Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RECQL4 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19567405
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PHYH C7ORF31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH ABHD17C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH CDC23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH CRLF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH EDRF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH KLHL20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH LHX6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH MAGEA11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PEX5 PEX12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12096124 5215526
PEX5 PEX14 â—¼   COLOCALIZATION 2.0 0.8 intact 19197237 7231031
PEX2 PEX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 19687296
PIAS1 PEX7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TOM1L1 PHYH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PHYH TRAF5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH RNF112 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PHYH PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATM WRN â—¼   PHOSPHORYLATION 0.8 0.8 Signor 10608806
ATM EXO1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 20019063
PEX5 PEX14 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 12096124 5215526
PEX14 PEX5 â—¼   COLOCALIZATION ✅ 0.81 0.81 mint 19197237 7231031
PDCD6IP TPI1 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
C6ORF226 PEX7 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
ATM MDC1 â—¼   PHOSPHORYLATION ✅ + 0.82 0.82 Signor 12607003
FANCM PHYH â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
XRCC4 FAM9B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25416956 32296183
POLB CAT â—¼   KO_UP_REGULATES ✅ + 0.83 0.83 PKG 28854368
PEX14 ABCD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21525035 34079125
XRCC4 PHYH â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
ATM PHYH â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
PEX14 PEX7 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
COPS3 DDB2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ATM PEX5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10567403 26344566
EXO1 PHYH â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
SETX PHYH â—¼   KO_UP_REGULATES ✅ + 0.88 0.88 PKG 28854368
PEX13 PEX5 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MDC1 ATM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29656893 26734725 12607005 14519663 18006705 28943310
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
PEX14 PEX7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 15798189 10212238
PEX7 PEX5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11865044 30375424 11546814 22002062 16189514 30378028
FAAP20 PHYH â—¼   KO_DOWN_REGULATES ✅ - -0.91 0.9 PKG 28854368
PEX12 PEX5 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
PEX10 PEX12 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
PEX10 PEX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 10837480 16189514
PEX5 PEX7 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
PEX13 PEX14 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PEX14 PEX5 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
WRN POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
WRN POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
WRN ATM â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
ATM MDC1 â—¼   PHYSICAL_INTERACTION 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
WRN ATM â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
ATM MDC1 â—¼   SHARES_COMPLEX 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   ENZYMATIC_REACTION ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM EXO1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM MDC1 â—¼   REGULATES ✅ 64.0 1.0 ACSN 11331603 11571274 11850621 11877377 12086603 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15242590 15279786 15375219 15377654 15459660 15485915 15798197 15964794 16163361 16332722 16531125 16713580 16805667 16818604 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17660363 18001824 18006705 18087292 18469862 18543256 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19282663 19342888 19622404 19686080 19772495 19793801 20051983 20160076 20723763 21376743 22743550 23030059 23847781 24050180 7575488 9407949 9488723
ATM MDC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 28193847 21705321 22234877 12607003 12607005 22234878 17525332 18006705
ATM PEX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 26344566 10567403 26967755
ATM EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 15964794 11877377 17303408 18756267 16163361 15867354 23847781 23675572 25956864 26240375 11438669 24705021 12607003 18048416 17525332 20019063 15459660
PEX7 PEX10 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21554508 24865970 19208625 26344566 8991089 27597759 18359941 26086376
PHYH PEX10 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 8858165 24865970 10022913 26138649 9653144 11546814
PEX10 PEX13 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 28521612 9539740 21980954 24865970 25016021 28611990
PEX10 PEX12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 10837480 12096124 10562279
PEX12 PHYH â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 8858165 24865970 10022913 26138649 9653144 11546814
PEX12 PEX7 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21554508 24865970 19208625 26344566 8991089 27597759 18359941 26086376
PEX12 PEX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17145710 10837480 19687296 22002062 12456682 10562279 12096124
PEX5 PEX13 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21554508 24865970 19208625 26344566 8991089 27597759 18359941 26086376
PEX2 PEX13 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 28521612 9539740 21980954 24865970 25016021 28611990
PEX14 PEX13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15798189 11865044 21525035 12096124
PHYH PEX13 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 8858165 24865970 10022913 26138649 9653144 11546814
PEX7 PEX14 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21554508 24865970 19208625 26344566 8991089 27597759 18359941 26086376
PHYH PEX14 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 8858165 24865970 10022913 26138649 9653144 11546814
PEX14 PEX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 24235149 10212238 10837480 15798189 11865044 22002062 10022913 16189514 21525035 12096124 19584060 19197237
PEX2 PEX5 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21554508 24865970 19208625 26344566 8991089 27597759 18359941 26086376
PEX7 PEX2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 21554508 24865970 19208625 26344566 8991089 27597759 18359941 26086376
PHYH PEX2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 8858165 24865970 10022913 26138649 9653144 11546814
PHYH PEX5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 26220973 9668159 25538232 26138649 11546814
WRN PHYH â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
MDC1 PHYH â—¼   KO_DOWN_REGULATES ✅ - -1.07 1.06 PKG 28854368
ERCC6 PHYH â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
RECQL4 PHYH â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
NHEJ1 PHYH â—¼   KO_DOWN_REGULATES ✅ - -1.11 1.1 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
POLB PHYH â—¼   KO_DOWN_REGULATES ✅ - -1.3 1.29 PKG 28854368
DDB2 PHYH â—¼   KO_UP_REGULATES ✅ + 1.31 1.31 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368