Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATF2 YTHDC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24269672
ATF2 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20102225 23661758
DVL2 BCL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
BCL6 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
KAT5 CCT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
YWHAB CDC25A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220486 7644510
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
CDKN2A KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16915296
DVL2 CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 17199046 12958364
COPS6 BTBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DCUN1D2 CUL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
SPOP DDIT3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NFE2L2 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22691366 14978030
DNTT PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11554927
MAPKAPK2 ELAVL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20626350 27215284
FXR1 CSNK2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 BTBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 ACLY â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 TNFAIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 TASOR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 MAGED1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 C1QBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 PKM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HNRNPDL HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PPP2R1A HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
TASOR2 HSPD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPD1 SAFB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 HSPD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
TRMT6 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GMCL1 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
KAT5 CCDC47 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
NFE2L2 KEAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 19560419 23850759
NFE2L2 KEAP1 â—¼   PROTEIN_INTERACTION 2.0 0.8 ACSN 19560419 23850759
NFE2L2 KEAP1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19560419 23850759
SAFB ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10707955
VCP UBE2D1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCUN1D2 CUL4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
C1QBP YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
DVL2 DCUN1D1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DCUN1D1 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
GABARAP DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20639871
SNRPE GEMIN5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214807 11714716
LRRK2 AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DCUN1D2 CUL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19617556 0812528106
CUL3 BTBD2 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 34591642
NFE2L2 CUL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21793854 20452971
CUL3 HSF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19768582
CUL3 TNFAIP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19782033 25416956
NFE2L2 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23637463 22547061
ESR1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 24641954 20623181
PIK3R2 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB SPTAN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8009988 20598904
DVL2 RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11779461 18162551
RHOA NCL â—¼   COLOCALIZATION 2.0 0.8 intact 21281639 8086571
KLHL12 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
AURKA DDX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
ESR1 ARHGDIA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21447808 11060289
SPTAN1 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NCL BTBD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NCL NAT10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NCL SMNDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ESR1 CTNNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16628468
HNRNPL HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001635 23976881
ELOC COMMD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17183367 5219492
POLR2C POLR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0804424105 18562274
KLHL2 KLHL12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
RPS6 RSL1D1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CUL4A DCUN1D1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HUWE1 PCNA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25147182 22203964 27146073
CAV1 RHOA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 31871319 20460433 9647788
CCT7 CDC20 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
DDIT3 SPOP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16189514 24990631
BMI1 FXR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
KAT5 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27295567 16169070
LRRK2 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
ESR1 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
CUL3 PSMD2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22466964
LRRK2 PCNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
UBXN7 CUL4A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
C1QBP ERAL1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32877691 22904065
SNX9 AP1B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
UBXN7 ELOC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22537386 18775313
UBXN7 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22466964 18775313
CDC20 AURKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22340593 10377410
AURKB NAT10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29568061 31586073
FAF1 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28443643 18775313
CUL3 BTBD9 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33130828
LRRK2 RHOA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 21454543
SPOP BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15897469 34316702
BMI1 RRP12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 NAT10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 PRDX4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 G3BP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
ESR1 AURKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21761334 31527615
ESR1 PRDX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
ESR1 NACA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
COMMD1 COMMD8 â—¼   PHYSICAL_INTERACTION 821.0 0.82 STRING 36370105
MRPL21 MRPL49 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
AMBRA1 CUL4A â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
DDIT3 ATF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23661758 20102225
FXR1 C1QBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29395067 32877691 21653829
KLHL2 KEAP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 32296183 30190310 33961781 15383316
CUL4A PWP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17079684 31973889 21145461 19295130 33355139
AURKA SNX9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
UBXN1 BTBD9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26389662 26186194
SRRM1 SPOP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29996942 31911863 28805822 21988832
ARRB2 CLTC â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HUWE1 PHAX â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CUL3 KLHL13 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
CUL3 PEF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 27716508 21145461
CUL3 ACLY â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21145461 27664236
ESR1 RRP12 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
NUP153 NUP93 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
IPO5 KPNB1 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CTNNB1 RUVBL2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
KEAP1 PALB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
TNFAIP1 UBXN1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
GPS1 COPS8 â—¼   COLOCALIZATION ✅ 0.85 0.85 mint 24421388
ESR1 PSMD1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25604459 20348541
PSMD2 VCP â—¼   PHYSICAL_INTERACTION 849.0 0.85 STRING 36370105
AP1B1 ARRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11877451 12070169 10097102
PSMD1 VCP â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
RPL9P9 VCP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
BRD4 SPOP â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28805820 34133717 34588438 28805822 31559706
GPS1 COPS6 â—¼   COLOCALIZATION ✅ 0.86 0.86 mint 24421388
ARIH1 UBE2D1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
ELOC CUL3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 21988832
LRRK2 DVL2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31046837 19625296
COPS4 CUL4A â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CUL3 GMCL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 21145461 25416956
BECN1 AMBRA1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 23974797
KLHL5 CUL3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 31652307 21988832
CUL3 KCTD3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781
CUL3 KLHL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 23838290 33961781 21145461
CUL3 ARMC5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781 33130828
CUL3 BTBD2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 19995937 17543862 21145461 19295130
KCTD10 KCTD13 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
KCTD10 TNFAIP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
UBXN7 VCP â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
BTBD2 COPS3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
COPS6 COPS3 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24421388
KLHL7 CUL3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21828050 21145461 33961781 28514442
MAP1B LRRK2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24754922 21159966
DVL2 ARRB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 16189514 11742073
COPS7B CUL4A â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
KCTD13 TNFAIP1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
COPS7A CUL4A â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SNRPE SRRM1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CUL3 KCTD10 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
NCL NPM1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
COPS3 CUL4A â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CUL3 KCTD13 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CUL3 KLHL12 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HNRNPA2B1 HNRNPL â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
COPS8 CUL4A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
HUWE1 UBE2D1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
PALB2 KEAP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 31257023 26649820 25016020 22331464 30126895 33961781 28416489 28398198
CUL3 KCTD9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 33961781 33130828 21145461 26334369
CDKN2A NPM1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
COPS6 CUL4A â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
AMBRA1 BECN1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
H2AFY SPOP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MAPKAPK2 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15629715 17292828
CUL5 ELOC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24438103 21199876 15574593 21145461 30166453 24076655 23806657 31253590 11384984 16530799 20463065 14564014 17351129 22479405 24402281 24390335 23098073 32513959 33961781 24390320
CSNK2B EIF6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ESR1 KAT5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31527615 17418098 16260778 22081016 11591700
KEAP1 CUL3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22911784 21357422 19818716 17822677 16449638 15367669 30765703 22558124 28186440 33130828 17439941 20599909 15282312 21145461 22448038 25742418 26757824 16790436 32296183 24896564 20534351 23727018 18251510 24127568 20027226 22245129 15983046 24322982 32341456 25628777 20421418 15572695 33391509 18417180 20865015 15601839 32854194 30273379 30383469 20864537 26219975
ESR1 PWP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
HSD17B10 UBE2D1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
KLHL5 GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CUL3 DCUN1D1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CUL3 KCTD13 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19782033 32296183 25416956
SPOP CUL3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22911784 21577200 21988832 19256485 28216678 29160310 25011449 30244836 16524876 22013077 22632832 33961781 25278611 19261606 31559706
CUL3 KCTD10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21145461 19782033 32296183
RHOA ARHGEF12 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 12220504 15210733 12730235
LRRK2 PRDX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31046837 21850687 24459295
CAV1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11563984 23634843 22230296 19595769
ESR1 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12138116 18414489
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
HSD17B10 FAF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANK1 SPTAN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16904324 11222639 17223356
ESR1 DDX17 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20663877 19995069 25604459 12738788 11250900 21182205 20348541
ARRB2 ARRB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24069330 17353931 33961781 17620599
KAT5 RUVBL2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CUL5 DCUN1D1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
DHX38 SNRPE â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
ARHGEF12 RHOA â—¼   GTPASE_REACTION ✅ + 0.91 0.91 Signor 11094164
CUL4A GPS1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
PSMD1 PSMD2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 22863883 33961781 28292943 22939629 26344197
CUL3 ABTB1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 21145461 25416956
RPS10 SERBP1 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
MRPL21 MRPL50 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
PPP2R1A PPP2R2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
MRPL4 MRPL50 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
MRPL49 MRPL50 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
SNRPE XAB2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
PPP2R2A PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17245430 5219546
RPS19 SERBP1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DNTT PCNA â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
EIF6 RPL35 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL13A SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPL35 SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS4X SERBP1 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
KPNB1 NUP153 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
RPS6 SERBP1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SNRPC SNRPE â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
RPL4 SERBP1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
EIF6 RPL13A â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
SEC13 SEC16A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
CUL3 GPS1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
UBXN1 VCP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
DHX38 XAB2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
TNFRSF10A TNFSF10 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MRPL21 MRPL4 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
ARRB1 CLTC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
ARHGEF12 RHOA â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
MRPL4 MRPL49 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
COPS7B COPS8 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL4 RPS10 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
RPL13A RPS10 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
RPL35 RPS10 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
COPS6 GPS1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
EIF6 RPL4 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
RPS10 RPS6 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
COPS7A COPS8 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
COPS6 COPS8 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RPS10 RPS19 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ARHGDIA RHOA â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
FAF1 VCP â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
COPS3 COPS7B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS7B GPS1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
KEAP1 NFE2L2 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
COPS4 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS4 COPS7A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS6 COPS7B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RPS10 RPS4X â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
COPS3 COPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS3 COPS7A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS4 COPS8 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS7A GPS1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS8 GPS1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS4X â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS19 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPS6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL13A RPL4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CUL3 SPOP â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL35 RPL4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL35 RPS4X â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
COPS3 GPS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 COPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS4 GPS1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS6 COPS7A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA5 PSMD1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA5 PSMD2 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL13A RPL35 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL4 RPS19 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RPL35 RPS6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
COPS3 COPS4 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
COPS4 COPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PSMD1 PSMD2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL35 RPS19 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS19 RPS4X â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPS19 RPS6 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RPL4 RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPS4X RPS6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BMI1 CDKN2A â—¼   DOWN_REGULATES ✅ - 7.0 1.0 ACSN 15640618 17936558 20818389 21383063 21678481 21685941 22796940
NPM1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16957780 20208519 15289458 16199867 16915296
BMI1 CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 21383063 9308237 21678481 17936558 22796940 20818389 11283613 15640618 19404261 21685941
CDKN2A HUWE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17145710 16915296 15989956
CLTC AP1B1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DDIT3 PPP1R15A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17652152 31226023 15601821
CTNNB1 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9843967 14695187 16510874 15829968 11080158
CUL3 KEAP1 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
VCP KEAP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
UBXN7 KEAP1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
CUL3 KEAP1 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
KEAP1 NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 104.0 1.0 Omnipath 30122040 17020408 31257023 35380342 16449638 22245129 18417180 28939422 15475350 24130096 20421418 12145307 32057361 17462537 23727018 24704364 34894983 23857982 19920073 31262713 20599909 36038548 24997453 17015834 23722832 21988832 30778200 24322982 36333711 20486933 30465941 22448038 30576774 21262351 23645672 16888629 31169361 11909699 26078718 25582950 19706542 20463144 16006525 18694732 11439354 15985429 15572695 34815381 28186440 23066931 19560419 15601839 23986495 25628777 27212020 22302998 30793592 16790436 26536456 24512214 17822677 20027226 28533375 22215675 29423025 14517290 32911434 20484052 14585973 18387606 23382044 21383067 32159343 18757741 27091842 24011591 9887101 31941496 22558124 36165926
KEAP1 CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20534351 30273379 15983046 24896564 15282312 17439941 32341456 26219975 32296183 26757824
VCP CUL3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
VCP NFE2L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
PCNA CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
CCDC22 CUL4A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
CUL4A COMMD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
UBE2D1 ELOC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
DVL2 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 7744250 21285348 10698942 9192851 9214626
CSNK2B CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12432063
UBXN7 NFE2L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
AMBRA1 BECN1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21358617 22441670 23030059 23377657 23974797
AMBRA1 BECN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20562859 23974797 20711182 20417604 21358617 25438055 23954414 20921139 24587252 17589504 25499913 33562550
AURKB CDC20 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
CUL3 NFE2L2 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 15340381 15459660 15688063 15703371 16697054 17312394 17884153 18931676 19560419 19622404 19686080 19809470 19818716 19847258 23030059 23850759
SPOP CUL3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 21988832 23331499 19256485 28216678 21577200 25011449 34599168 22911784 15897469 22013077 16524876 19261606 25278611
ARHGDIA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 10489445 20628200 11368848 17353931 9490022 9113980 25416956 20711218 16189514 15659383 14749388 11149925
ARHGEF12 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9789025 17145710 15364580 23405219 32203420 9113980 9641915 20300064 10592173 11373293 12515866 11094164 11149925
LRRK2 KPNB1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 KPNB1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 KPNB1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
NUP153 KPNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 35044719 10749866
DVL2 LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20006983 19625296
LRRK2 PRDX3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21850687 24459295
ARRB1 DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11742073 16713569
DVL2 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12958364
ESR1 CAV1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11773442 17535799 15033483 22031296 15496458
AURKA FAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12832043 18790738 28717217 27662363
DDX17 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19995069 21182205 12738788 20348541 19718048 20663877 25604459
POLR2B POLR2C â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
TNFSF10 TNFRSF10A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 9314565 9613612 14585074 19427028 15538968 9325248 10894161 11239407 16189514 12628743 10549288 20103630 10894160 9082980 9242610 9311998 15766588 9430226
HSF2 HSP90B2P â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17213196 15497507 10224043 8080921