Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
FYN CSK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7524477 6730342
LCK CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
SHC1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7516469 5220322
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
ZAP70 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211965 10556826
ZAP70 SHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15688026 5217506
CD3Z CSK â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 9172452 8621646
ATX2 CD3Z â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32814053 9575182
SLAP1 CD3Z â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10449770 16189514
STA5A CD3Z â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9880255 16189514
CSK LCK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15144186 12485116 31980649
SLAP1 ZAP70 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10449770 16189514
DOCK2 CD3Z â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25241761 12176041
TRAT1 CD3Z â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9687533 11390434 16189514
SHC1 STA5A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23397142 10996427
STA5A JAK3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10037026 18250158 16189514 9047382
ZAP70 FYN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7760813 16189514 16713569
CD3Z FYN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 1454062 1530920 8760790 8647168 16713569 9368621 7589084 16189514
TRAT1 FYN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9687533 10790433
TRAT1 LCK â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9687533 10790433
SHC1 ZAP70 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
U119A CD3Z â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14757743 16189514
LCK CD3Z â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14523017 24463463 8626561 26390156 9047237 16461343
JAK3 CD3Z â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11349123 16189514
SHC1 CD3Z â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8647168 7544002 16189514 8656061
U119A LCK â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14757743 16189514
LCK ZAP70 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SHC1 CSK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10037694 19380743 12048194
U119A FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14757743 16189514 16713569
CD3Z ZAP70 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11353765 7528772 30863395 8901551 9036949 21957439 8366117 15832366 10704231 24463463 7509083 7737297 10752619 20637659 8648092 9185620 22242145 16189514 8906806 8647168 26390156
FYN TRAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9687533
LCK JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278738 17570479 16189514
LCK TRAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9687533
CSK FYN â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
CSK LCK â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 10790433 11181701 12485116 15713798 19290918 8011291 8986721
CSK FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 1985196 8262983 11489946 16537894 9647655 25720756 18691976 10366594 19369195 1533589 1699196 7524477 16713569 15713745 14967142
CSK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12767520 12048194 18829532 9819392 19380743 10037694 17673906
CSK LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 56.0 1.0 Omnipath 20346773 19901323 10692391 11489946 22566970 24463463 2141684 16497976 15592455 20813252 10799545 14967142 27547268 24764511 28522807 16537894 12485116 8193535 24227778 17897955 8183556 22426112 89123626 15489916 14610046 23109003 18691976 28448599 17947241 1639064 12414720 15144186 27460989 24816556 22507872 8631775 15743820 25979654 8945479 11181701 27045023 25595912 15259016
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN TRAT1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 10591186 10648627 12218089 12731048 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502
SHC1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
FYN SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 96.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 16713569 9446569 17389395 23331499 18578522 10921922 10482988 10764799 18452278 20068231 10592173 18669648 12522270 9685404 10896916 7516469 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
FYN ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7760813 16713569 16839418
LCK ZAP70 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK TRAT1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 9446569 17389395 18578522 10921922 10482988 10764799 18452278 20068231 18669648 12522270 9685404 10896916 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
LCK ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 23874979 7961936 17579062 29073235 30992398 15292262 23933134 31932281 21829558 15592455 21917715 9199177 8798643 7612267 16339550 23331499 10202147 22238573 16189514 32184287 21103055 7642520 33531381 12648457 12522270 17998387 9685404 20945976 16839418 15144186 16461343 16094384 11270871 17192257 10037717 8756661 19606965 23758320 27869819 16111633 25137454 15268851 17942891 33482200 11514606 11514605 15659558 10556826 10318843
ZAP70 SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 90.0 1.0 Omnipath 19901323 7961936 9388490 20230923 9096689 16497976 9121430 15592455 9446569 10891441 17389395 11687594 18578522 10921922 10482988 10764799 18452278 20068231 16189514 18669648 12522270 9685404 10896916 9927207 15688026 12237775 8702728 8610109 19651622 9741627 8761298 9710204 19664994 17016520 10816433 11075717