Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
USP5 DVL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DVL2 RHOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11779461 18162551
GABARAP DVL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20639871
CFL1 PLD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6173882 17853892
ACTB DYNC1LI2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
ACTB HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACTB NUDCD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
JUN ACTB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10840940 11082319
DCTN3 ACTR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
ACTR1A DYNC1LI2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
AHSA1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16696853 20618441
BTF3 TTC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HTT CASP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CASP3 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216271 12657644
HTT CASP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16777606 10770929
CASP3 PPP3CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11478781 16189514
CASP3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9500443
YWHAE CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
SYK CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220991 8621719
LYN CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220991 8621719
HTT CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CD4 SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CD4 LCK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 8520027 9850860
PPP2CA CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133759 0914492107
VAV1 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621483 5220979
CRK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CUL3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DBNL HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PGAM1 DCTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MAPRE3 DCTN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
DCTN4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP3CA DNM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8052858 20496096
DPYSL5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPA5 DPYSL5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PPP2R1A EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
RAD23A EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16712842 5218673
HTT EEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EIF1AD RPS9 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RPS9 FKBP1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PAK2 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
SNCA FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
HTT GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GART IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HAUS7 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AB1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90AB1 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HYPK HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MATR3 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TUBB6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNW1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RAD23A HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STRAP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA HTT â—¼   COLOCALIZATION 2.0 0.8 intact 22119730 8292239
TUBB IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL23 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10880512 5212735
KIF5B IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYH9 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RELA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17310108 10646503
RHOA KIF5A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
KIF5B YWHAQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
RHOA KLC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10913441 11689693
LRRK2 LATS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ZAP70 LCK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211965 10556826
LCK SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11078745 12096713
LRRK2 ZAP70 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
SNCA LYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LYN PAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
LYN PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15644415 8034732
MYH9 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10639334 10047984
PRPS1 OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RHOA OTUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20553488 7717051
OTUB1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
VAV1 PAK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
VAV1 PAK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PAK1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
VAV1 PAK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9705280 11804587
VAV1 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11278486 10075701
PITPNA SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP6R1 PPP6C â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208117 16769727
PRPSAP1 PRPS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RHOA VAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18511940 6743311
RPL23 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 TUBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RPL23 TTC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SNW1 SH3GLB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TPPP SNCA â—¼   COLOCALIZATION 2.0 0.8 intact 17027006 5219202
VAV1 SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8986718 16546099
UBE2K TRIM31 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ZAP70 TUBB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8530437
CRK PFN1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
DENR PSMD9 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ENO1 ENO3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
NEDD8-MDP1 UBE2NL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ACTR1A DCTN3 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
RABEP1 RABGEF1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
UBE2D2 ZAP70 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
ADSL GART â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
DCTN1 DCTN4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ARPP19 SZRD1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SYK PLCG1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 8657103
YWHAQ CBL â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8005785 11697890
NAA10 NACA â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
IRGQ MAP1LC3B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HuRI 32296183
DCTN3 DCTN4 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
HYPK NAA10 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
ABCF2 GNL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MATR3 BTF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33644029 26344197
PPIA DNM1L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29128334
LRRK2 RHOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21454543 31046837
KIF5A KIF5B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DBNL PPIA â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
LRRK2 YWHAE â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ACTR1A DCTN4 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PPP2CA PPP2R1A â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
DCTN2 DYNC1LI2 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
EIF4H SZRD1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
RNF43 DVL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25891077 32103169 25825523 32965059
SPC24 PLD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MYH9 ACTB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22366308 26496610 16186248
DCTN1 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
DCTN2 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
HAUS8 HAUS1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 24981860
HAUS7 HAUS8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24981860
NTAN1 RIPK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MAP3K7 RIPK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
ABCF2 SNW1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CUL3 PEF1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27716508 21145461
ZAP70 FYN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 7760813 16189514 16713569
SNW1 SFPQ â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12840015 20467437
BTF3 RPL23 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ATG3 GABARAPL2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
OTUB1 UBE2V2 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EIF5A PFN1 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
NAA50 NAA10 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 16507339 19480662
ACTR1A DCTN3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HYPK NAA50 â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PFDN1 PFDN6 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
TUBA4A TUBB â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
PFDN6 VBP1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
LRRK2 DVL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31046837 19625296
NUBP2 RHOA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 31980649
PFDN4 VBP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HuRI 32296183
RANBP1 UBE2L3 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ACTB ACTR1A â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
ACTB DCTN2 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
DCTN1 MAPRE3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HBS1L RPL23 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HBS1L RPS9 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
CUL3 UBE2M â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
DENR RPS9 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
NAA10 NAA50 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
DDX23 SNW1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
IKBKG RELA â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 15489227
VAV1 ZAP70 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
ZAP70 CRK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10419455 16189514 16339550 16713569
SNX6 DISC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17043677 31413325 90000000
PPP5C HSP90AB1 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 27880917
ZAP70 PLCG1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 7629168 8906806 16467851
PRPS1 PRPS2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CBL VAV1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CBL UBE2L3 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
ACTB CFL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
CBL YWHAQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SGTA TFRC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
SNW1 DDX23 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 34079125 12840015 20467437
HAUS1 HAUS7 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
NACA JUN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25609649 9488446
NFKB1 SFPQ â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14743216 22536447
CBL PLCG1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
LCK ZAP70 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
OTUB1 UBE2D2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
PPP2CA PPP2R2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PFDN2 VBP1 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
CBL LCK â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
GART PAICS â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
ZAP70 DBNL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14557276 16189514
MATR3 DISC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29961565 17043677 31413325 90000000
PIN1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29225075 11432833 16713569
UBE2D2 OTUB1 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8379996 22124327
UBA6 UBE2D2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
UBA6 UBE2Z â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CBL LYN â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
DCTN1 DCTN3 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
HAUS1 HAUS8 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
UBE2D2 UBE2K â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ARHGDIA UBE2R2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ZAP70 CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10074432 29053960 10078535 11353765 11133830 9407100 8798643 10779765 9988730 22266821 16503409
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CBL PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
PPP2CA CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8864841 20133759 11093160
PDXP CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15580268
CRK TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16581250 10777559 12640026
DCTN4 DCTN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 28718761 26638075 28514442 34079125
DCTN1 PFDN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DCTN4 DCTN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 28718761 26186194 28514442 22863883
LRRK2 DNM1L â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24282027 22228096 22639965 23813973 29541021
EIF5A DOHH â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 3.0 0.9 Reactome 17213197 16533814 14622290
EEF2 DPH5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15485916 3346227 1508200
YWHAE GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SNCA GAPDH â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP2CA IKBKG â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 506986200 8205130 16129692
IKBKG RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15489227
PIN1 KIF5A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LCK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7682059 17570479 1500851
LYN VAV1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 9209406 8677749 7539782
PPP5C MAP3K7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP6C MAP3K7 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 608155200 17079228 8204431
PPP2CA MAP3K7 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 608155200 17079228 8204431
UBE2N MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17965022 17079228 10702308
PDCD5 NUDT3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TSC22D1 OTUB1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPM1A PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18586681
RHOA PFN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22820501 22479341 27228149
RELA PIN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19458071 19668231 16950761
PLCG1 SYK â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 7517665 8657103 15161916
PPP2CA SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21562258
ATG3 MAP1LC3B â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
UBE2L3 UBE2V2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ACTR1A DCTN1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
LCMT1 PPP2CA â—¼   METHYLATION ✅ + 0.9 0.9 Signor 18394995
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
PFDN2 PFDN6 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
CAP2 CFL1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
KMT2D RBBP5 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
DHPS EIF5A â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
HYPK NAA10 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
DCTN2 DCTN3 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
HSP90AB1 PPP5C â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
IKBKG RIPK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
SYK VAV1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 11331248
PPIA PPP3CA â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
EEF2 TPT1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
DHPS EIF5A â—¼   POST_TRANSLATIONAL_MODIFICATION ✅ + 0.93 0.93 Signor 32142284
PLCG1 SYK â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
PRPS1 PRPSAP1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
ACTB RUVBL1 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ACTB PFN1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
HSPA5 TPPP â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RHOA TUBA4A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TPPP TUBA4A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
KIF5A KLC1 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
PPP2R1A PPP2R2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
PRPS2 PRPSAP1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
KIF5B KLC1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
CBL SYK â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
PAK1 PAK2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 23455922 32707033 31980649
DCTN1 DCTN3 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
GAPDH TPPP â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
UBE2N UBE2NL â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
ATG3 GABARAP â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
NACA BTF3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24981860 26344197 21203952 30948508 33644029 10982809
DCTN1 DCTN4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
AHSA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
NAA10 NAA50 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
PPP6C PPP6R1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
FYN CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9677430 8621719 12244174 7782294 10629042 119942 7642581 15556646 12231245 9311917 9535867 8626543 10799548 16713569 16503409 10092522 8900205 8995358 25814554 9890970 15190072 15208330 12941616 10829062 11239464 8662998 17094785
PLCG1 CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9234717 12941616 25241761 16467851 12061819 9712732 16713569 16503409 17372230 12803489
SYK VAV1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
ACTR1A DCTN4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CD4 LCK â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RNF25 UBE2D2 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CBL UBE2D2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
LCMT1 PPP2CA â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
KLC1 KIF5A â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 33961781 10491391 26344197 22939629 9624122 28514442
OTUB1 UBE2N â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CBL ZAP70 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
SNCA TPPP â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
DCTN1 DCTN2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CNOT4 UBE2D2 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
BTF3 NACA â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
EEF2 RPS9 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
ARHGDIA RHOA â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EEF2 RPL23 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
DCTN2 DCTN4 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RABEP1 RABGEF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ACTR1A DCTN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CBL CRK â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 PFDN6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 VBP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 PFDN4 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN1 PFDN2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL23 RPS9 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PFDN2 VBP1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN6 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PFDN2 PFDN4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
UBE2N UBE2V2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PFDN4 PFDN6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PFDN6 VBP1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
DVL2 PFN1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18798527 19523939 17373907 17021034
DVL2 LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20006983 19625296
FYN PLD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9837959 16713569 15282299 12697812
GRK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 10852916 11813001 10617630
ACTB RHOA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 12805219 18001770 12732141 12429848 18923426
PFN1 ACTB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17541406 8413665 563468 10600384 10411937 10592173 19000816 16189514 19338310 9463375
ACTB CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 8913641 25416956 15364581 10592173 19704022 16189514 31515488 32296183 16713569 29892012 10980704
DYNC1LI2 ACTR1A â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
PAK1 ARHGDIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18768928 20028975 15225553 29121646 24820414 29873699 32003021
ARHGDIA RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 23.0 1.0 Omnipath 10489445 20628200 11368848 17353931 9490022 9113980 25416956 20711218 16189514 15659383 14749388 11149925
ATG3 MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20562859 11825910 17145710 16303767 11100732 11265251 17227760
ATG3 GABARAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11825910 17145710 16303767 20562859
ATG3 GABARAPL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20562859 17145710 17353931 16303767
CASP3 PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9712143 9171063 11070003 9786869 16204230
CRK CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CRK CBL â—¼   SHARES_COMPLEX 9.0 1.0 ACSN 11353765 15169881 15308668 16000375 16076871 18835194 19454690 20189481 22464172
CBL VAV1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11353765 15169881 18835194 20189481
CBL ZAP70 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11353765 15169881 18835194 20189481
SYK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 72.0 1.0 Omnipath 16289966 15922744 9525940 19419964 11133830 33512474 18273061 10829062 10799548 10540342 10934191 7721825 12435267 11331248 12604776 9890970 11042121 10092522 11997497 12522270 9857068 9988765 15556646 11742985 15536084 8621719 9102067 22880054 10551821 11239464 10617633 11994282 10570266 12881521 9535867 15577829
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
VAV1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19635790 20940296 16289966 23331499 16356860 11133830 23180781 11331248 12881521 18835194 9200440 16713569 11313921
CRK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 8683103 16289966 8626543 8621483 9617486 16713569 9416834 8524328 10962563 8626404 9367879 8662998 12393469 11792427 15581361 9013636 15581362 9178909 9988765 18835194 8943292 20697350 9129019 19380743 25814554 9461587
LCK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 9525940 10829062 10799548 10934191 7721825 16107303 12604776 9890970 17570479 11904433 9178909 10092522 11997497 12522270 8621719 9102067 11239464 11994282 11741956
CBL ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 11133830 10779765 10358158 16503409 8798643 20189481 22266821 23109003 18835194 10074432 10078535 15268851 15169881 26192618 9407100 9988730 11353765
CBL PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 7517397 9712732 12941616 25241761 12061819 23109003 9234717 16503409 11709089 16713569 17372230 16467851 12803489
CBL LYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 12149655 18235045 12244174 8627181 8621719 7782294 15304502 9160881 15190072 7721825
LCK CD4 â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 VAV1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 ZAP70 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
CD4 LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 16888650 8104794 11854499 8246987 3262426 12601806 17653867 23109003 12007789 16189514 17005671 15489916 15047060
CRK VAV1 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 15308668 16000375 16076871 18835194 22464172
UBE2M CUL3 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 19617556 18826954 25349211 23912815 25314029 18206966 21940857 23201271 26906416 19250909 30610225 25531226
ZAP70 DBNL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 14557276 16189514
DYNC1LI2 DCTN1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DYNC1LI2 DCTN2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DYNC1LI2 DCTN3 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DYNC1LI2 DCTN4 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
DHPS EIF5A â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 7673224 16452303 14622290 9188485
DHPS EIF5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 32142284 25416956 12788913 16189514 32296183 12562768 7929297 10229683
PPP3CA DNM1L â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18838687 17721437
PPP2CA EEF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8386634 2555220 2176079
SYK FYN â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10358164 11907067 12524384 14568985 15536084 17101731 19909365 20150200015 21149606 21378271 21910624 23609447 8189062 8226994 9000133 9295024 9314552 9396765 9632805 9763615
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
FYN VAV1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10591186 10648627 12218089 12731048 15699036 19290918 19909365 20814939 21378271 22683124 22863785 24440149 27192565 9738502 9822663
FYN SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 7797565 7513017 17570479 10477689 9535867 16713569
FYN SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 12893833 11162638 11744621 28671665 17570479 16713569 24860424 11078745 12096713
FYN VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11262396 15699036 11005864 9438848 16713569 15933714 9822663
FYN ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 7760813 16713569 16839418
FYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8395016 10586033 7682059 16713569
GDI1 YWHAE â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
GDI2 YWHAE â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 Reactome 20154091 18354496 21458671 27246931 17562788 20937701 22065758 22762500 22072793 23684622 21330364 16950109 20159556 20404108 21706022 21951725 27329675 19729655
HTT PAK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19240112
NFKB1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RELA IKBKG â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 9315679 9914500 9721103 10593898 9135156
RIPK1 IKBKG â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
MAP3K7 IKBKG â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
IKBKG RELA â—¼   ENZYMATIC_REACTION ✅ 38.0 1.0 ACSN 11280761 11438547 11460167 12133805 12811837 14660645 15145317 15199157 15485931 15536066 15573129 16818229 16970925 17237376 17254973 17301840 17363905 17485448 17693255 18264787 18716620 19833085 20138012 20300203 21133840 21217011 21232017 21807870 22435554 23086447 23422957 23430059 24378531 24699077 24766893 24958845 2649237 28462531
RIPK1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10880512 21383699 21458669 14653779 10980203 17702576 9927690 16603398 16547522 16965765 10755617
NFKB1 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
MAP3K7 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 24911653 11477091 17301840 18180283 19909372 15125833 24699077 17363905 16356855 18641653 24403530 18079694 18223652 14514672 17496917 19531477 20300203 11325957 21133840 21232017 18264787 9744859 10391247 16799562 15836773 10702308 23109003 12620219 14633987 17363973 19161412 22941947 23681101 17047224 29145629 11280761 16301747 15082531 26192618 14660645 20038579 24958845 15327770 20164171 11460167 16603398 21041997
IKBKG NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14743216
RELA JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18174238 9468519 16713569 10488148
PIN1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16713569 11432833
PAK2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21177766
LCK ZAP70 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK VAV1 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10398592 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
SYK LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 8798764 19664994 15536084 8621719 8798676 16497976 25990959 7518561 8845015 16189514 7539035 15659558
LCK ZAP70 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 23874979 7961936 17579062 29073235 30992398 15292262 23933134 31932281 21829558 15592455 21917715 9199177 8798643 7612267 16339550 23331499 10202147 22238573 16189514 32184287 21103055 7642520 33531381 12648457 12522270 17998387 9685404 20945976 16839418 15144186 16461343 16094384 11270871 17192257 10037717 8756661 19606965 23758320 27869819 16111633 25137454 15268851 17942891 33482200 11514606 11514605 15659558 10556826 10318843
LCK VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 20028078 24332539 898671 16285729 15708849 17050525 15699036 17570479 11005864 10669745 10636924
LRRK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20127702 22924508 22658533 24907399 19576176
LYN SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 9820500 24129562 10022120 18818202 21469132 24607955 18083107 17389395 19285079 11536198 10592173 25045209 7797565 11380624 9857068 7513017 30923129 8621719 10477689 7831290 15701717 27258042 19369195 28082678 8666899 9535867 8657103 14871838
LYN SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 11162638 11078745 11744621 12096713
LYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 17389395 12601080 8395016 16038803 10586033 1689310 20068231 1708307 7682059 8885868 15144186 16497976 8657103 15592455 16126727 17016520 16153436
RIPK1 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
PPP2CA MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18299321 17079228
PPP6C MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 17079228
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
OTUB1 UBE2N â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 22367539 21130715 24145445 21763684 35500217
PLCG1 PAK1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
PPM1F PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20016286 11864573
PPP2CA PAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9873003 18586681 10322434
PAK1 PGAM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 12189148
PLCG1 PAK2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19124833 9989831 15548136 19574218
VAV1 PLCG1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11007481 8986718 10395673 9099726
VAV1 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
ZAP70 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
SYK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 17081983 19690332 8627166 16497976 15592455 16126727 17389395 19534553 1689310 20068231 10592173 16153436 16038803 1708307 7682059 15144186 9697839 7831290 7744830 12601080 8885868 8657103 17016520
VAV1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 11340169 10849438 22952938 9099726 12626562 12917349 12165654 16713569 25539813 8673706 19909365 7518558 10077632 11278486 26552706 10395673 12885870 12573241 8629002 11526404 10898494 25355530 17050525 10592173 11698448 10646608 11094073 11994416 20189481 12670394 9550384 12616499 22513334 10679059 23109003 9891995 11007481 12740575 17540168 11804587 8630736 17054426 11754814 8986718 9438848 11080163 29145629 12941616 10714681 14764585 15169881 26192618 22786724 8226994 15010370 12094222 8189062 16887996 11709089 16467851 24243840 12186560
RHOA PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 12071848
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11591705 12842894 17188031
RABEP1 RABGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17450153 26430212 24957337 12505986 9323142 17341663 11452015 10720461
VAV1 RHOA â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
VAV1 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 10849438 22952938 9695188 12626562 12917349 12165654 25539813 19909365 14757747 18511940 10077632 26552706 12885870 11526404 10898494 25355530 10592173 11698448 10646608 11994416 16397238 20189481 22513334 12616499 10679059 23109003 12740575 11754814 9438848 11080163 10714681 32203420 9601639 14764585 15169881 22786724 12094222 26192618 8189062 8226994 16887996 12186560
TPPP SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17027006 27671864
SYK SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 12893833 11162638 11744621 11078745 12096713
VAV1 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 8900182 7518558 23331499 12573241 8629002 23180781 11331248 11262396 10592173 16189514 10092764 8630736 8986718 29145629 9151714 16546099 8809042 24243840
SYK TUBA4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9490415 8617742
VAV1 TLN1 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10077632 10646608 10679059 10714681 10849438 10898494 11080163 11526404 11698448 11754814 11994416 12094222 12165654 12186560 12616499 12626562 12740575 12885870 12917349 14764585 15169881 16887996 19909365 20189481 22513334 22786724 22952938 25355530 25539813 26552706 8189062 8226994 9438848
ZAP70 VAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10395678 23109003 14757747 15751964 7798261 16189514 11859198 23758320 16339550
YWHAE YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 20936779 20618440 17085597 21827211 12426317 15071501 12657644 17979178