649
11506178
10889023
9355745
12573287
8621392
9050838
25402006
7540771
25796184
|
ODPA
|
ODPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
33961781
19081061
26344197
29128334
7864652
22939629
12651851
26186194
28514442
31536960
16189514
34079125
|
ODP2
|
ODPB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
33961781
26344197
18206651
26186194
14638692
28514442
16189514
|
CBL
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
SHC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
CBL
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
SHC1
|
CRKL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRKL
|
CBL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
SHC1
|
CRKL
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
CRKL
|
CBL
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
CRKL
|
CBL
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
35.0
|
1.0
|
ACSN
|
10426994
11062502
11353765
11385609
11447289
11526404
11579131
11687500
11907067
12670391
15169881
15308668
15536084
16000375
16076871
16713974
17397400
18250477
18287025
18835194
19109239
19454690
19909365
20189481
20805416
21149606
21826665
22464172
23087689
23523669
24751819
24795729
25960930
7682895
9314552
|
EGFR
|
CRKL
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
31980649
23397142
18271526
24658140
25402006
16729043
|
BRCA1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11244506
12400015
15674350
10334989
16713569
11493692
|
TLR2
|
BTK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
21873236
11544529
22454496
16439361
15944945
12724322
17726518
|
CBL
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
188.0
|
1.0
|
Omnipath
|
34609770
16105874
18273061
22239438
24797263
20332299
17635922
23158001
17545148
8662998
12604776
9890970
23153581
17182860
25872741
12593795
23175185
10092522
15107835
22266821
22833562
24714105
17242169
25140053
20124286
19531499
9756944
10086340
22203672
19225046
16729043
15282549
20562913
22394513
20940296
23331499
7592693
19713535
10635327
19836242
15465819
15210722
25521828
23897813
10514377
12734385
18508924
11994282
20877636
33323455
22976291
23774213
23027125
15159412
18255265
16246327
28541302
16849543
23799367
16713569
10799548
8798643
19155296
9121472
17486068
21772844
16969069
15677445
15962011
23418353
12803489
32714745
14505571
27903975
19578043
26177020
11239464
18319245
11408594
10428778
12061819
17995934
17971399
27059931
26055326
15735736
23457600
7782294
22591401
29629558
11370743
7657591
21071413
28198003
18316398
19947936
9130710
18271526
15657067
31182136
16923119
17880946
32904620
15117950
14627991
15668240
15383614
|
EGFR
|
SHC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
ESR1
|
EGFR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12894229
12421825
8200909
21705183
|
JAK2
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17389395
10635327
17081983
10358079
16273093
16799092
18691976
10459005
9363897
15284024
23838182
17016520
18669648
15302935
|
EGFR
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
78.0
|
1.0
|
Omnipath
|
9544989
8808684
10595738
23956138
9388490
11350724
16273093
7542991
7681824
7518560
9710588
23799367
16713569
25402006
11370743
24797263
9742218
20935677
8887653
8034616
23331499
8662998
7542744
10049786
28065597
9130710
10635327
24189400
7506413
18271526
15657067
24658140
8810340
12577067
11196191
10766863
23178716
31980649
35384245
11408594
19531499
9756944
26551075
1623525
15951569
16729043
17956904
|
EGFR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
20809984
17284441
16713569
11887937
|
JAK2
|
EPOR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
10660611
12441334
7559499
8343951
18672044
11779507
12027890
11443118
12524467
9030561
9573010
15212693
10579919
|
ERBB4
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16273093
16729043
24658140
|
ESR2
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
14754635
24284820
15207704
18784357
11566442
12630920
22820289
19001520
18511514
14676837
19207817
22622808
21763263
18339713
15087130
|
ESR1
|
ESR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12630920
9473491
19746436
21182203
10706629
10022879
|
JAK1
|
IL2RB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
12811837
14607946
15289500
15563472
16212621
16799562
16815076
17371980
17398124
17459805
1825141
18758473
19528259
19833085
19913445
20007590
20856220
21307131
21840487
22224781
23124025
23650441
24829413
25582338
26755705
2965306
6164929
7512720
7521688
7523571
8683106
9625766
|
JAK1
|
IL2RB
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10807786
10820393
10849428
12095053
12811837
14607946
15289500
15563472
16212621
16799562
16815076
17371980
17398124
17459805
1825141
18758473
19528259
19833085
19913445
20007590
20856220
21307131
21840487
22224781
23124025
23650441
24829413
25582338
26755705
2965306
6164929
7512720
7521688
7523571
8683106
9625766
|
JAK3
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
7693677
16189514
10825200
7973659
9553136
7973657
|
JAK1
|
IL2RB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
9774657
7973658
8700888
12133952
8643566
10373548
7499411
8041779
7973659
9553136
7973657
|
IL2RB
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8294403
8700888
8643566
10602027
16189514
24737791
|
JAK1
|
JAK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
92.0
|
1.0
|
ACSN
|
10485906
11160275
11306493
11371360
11489965
11579131
11777960
11867689
11870632
11964313
12223527
12401408
12413632
12496409
12754507
12811837
12818165
1439146
14607900
14610620
14657224
15099563
15356132
15573129
15634932
15778339
15811952
15814715
16243976
16286920
16413922
16424049
16713974
17016554
17404308
17485448
17559085
17683974
18209571
18250477
1825141
18272812
18451175
18555777
18555778
19581928
19833085
20038811
20138012
20184663
20237318
20406969
20510870
20581311
20819927
20856220
21097505
21115385
21149606
21411734
21469115
21840487
22595692
22754783
23034983
23124025
23390297
23567181
24011634
24030977
24091328
24346288
24418198
24658051
25002027
25582338
26201938
26268945
26755705
27216177
27557510
2965306
6425450
7512720
7521688
7543512
7590867
8837607
9535722
9834059
9845545
9864217
|
JAK1
|
JAK2
|
â—¼ SHARES_COMPLEX
|
|
|
92.0
|
1.0
|
ACSN
|
10485906
11160275
11306493
11371360
11489965
11579131
11777960
11867689
11870632
11964313
12223527
12401408
12413632
12496409
12754507
12811837
12818165
1439146
14607900
14610620
14657224
15099563
15356132
15573129
15634932
15778339
15811952
15814715
16243976
16286920
16413922
16424049
16713974
17016554
17404308
17485448
17559085
17683974
18209571
18250477
1825141
18272812
18451175
18555777
18555778
19581928
19833085
20038811
20138012
20184663
20237318
20406969
20510870
20581311
20819927
20856220
21097505
21115385
21149606
21411734
21469115
21840487
22595692
22754783
23034983
23124025
23390297
23567181
24011634
24030977
24091328
24346288
24418198
24658051
25002027
25582338
26201938
26268945
26755705
27216177
27557510
2965306
6425450
7512720
7521688
7543512
7590867
8837607
9535722
9834059
9845545
9864217
|
JAK3
|
JAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
11641425
19901323
20135364
17259970
12207328
10825200
11909529
15659558
12559972
9553136
|
JAK2
|
SHC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9126968
7535773
|