Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RPS6KB1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
HTT AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
PDK1 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9512493
HTT DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HIC2 PDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPARA HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PDK2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT PDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
ISOC2 PDK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPARA PDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17669420 23867003
STAT5A PDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22698918 17360981
PDK4 ODPA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 11486000 19081061 27505672 12676647 11485553
PDHB PDK2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
STA5A PDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STA5A ODPX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
STA5A PDK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STA5A ODP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
PDK3 ODPX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXD4 ODPX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXD4 ODPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ACAD9 ODP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 22939629
FOXD4 ODP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXD4 ODPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HEMH PDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AKT3 AKT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
AKT3 FKBP5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXD4 PDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXD4 PDK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PDK4 PDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYT12 PDK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYT12 PDK3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STA5A ODPB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
STA5A ODPA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
PDK1 ODPX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 28514442 26186194
ODPB PDK3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ODPB PDK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 28514442 26186194 33961781
ODPB PDK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ACAD9 PDK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 28514442 32877691 33961781
PDK3 PDK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
PDK4 PDK3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
PDHB PDK1 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
FKBP5 HSP90AB1 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PDK2 ODPX â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12573248 16189514 12816949
PDK2 ODPA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11486000 27505672 12676647 11485553 34079125
ODP2 PDK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16189514 11978179 12816949
ACAD9 PDK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32877691
ACAD9 PDK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32877691
DLAT PDHX â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
PDK1 PDK3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
PDK3 PDHA1 â—¼   PHOSPHORYLATION ✅ - 0.87 0.87 Signor 11485553
ODPA ODPX â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22939629 34079125
ODP2 PDK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29568061 16189514 11978179
AKT1 PDK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 34278744 27505672 27166089
PDHA1 PDK1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PDK1 PDK2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
ODP2 ODPX â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22939629 21988832 14638692 31536960 16189514
PDK1 ODPA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11486000 29568061 26186194 22195962 27505672 12676647 7782287 24486017 11485553 34079125
PDK3 ODPA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 11486000 27505672 12676647 28514442 11485553 34079125
PDHX PDK1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ODP2 PDK3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16189514 11978179 28514442 17683942
PDK2 AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12162751
STIP1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21170051 27353360
PDK2 PDHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16436377
PDK3 PDHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16436377
PDK1 PDHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16436377
PDK2 PDK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12573248 26496610 26186194 29568061 28514442 32707033 16189514
PDK2 PDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 12573248
ODP2 ODPA â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 26344197 22939629 14638692 16189514 34079125
FKBP5 HSP90AA1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PDHA1 PDHB â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
DLAT PDHA1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
STIP1 HSP90AA1 â—¼   PHYSICAL_INTERACTION ✅ - 0.92 0.92 Signor 27353360
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
ODPX ODPB â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 7864652 22939629 26186194 28514442 16189514
DLAT DLD â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
HSP90AB1 SUGT1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
DLD PDHB â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
PDHB PDHX â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
HSP90AB1 STIP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
DLAT PDK3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
HSP90AA1 STIP1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
DLD PDHX â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ODPA ODPB â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 19081061 26344197 29128334 7864652 22939629 12651851 26186194 28514442 31536960 16189514 34079125
ODP2 ODPB â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 26344197 18206651 26186194 14638692 28514442 16189514
DLAT PDHB â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
HSP90AA1 SUGT1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PDHA1 PDHB â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ACAD9 NDUFAB1 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 10465784 15526035 16200211 16218961 17344420 20025615 20816094 25371197 26989860
STAT5A AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 24218138 24469394 18042802 20385773
PDK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12176337 15743829 12682057 11445557 15899889 12149249 10833263 15718470 11278835 10226025 11087733 14500673 16341064 19897009 9368760 24012393 11825911 9512493 9736715 11313365 9868760 15364915
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
PDK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19951971 24931005 16341064 10438924 21998731 29562639 11369519 23006971
AKT1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11943559 23331499 25241761 21071413 12183455 15149849 11438723
PDHA1 DLAT â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLAT PDHA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLAT PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLAT PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLAT PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLAT PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHA1 DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLD PDHA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
DLD PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLD PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLD PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
DLD PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PPARA HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16189514 12482853 12962497
STIP1 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 10642522 21235734 21360678 26804907 11413142 24949977 19875381 10786835 20704274 21170051 26496610 27353360 25036637 19996313 9452498 18285346 24462205 22315411 20159553 22729780 22504172 11877417
NEK6 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11516946 25093993 12023960
PDHX PDHA1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHA1 PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA1 PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA1 PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA1 PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK1 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19415658 15302935 11485553 20068231 19341700 22195962 82003483 18691976 18088087 16436377 7273851 12676647 20058876 11486000 18212344
PDK3 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 44.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19415658 15302935 11485553 20068231 19341700 82003483 18691976 18088087 16436377 7273851 12676647 20058876 11486000 18212344
PDK4 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 48.0 1.0 Omnipath 17081983 20166139 18767875 17474719 7782287 19690332 19415658 15302935 11485553 19341700 82003483 18691976 18088087 16436377 17487921 7273851 12676647 18220336 11486000 19081061 18212344
PDK2 PDHA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 40.0 1.0 Omnipath 12676647 19415658 17081983 82003483 20166139 18767875 17474719 18691976 22910903 11485553 11486000 7782287 19341700 16436377 7273851 18212344 15302935
PDHA2 PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA2 PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA2 PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHA2 PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK4 PDHA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16436377 14966024
PDHX PDHA2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHX PDHB â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
PDHB PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHB PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHB PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHB PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX PDK3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX PDK2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX PDK4 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDHX PDK1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7499431 11485553 9405293 8798399 11486000
PDK1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 11914378 17110931 12370290 15388791 15718470 16286006 20068231 9465032 15809305 16099428 14560963 11279232 9271440 9445476 18669648