DVL2
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7890890
20224554
|
DVL1
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20224554
10330181
|
ARAF
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18039929
|
ATF2
|
CYP11B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11196473
11014212
|
ATF2
|
PABPC4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18083832
16129666
|
CREB5
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8378084
8440710
|
HSPA8
|
CCAR2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
22365833
8293266
|
CDK2
|
MCM6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10523313
10373557
|
KPNA2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7993392
20551905
|
AHR
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15077192
10398686
|
KMT2A
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16997566
|
CDKN2A
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15232106
5217098
|
PBX1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21746878
15611658
|
AHR
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17070097
15111621
|
RAF1
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
20674547
15664191
|
MAPK3
|
PARP1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
0508606103
16627622
|
PRKACA
|
NFATC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10611249
11749379
|
PARP1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7986053
19779455
|
PSMD4
|
PSMA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
PRKACA
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PSMD2
|
PSMD4
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16990800
5219132
|
RBBP4
|
RPN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
TFRC
|
TF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20404192
0914898107
|
GMPS
|
USP7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19834552
26046769
|
VCP
|
FAF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18711132
0805371105
|
PBX1
|
VCP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17200190
|
FAF2
|
VCP
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
VCP
|
FAF2
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
XRCC6
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
FZD7
|
ADCY1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
WNT8A
|
FZD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10097073
|
ATF4
|
FUS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18471544
|
MKRN3
|
ENKD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8153045
21516116
|
GNAI3
|
ADCY1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8327893
19703466
|
CD2BP2
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15105431
5217015
|
RAP1A
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7791872
5220596
|
GSK3B
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219694
17318191
|
EEF1A1
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
WNT3A
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10428961
8666229
|
FZD2
|
DVL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23151663
19388021
|
FZD3
|
DVL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22944199
19388021
|
ENKD1
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
USP5
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
RIPK4
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1232253
23371553
|
DVL2
|
RIPK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
16273260
23371553
|
DVL2
|
RIPK4
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
16273260
23371553
|
RIPK4
|
DVL2
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
1232253
23371553
|
ENO1
|
SNX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
UBC
|
USP5
|
â—¼ DEUBIQUITINATION
|
✅
|
|
2.0
|
0.8
|
intact
|
19373254
7288828
|
UBC
|
USP5
|
â—¼ CLEAVAGE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
26235645
7851534
|
EEF1G
|
RPL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
RPL13
|
KMT2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
EEF1A1
|
MAGED2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
USHBP1
|
EXOC7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PRKACA
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
8657310
9660757
|
TNRC6A
|
PABPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
21063388
8089941
|
G3BP1
|
CAPRIN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
24981860
|
CAPRIN1
|
G3BP1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.8
|
0.8
|
mint
|
18005740
6665011
|
SND1
|
G3BP1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
7968760
20643132
|
G3BP1
|
CAPRIN1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6665011
18005740
|
GNAQ
|
AGTR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219925
17498700
|
GNA11
|
GNAQ
|
â—¼ GTPASE_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8073283
7937899
|
CRHR1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10598591
22869609
|
GNAQ
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20399743
|
GNAQ
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNAQ
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNAQ
|
PLCB3
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GSK3B
|
APC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
10698523
|
HSP90AB1
|
AIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19375531
7021854
|
AHR
|
HSP90AB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
2153080
18805402
|
GNA11
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12578375
27515033
|
GNA11
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNA11
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
GNA11
|
PLCB3
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
HSPA9
|
TRAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
HSPA5
|
WNT9B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
AHR
|
AIP
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6594475
16257957
|
WNT5B
|
FZD8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26849959
20093360
|
PLCB4
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
PLCB3
|
PLCB1
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
AGTR1
|
BASP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
28298427
20167430
|
WNT4
|
FZD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
14671310
|
TFRC
|
ADCY5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
PLCB3
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
WNT5B
|
FZD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16273260
15578921
|
WNT11
|
FZD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16273260
15578921
|
ATP5A1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
ADSL
|
GART
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
HSPA2
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
807.0
|
0.8
|
STRING
|
36370105
|
EEF1A1
|
EEF1G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
HSP90AB1
|
HSPA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
DVL1
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
DVL1
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20224554
11425858
|
DHX9
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
15723802
30585729
|
FAF2
|
HUWE1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25147182
18775313
|
RBM34
|
NOP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CUL3
|
PSMD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21145461
22466964
|
CUL3
|
SF3B3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23951410
21145461
|
EEF1A1
|
VARS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
G3BP1
|
HSPA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
KMT2A
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
825.0
|
0.82
|
STRING
|
36370105
|
GNAQ
|
PLCB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
RBM14
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11443112
16713569
|
RBM14
|
RBM39
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28302793
22939629
26344197
|
WNT4
|
WNT7B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
HSPD1
|
SF3B3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
830.0
|
0.83
|
STRING
|
36370105
|
HSP90AB1
|
UNC45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
AIP
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
834.0
|
0.83
|
STRING
|
36370105
|
CREB5
|
ATF2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
8440710
28514442
26186194
33961781
|
RIPK4
|
UBA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
32707033
26972000
|
CUL3
|
ACLY
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
21145461
27664236
|
HSP90AB1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
ACTN4
|
VCL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
AXIN1
|
APC
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
7025676
19131971
|
FUS
|
DHX9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
27460707
29884807
|
PSMD2
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
849.0
|
0.85
|
STRING
|
36370105
|
UBC
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.85
|
0.85
|
mint
|
5220924
8570649
|
CDK6
|
CDKN1B
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.85
|
0.85
|
Signor
|
16160006
|
DHX9
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
PSMA3
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
850.0
|
0.85
|
STRING
|
36370105
|
PSMD1
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
852.0
|
0.85
|
STRING
|
36370105
|
KIF5B
|
TUBB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
EEF1A1
|
RPL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
SF3B3
|
TRAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
AHR
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
858.0
|
0.85
|
STRING
|
36370105
|
DVL2
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20224554
26496610
|
PPM1G
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34079125
27880917
|
FUS
|
HNRNPR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
859.0
|
0.86
|
STRING
|
36370105
|
HSPA9
|
HSPD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
HSP90AB1
|
HSPD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
USP5
|
UBC
|
â—¼ CLEAVAGE
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
26235645
|
PSMA3
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
ARAF
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31980649
34017080
20130576
|
PPM1G
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
PPM1G
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
30585729
28330616
|
CSE1L
|
KPNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
869.0
|
0.87
|
STRING
|
36370105
|
CUL3
|
ARMC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
21145461
33961781
33130828
|
SND1
|
G3BP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
29395067
20643132
|
ACTN1
|
VCL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
HSP90AA1
|
HSPA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
G3BP1
|
PABPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
ATF2
|
CREB5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
PABPC1
|
TNRC6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
873.0
|
0.87
|
STRING
|
36370105
|
MKRN3
|
PRR35
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HuRI
|
32296183
|
TUBB
|
TUBB2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
RAF1
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
ACTN1
|
ACTN4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22863883
22939629
|
PSMD4
|
UBC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19796170
8570649
20059542
9488668
19798103
|
ACLY
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
17353931
10653665
30711629
|
AHR
|
AIP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
CAPRIN1
|
G3BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
DARS
|
KARS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
KARS
|
RARS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
CSE1L
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
882.0
|
0.88
|
STRING
|
36370105
|
SEPT11
|
SEPT9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
883.0
|
0.88
|
STRING
|
36370105
|
HSPA8
|
HSPH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
AHR
|
HSP90AA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
PSMD4
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
HSP90AA1
|
HSP90AB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
CDK6
|
CDKN2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
DVL1
|
DVL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24643799
28514442
20224554
33961781
26186194
31340145
|
PLCB1
|
GNAQ
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16754659
12193606
11753430
|
EEF1G
|
VARS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
KARS
|
MARS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
CDK6
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
AXIN1
|
APC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16199882
22682247
10228155
29045831
18786926
20128690
19131971
26496610
10811618
9734785
29713058
23277359
17510365
|
ATF2
|
RB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18638549
15618023
|
KMT2A
|
CDKN1B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16169901
19318494
19031738
|
LEF1
|
CDKN2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19340300
|
MAPK3
|
RAP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
27503831
16939974
9560161
|
PARP1
|
XRCC6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
24140708
16490787
16794079
14734561
33961781
30585729
34079125
10400681
17283121
|
PSMD1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
FZD7
|
DVL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14636582
22179044
19388021
|
KIF5B
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
RAP1A
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
7791872
16189514
9115221
10454553
8756332
7862125
9867809
9564038
|
AXIN1
|
DVL2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10829020
29659741
23892894
21245303
|
AXIN1
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25241761
17601533
21988832
10228155
24976009
30181396
20128690
12511557
17318191
16293724
23455922
28546513
17318175
19303846
18632848
19131971
16890161
26496610
23892894
23602568
22613765
18593713
29568061
21242974
22682247
19759537
11738041
22270359
24451375
9734785
32707033
21502811
17510365
10481074
16199882
26912724
23959799
29045831
22509369
29789528
19202075
12584189
|
APC2
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
9601641
10980707
|
DVL1
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10428961
16914735
20837657
|
EEF1A1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
AGTR1
|
GNAQ
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17498700
31160049
11313903
|
GSK3B
|
EEF1G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
HSP90AB1
|
NR4A1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
AHR
|
AIP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9447995
18805402
17329248
|
WNT8A
|
FZD8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23331499
28733458
10097073
|
PBX1
|
CYP17A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9390195
7913464
9028871
|
WNT3A
|
FZD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21078818
18212053
10601008
|
HSP90AA1
|
HSPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
CDK6
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
EEF1A1
|
RPL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
PARP1
|
XRCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
UBC
|
USP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
KIF5B
|
KLC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
908.0
|
0.9
|
STRING
|
36370105
|
APC
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
KIF5B
|
KLC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
HSPA4
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
HSP90AA1
|
UNC45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
913.0
|
0.91
|
STRING
|
36370105
|
RB1
|
RBBP4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
PSMD1
|
PSMD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
22863883
33961781
28292943
22939629
26344197
|
RBBP5
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
KPNB1
|
KPNA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
17596301
|
APC
|
KHDRBS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
MARS
|
RARS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
CDK2
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
HSPD1
|
TRAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
UBC
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
HSP90AA1
|
HSPA1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
934.0
|
0.93
|
STRING
|
36370105
|
CCNE2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
HSP90AA1
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
DHX9
|
PABPC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
938.0
|
0.93
|
STRING
|
36370105
|
GART
|
MTHFD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
HSP90AA1
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
942.0
|
0.94
|
STRING
|
36370105
|
KLC4
|
KLC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
22863883
30217970
26496610
|
ACTN1
|
ACTN4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
COPB1
|
COPG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
CDK2
|
CDKN1B
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.95
|
0.95
|
Signor
|
17409098
|
PSMD2
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
PSMD4
|
PSMD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
19781552
16990800
22863883
33961781
30479383
22939629
26344197
|
GMPS
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
961.0
|
0.96
|
STRING
|
36370105
|
APC
|
GSK3B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11166179
29045831
21118991
8638126
11251183
23602568
29568061
|
CCNE2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.97
|
STRING
|
36370105
|
CDKN1B
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
34591612
|
CCNE2
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15232106
9840943
28514442
24358021
9858585
26496610
14681455
25852190
9840927
33961781
26186194
23602568
23455922
|
AIP
|
AHR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16257957
9837941
9111057
7961671
16582008
10986286
11013261
12065584
9083006
|
FAF2
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
HUWE1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
TF
|
TFRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
PSMD4
|
PSMD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
17646385
30479383
25036637
24256120
16990800
22863883
33961781
24121268
22939629
26344197
|
G3BP1
|
USP10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.98
|
STRING
|
36370105
|
UBC
|
USP7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
CDK6
|
CDKN2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
RAF1
|
RAP1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
DARS
|
MARS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
KMT2A
|
RBBP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
985.0
|
0.98
|
STRING
|
36370105
|
UBC
|
USP5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
986.0
|
0.98
|
STRING
|
36370105
|
AXIN1
|
DVL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
EEF2
|
RPL13
|
â—¼ PHYSICAL_INTERACTION
|
|
|
988.0
|
0.98
|
STRING
|
36370105
|
UBA1
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
989.0
|
0.99
|
STRING
|
36370105
|
EEF2
|
RPL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
KPNA2
|
KPNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
DARS
|
RARS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
PSMD4
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
PSMD1
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RUVBL1
|
RUVBL2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RPL13
|
RPL4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
CDKN1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMA3
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD1
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
PSMD2
|
PSMD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
AXIN1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
APC
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10421629
10581160
11487578
11955436
11967263
12051714
12554650
15001769
15327768
16039586
16288291
16940750
17143292
17318175
17936032
19619488
19751508
20006983
20705860
22270359
23343194
24023259
25730849
7542250
8638126
8666229
|
APC
|
AXIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
10421629
10581160
11487578
11955436
11967263
12051714
12554650
15001769
15327768
16039586
16288291
16940750
17143292
17318175
17936032
19619488
19751508
20006983
20705860
22270359
23343194
24023259
25730849
7542250
8638126
8666229
|
PRKACA
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
11050185
11166179
15649893
11689703
|
GSK3B
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
16944320
11166179
16799642
11967263
14663202
8524413
12554650
8638126
17910481
15327768
10581160
11487578
17318175
15465828
10228155
15020233
10421629
10698523
9832503
|
AXIN1
|
APC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
16199882
20128690
19131971
11297546
9554852
22682247
10228155
26496610
23277359
10811618
9734785
|
ATF2
|
RAF1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
11274345
12738796
18039929
20506250
|
MAPK3
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
10777545
12110590
20068231
15304344
15192015
19647037
|
RB1
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1641004
11566021
|
PRKACA
|
ATF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
1661585
15105425
92095966
|
RB1
|
CDK2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
10323868
10375532
16582612
12730199
|
CDK2
|
MCM4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
MCM6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
RB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
27.0
|
1.0
|
ACSN
|
12086603
14536078
14988723
15136767
15147722
15175241
15279786
15798197
16713580
16805667
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18469862
18590585
18636226
18995830
19282663
19342888
19622404
19793801
20051983
7575488
|
CDK2
|
CDKN2A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
32.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
25002027
28536364
7575488
9618481
|
CDK2
|
MCM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
38.0
|
1.0
|
Omnipath
|
17081983
17303408
19793801
15279786
7575488
11454864
16517729
20068231
17116885
17582221
16519687
10748114
18669648
18590585
12714602
17660363
19651622
17296725
17924679
17102137
16964243
|
CDK2
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
77.0
|
1.0
|
Omnipath
|
26581405
9315635
17303408
18692063
23437375
19413330
20871633
26148348
28806746
15279786
16326706
8626527
21902831
14627988
7575488
9190208
21697511
9139732
20068231
17570479
16189514
12006580
11420722
18669648
15811853
18590585
27507850
17380128
23160093
19638577
1756735
20418918
19262748
17660363
11777937
10499802
19651622
20058876
15173007
22263797
10207050
8756624
10542199
19664994
24466208
|
CDK2
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
125.0
|
1.0
|
Omnipath
|
26416244
20519948
19631451
16326706
17409098
15557281
9658399
23029392
22733130
17570479
26496610
23576547
12700233
9388487
10585280
27282251
27175940
15619620
25241761
15735731
9218599
9192873
17254966
15996662
9724724
11940657
18285702
22492278
23409140
18615582
12093740
22721951
15647383
9380407
17418410
16189514
17053782
17698606
25852190
10679394
17602833
9660939
12188931
15122251
10831586
25818643
22028818
21424700
12529437
15011833
12042314
11250701
11223033
23455922
8978686
16780593
21439954
15302935
19648963
14504289
9736735
10198259
16782892
11565035
21423803
16492801
9311993
12417722
17671428
21187893
15355997
28601655
10809788
10393546
15212693
10323868
26450989
23602568
18850315
12482975
9399644
15890360
9632134
17254967
26186194
20810788
20197382
15475007
12800980
17997402
12972555
15980415
24336329
26701207
25605247
26987798
|
RB1
|
CDKN1B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
10207050
9447971
24876129
31543423
11416152
11032757
9190208
30711375
10499802
|
MAPK3
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
33574916
10781063
30976006
10375532
17409098
17209046
34407842
11425869
27140628
10931950
17254967
12700233
19584057
16160006
11726503
11889117
26528715
10831586
12907657
16880511
12140288
19473963
15735731
12529437
25132260
17254966
21715330
|
CDK6
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16160006
25241761
18615582
16782892
21439954
11360184
|
CCNE2
|
CDKN1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17254966
9840927
9858585
9840943
|
CDKN1B
|
CCNE2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17254966
9840927
9858585
9840943
|
CDKN2A
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
17881001
26186194
23602568
9751050
11739795
11556834
9380698
15232106
16713569
17955473
10491434
16915296
17909018
|
CDKN2A
|
HUWE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17145710
16915296
15989956
|
HSP90AA1
|
AHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9083006
9390191
7961671
8089152
|
HSP90AA1
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
25036637
19011619
16093354
8962087
18266962
8408024
23118896
22939624
24462205
16189514
17699868
20039095
16504566
20159553
17409432
16330544
15618521
|
RAF1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
MAPK3
|
POLR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
12721286
14517250
14662762
|
MAPK3
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
11287604
11481231
|
MAPK3
|
NFATC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15657420
|
MAPK3
|
CAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
17206380
25472841
12438317
15890648
|
MAPK3
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16039586
28646232
|
MAPK3
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
14654779
23331499
19541618
18691976
16407412
19933846
9446616
9922370
15664191
18988627
|
TF
|
TFRC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
11027676
21788477
9546397
6270680
16271884
29302006
14691533
12210842
20404192
16354665
6268632
|
VCP
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
33444648
11733065
28115426
15652483
10811609
29153394
|
PRKACA
|
CAD
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
37.0
|
1.0
|
Omnipath
|
19651622
17081983
1359877
18767875
17322306
18691976
4092695
19664994
20068231
18707149
23429703
11986331
17206380
14991569
19664995
18669648
33771897
|
DVL2
|
FZD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
23821037
15936275
10698942
9716412
17130287
9674432
17627283
11358862
11101902
12015986
14636582
|
FZD7
|
WNT11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
10862746
20006983
17433286
23396967
15143170
15169958
21316585
16495441
20940229
23140633
|
WNT11
|
FZD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
10862746
|
WNT3A
|
FZD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18215320
|
RB1
|
CDK6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
9.0
|
1.0
|
Reactome
|
10207050
9447971
24876129
31543423
11416152
11032757
9190208
30711375
10499802
|
CDKN2B
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
26186194
26578655
23602568
25416956
32296183
|
GSK3B
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
11152665
20537194
10385618
11124803
12969793
19757160
16732330
10486203
16039586
14536078
18167338
12459251
12615961
|
CDK6
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
43.0
|
1.0
|
Omnipath
|
10498883
9315635
17303408
11416152
15081408
16236519
19690332
16936279
11520855
16107892
19413330
15279786
16360038
9190208
14627988
7575488
24417566
8822197
10385618
9736735
9139732
7736585
19075565
29372101
18590585
27507850
22682621
20068082
9425340
25549286
18786381
17660363
15809340
27811360
10778858
9380698
|
NR4A1
|
CRH
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9496246
15063754
21824204
19321449
|
CRH
|
CRHR2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
8536644
8243338
23504413
11123370
|
CRH
|
CRHR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
8612563
8536644
19124613
7477349
11416224
9178757
7692441
9851694
20966082
11123370
9326293
10598591
18801728
|
GNAI3
|
ADCY5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
8327893
|
GNAI3
|
ADCY6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
23109003
15539636
7935349
16460834
11376933
|
PRKACA
|
CACNA1S
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
20937870
2844809
1322891
|
PRKACA
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
19007248
11971957
20166139
18767875
20230923
9001246
10576742
23331499
20068231
7935389
18669648
18691976
9922370
15664191
19651622
12801936
9091312
10862777
9710607
11997508
|
RAP1A
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
9867809
9115221
7791872
12446733
8756332
16189514
7862125
12873387
10454553
|
RAF1
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
15485920
10523633
9819434
10486249
16189514
19058874
21139044
|
DVL1
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
AXIN1
|
FZD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
AXIN1
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
AXIN1
|
WNT8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
AXIN1
|
DVL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
ACSN
|
10428961
16288291
16940750
19751508
22270359
8666229
|
AXIN1
|
DVL1
|
â—¼ SHARES_COMPLEX
|
|
|
6.0
|
1.0
|
ACSN
|
10428961
16288291
16940750
19751508
22270359
8666229
|
DVL2
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
10329628
10829020
21245303
23892894
16713569
17529994
|
GSK3B
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
102.0
|
1.0
|
Omnipath
|
20128690
16944320
11738041
20043192
12511557
11967263
16890161
22613765
14663202
23602568
8524413
24451375
19303846
12554650
8638126
22509369
18593713
16199882
21988832
23331499
19759537
10428961
9482734
22270359
19202075
17570479
16293724
15327768
10581160
17318191
11487578
22773187
26496610
16568235
17318175
19131971
15465828
26912724
25241761
24976009
21242974
22682247
10228155
23579495
12584189
23959799
15020233
10421629
10488109
11278246
9501208
18632848
10481074
10535959
10318824
9554852
17601533
9832503
21502811
9734785
23455922
|
DVL1
|
AXIN1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
12556519
11278246
10862053
10330403
10330181
10428961
9482734
10196136
11027605
18339531
|
DVL1
|
WNT8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL1
|
FZD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL1
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
DVL1
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
PRKACA
|
RAP1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
8463283
9867809
|
MCM4
|
MCM6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
MCM4
|
MCM6
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
16902406
12694531
12364596
12614612
22939629
26496610
8798650
12207017
22863883
27173435
17296731
26344197
|
MCM4
|
MCM6
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
10882098
12185086
12909626
15279786
17102137
17116885
17296725
17303408
17582221
17608804
17660363
17887956
18451105
18590585
19158510
19793801
21406556
21527023
7575488
|
ATP5A1
|
ATP5B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
ACSN
|
10838049
11410595
11744738
12110673
14701807
14757859
18953340
22841746
|
ATP5A1
|
ATP5B
|
â—¼ SHARES_COMPLEX
|
|
|
8.0
|
1.0
|
ACSN
|
10838049
11410595
11744738
12110673
14701807
14757859
18953340
22841746
|
KPNB1
|
CSE1L
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
14627704
17593948
17662023
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
KPNB1
|
CSE1L
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10089876
10811803
10898494
11030334
11148124
11262396
11274345
11402342
11406367
14627704
17593948
17662023
18287025
19836308
21709260
21983832
7650486
8068174
9374532
9973469
|
DVL2
|
WNT11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
23821037
15936275
10698942
9716412
17130287
9674432
17627283
11358862
11101902
12015986
14636582
|
DVL2
|
WNT8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL2
|
FZD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
DVL2
|
GSK3B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
DVL2
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17234765
18077588
14636582
22411803
|
USP5
|
UBC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
19285159
20622874
22878415
26235645
18482987
19373254
16007098
31663737
25970461
27848959
17550899
26876099
24681967
23314748
17980597
16564012
27066941
17692280
22428841
8841133
22216260
24424410
34648286
|
PRKACA
|
ACLY
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
19415658
17081983
10653665
17924679
18767875
18088087
18452278
18669648
15302935
|
PRKACA
|
PLCB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
28615442
9660757
10893237
|
PRKACA
|
GSK3B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
16543730
15845746
18691976
19836308
8524413
12054501
16039586
12147701
16522636
11035810
18669648
|
CAPRIN1
|
G3BP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17210633
34799561
18005740
|
GNAQ
|
PLCB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11753430
1309799
12193606
16754659
8245028
8387502
1322796
1846707
|
GSK3B
|
WNT3A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
GSK3B
|
WNT8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
GSK3B
|
FZD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11336703
17529994
18077588
17569865
|
GSK3B
|
ACLY
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17145710
20058876
10653665
17353931
2176822
|
GSK3B
|
DPYSL2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
49.0
|
1.0
|
Omnipath
|
15652488
26952865
25628530
15483118
19413330
19541473
24416616
29758318
24765134
19666111
27079722
16964243
25104922
24923837
16568235
16190365
25995380
16230462
18491316
18669648
28674493
21345331
24904280
15466863
20961402
15345747
19651622
24133216
28077789
25040932
20202117
15212693
23308041
|
AGT
|
AGTR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
12006574
21464395
10193788
10993080
16189514
15930094
9797979
16597412
17346243
|
HSPA1B
|
HSPH1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8721986
18550409
9873016
7585962
9305631
|
AIP
|
AHR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
17145710
9111057
10986286
11013261
16257957
9083006
16582008
12065584
9837941
7961671
|
HSPA1A
|
HSPH1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8721986
18550409
9873016
7585962
9305631
|
CCNE2
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
10207050
9315635
17303408
19638577
17660363
12006580
11420722
15279786
|
WNT3A
|
FZD8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22653731
20093360
22303445
|
NR4A1
|
CYP17A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20083153
20472563
15024051
|
NR4A1
|
HSD3B2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19022561
23874725
15666793
15208301
20083153
15615861
15498889
|
NR4A1
|
STAR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19022561
23183170
18599618
20083153
18596066
|
WNT4
|
FZD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
12325120
|
WNT3A
|
FZD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18215320
19910923
|
FZD2
|
WNT8A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
11448771
11029007
15459103
12205098
22000856
22653731
11357136
15084453
23256519
23791946
|