Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GSN KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTRA2 ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTRA2 CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTRA2 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAC1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 11804587
PML KLHL20 â—¼   COLOCALIZATION 2.0 0.8 intact 20389280 7900485
ID2 PRMT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 PRMT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
TSC1 PRMT6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT6 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
PRMT6 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RBX1 CORO7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21130766 8074842
RIF1 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RIF1 ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
GFAP SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOS3 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NDUFV2 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SUV39H1 SPRED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SPRED1 PRIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SPRED1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLK6 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 SUV39H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
SUV39H1 PRIM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
KLHL20 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 DCUN1D1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PIN1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TMA16 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL26 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 CRYAA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11700327 5214764
TARDBP ID2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ID2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ERG28 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PRIM2 PRIM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 15132993 9115215
PRIM1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRIM2 PRIM1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 15132993 9115215
CRMP1 NDUFV2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NDUFV2 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACTA1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 11027608
KLHL20 TSC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TSC1 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CEP126 FGFR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FGFR3 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MECP2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEP126 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
LUC7L2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT CRMP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
HTT CEP126 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
HTT KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
KLHL20 ATXN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRMP1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KLHL20 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLF11 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
NARS1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 NARS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 MECP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLK6 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12928483
GLE1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 KLF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 MECP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 MECP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MECP2 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEP126 LUC7L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
LUC7L2 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TARDBP PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 GRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 GFAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GFAP KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NOS3 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GBP2 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DBH KLK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 KLK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 F13A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL22 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 TARDBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CEP126 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TTR KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DBH KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WFS1 KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KLHL20 CCDC7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KLHL20 CUL3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 20389280 7900485
CUL3 KLHL22 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
RBX1 HSPB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30349055 25277244
TMA16 RBM12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PIN1 PML â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22033920 18039859 21840486 20100838 24586174
CUL3 UBE2M â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CUL3 IPP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
ERG28 TTR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RHOA ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
TTR CEP126 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
COPS6 RBX1 â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ARHGEF12 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 11094164
RBX1 UBE2M â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
CUL3 RBX1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 19818716 15448697 12481031 11861641 30349055 25270598 20027226 22405651 26100637 19256485 11311237 19250909 25278611 26286618 20865015 15601839 19617556 29958295 33504946 12684064 24145166
HSPB1 CRYAA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11700327 32814053 12601044 33961781
DCUN1D1 RBX1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ACTA1 GSN â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
RAC1 PAK1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 5217506 15688026
ARHGEF12 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
DCUN1D1 UBE2M â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
PAK1 RAC1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 24625804 19327867 15143066 9535855 17245428 11134022 15673687 15289329 16492808 16551621 21029865 16678097 19596003 26175416 17389360 31871319 24056087 25843002 25150978 12879077 15212766 19693014 11030651 16630611 20810653 8107774 11130076 25468898 29615491 19732720 19270716 21474670 10706722 19277120 10802735 21167153 24172987 21454543 15548653 16002993 12650940 18426980 19961560 11950930 24792722 15688026 7744004 20936779 25819133 15075243 22581261
CUL3 RBX1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
PRIM1 PRIM2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PAK1 RAC1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GSN ACTA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 8395021 10583954 10854330
RAC1 PAK1 â—¼   UP_REGULATES ✅ + 11.0 1.0 ACSN 11121431 11274345 11544274 11756498 15157156 15229651 18000759 19151919 24459205 27331412 9655398
RAC1 PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 130.0 1.0 Omnipath 17145710 15229651 21167153 8107774 24792722 16551621 14579272 10023776 8805275 18325335 11134022 19693014 19277120 21474670 12650940 15673687 19961560 20711231 11950930 16678097 12123608 19270716 9744077 9148763 11689432 23331499 21029865 16368433 11121431 16492808 15075243 21454543 10592173 24172987 15212766 7493928 10793146 21070974 10706722 8910277 17245428 25819133 20936779 11030651 9989831 15157156 9535855 19359598 25150978 16049136 18854161 19628037 15688026 12879077 7744004 11728826 16002993 9764820 9032259 25843002 10224076 19732720 19596003 10802735 19893577 16212495 11130076 12480336 11152757 19327867 22117219 22581261
RBX1 EPAS1 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 11292861 9122164 10878807 12821933 12101228 11292862 10823831 11504942 11454738 10944113 11358837 11024059
RBX1 CUL3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
RBX1 CUL3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11583996 11900249 12648680 12820959 14744430 15340381 15459660 15688063 15703371 15760909 16498403 16547521 16697054 17312394 17884153 18545270 18931676 19090789 19427028 19560419 19622404 19686080 19809470 19818716 19847258 20006983 20531300 20599425 23030059 23377657 23845861 23850759 27984721 9242610
DAPK1 PIN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 24853415 25849135 27618008 21497122 21852138 26387736 29665256 25766872 23633483
UBE2M CUL3 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 19617556 18826954 25349211 23912815 25314029 18206966 21940857 23201271 26906416 19250909 30610225 25531226
DAPK1 TSC1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11323415 17703233 18974095 19180116
KLHL20 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20389280 25619834
TSC1 RAC1 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11955434 12829230 12906785 15611338 15851026 15967165 16636147 17680028 18974095 19022819 20146692
ARHGEF12 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9789025 17145710 15364580 23405219 32203420 9113980 9641915 20300064 10592173 11373293 12515866 11094164 11149925
ECT2 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 32203420 9113980 9641915 15774750 11149925