Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PCNA ENO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
PCNA ENO1 â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
CSK PTPN11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18173375 18759926
CSK PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 15574420 14665621
REEP6 FHIP1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FHIP1B RTN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FHIP1B RABAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
AGTRAP ARFIP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
SNX1 ARL6IP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
ARL6IP1 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
EGFR DNAJC13 â—¼   COLOCALIZATION 2.0 0.8 intact 21510942 8152869
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
ENO1 SNX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SNX1 F2R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 12058063
RTN3 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RTN4 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RABAC1 FXR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 PKM â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
HCCS SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC LAMP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11085504
MLX PKLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20382893 16644726
MYC SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MYC PDGFRB â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15226411 18697203
MYC TFRC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10737792
PITPNA SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PITPNB SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLIN3 SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RTN4 RTN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SNX1 SNX8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23085988 8408210
AP3D1 AP3M2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CA087 SNX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HCLS1 SNX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 SNX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MLX SNX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
STAM1 SNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VP26A STRUM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24819384
SNX1 STRUM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 20923837
LAMP1 DYN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CA087 SNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CA087 SNX2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 SNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRC61 SNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 33957083
MYC UFD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
SNX1 TM87A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SNX1 S35F2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AP3M2 AP3D1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC AP3D1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29467282 17353931
AP3M1 AP3M2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
FXR2 SNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GPX7 SNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HCLS1 SNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MLX SNX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
REEP5 RTN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
SNX32 SNX6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ETF1 HARS â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
VPS26B VPS35 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
BIN3 SNX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BIN3 SNX5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DYN3 SNX5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ACV1B SNX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11279102 16189514
F90A1 SNX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DYN3 SNX6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DYN3 SNX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DYN3 SNX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZN397 SNX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CCNL2 SNX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TMOD1 SNX1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
PGFRB EGFR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9506992 7531698 16713569
SNX1 VP26A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11102511 26344197
SNX2 EGFR â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24797263 9819414
VPS26A VPS35 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
SNX1 EGFR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9819414 8638121
VPS35 SNX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11102511 16189514 26344197
INSR PTPN11 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
SNX1 PGFRB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16189514 9819414
AP3M1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23144738 26344197 28514442 22863883
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
REEP5 REEP6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26496610 34079125
RABAC1 SNX8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
AP3D1 AP3M1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
EGFR USP8 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SNX5 SNX2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21988832 26344197
SNX1 PAR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 12058063
SNX1 RTN4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25416956 26344197
SNX2 SNX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28514442 11102511 33961781 9819414
VPS26A VPS26B â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HGS SNX1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 11110793 19874558 16713569
PDGFRB PTPN11 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PCNA UFD1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22902628 23042605 23042607
EGFR CSK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24797263 24658140 31980649 16729043 25402006
VP26A VPS29 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 16732284 26344197 22939629 26496610 17891154 26186194 11102511 24819384
UFD1 SNX1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EIF4A2 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ENO1 MYC â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 18490439 19219071 2191300
ENO1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 2191300 18490439 19219071
TK1 GDI1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC INSR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PKLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20382893 9699482 17341548
MYC SNX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
PTPN11 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8119896 6730513
PKM TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
REEP5 RABAC1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SNX1 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SNX1 VPS26B â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
SNX2 VPS26B â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
AP3D1 AP3M2 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
SNX1 SNX32 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
SNX1 VPS26A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
SNX2 VPS26A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
SNX32 SNX1 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 32296183 25416956 21516116 28514442
SNX32 SNX2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 32296183
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SNX1 VPS35 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SNX1 VPS29 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SNX1 SNX5 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
SNX6 SNX2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 32296183 26344197 11279102 22939629 21988832 22863883
PKLR PKM â—¼   CORRELATES + 0.96 0.96 CCLE 31978347
SNX1 SNX6 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SNX2 SNX6 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
ABCE1 ETF1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
SNX5 SNX1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 28514442 23085988 26344197
HGS STAM1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 9407053 32296183 26344197 22939629 24790097 20505072 19278655 29604273 29892012 13679051 24344129 12551915 16713569 20736164 28514442 16189514
VPS35 VP26A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28514442 24747528 16732284 33961781 32296183 29893854 26344197 22939629 15078903 26496610 17891154 24344282 26186194 11102511 22863883 24819384 24980502
VPS35 VPS26A â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 24152121
VPS35 VPS29 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 24152121
AP3D1 AP3M1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SNX2 VPS35 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
SNX2 VPS29 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
VPS26B VPS29 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
VPS26A VPS29 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
SNX6 SNX1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 32296183 26344197 11279102 22939629 21988832 23524952 28514442
ETF1 GSPT1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
VPS26A VPS35 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
VPS29 VPS35 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
MYC PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7597041 18358094 22911891 18809243 1280813111085504 11085504
EGFR PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 21220489 24655521 23542172 29140271 28157503 26725162 22238610 25825764 17115032 26719139 28102297 22692198 28666590 25073158 20670598 20587074 23593472 25675097
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
IGF1R CSK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 10026153
GSK3A MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 11018017 17081983 2663470 11877389 14563837 8247524 16023596 15150404
ACVR2B ACVR1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23331499 23180781 8622651 16446785 12364468 18988627
USP8 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16520378 16120644 25853104 20736164
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
ENO1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 10082554 10528225 17595061 10802057 19846662 11134351 23421821 10403782 18490439 14506152 20886042 7880838 2005901 9074493 18070418 21559732 9119380 20412594 10681589
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
PTPN11 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28065597 23331499 11779860 7642582 10082579 8895367
INSR PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8135823 9832615 7493946 9593725
LEPR PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10449753 11018044 11342028 11085989 9600917
MYC TFRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 3302722 12695333 14519204 16466700 20631077
PDGFRB PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 8622870 19690332 8041791 18083107 8538796 23331499 19534553 11684012 7530043 16189514 12721296 12522270 8959326 17287340 16094384 7688466 8226787 8119896 12531430 11266449 12681492 12614164 8183548 23397142 7691811