Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GNB2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYC PTPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12747840
CCT5 ZNRD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ZNRD2 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDK5 ACTR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAF1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19197339 7014125
AKT1 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15539407 20606012
ESR2 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16549430 17261755
BCL6 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22422878 19487462
MAPK8 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306447
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
BBS10 TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS10 BBS12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS10 BBS7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 BBS10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS12 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS7 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS7 TCP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
BBS7 CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0910268107 20080638
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
BMX ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
BUD31 WDR70 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
BUD31 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
CBX1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTTNBP2 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
LNX2 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CTTNBP2 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT3 EED â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CCT3 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CCT3 STAT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24756126 1001844
CCT3 LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
CCT3 RAF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216198 12620389
CCT3 IVNS1ABP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC CCT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
STRN3 CCT4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT4 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CTTNBP2 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CCT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT5 IKBKE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCT8 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STRN3 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CTTNBP2 CCT6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT6A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STRN3 CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT7 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STRN3 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CTTNBP2 CCT8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT8 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2CA CTTNBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2CB CTTNBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 CTTNBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
SUV39H1 DCAF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
DNAJC7 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EHMT2 FZR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 22178396 15774718
STAT3 ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
PTK6 ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0805009105 18719096
ERBB2 SOCS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 VAV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 NME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
FYN FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SUV39H1 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN SUV39H2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN MAP4K1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
FYN VAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 11262396
TCP1 GBA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21098288 1014376107
MYC GEMIN4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17353931 17093053
L3MBTL2 HDAC3 â—¼   COLOCALIZATION 2.0 0.8 intact 7719892 20385135
HDAC3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22002311 18483244
TUBA1A HDAC6 â—¼   DEACETYLATION ✅ 2.0 0.8 intact 5215415 12024216
PPP2CB IGBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 27880917
STAT3 IKBKE â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22330135
LNX2 L3MBTL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
L3MBTL2 LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
POLR1C LNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
LNX2 POLR1C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
LNX2 MAP2K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PDCL LRRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
MAP3K3 MAP2K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
STAT3 MAP2K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15378007
TCP1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB2B MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBA1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB3 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2CA MAP3K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20448038
MYC VCAM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11318876 10528192
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
POLR1C NME1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PDK1 TSSK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16336268
STRN PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
STRN3 PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R2A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1328247 19114990
PTPRR STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17360477
STAT3 SOX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20132009 18447642
STRN3 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
CCT2 CCT4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
METTL14 METTL3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TUBAL3 TXNDC9 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
PPP2CA PPP4C â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
CCT3 CDC20 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT7 CDC20 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
CCT4 CCT6A â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
DCAF13 UTP18 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
CCT2 TCP1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ACTR2 ACTR3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BBS7 RFWD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BBS7 MKKS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22500027 20080638
BBS7 RIPK4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PCGF6 BMI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 12167161 24981860
MYC CBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
CBX1 WDR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
LRRK2 CDK5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 26268594
RAF1 DCAF8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16364241 34017080
DOCK5 MKS1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 RAP2C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
TBL1Y HDAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20144646 19712061
MYC TTC27 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC WDR82 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
POC1A POC1B â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
VCAM1 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
CBX1 EHMT2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
BBS7 BBS12 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 22500027 20080638
WDR83 BUD31 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
GAN CUL3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15983046 31944090 21145461
RAF1 LCK â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 8939988 16189514
MYC PCGF6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30415952 35140242 29467282
SOCS1 VAV2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 10022833 29991678
WDR5 SOX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30089852 29383478 35140242
FBXW4 TXNDC9 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CBX1 SUV39H1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
AKT1 FANCA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14499622 11855836
ESR1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21984853 31527615
LRRK2 TTC27 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31046837 29513927
CCT2 MKKS â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CCT8 CDC20 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CCT3 CCT5 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
HDAC3 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CCT6A CDC20 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CCT5 CCT7 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HDAC3 AKT1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29523594 20026773
BMI1 EED â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23238014 24457600
EHMT2 CBX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24981860 17962312 19706462 15200951 27705803
MYC HDAC3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18483244 31155734 22002311 23079660
PCGF6 WDR5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
PDK4 PDK3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 32707033
CCT5 CCT8 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CCT4 CDC20 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
CCT7 IGBP1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
HDAC1 SOX2 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CDC20 FZR1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
CCT2 CCT3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
BCL6 TRIB3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16147992 32296183
SOX2 EHMT2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
HDAC6 ERBB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
HDAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16469706 26487511 14722073 31527615 20348541
ESR1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
PEX14 PEX7 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
STK4 STRN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24255178 24366813
DDB2 TUBAL3 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
CCT2 CCT7 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CCT2 CDC20 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ARAF RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 34017080 20130576 31980649
MKS1 B9D1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32726168 27173435 26638075
PCGF6 CBX1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 24981860 27705803
MED29 CCNC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26186194 28514442 15175163
CUL3 KLHL8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 19158078 21145461 33130828 28514442
HDAC1 EHMT2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16287849 26496610 23752268 28514442 26028330
STRN ESR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15569929 31527615
ITK FYN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10636929 8810341 16713569
PCGF6 HDAC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22325352 27705803
HDAC1 VHL â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 11641274
HDAC1 WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 22689669 26186194 23752268 27705803 28514442 33022573
SOX2 HDAC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 35140242 23667531 21532573
ILK RAF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 23455922 26496610
SOCS1 ITK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10022833 29991678
STK4 MAP1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23455922 24366813 20562859
MYC WDR5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31767764 35140242 17353931 29467282 30415952 27320920
FYCO1 MAP1LC3B â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CDC20 PPP2CA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CCT2 CCT8 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
RFWD2 TRIB3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PDK1 PDK3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CCT6A TCP1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
TUBA1B TUBA1C â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PPP2R2A PPP2R2D â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
ILK AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11825911 11546794 11313365 18339839 11278835 12149249 14500673 9736715 12176337 11445557 16189514
AKT1 PDK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 34278744 27505672 27166089
AKT1 RAF1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BBS7 BBS10 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 20080638
ESR1 BTF3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18025262 31527615
ERBB2 PTK6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20700126 18719096 22973453
SOCS1 FYN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10022833 16713569 29991678
HDAC5 HDAC3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11931768 11804585 21081666 11466315 10869435 10220385
IRAK1 IRF7 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15767370 21903422
MAP1B LRRK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21159966 24754922
MED9 MED29 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 15175163 24981860 14638676
HDAC6 TUBA1A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PPP2CA PPP2R2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PSMA2 VCP â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
DCAF13 UTP18 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BMX STAT3 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
SPRTN VCP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC1 BCL6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16147992 10611298 9627120 9753732 15454082
HDAC5 BCL6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16147992 11929873
ESR1 CCNC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11867769 31527615
TYK2 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9196040 16713569 16189514
RAF1 FYN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7517401 16189514 16713569
L3MBTL2 PCGF6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MYC XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CCT6A CCT7 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
CCT6A CCT8 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
MYC PRKN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20638938 15078880 23277542
DYNC2I2 MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC TUBG2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
ACTR1B MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TNK2 AKT1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10652228 11394904 18470881
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
GAN ATG16L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20562859 30770803
MAPK6 BBS10 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BBS10 HDAC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC BLK â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC CCT5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
CUL3 HDAC1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 15467454 15688063 17312394
EED MAP1LC3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
STAT3 ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23295773 21546410
FYN TUBA1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7678277 11826099
MYC HDAC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34147029 22286234 26496610 30415952 18271930 17314511 18003922 24951594
MAPK6 HDAC11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC HDAC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
SOCS1 JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 27144517 11133764 21508344
LCK JAK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11278738 17570479 16189514
LCK RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7935389 8939988 16189514
MAPK6 TUBA1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC RAF1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 17314511 28628118 9315742
MYC PEX14 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
PDK1 XRCC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PEX14 PEX7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 15798189 10212238
RAF1 PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 502464200 8203796 16239230
RAF1 PPP2CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 502464200 8203796 16239230
STRN PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 29802198 10681496 18782753
PPP2CA STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21199877 23431053
PPP2R2A RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15664191 23331499 16239230
STAT3 PTK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12540842 20929863 19393627
VCP SPRTN â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
CCT3 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT2 CCT6A â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CCT4 CCT8 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
IGBP1 PPP4C â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CCT3 CCT4 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PPP2R2A PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20711181 8288198
PPP2CB PPP4C â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
TUBA1A TUBB2B â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CCT5 CCT6A â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
PPP2CB PPP2R2B â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CCT6A CTTNBP2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
HDAC3 HDAC5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ATF2 MAPK8 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CTTNBP2 TCP1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
PPP2R2A PPP2R2B â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
CCT2 CTTNBP2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCT3 CTTNBP2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCT5 CTTNBP2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCT8 CTTNBP2 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCT4 TCP1 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
CTTNBP2 PPP2CA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
HCFC2 WDR5 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
TUBA1B TUBB2B â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CCT4 CCT7 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT7 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT8 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
CCT3 TCP1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
BBS10 VKORC1L1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
AKT1 STK4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 19940129 17932490
BBS10 CCT6A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
PPP4C IGBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 27880917
WDR82 WDR5 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 20516061 23870121 27705803
BBS10 CCT4 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BBS10 CCT8L2 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BBS10 CCT8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
BBS10 CCT7 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TUBA1A TUBA1B â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CCT3 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
FYN YES1 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CCT7 CCT8 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
TUBA1B TUBB3 â—¼   CORRELATES + 0.94 0.94 CCLE 31978347
PPP2CA IGBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 8434208 23892082
WDR5 WDR82 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CCT2 CCT5 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
CCT3 CCT7 â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
BBS10 CCT2 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
BBS10 CCT3 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
PPP2CB PPP2R2D â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
TRIB3 AKT1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 31844113 12791994 30071535
TUBA1A TUBB3 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
PPP2CA PPP2R4 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
TUBA1B TUBB3 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
MAP2K5 MAP3K3 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
IGBP1 PPP6C â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CCT3 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT4 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT5 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT6A PPP2R2C â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT6A STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT6A STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT7 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT7 PPP2R2C â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 STRN â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2CA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2R2C â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT8 PPP2CB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
STRN TCP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCT2 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT3 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT4 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 PPP2R2C â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT5 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT6A PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT6A PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 PPP2CA â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT7 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT8 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2 STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2 STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CTTNBP2 PPP2CB â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CA TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB STRN â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2CB STRN3 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R2C TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
STRN3 TCP1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CCT2 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT3 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT6A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A TCP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT6A CCT8 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
METTL14 METTL3 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CCT4 CCT8 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT5 CCT6A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT2 CCT3 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT3 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT4 CCT5 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT7 CCT8 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT8 TCP1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R2D â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CB PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CCT2 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT2 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT5 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT3 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT4 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT7 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT5 CCT8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCT7 TCP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IGBP1 PPP2CB â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
IGBP1 PPP2CA â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CDK5 PRKN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19399218 24486837 17327227 19050041 29899409
PTPA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21159657 18039929 19216069 23109003 10026142 10995457 18042541 20452955 18559511 18588945 16680151 19405949 16227604 16406523
ACTR2 ACTR3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
ILK AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 11546794 14500673 12176337 11445557 15899889 23840605 9736715 12149249 10592173 11313365 16189514 19460343 11278835 15212693 18772455 10226025 11825911
PPP2CB AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15367694 11087733 18039929 19216069 18077353 19556239 19996169 10026142 10995457 18042541 20452955 18559511 8650155 18588945 16680151 11812651 20360384 16406523
PDK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 12176337 15743829 12682057 11445557 15899889 12149249 10833263 15718470 11278835 10226025 11087733 14500673 16341064 19897009 9368760 24012393 11825911 9512493 9736715 11313365 9868760 15364915
TRIB3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30071535 12791994
PPP2R2A AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 18039929 19216069 18077353 19556239 19996169 10026142 10995457 18042541 20452955 18559511 18588945 16680151 20360384 16406523
TNK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22322295 11394904 25678401 20333297 10652228
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
PTK6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20606012 15994200 15539407
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 51.0 1.0 Omnipath 19197339 11971957 18767875 20230923 10576742 20068231 17570479 16189514 18669648 25241761 18691976 10576741 10618391 20688159 21745501 12087097 12801936 12048182 22798428 16854453 19058874 11997508
AKT1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 79.0 1.0 Omnipath 27979972 25360797 26804165 28273460 25751140 24101154 25751139 34052254 25362852 28114269 28793266 26265440 31239271 25601544 28474680 33630828 26119935 27144834 27425596 25531778 34206989 34465890 21945154 25195862 31792377 18640976 28775168 32015438 32523092 22234184 33536280 33622361 30600590 24362629 34155345 24658687 21060948 33162394 20153295 26668327 21730131 26549256 21666719 25605730 26039999 34226698 20823509 34516278 27033705 32064037 32271880 32513743 33990468 24812269 32053631 32929029 34058200 25772246 26364602 27765911 26678338 27979971 33552953 28171658 34129887 21376238 28416665 25998128 25109332 12535517 31988076 26933062 26598551 25373897
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 22619175 19369195 19737514 19940129 17932490 23431053 11805089 24872389 23893242 17726016
AKT1 VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16551632 19335618 16027165
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
ATF2 RAF1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11274345 12738796 18039929 20506250
MAPK8 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 11279118 17081983 20506250 12958075 9162092 19255142 8654373 20028971 15105425 17626013 12788955 11566021 15550563 10777545 23331499 7535770 15068801 21071413 17875713 9317150 16393692 15304344 18988627 7737130 26538579 21444723 602896 11896587 12110590 7824938 11274345 12874243 11971971 9399639 19436832 16533805 9670022 9029150 11865055 9207092 12804775 7737129 15212693 9405416
MAPK13 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 9207191 10581204 15140942 20506250 21614932 19135240 16393692 12244047 11274345
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
HDAC3 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
ITK BMX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12573241
STAT3 CDK5 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
STAT3 CDK5 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
FYN CDK5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 24872417 19901323 9038181 10896159 18691976 20506281 29063113 20068231 16497976 19413330 14757045 12372285
CDK5 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25038288 16651438 19156541 12763138 28114390 16879821 23941877 15096606 26198700
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
ESR1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24559156 16115928 16467118 17992604 19915977 15199112 21127199 21761336 21907803 20551150 11713584 1358436 20629094 18768663 19005469 9242384 20889718 10698518 16467117
MYC ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20920219 21627565 7906953 23421821 20716114
ERRFI1 ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11003669 18046415 24189400 25640309
ERBB2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 15173068
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
LCK ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9500442 10571988 25386784 11145737 7539106 27748765
IKBKE ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23816933 20863366 19940156
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
FYCO1 MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27246247 26468287 20100911 20562859
FYCO1 MAP1LC3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 27246247 26468287 20562859
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
HDAC1 HDAC3 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC3 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC3 HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11302704 16189514 23213415 10944117
HDAC1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
PPP4C HDAC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15805470
IGBP1 PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 23892082 21988832 20092282 16085932 18782753 24484909 28330616 9647778 21454489 26496610 32296183 24145130 19156129 11371618 10441131
IKBKE IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 16625202 25225665 9786932 15210742 22787218 10893229 26712804 16127453 12702806 16380379 15367631 12692549 17706453 16199137 16914100
IRAK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15465816 10521505 12576423 11350938 14551213 10446219 12763138 9872331 11335711 9343414
IRAK1 IRF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15767370 17457343 21903422
LCK ITK â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK ITK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 21747996 28516764 19132916 23109003 20305788 23982207 15771581 19690332 28644030 15144186 9312162 12842872 17192257 23946894
STAT3 JAK3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 11418623 12517932 12244150 27774606 12093291 12759422
JAK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 10037026 23109003 11406370 12495636 16189514 12207328 10825200 12934099 18988627 30029643
LCK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11404481 9484840 9344858 18070987 10815799 16189514 10825200 25814554
LCK VAV2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11516622 12400014 17570479 12454019
MAP3K3 MAP2K5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 12912994 23331499 25241761 16861740 19903815 14743216 11073940 16189514 17985933 24975362 10593883 25861671 12813044
MAPK8 STK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27042197 20028971
MAPK8 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 23255093 17502367 21702955 19413330 11335711 9343414 23331499 15465816 12576423 11350938 20068231 12763138 9872331 18491316 18669648 10521505 18691976 20058876 15979846 14551213 10446219
MAPK8 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19651622 10551811 17081983 18767875 20068231 91332050 1651323 1748630 16713569 11243879 18669648 15210690
MAPK8 PPM1J â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20865152 18553930
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
MYC PDK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 11283613 11283614 11704864 16517405 16517406 17055429 17558397 17785433 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
MYC NME1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18628958 12695333 14519204 16440314 11960382 11983916 18414489
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
PPP2CB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16987807 16680151 15048125
PPP2CA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151 15048125
MYC NME1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11960382 17093053
PEX7 PEX14 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21554508 24865970 19208625 26344566 8991089 27597759 18359941 26086376
PPP2CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 18039929 7604263 16680151 16239230 10995457 18042541 18588945
PTK6 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18083107 17389395 21741923 19534553 7701321 19304789 16568091 15592455 12763138 15951569 20929863 18234692
WDR83 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15118098 23331499
STAT3 SOCS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18843197 14630083 16432158 20003295 20357037 10809230
TYK2 STAT3 â—¼   ENZYMATIC_REACTION ✅ 35.0 1.0 ACSN 11306493 11867689 12754507 1439146 14610620 15099563 15356132 15573129 18209571 18555777 18555778 19581928 19833085 20138012 20406969 21115385 21840487 23034983 23567181 24011634 24091328 24346288 24418198 25002027 25582338 26201938 26268945 27216177 27557510 7512720 7521688 7543512 7590867 8837607 9845545
TYK2 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29145629 21098725 12626585 10542297 23331499 15261459 8662928 30910759 23673666 14565860 12023369 30029643 14764663 18389480 23124025 25516297
DDB2 ERBB2 â—¼   KO_DOWN_REGULATES ✅ - -1.01 1.0 PKG 28854368
DDB2 OGT â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
DDB2 CDK18 â—¼   KO_UP_REGULATES ✅ + 1.16 1.16 PKG 28854368
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368