Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
TP53 GSK3B â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5216887 14744935
DENND2B HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ACTBL2 LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CFL1 ACTC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ACTC1 DBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ACTC1 PLEC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CFL1 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
DSTN ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CFL2 ACTG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
STUB1 ACTR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CTTN ACTR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12176742
LRRK2 AHDC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ANXA2 AHNAK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
AHNAK LRRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FYN AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSP90AA1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12799359 11988487
PPP1CA AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8288823 20186153
NCOA3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 20305690
PPP1CA AKT1 â—¼   COLOCALIZATION 2.0 0.8 intact 8288823 20186153
PPP1CA AKT1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288823 20186153
AKT1 FLNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15461588 17570479
TP53 ANTXR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11711532
SPTAN1 APOB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ARPC3 ARPC1B â—¼   PROXIMITY 2.0 0.8 intact 20404198 0911668107
ARRB1 GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23353685
MYH9 ATG9A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21169990 8141833
PLEC BECN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22081109 8303868
BECN1 RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LYN CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5220991 8621719
FYN CBL â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
CBL FYN â—¼   PHOSPHORYLATION ✅ 0.8 0.8 mint 5217342 15556646
UBASH3B CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15159412
PPP2CA CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133759 0914492107
CFL2 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
UBC COPS5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7229502 19214193
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
TP53 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 10823891 5212595
CREBBP FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10973497
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
HDAC6 CTTN â—¼   COLOCALIZATION 2.0 0.8 intact 8295686 21847094
FYN DAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PRKD2 DST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
SH3KBP1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11894095
EPHA3 FYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 9632142
EPS15 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FLNA FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
NCL FOXO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
USP7 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17522590
HDAC6 FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PPP1R12A FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
FYN STUB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLEC HIP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPL HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001635 23976881
HNRNPA3 HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPK HNRNPA2B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HNRNPA2B1 HNRNPC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 HNRNPC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18296503 21317560
TP53 HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8200620 21821029
SRRT HNRNPK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
NUDCD2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133715 0914307107
TP53 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17184779 5219502
S100B IQGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12377780
LRRK2 TCEA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
LYN MARK4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SAFB2 MAP1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 MAP1B â—¼   COLOCALIZATION 2.0 0.8 intact 18656471 6700545
TRPM6 MYH9 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18675813 6699364
MYH9 PRKD2 â—¼   COLOCALIZATION 2.0 0.8 intact 22909819 8413258
PLEC NCAPD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SPTAN1 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22103682 8291914
NCL PPP1CB â—¼   COLOCALIZATION 2.0 0.8 intact 12185196 8262810
TP53 NDN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10713459 10347180
PDLIM7 PRKD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 PDLIM7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22266808 15829976
PLEC PEX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 PPP1CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PPP1CA S100B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ROCK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19306866
S100B RAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAQ RAI14 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TP53 ROCK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21221513 17344417
S100A4 S100A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
S100P S100A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
S100B S100A1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
S100B S100A4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
S100B S100A6 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TP53 S100A6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20591429 31837246
TP53 SAFB â—¼   COLOCALIZATION 2.0 0.8 intact 21130767 8071997
TP53 STUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21478269 17666403
TMOD1 TPM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10871039 8002995
USP7 TP53 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 5215220 11923872
UBC UBASH3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17599067 5220070
HNRNPH2 HNRNPL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CPSF4 SAFB2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
SAP18 SRRT â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
RNF113A SF3A1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
S100A1 S100A3 â—¼   PHYSICAL_INTERACTION 0.8 0.8 HuRI 32296183
HNRNPH2 RBM14 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ACTR3 ARPC3 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PNN SRRT â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
TP53 MME â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
CHERP HNRNPL â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CPSF4 SF3A1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
EP300 FOXO1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HSP90AB1 LRRK2 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
HNRNPK SAP18 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
PPP1CA TPRN â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
HNRNPK SF3A1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CHERP SFPQ â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ARPC1B ARPC4 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
YWHAQ CBL â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 8005785 11697890
SAFB2 SF3A1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPC HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CHERP RBM14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPL PNN â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN RBM14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN SFPQ â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
DOT1L UBC â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
LRRK2 STUB1 â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
SAFB SRRT â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA3 SF3A1 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA3 HNRNPK â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN SAFB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPK RBM14 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
CREBBP FOXO1 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
ACTR2 ACTR3 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SF3A1 SRRT â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPC SAFB2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPA2B1 HNRNPC â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
PNN SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
SAFB2 SAP18 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
HNRNPK SAFB â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
RBM14 SAFB2 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
TMOD3 SVIL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AKT1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
EGFR APOB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24189400 28065597
LRRK2 ARPC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20876399 31046837
TMOD3 COBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HTRA4 CPSF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CTBP1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15834423 21102443 16122695 35016035
EGFR LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24797263 31980649
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
TMOD3 INF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 PLEC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20876399 31046837
MYL6B RAC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 31871319
TMOD3 TWF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TPM2 TPM3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
HNRNPA3 SAFB2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPA2B1 SF3A1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CHERP SF3A1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 SAFB â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
PNN SF3A1 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SFPQ SRRT â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPA2B1 HNRNPH2 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 HNRNPC â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPA2B1 HNRNPA3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPC SRRT â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPC PNN â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
AKT1 GSK3B â—¼   DOWN_REGULATES ✅ - 0.82 0.82 Signor 15829723
AKT1 GSK3B â—¼   PHOSPHORYLATION ✅ - 0.82 0.82 Signor 23552696
ACTR2 ARPC1B â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 SAP18 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPH2 HNRNPK â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HNRNPH2 SFPQ â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CPSF4 HNRNPA3 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EGFR ANXA2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25136068 26320552
CTBP1 RBM14 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 30217970 31041561
TMOD1 MYO5C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 26496610
MYO5C TMOD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
SAP18 SF3A1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA2B1 SAFB2 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CPSF4 HNRNPL â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
SAFB SF3A1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RBM14 SAFB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ANXA2 S100A4 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NDN TP53 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HNRNPA2B1 SAFB â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
RBM14 SF3A1 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
HNRNPA2B1 SAP18 â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
FLOT1 SVIL â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
GSK3B SFPQ â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30711629 20932480
FAF1 CUL1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 22730322 28443643 18775313
ARPC4 ARPC1B â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
FLNA ARRB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17620599 16611986
EGFR EMD â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24797263 28065597 20937808
EMD SUN2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19933576 30833792
EPS15 STON2 â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 6179743 18200045
LIMA1 TWF1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 26496610
HNRNPL RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA3 RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTR2 CTTN â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
UBC USP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
ACTR3 ARPC2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPK HNRNPL â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
CAPZA2 S100B â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
S100B TP53 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CPSF4 RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA2B1 RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPL SAFB2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
RBM14 SAP18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPC RBM14 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
HNRNPA3 SAP18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ACTR2 ARPC3 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
ARPC1B ARPC2 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
SAFB2 SFPQ â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
TP53 S100A4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 19740107 7256480
SAFB SAP18 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ARPC2 ARPC3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA2B1 HNRNPK â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPC SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA3 HNRNPC â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPL SF3A1 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPK SFPQ â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
ARPC3 ARPC4 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
AKT1 FOXO1 â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 21798082
AKT1 FOXO1 â—¼   RELOCALIZATION ✅ - 0.85 0.85 Signor 18423396
CAPZA1 SH3KBP1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
HNRNPL SAFB â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
CHERP PNN â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
HNRNPA3 HNRNPL â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
SVIL LIMA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 20309963
SVIL FLNA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 20309963
CD81 EGFR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32900848 30024968
FLNA MYH9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
RAC1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21454543 31046837
WNK1 PLEC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27173435 30021884
ACTG1 CFL2 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
HNRNPA3 SAFB â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CFL2 DSTN â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
SAP18 SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
GSK3B TP53 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
SAFB SFPQ â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
HNRNPC HNRNPL â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
EGFR ARRB2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
MYL6B MYL6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22939629
S100A4 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EGFR SH3KBP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
HNRNPA3 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CPSF4 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
SF3A1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
COPS5 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
HNRNPA2B1 SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
EGFR UBASH3B â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
HNRNPL SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
HNRNPC SFPQ â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
FAF1 UBC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
HNRNPC SF3A1 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
CBL YWHAQ â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
HNRNPC SAP18 â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
BECN1 AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 29669822 23112296
FLNA ARRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17984062 17620599 16611986
PLS1 EGFR â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12871937 16713569 12009895
RBM14 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11443112 16713569 33742100
MAP1B LRRK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21159966 24754922
MYH9 S100P â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31837246 15171681
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EGFR EPS15 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
COBL PACSIN3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
AKT1 EP300 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EGFR HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HDAC6 HSP90AA1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PPP1CA URI1 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
HNRNPA2B1 HNRNPL â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
AKT1 PPP2CA â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
AKT1 FOXO1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HNRNPA2B1 HNRNPL â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
EGFR ACTN4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 26320552 25402006 24658140
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
EGFR ARRB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
CBL UBC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
EGFR HSP90AB1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HDAC5 YWHAQ â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RAC1 IQGAP1 â—¼   COLOCALIZATION ✅ 0.89 0.89 mint 18809683
ACTR2 CORO1C â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
RBM14 SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
ACTG1 CFL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
EP300 NCOA3 â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CBL LYN â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
HNRNPL SFPQ â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
SAFB SAFB2 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
STUB1 TP53 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
GSK3B GNB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FYN GSK3B â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 17607942 15676027 15652488
ANXA2 TRIM72 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 14506282 19380584 22421042
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
CBL PPP2CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11053437 12593796 12815057
CCR5 CXCR4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12429730 18632580 15660419
PPP2CA CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8864841 20133759 11093160
CSNK2A1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14675149 25862939
DAPK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17339337
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
STON2 EPS15 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19380743 18200045 11381094
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
TP53 HSPA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15212714 20097177 18840615
PPP1CB MYL6 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 410909200 8208729 15545284
TRPM6 TRPM7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24385424 14976260 26563869
S100A2 S100A3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ARPC2 ARPC4 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
ACTG1 DSTN â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EPS15 UBC â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
LRRK2 YWHAQ â—¼   PHYSICAL_INTERACTION 907.0 0.9 STRING 36370105
ACTR2 ARPC2 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
ACTR2 ARPC4 â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
HSP90AA1 STUB1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
TP53 USP7 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
S100B S100P â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
TP53 UBE3A â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CUL1 UBC â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CBL FYN â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
IQGAP1 RAC1 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CBL SH3KBP1 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
AKT1 GSK3B â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
S100A4 S100B â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
S100A1 S100A4 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
CAPZA1 S100B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
S100A2 S100B â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
AKT1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
S100A1 S100P â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
S100A1 S100A2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
EPS15 STON2 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PNN SAP18 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
S100A1 S100B â—¼   PHYSICAL_INTERACTION 0.95 0.95 HuRI 32296183
PPP1CB PPP1R12A â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
CAPZA1 CAPZA2 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
PAWR DAPK3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 12917339 15001356 10602480
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
PPP2CA PPP2R4 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
ARPC4 ARPC3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 11162547 32296183 24981860 26344197 22939629 23148219 22863883
SH3KBP1 CBL â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6170483 15090612
FYN CBL â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9677430 8621719 12244174 7782294 10629042 119942 7642581 15556646 12231245 9311917 9535867 8626543 10799548 16713569 16503409 10092522 8900205 8995358 25814554 9890970 15190072 15208330 12941616 10829062 11239464 8662998 17094785
S100B S100A1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 8153045 21516116
USP7 TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5215220 11923872
TP53 USP7 â—¼   DEUBIQUITINATION ✅ 0.97 0.97 mint 5215220 11923872
MYH9 S100A4 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
SH3KBP1 UBC â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC6 UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CREBBP NCOA3 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
AMFR UBC â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
UBC USP7 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CREBBP TP53 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
ACTR3 ARPC5L â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
BOP1 PES1 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
ACTR2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC1B ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC2 ARPC5L â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
ARPC4 ARPC5L â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
ARPC3 ARPC5L â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
ACTR3 ARPC1B â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ACTR2 ARPC1B â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ARPC1B ARPC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ARPC1B ARPC2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ARPC1B ARPC4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
AKT1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 99.0 1.0 Omnipath 17428466 15207235 17145710 12052830 10729337 8250835 11756412 11923280 16914735 17623045 16697215 8524413 12054501 20398329 18372248 21506126 20028971 12040186 15808505 16543730 20138985 23331499 21303971 16009706 10385618 20214616 23180781 9373175 16039586 15829723 18988627 16282323 11577096 11035810 18669648 18216173 15169778 12851486 16123141 11882383 23109003 9065430 18691976 22094462 10949026 22710759 11715018 12459251 18636226 17192257 11254732 11278246 20858269 9812896 9582355 15023346 17680028 19369195 7945242 12900420 23552696 18387957 10722653 20832730 18570873 12147701 18505846 17052453 17693255 18218901
GSK3B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23840442 12064478 11709713 9372954 11483158 16552184 17570479 14744935 16713569 21929745 12048243 21900206
GSK3B SFPQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 20932480
GSK3B MAP1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 27849007 25775433 15731007 17570479 9570753 25040932
AKT1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CUL1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11516665 12820959 15071497 15147722 15340381 15459660 15668399 15688063 18931676 19622404 19686080
AKT1 CUL1 â—¼   DOWN_REGULATES ✅ - 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
CSNK2A1 ACE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 16186248 15569856 16476786 21901117 12386153 14615289
CFL2 ACTC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16530787 18957424
CFL1 ACTC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12207032 16713569 17196218
RAC1 ACTG1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 18391171 16262445 11231582 9600938 15040784 12743368
ACTR2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ACTR3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR2 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ACTR2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
ACTR3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC2 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ACTR3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ACTR3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
RAC1 AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
AKT1 FOXO1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 15987244 10358075 10102273 12857750
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
HSP90AA1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19356729 18266962 10995457 25714412 16189514 12176997 12586360 15843522
CSNK2A1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 29732088 17374729 21506126 11689703 10671551 12149249 15818404 10747897 10837139 20976471 19662498 21285348 11035045 11707428 21735093 17444818 20558317 11972058 16707567
PPP2CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 21159657 26256536 15743829 10026142 20452955 11438723 18559511 11839802 19996169 19216069 16406523 10995457 18042541 19556239 18588945 16680151 11087733 18160256 15367694 18039929 18077353 11812651 16044149 20360384 12637511
PPP1CB AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
LRRK2 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 24916379 21658387
RAC1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 16697215 20398329 17461779 18372248 20338997 15808505 20138985 20214616 21474067 19568798 15169778 19720745 18925875 10949026 11715018 19143635 12393431 18636226 10617634 9812896 17680028 19151919 10722653 20832730 18570873 17052453 12408816 11274345
PPP1CA AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20186153 14633703
AKT1 FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 21440011 10358014 11756412 10358076 31308176 20452955 21798082 11410590 20398329 11311120 11544290 28279977 10217147 15132996 23331499 19216069 11237865 20214616 11463845 16076959 11030146 12228231 9829964 18951090 23180781 17570479 10102273 18593906 17646672 16680151 12456685 18423396 18985696 18988627 17962350 30728292 16670091 18786403 14664696 25241761 16341064 11980723 10358075 2984676 13679577 12560069 10377430 11251083 17680028 2987962 17254970 11864996 20041807
AKT1 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 17623675 18182168 16926151 20333651 19158375 17964260 17570479 11116148 25904863 21901101 23275565 16024795
AKT1 YWHAQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 20138985 15169778 9812896 17680028 11756412 11923280 20214616 16697215 10949026 10722653 20832730 18570873 18372248 11715018 20398329 17052453 18636226 15808505
AKT1 WNK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21355052 16081417 14611643 22119528
ARPC2 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC2 ARPC3 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ARPC2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
ARPC3 ARPC4 â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
ARPC3 ARPC4 â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 10467124 10511705 10783245 11395419 11520460 12177428 12194823 14707117 15001467 15541654 16293614 16606694 17306570 19741094 21178402 23212475 8625410
MYH9 ARPC3 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
MYH9 ARPC4 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 12194823 16606694 19349987 21840487 24857661 25712372
PPP2CA ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
CSNK2A1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11877451 32863206
PPP2CA ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
BECN1 PIK3C3 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 PIK3C3 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 17106237 17446862 18612260 22093031 22166994 22421439 22885520 23030059 23301705 23377657 23725295 24070470 27754749 28645028
BECN1 PIK3C3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 18628207 36042481 19713971 19050071 16179260 25594178 21936852 18843052 24980959 28128446 25906440 26496610 26783301 23954414 19379691 23332761 20562859 23974797 24034250 16390869 24980960 19270696 25825496 19172397 20711182 23315026 25490155 24472739 17438366 23364696
CSNK2A1 CAPZA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15831458
HSP90AA1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
SH3KBP1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 20130058 20711168 12618476 11894095 16407834 16713569 11071869 19268472 25472714 17306257 22262777 15456872 11152963 10679202 15962011 25036637 15107835 22833562 11067845 11894096 12177062 17675467 21830225 12135478 24167568 16228008 12874286 17072306 15090612 14596919
FYN CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 97.0 1.0 Omnipath 9525940 7642581 8626543 7782294 15208330 16503409 16713569 10829062 10799548 10934191 8900205 8551236 8662998 8995358 19734451 12604776 9890970 10592173 17570479 10629042 17094785 10092522 11997497 12522270 15556646 12244174 8621719 9102067 22880054 9311917 11239464 19904769 11994282 12941616 9535867 25814554 12231245 15190072
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL LYN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 12149655 18235045 12244174 8627181 8621719 7782294 15304502 9160881 15190072 7721825
CBL SORBS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12475393 15128873 20886612
EGFR CCDC50 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19059208 15951569
SSH2 CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11832213 14531860 16713569
CSNK2A1 CORO1C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23410663 22355754
TP53 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 19057620 15632413 11466559 19448667 19880525 9891054 22198284 10833421 11709699 10435630 11390631 9890939 21191649 12501250 11928223 17434128 12164786 24330748 11779500 10435595 21513889 10777477
NCOA3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10777539 14966289 22977234 15798179 22608253 11747826
CREBBP TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 49.0 1.0 Omnipath 17303408 25545885 27618436 19220000 16713569 10823891 15632413 19805293 25451029 15279786 10473588 12154097 7575488 16537920 10848610 18485870 19880525 10648616 20144767 14722092 14759370 18590585 26976603 9194564 19788416 25314079 19166313 12426395 9288775 11782467 17660363 19234109 21390126 10196247 17434128 19357310 10551785 22084066
CSNK2A1 FAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 12832043 11378439 11713579
CSNK2A1 TERF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18347021
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CSNK2A1 MYH9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 22123909 18971378 30087119 17567956 24462114 30267961 19826041 21316371
CSNK2A1 MME â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22767595 20957047
CSNK2A1 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 15822905 17081983 16565220 18088087 29854279 2492519 34359868 25995454 1956339 16094384 15581363 18591256 16964243 92065884 15302935
CSNK2A1 HNRNPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19651622 20058876 17081983 20166139 15687492 18691976 20068231 18452278 19664995 17693683 17287340 19413330 12564933 18669648 15302935
HDAC6 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21220424 21847094 17643370
ROCK1 DAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15611134 25769953 17158456 16325270 20854903 18239682
DAPK3 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11226254 24712327 23345589
DAPK3 MYL12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15096528 10356987 11781833
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
PPP2CA EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18039929 16680151 10995457 18042541 18588945
LYN EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 17145710 31980649 16799092 23866081 24658140 11160627 23764002 25402006 22430206
EGFR EPS15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 17145710 17389395 10953014 24269888 19534553 25260758 19583965 19690332 15951569 9049247 17016520
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
EPS15 SH3KBP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
FYN SH3KBP1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 17350651 23052211 23506116 16529723
HDAC6 HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19158084 18591380 18266962
HNRNPK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18472002 16360036 23092970
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TP53 HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15052775 15284248 21478269
TP53 HSP90AB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23443559 18431400 11707401 22939624
MEN1 IQGAP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 19737400 9694656 10473551 19079338
IQGAP1 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 31980649 28007913 8798539 19079338 9199170 8670801 8702968 15695813 15217908 8756646 18809683
LYN NEDD9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9020138
ROCK1 MYH9 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10652353 11698448 12194823 12778124 19349987 27785353
PPP1R12A MYH9 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
MYH9 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
S100A4 MYH9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9405067 22460785 15289939 16707441 22483112 31837246 20421509
ROCK1 MYL12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8702756 11283607 26169356 12185584
PPP1R12A MYL6 â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
NDN TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24722188 10347180 16713569 23785149
PPP1CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 16501611 16713569 15231748 15178317
PPP1CB ROCK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PPP1CB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16501611 15178317
PPP1R12A ROCK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
ROCK1 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 11384979 15723050 18767875 19607793 19701943 9354661 10926869 18077418 18669648 10579722 15826939 12220642 26701920 17525332 19997641 12600888 11931630 11719507 15814590 8662509 12563012 12919947 10601309 18212344 12359219
PPP2CA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 17245430 14712210 1848668 16713569 12556559
TP53 S100A2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 18431400 18388131 22747445 10094469 24556685 21394211
TP53 S100A2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15941720 20591429 31837246 18431400
TP53 S100A4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 19740107 15116098 23752197 20591429 20070253 11527429 12942774 31837246 11278647
S100A4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 19740107 15116098 23752197 20591429 20070253 11527429 12942774 31837246 11278647
TP53 S100B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20587415 21546003 15178678
TP53 S100B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20591429 11527429 16713569 10876243 31837246
TP53 USP7 â—¼   CLEAVAGE ✅ 4.0 1.0 Reactome 16402859 15053880 16474402 11923872
UBE3A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 25.0 1.0 Omnipath 23040663 7724550 9450543 16713569 16493710 15001357 17131388 9143503 19364824 31971989 11027293 9688277 9369221 1661671 7708685 12620801 8090726 8380895 26789255
USP7 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26460617 21845734 23382381 16713569 25283148 15916963 18375498 19918835 24462112 22056774 17268548 22653443 23388826 21170034 20816748 17525743 16402859 11923872 17380154 16082221 26238070 16845383 16474402 35538032 22084066