Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
AR RAB3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20610535 22083957
GSK3A RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22761446
RAB39A RAB10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LRRK2 NCBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DCK DDX19B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DCK GOLM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DCTN3 ACTR10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
RPS6KB1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
APPL1 RAB22A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220032 17581628
AR APPL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12621049 20610535
RAB5A APPL1 â—¼   COLOCALIZATION 2.0 0.8 intact 5220032 17581628
HSP90AA1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0908908106 19805354
HSP90AB1 AR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21730179 1105160108
AR MAPKAPK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23365759 20610535
AR DNM1L â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10454563 21724752
AR CDK5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23941877 20610535
PRPS1 ARFGAP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ARFGAP3 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PAK2 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20936779
CDC42 RPS6KB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
CDC42 KIF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
CDC42 KLC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
CDC42 RAB35 â—¼   COLOCALIZATION 2.0 0.8 intact 19289122 7012064
CDC42 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11438723
PPP2CA CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133759 0914492107
RELA CFTR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11114294
MAP3K3 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EEF1A2 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB CHUK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CHUK HSP90AB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18949366 24323043
CSE1L IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EIF2B5 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPK11 DYNC1H1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DYNC1H1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EEF1A2 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
EEF1A2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2R1A EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
EIF2B3 GOLM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RAB34 ETF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GDI2 RAB5A â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PAFAH1B1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133715 0914307107
HSP90AA1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AA1 PAFAH1B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20133715
HSP90AB1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IPO9 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10880512 5212735
TBK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRIM28 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
IKBKG MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RNF31 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24469399 21455180
MAP3K3 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17145710 14743216
LNX1 NAGK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LNX1 PAICS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TUBB MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
YWHAQ MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFDN2 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VBP1 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2R1A MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PFDN5 MAP3K3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PPP2CA MAP3K3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20448038
MAPKAPK2 MAPK11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8622669 7535770
MAPK11 MAPK14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23602568 21900206
MAPK3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16888388 16691505
MAPRE3 MAPRE1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
UBA1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PRPS1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
OTUB1 SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RIPK1 PDCD6IP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
PITPNA SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PITPNB SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2CA PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
PPP2R1A PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
RAB14 RAB39A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RABGGTB RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7991565 18532927
RIPK1 TUBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TUBB SOD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBE2V1 UBE2N â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213148 11057907
MAPK14 MAPKAPK2 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 14499342
EEF1A1P5 EEF1A2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
COPS3 HSP90AA1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
TUBB4B UBE2V1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
YWHAQ CBL â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8005785 11697890
UBE2N UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
KIF3A KIF3B â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
GDI1 RAB12 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
DCTN3 DCTN4 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
UBE2NL UBE2V1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EIF2B2 EIF2B5 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ACTR10 DYNC1I2 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CDC42 RAB1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31871319 26344197
RAB1B RAB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
RAB6B RAB6A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
LRRK2 CDK5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 26268594
CFTR USP9X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31324722 17110338
SHARPIN IKBKG â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 23032186 8410237
RAB2B RAB2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ETF1 HARS â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MAPK14 MAPKAPK2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EEF2 ETF1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DYNC1H1 UBR4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
GMPPA GMPPB â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RAB8B RAB8A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26824392
AKT1 MAPK14 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CFTR RAB5A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26618866 19398555 21455491
KIF3A DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
PGK1 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
SOX2 PAK2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SOX2 USP9X â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31605775 23667531
ACTR10 DCTN3 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
CAP1 CFL1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ADSL ATIC â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
RAB5A APPL1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5220032 17581628
APPL1 RAB5A â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 5220032 17581628
RAB8A LRRK2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26824392 32017888
TSN TSNAX â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RABGGTA RABGGTB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
ACTR10 DYNC1H1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RNF31 IKBKG â—¼   POLYUBIQUITINATION ✅ + 0.84 0.84 Signor 24469399
OTUB1 UBE2V2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
RAB31 RABGGTA â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
RAB32 RAB38 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 26186194 31552791
LRRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
CFTR UBR4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
KIF3B RAB4A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12832475
GDI1 RAB6A â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
AR SPOP â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CHUK RELA â—¼   PHOSPHORYLATION ✅ + 0.85 0.85 Signor 10521409
RAB11A RAB1B â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
RAB11A RAB5A â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
IPO9 DISC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29961565 31413325
AKT1 APPL1 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
RAB2A RAB2B â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
PFDN5 VBP1 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
IKBKG RELA â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 15489227
DNM1L GSK3B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9731200 16189514
RAB10 LRRK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31046837 26824392
RAB1B LRRK2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31046837 26824392
AKT1 AR â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AP3M1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23144738 26344197 28514442 22863883
AP3S1 AP3M1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22863883
CFTR EMD â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26618866 31324722 17110338
LNX1 UBE2N â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PRPS1 PRPS2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AR RNF14 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
AKT1 CHUK â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AP3D1 AP3M1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
RAB1B RAB8A â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
IKBKG SHARPIN â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CBL YWHAQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CHUK RELA â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
GDI1 RAB8B â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
RAB10 RAB8A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 17353931
RAB5C RAB1B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
IKBKG TANK â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
NAGK LNX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29892012 32296183 16189514 16713569
MAP1B LRRK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21159966 24754922
IKBKG TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
AR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PFDN2 VBP1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
ATG3 MAP1LC3A â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
PDCD6IP TSG101 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ARHGDIA CDC42 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
PARK2 UBE2N â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
RAB32 LRRK2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31552791 25360523
YWHAQ BRAF â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217174 15324660
BRAF YWHAQ â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
PPP2R1A CFTR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
CFTR PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
GMPPB GMPPA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 32296183 26344197 22939629 26186194 11082198 25416956 22863883 16189514
PFDN2 PFDN5 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
UBA6 UBE2Z â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
AKT1 GSK3A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
GSK3B DCTN3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B CDK5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
AR GSK3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20127713 20610535 18687691
GSK3B AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15361837 15178691 14985354
RAB10 ENOPH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ANXA7 OTUB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
APPL1 RAB5A â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
RELA AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16713569 8798655
BRAF MAPK3 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16508002 14654779 19933846
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
PAK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31871319 32296183 17353931 25416956 20696164 20936779 9822598 10320322 9535855 21311754 16204230 32707033
RAP1GDS1 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21242305 20936779
PPP2CA CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8864841 20133759 11093160
PPP2CA CHUK â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8209688 506093200 16126728
TBK1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10783893 21138416
DISC1 PAFAH1B1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17043677 17202468
LRRK2 DNM1L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24282027 22228096 22639965 23813973 29541021
DYNC1I2 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
EIF2B1 EIF2B2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10805739 21795329 9446619
EIF2B1 EIF2B3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 17353931
PPP2CA IKBKG â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 506986200 8205130 16129692
IKBKG RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15489227
MAPK3 KLC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21385839
MAPK3 MAP2K2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 10567369 19219045 8013650
MAPK3 MAP3K3 â—¼   PHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
PPP2R5D MAP3K3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 16407301 509249200 8007293
MAPK11 MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RELA MAPK14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP2CA MAPK3 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8197172
MAPKAPK2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 28506461 28920952 28920954
TBCB TBCE â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
GDI2 RAB8B â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
IKBKG RNF31 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
UBE2N UBA1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 27173435 14517261 29537486 18678647 30097011 27182664 25527291 33619271 31638574
RAB1B RAB8B â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
GDI1 RAB1B â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
UBA1 UBE2N â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
IKBKG RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
GDI2 RAB8A â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
MAP2K2 MAPK3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
GDI1 RAB8A â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
DYNC1H1 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
KIF5A KLC1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
UBE2N UBE2V1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
GDI2 RAB1B â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
SHARPIN RNF31 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 23032186 8410237
UBE2N UBE2NL â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
BRAF MAP2K2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
AP3S1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 15469849 23144738 26344197 28514442 22863883
RAB5C RAB5A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17353931 26496610 28514442 34079125
TANK TBK1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
CDC42 PAK2 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
TBK1 TANK â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 31114588 30420664 23286385 18307994 23007157 21931555 17568778 32707033 30561431 10581243 29395067 14743216 21988832 17823124 25409927 24488098 16189514 29251827 27035970 21903422
AP3D1 AP3S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3D1 AP3M1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
GMPPA GMPPB â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
KLC1 KIF5A â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 33961781 10491391 26344197 22939629 9624122 28514442
OTUB1 UBE2N â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
DYNC1H1 DYNC1I2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EFTUD1 SBDS â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
DYNC1H1 PAFAH1B1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MAPK14 MAPKAPK2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ACTR10 DCTN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MAPRE1 MAPRE3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ETF1 GSPT1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF2B2 EIF2B3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF2B2 EIF2B5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 VBP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN5 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN5 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
TSN TSNAX â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RABGGTB RAB3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18532927 7991565 8706741 12535645
AKT1 GSK3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 110.0 1.0 Omnipath 15772344 19797085 23549785 20371716 11884598 25584893 11583116 11520785 14550568 19920184 15710331 21530327 9065430 16188907 24632852 12515807 11289110 24879152 20110348 12890758 15333638 14633703 11803463 16123357 8524413 21868755 12054501 23142783 25714023 16585200 15808505 22497526 16767165 19117997 14744935 19443725 21118801 18691976 18209096 11563975 17192257 11085518 19369195 19043530 11896604 10716737 19914182 19996208 21441927 32645325 15805282 21464307 34381779 16223362 12181443 15755769 11331582 11035810 21445305 27331409 16987514 11340086 15723049 22499768 18701488 11749387 20686112 11509608 19413330 20233866 15950778 20708687 14660586 17386267 11577096 15371448 11956225 12649200 16476742 11254732 21575859 14988390 11779850 19574224 20739666 17200115
PPP2R5D GSK3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
GSK3A EIF2B5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 19651622 19007248 17081983 20166139 9468292 18691976 18088087 11500362 19664994 20068231 18452278 18707149 12133000 16097034 19413330 18669648 15302935
RPS6KB1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17053147 21233202 8250835 15905173 19339977 19720745 16286006 12713446 20647036 20832730 18423201 11108711 17052453
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
MAPK3 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16039586 28646232
MAPK14 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 26822034 17726008 21303975 18451303
PPP2R5D GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
GSK3B RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 18201972 15465828 15280197 22761446 20537194 21194439 19345186 21660967 19997086 16407239 25629551 17183360
GSK3B CAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30894654 30123351
GSK3B MAP1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 27849007 25775433 15731007 17570479 9570753 25040932
GSK3B EIF2B5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 19007248 17081983 20166139 12133000 21798082 19413330 15302935 18701453 24023715 20068231 18452278 17570479 18669648 9468292 18691976 18088087 19651622 11500362 19664994 16097034 18707149
LRRK2 RAB10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 29562525 26824392 29308544 29127255 28860483
DYNC1I2 ACTR10 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DYNC1H1 ACTR10 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
RAB6A ACTR10 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
ACTR10 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
RELA AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20186924 18031796 20649564
AR AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20589722 11278645 17896924 18687691 22740037 12621049 12063252 22970326
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
PPP2R5D AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18039929 19216069 10026142 10995457 18042541 20452955 18559511 18588945 16680151 16406523
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
TBK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21329883 21464307 21106850
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
AKT1 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 19651622 20058876 14688280 11510412 25241761 20230923 20068231 18452278 11410590 17570479 10869359 18669648
AKT1 APPL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25241761 10490823 25814554 12621049
AKT1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17470458 18349820 29861848 16210317 21601007 17570479 11404460 22155408 12621049 14555644 11156376
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20837477 20098747 17660512
AKT1 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11943559 23331499 25241761 21071413 12183455 15149849 11438723
AKT1 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 15710601 12048203 25241761 19442713 11278366 10485711 15800029 19609947 17570479 17660512 18515365 19088076 10485710
RELA AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24466341 16619263 14576180 15517885 14715080
AR PRPS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20610535
RNF14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12612084 17110431 15604093 10085091 19345326 11673464 11779876 17082327 24422631 16713569
MAPK14 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 30644418 24424504 21820033 16282370
HSP90AA1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 1525041 19805354 20048054 15861399 17974989 26342197 17353003 26196320 16713569 27903893 1540595 21157430 19706771
CDK5 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 27917404 22014572 22275373 27902483 25982277 17043241 33932081 33038264 33974920 32846021 25851605 21799006 24424504 29423094 30414425 25691442 7565807 33994848
ARHGDIA CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 24276241 20936779 11368848 17353931 9490022 9113980 10816584 17045588 16189514 10676816 11149925 21900206
MAP1LC3A ATG3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20562859 25503391 19838173 16303767 22170151
MAPK3 BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 14654779 21478863 19541618 21135229 16508002 19933846 15664191 8621729
BRAF MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 23331499 15342917 18039929 19541618 7706312 15466476 25600339 7731720 16135787 17563371 33226073 8668348 17667937 16255777
BRAF YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16713569 8668348 17353931 15324660
HSP90AA1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
CDC42 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 17145710 8107774 10559936 25416956 10320322 23331499 15020669 11340065 15003621 20936779 10934474 11413130 17353931 9535855 11950587 19628037 32296183 16204230 20696164 11248548 9822598 18719708 10613909 9823899 10461188
CDK5 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16925597 26944284 26708747 20630875
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
CHUK RELA â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
MAP3K3 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15218148 17145710 9819420 25241761 14743216 10085062 16267042 14636585 9346241
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
CHUK RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17145710 15611276 22110409 19609947 10521409 20863851 20051109 20363318 12767944 26999213 12842894 21903422 19110719 15858576 16382138 22155370 23894194 16046471 15128824 21569639 16846590 8246997 15485852 25341660 15494311 11983155 15980040 15489227 15849198 14636585 23343355
LRRK2 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
DCTN3 RAB6A â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
DCTN3 DYNC1I2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN3 DYNC1H1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN3 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
RAB6A DCTN4 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
DYNC1I2 DCTN4 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DCTN4 DYNC1LI1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
RAB6A DYNC1H1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
PAFAH1B1 DYNC1H1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11889140 11163259 27173435 12885786 19622634 26496610 36692009
RAB6A DYNC1I2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
RAB6A DYNC1LI1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
PPP2CA EEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8386634 2555220 2176079
EIF2B1 EIF2B2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2B1 EIF2B2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
GDI1 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
RAB31 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
GDI2 GAPVD1 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 Reactome 11784320 19345684 17678623 24644286 25472813 8863739 16410077 19725050 11746448 26245486 17189207 12972505 21586568
HLA-B PTPN11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
HSP90AA1 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10744744 17145710 12441346 14743216
SHARPIN IKBKG â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
RELA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RNF31 IKBKG â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
RIPK1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
IKBKG RELA â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
RIPK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10880512 21383699 21458669 14653779 10980203 17702576 9927690 16603398 16547522 16965765 10755617
TANK IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 19854139 25861989 17468758 20484576 12133833 16189514 21419663
KIF3A KIF3B â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11208056 11226259 11449277 14603322 15618519 15852005 17641202 18497258 18820483 19081070 19565474 19718039 19853559 20215540 20375059 20643644 20956384 21602792 23031257
LRRK2 RAB8A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 30209220 32227113 32017888 26824392 29357897 29308544 29482628
MAPK3 MAP2K2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11802164 15239952 21779496 11802165 15260967
MAPK11 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK14 MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
PPP2CA MAP2K2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945 20626350
MAP2K2 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 19901323 17081983 11704645 9694850 12750173 1411546 19690332 12932319 18799465 16497976 18083107 11134045 8626767 9006895 17389395 19219045 15342917 9447970 16887817 23331499 17569879 7867743 7559390 21071413 19534553 8226933 20068231 8223433 17272394 93330262 15851026 15811950 26987942 18988627 19494114 18669648 19541618 11242034 15466476 18691976 1381507 17906627 11986622 19933846 8376945 11971971 17192257 11136732 11948414 7898932 7687743 9731057 19651622 11730323 16464493 18983981 11251083 11118451 15580310 19369195 18707149 12920017 15951569 15466214 10746662 15212693
MAPK11 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK14 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 21675959 16456544 23602568 17395714 21988832 10581204 23331499 21071413 27898710 23047924 10922375 12738796 11551945 26496610 25852190 18988627 15629715 18669648 15187187 11042204 26186194 25241761 8846784 17906627 14499342 9922370 7923353 9768359 18039929 25255283 7592979 17255097 11274345 23455922
MAPK14 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15187187 21675959 18039929 12738796 23397142 11238443 11274345 12697810
MAPK14 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 12842894 15128824 15485852 10521409 15489227 15849198 15212693 12767944
PPP2CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 18588945
MAPK3 RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 15547943 20080742 14967450 12040186 15173823 12697810 11940578 16227978 12738796 16039586 9722592 17255949 15774499 15187187 19541618 19091303 19565474 17052211 11279232 9271440 18039929 18775330 10601235 12792650 11431469
MAPK3 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 72.0 1.0 Omnipath 17081983 18767875 9731215 20230923 17693683 11135364 19413330 8314790 19664995 19415658 16083285 20068231 18452278 9712920 30628717 94064639 1737801 18491316 18669648 8144611 8245003 26505358 17287340 16094384 19033656 19651622 20058876 8376365 8325880 17924679 19162178 19664994 18707149 25692552 8125092 16964243 18212344
MAPK3 MAPKAPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21675959 17242355 7592979 14499342 14967450 23583303
OTUB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22367539 21130715 24145445 21763684 35500217
RAB6A PAFAH1B1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 12447383 23783758 12401177 25233431 11483508 17827179 15483056
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11591705 12842894 17188031
PPP2CA RPS6KB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16109716 2826472 16899564 11438723 11124802 10200280
RAB8A RAB11A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 20308558 22433857 22983554 12221131 23567335 21273506
RAB4A RAB14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16522682 16154996 14617813 23519112
RAB5A RAB14 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16522682 16154996 14617813 23519112
TBK1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 12842894 17562815 15128824 15485852 10521409 15489227 15849198 14560022 19958770 12767944
RNF31 SHARPIN â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
RNF31 SHARPIN â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11280761 11460167 14660645 17301840 18264787 21133840 21232017 24699077 24958845
TANK TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16127453 17568778 27035970 25409927 23286385 18307994 24488098 21419663 21988832 21903422 15210742 14743216 16189514 19820708 21931555 10581243 23007157 17823124 17468758 17327220
UBE2N UBE2V1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 15492226 29662619 10089880 1551980 11057907 16129784 25260751 15147900 22367539 18082144 18678647 26101372 20551964 16307917 17709375 19549727 18029035 21460221 24145445 16215985 20613989 25548215