CCT3
|
IVNS1ABP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
DHX9
|
HNRNPK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
HNRNPK
|
HCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
12029088
5215418
|
PLK1
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7996327
20869364
|
KLHL20
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
VAV1
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
9705280
11804587
|
CDC42
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
11804587
|
VAV1
|
PAK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11278486
10075701
|
VIM
|
CENPU
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
VIM
|
IVNS1ABP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
VIM
|
CHD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15383276
5217202
|
ABI1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7907811
20598684
|
VAV1
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8621483
5220979
|
CRK
|
PXN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
15308668
16000375
|
CRK
|
RIN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
VAV1
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18511940
6743311
|
ABI1
|
FYN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7907811
20598684
|
FYN
|
RIN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
FYN
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11817894
15788770
|
FYN
|
NCK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219079
16966330
|
ABI1
|
RASA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7907811
20598684
|
RASA1
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6731661
15504032
|
DAPK1
|
PRKD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
ACSN
|
17703233
21172648
|
DAPK1
|
PRKD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17703233
|
NCK1
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
11817894
15788770
|
NCK1
|
RIN3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
NCK1
|
DOK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5211702
10428862
|
ABI1
|
HCK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7907811
20598684
|
HNRNPA1
|
TRA2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
CHD3
|
IVNS1ABP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TRA2B
|
IVNS1ABP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
PFN2
|
IVNS1ABP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HNRNPA1
|
HNRNPM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
810.0
|
0.81
|
STRING
|
36370105
|
HNRNPK
|
HNRNPM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
CRK
|
NCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
8879209
9837978
|
CAV2
|
NCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
12091389
|
DHX9
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
HNRNPU
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
IVNS1ABP
|
PRPSAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
RIN3
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17474147
25814554
32552912
|
PRPSAP1
|
PRPSAP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
HCK
|
RASA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16189514
7782336
|
RASA1
|
CAV2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15504032
12091389
|
HNRNPA1
|
HNRNPL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
ILF3
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22751105
12946349
31536960
23986595
22939629
|
ABI1
|
NCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
11557983
11418237
|
CAV1
|
CAV2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
898.0
|
0.89
|
STRING
|
36370105
|
SH3KBP1
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
7148030
16407834
1209329
|
CENPU
|
PLK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
19597481
21454580
33961781
21525413
32707033
|
VIM
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
HCK
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9636140
16809022
23109003
|
FYN
|
GSK3B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17607942
15676027
15652488
|
NCK1
|
RASA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21664272
10508618
16189514
9233798
|
CAV2
|
CAV1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12414992
16189514
31980649
9361015
18081315
33961781
24013648
10212252
|
PRKCA
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19836308
|
PRKCA
|
HNRNPA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
7727389
|
CHD3
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAPK7
|
ELK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10473620
|
DOK2
|
RASA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
10799545
16189514
10822173
10428862
9478921
10508618
|
DOK2
|
NCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
11689432
16189514
10428862
|
NCK1
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
PAK1
|
CDC42
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
5220560
7744004
|
PAK1
|
NCK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
11278241
10805734
8824201
11157752
10026169
10330411
10372803
33961781
9851874
11557983
15784622
|
PAK1
|
CDC42
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9535855
11157984
21029865
16678097
19596003
23455922
9705280
31871319
25150978
12879077
12606577
10360579
31478661
10684602
8107774
21048135
23175184
18057010
10802735
21167153
15548653
12650940
18426980
7744004
20936779
24276241
|
CDC42
|
PAK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
NCK1
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
10805734
11278241
10026169
23109003
11096073
10330411
8798379
11278553
16490784
11157752
15784622
9024622
9755165
8824201
|
CDC42
|
PAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
60.0
|
1.0
|
Omnipath
|
17145710
810774
10360579
21167153
8107774
10559936
9705280
12650940
16678097
23331499
21029865
10684602
18057010
15020669
21070974
11340065
21048135
15003621
20936779
10934474
11413130
15788770
15713627
9535855
23109003
11950587
19628037
7744004
12879077
12606577
24276241
10224076
19596003
8973630
19812368
11248548
10802735
18719708
10613909
10461188
23455922
|
PAK1
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
26598620
10330411
11096073
16717130
14580336
18986306
27542844
28214467
25472536
17440071
23317503
|
PAK1
|
VIM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
14722118
11895474
17081983
16565220
26369929
28390425
27457922
11420699
15713670
15766329
7983050
12458200
12761892
26956613
16964243
28096473
15345747
|
PAK1
|
PLK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
26779436
18427546
|
PLK1
|
CENPU
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
15.0
|
1.0
|
Omnipath
|
17188028
20148280
17081991
19597481
21454580
24722413
25658810
18215321
34094674
|
PLK1
|
VIM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
28390425
27603133
24196446
18056432
16260496
28953239
|
PRKCA
|
VIM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
14762106
20058876
11895474
19007248
19415658
19691289
19291697
18669648
18767875
2500966
20068231
19144319
17287340
12761892
19664995
18212344
|
CRK
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
15308668
16000375
16076871
18835194
22464172
|
PXN
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12198159
27686861
12799422
10329689
10592173
10085298
16713569
7525621
8662907
7537852
|
CRK
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
12198159
27686861
12799422
10329689
10592173
10085298
16713569
7525621
8662907
7537852
|
FYN
|
VAV1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10591186
10648627
12218089
12731048
15699036
19290918
19909365
20814939
21378271
22683124
22863785
24440149
27192565
9738502
9822663
|
VAV1
|
CDC42
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10077632
10646608
10679059
10714681
10849438
10898494
11080163
11526404
11698448
11754814
11994416
12094222
12165654
12186560
12616499
12626562
12740575
12885870
12917349
14764585
15169881
16887996
19909365
20189481
22513334
22786724
22952938
25355530
25539813
26552706
8189062
8226994
9438848
|
VAV1
|
PXN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
33.0
|
1.0
|
ACSN
|
10077632
10646608
10679059
10714681
10849438
10898494
11080163
11526404
11698448
11754814
11994416
12094222
12165654
12186560
12616499
12626562
12740575
12885870
12917349
14764585
15169881
16887996
19909365
20189481
22513334
22786724
22952938
25355530
25539813
26552706
8189062
8226994
9438848
|
FYN
|
VAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11262396
15699036
11005864
9438848
16713569
15933714
9822663
|
VAV1
|
CDC42
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
10849438
22952938
9695188
12626562
12917349
12165654
25539813
19909365
14757747
18511940
10077632
26552706
12885870
11526404
10898494
25355530
11698448
16189514
10646608
11994416
20189481
22513334
12616499
10679059
23109003
12740575
11754814
9438848
11080163
10714681
14764585
15169881
26192618
22786724
8226994
12094222
8189062
11287617
16887996
12186560
|
CDC42
|
PXN
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
19.0
|
1.0
|
ACSN
|
10934474
11248548
11340065
15001467
15003621
15020669
15169870
15882626
16329184
17517963
17785506
18719708
19741094
21178402
22126964
22821962
27248291
7761442
9831565
|
FYN
|
PXN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
7617039
10804218
16713569
23128389
|
FYN
|
SH3KBP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
17350651
23052211
23506116
16529723
|
NCK1
|
FYN
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
52.0
|
1.0
|
ACSN
|
10022831
10086337
10567412
10811803
10849428
10982827
11166270
11447289
11449354
11532940
11777939
11960372
12175651
12393695
12629515
12640133
13678960
15099563
15111329
15501236
15520864
15567848
15573129
15574420
16002046
16076871
16572188
16582911
16887996
17086423
17496910
17673906
17883421
19414323
19449109
21372296
21378271
22064427
22461508
23390297
23896411
24217602
24346288
24670066
25922287
26201938
26552706
8551221
8837607
9157999
9570538
9753319
|
FYN
|
CAV1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
9252391
29371975
11805080
12925753
21705803
12529448
11075810
15692085
14992595
8632005
10592173
16943184
12921535
16332692
12135605
20228056
15466865
33804982
24632723
33928090
18347068
34321069
|
RASA1
|
CAV2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12091389
23331499
15504032
|
KLHL20
|
DAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
20389280
25619834
|
CDC42
|
CAV1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16714282
7512369
9113980
23434736
11306516
|
PRKCA
|
PEBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
17170028
20166139
20068231
12551925
14654844
19096942
|
PRKCA
|
PRKD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
15212693
18337243
11741879
11948398
17570479
34010649
10197446
10867018
15024053
15383279
|
PRKD1
|
RIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
11784866
21209314
12829240
21357900
18669648
|
PRKCG
|
PEBP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
20068231
20166139
12551925
14654844
|