Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
STAT3 BCL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11994401
BCL2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15210690
ERF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17699159 17525531
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
PTPRR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17360477
ERF JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15722512 12533699
JUN MBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20720108 11226757
ESR1 TSC2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 15039427 15851513
MK01 TNR1A â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11606045 19850087
LCK LZTS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 25416956
MYC JUN â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
JUN P53 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31182485 25609649
FOS ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
TRI25 MK01 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29117863 31980649
MK01 IPP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 31980649
MK01 CXA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 12637502 9535909 29931708 9535905 8631994
MK01 GCC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 31980649
PTPRR DHYS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27432908 27880917
PTN7 DHYS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28675297 27880917
MYC MP2K1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 7957875 26496610
RAF1 LCK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 8939988
MK01 LCK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 8626561 8506364 15967991 8618896
P53 SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12732139 23687300 24157709
ARRB2 MK03 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 12473660
ARRB2 M3K1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 17620599
MK01 VAV â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9013873 8900182
MK14 ERF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DUS7 DUS9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LCK STAT3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 25814554 10825200 18070987
SHC1 STA5A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23397142 10996427
VAV RAF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 8900182
MK03 P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21187340 10958792 21147777 16713569
P53 MK14 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10581258 20213747 17172861 15642743 21675959 21050851
MK03 MYC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9155018 15210690
MK01 STAT3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12763138 15979846 10521505 9872331 9343414 11350938 12576423 10446219 14551213
MK01 ARRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11226259 25241761 15699045 17620599
PAXI MK01 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 14636584 25241761 24706358
MK01 ERF â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 33961781 31980649 10330152
MK01 SYUA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11279280 12121974
PEA15 MK03 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11702783 32296183 33961781 21900206
KS6A2 KS6A3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 33961781 31980649
MK01 BCL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10567572 12039864 15225643
LZTS2 MK01 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 32296183 31980649
ESR1 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
SHC1 PAXI â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 31980649
MK01 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19914168 10197981 16156666 18729074
PEBP1 MK01 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10490027 10757792
DUS7 MK01 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28675297 33961781 9788880
MK01 IEX1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16456541 12356731
MK01 ANDR â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10318905 9725910
BCL2 RAF1 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
MK01 ESR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9528769 11358671 12093745
HMMR MK01 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33961781 31980649 11403955
PTPC1 MK01 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28675297 32296183 33961781 27880917
MK14 PTN7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 25241761 27880917 10206983 10415025 28675297 27432908 12413699 10559944
MP2K1 M3K1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 14500727 10969079 17110930
JUN STAT3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10490649 16713569
MK01 TSC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15851026 15342917
TSC2 KS6A1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15757502 15342917
FOS SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21829441 9732876
STA5A ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15304355 11682624
DUS3 MK01 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12840032 10224087
DUS9 MK01 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31980649 27880917 9596579 11988087 21908610 33961781 28675297 27432908
KS6A6 MK01 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31678930 33961781
MK01 DHYS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 31980649
MK01 MAPK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15094067 21675959 12861023 8995385
MK03 DUS3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12840032 10224087
DUS9 MK14 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32707033 27880917 9596579 11988087 21908610 33961781 26186194 23602568 28675297 27432908
KS6A1 KS6A3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 23455922 31980649 33961781
PEA15 KS6A3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22213050 12796492
MP2K1 MP2K2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32707033 33961781 10409742
KS6A1 KS6A2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 23455922 31980649 33961781
PEBP1 RAF1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
MYC MK01 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15210690 9207092 31638140 7957875 29467282
MYC P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28628118 28205554
SHC1 MK01 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23584453 10996427
JUN ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17317669 11477071 16713569 23747343
JUN MK01 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10419510 29225075 1922387 25609649 11431474
MK03 MKNK1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 9155018
P53 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 26556313 10766163 17545634 21761334
MK01 TOB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12151396 12050114
MK01 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10958792 25241761 11409876 21147777 23443559 15867353 12091386 21675959 15116093
MK01 DUS16 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11489891 12794087
DUS9 MK03 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25241761 27880917 11988087 27432908 28675297 32707033
DUS7 MK14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 9788880
DUS4 MK14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28675297 27432908 16189514 11387337
ATF2 FOS â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
JUN ATF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8027667 20102225 28514442 16511568 23661758 15546613 26496610 2320002 20195357 10327051 1827203 9445037 20511396 10207054 25609649 33961781
FOS ATF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 1828107 25416956 32296183 16511568 23661758 20195357 33961781 1827203 26186194 25609649 20102225
RAF1 BCL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8929532 8910675 12488548 9194558 15849194
P53 BCL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21624955 30683842 21597459 32064756 19521340 12667443 9194558 16443602 23316052
JUN BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14623928 17262823 19335069
MYC RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314511 9315742 28628118 28205554
MYC ELK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
ANDR STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12804609 11322786 16713569 11751884
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
SHC1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20935677 11773443 16713569
LCK RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7935389 8939988 16189514
SMAD3 ANDR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11707452 11280774 12226080 16713569
SMAD3 JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10903323 11306568 10220381 9732876 21829441
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
PEBP1 RAF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17097642 14654844 16189514 11853019 15886202 21831839 10757792
ANDR JUN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9211894 33640491 16713569 8798722
TRI25 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17418098 31527615 19805454
TNIP1 MK01 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12220502 16713569 26046540 21988832
PEA15 MK01 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 22213050 11702783 33961781 17255949
STA5A MK01 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 10194762 25241761 10996427
MK01 PTN5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27880917 9857190 33961781 28675297 28330616
MK01 PTN7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 27880917 12592337 10702794 10206983 10415025 28675297 12413699
MK03 PTN7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 27880917 10702794 10206983 10415025 12413699 10559944
MKNK2 MK14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25241761 10922375 12897141 33961781 26186194 20936779 23602568 32707033
DUS1 MK14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20347885 25241761 27880917 7535770 11359773 11278799 20936779 28675297 27432908 21911040
DUS16 MK14 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 27880917 11359773 14586399 11489891 33961781 26186194 20936779 28675297 27432908
MK14 KS6A4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31980649 10922375 23602568 33961781 26186194 10806207 25852190 9792677
FOS ATF2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 25609649
MK01 ATF2 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 31964530 11865055 7737129 8995385
MK01 M3K1 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 14500727 24135036 14581471 10969079
MK01 DUS2 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 27880917 8626452 28675297 27432908 16288922
MK01 RAF1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 10958680 16093354 15664191 19058874 11409918
MK03 RAF1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 11409918 9446616 19058874
MK01 FOS â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 11431474 12972619 8248197 7816602
MK03 KS6A6 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 21900206 32707033 31678930
KS6A4 MK01 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 9687510 11035004 31980649 10922375
DUS4 MK01 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 32296183 31980649 27880917 7535768 8626452 28675297 27432908
MK01 MBP â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 17255944 14530346 12114318 10958680 12944901 11983899 11258664 10464310 11570821 10978313 12760422 10371216 17906618 9596579 8846788 22778266 12588875 9792705 15380617
RAF1 MP2K2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16189514 31980649 21988832 24746704 8393135 9671314 11909642 8157000 9808624 16364241 19058874 32707033
MK03 ELK1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 20371703 25241761 16291755 16998585 15967991 14499342 12473660 15782123 8208531 29259132 34497368
DUS4 MK03 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 27432908 11387337 7535768 19843478
MK03 KS6A3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 25241761 8939914 31980649 9915826 12832467 32707033
MK03 KS6A1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 12832467 32707033 9915826 31980649
MKNK1 MK14 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11157753 28514442 10922375 9155018 33961781 20936779 26186194 23602568 32707033 23455922
MKNK2 MK01 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10922375 11013076 12897141 9155017 33961781 32707033
MK03 MK01 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 31980649 16424009 33961781 19058874 23602568 32707033 23397142 26344197
MK14 MK01 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11157753 12697810 18586681 22521293 17255949 21675959
MK01 DUS6 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9535927 31980649 27880917 15632084 26050649 9596579 18060821 25515236 12840032 28675297 27432908
MK01 DUS1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18519678 31980649 11278799 16286470 19892016 8626452 27432908 10617468
MK03 DUS1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 20347885 25241761 31980649 11278799 19892016 15677475 10617468
MK03 KS6A2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 25241761 8939914 31678930 33961781 23602568 12832467 32707033
MK03 MK14 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 21675959 12697810 11238443 23397142
MK03 DHYS â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32296183 31980649 26496610 23602568 24722188 25852190 32707033
PTPRR MK03 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9857190 10419510 27880917 10066421
MP2K2 MK03 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 7687743 9006895 8226933 8626767
MK03 PTN5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 27880917 9857190 33961781 28675297 28330616
MK14 ATF2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10581258 16998585 21444723 12110590 17170118 10708586 12697749 16945434 10085140 11839738 17380123 11279118 7535770 26987986 10978313 9596579 11566021 25098452 16456540 9162092 9753474 9235954 20213747 12118074 26391660 9207092 14499342 31964530 11259586 11532856 18695677
RAF1 MP2K1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15866172 31980649 10958680 23934108 15485920 11604401 19058874 34407391 18556463 9733801 26496610 9311917 10757792 8621729 7527398 27703006 24746704 17979178 1326789 34017080 17724343 32707033 8394352 19197339 8157000 16093354 20212043 25155755 7731720 21336309
MKNK1 MK01 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 31980649 10922375 9155017 33961781 32707033
ELK1 MK01 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11279280 11857080 12594221 8208531 10644696 12551925 34497368 15655247 16291755 15967991 14557262 8586671 20371703 21655091 8846788 15782123 9130707 12220533 8386592 12788955 11532856
PTPRR MK01 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32296183 10419510 25241761 27880917 10601328 9857190 33961781 26186194 28675297 16148006
KS6A2 MK01 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 8939914 23602568 9915826 31678930 33961781 25852190 12832467 32707033
MK03 MP2K1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10748187 9006895 8626767 9733512 19197339 8226933 19058874 34497368
PTPRR MK14 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 27880917 10601328 33961781 26186194 23932588 27432908
MK14 MAPK2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 31980649 21988832 17255097 25852190 23455922 9768359 17395714 26496610 11042204 23602568 21675959 8846784 11551945 10922375 32707033 10581204 7592979 33961781 26186194
ATF2 JUN â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
KS6A3 MK01 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 25241761 8939914 31980649 18156174 21988832 12016217 9915826 31678930 33961781 23602568 12832467 32707033
MP2K2 MK01 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 23519423 11134045 12788955 11823456 21675959
MK01 KS6A1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31980649 9430688 10922375 23519423 12594221 29997244 16039586 32814053 12618428 9915826 33961781 12832467 23455922 24623782
DUS6 MK03 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 9535927 32707033 31980649 27880917 25515236 12840032 27432908
ATF2 RAF1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
ATF2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 10366004 10327051 8530413 12052888 15068801 12751796 9502786 9141200 9252389 11238729 12903123 19255142 11736649 16511568 9819389
ATF2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 25609649 20102225 15546613 2320002 10327051 1827203 9445037 26496610 20195357 16511568 20511396 10207054 8027667 23661758 31515488 18641343 1828107
BCL2 RAF1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11463391 11463392 11532940 11704864 12566895 12667443 14764585 15516985 17446862 19289794 19565474 22039431 23064052 23377657 23430059 23850759 24027568 8929532 9069260 9872359
MYC BCL2 â—¼   DOWN_REGULATES ✅ - 17.0 1.0 ACSN 11274345 11283613 11283614 11704864 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
MYC BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8036017 17404573 12695333 24167291 18809243 19201832 16316993 19649202
ESR1 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19148464 19160418 9306964 11261829 21841772 10542244 20664923 18414489
STAT3 BCL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 12400004 15805299 20514402 15184887 17997399 18320073 20880395 17089128 20446017 20422978 18981713 21344490 19287190 19103760 20043094 16144938 20233902 21172343 18839277 14523036 10626893 19926637 21435102 22504301 11431352 21385902 22313388 16048438 22984561
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC TSC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18056446 12695333
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
STAT3 FOS â—¼   UP_REGULATES ✅ + 38.0 1.0 ACSN 10347215 11528470 12223527 13130303 14607900 14670306 15218058 15356132 15573129 15810077 16418395 16716598 16831886 17403902 18297062 18776941 18832382 19380816 19412634 20093776 20237412 20406969 20581311 21317430 21840487 21883379 22006115 22943793 22945800 23124025 23454751 23953057 24857661 27216177 28186502 7543512 7768934 9278421
STAT3 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17204573 14737107 12640143 12600988 11685114 8071311 15040450 16293640
LCK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11404481 9484840 9344858 18070987 10815799 16189514 10825200 25814554
LCK SHC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 19901323 20230923 16497976 9121430 15592455 9446569 17389395 18578522 10921922 10482988 10764799 18452278 20068231 18669648 12522270 9685404 10896916 9927207 12237775 8702728 8610109 19651622 9741627 9710204 19664994 17016520 10816433 11075717
LCK ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9500442 10571988 25386784 11145737 7539106 27748765
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
FOS RAF1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
JUN RAF1 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
PEBP1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 23331499 10757792 23416466 10490027 17706925 21831839 16189514 14654844 15886202 11585904 17097642
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
JUN FOS â—¼   PROTEIN_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
MK01 MP2K1 â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 11279118 12697810 11741894 27884160 11352917 11134045 12594221 11823456 11266467 12788955 24623782 8157000 19058874 17255949 21675959 23241949 21336309 10757792