Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ABL1 SHANK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
SHANK3 DLGAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 LZTS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 DLGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
SHANK3 SORBS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ABL1 EFS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DLGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 DLGAP4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
ABL1 ADAM15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214905 11741929
BCKDK SORBS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAE CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
SFN CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11697890 8005785
YWHAZ CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217069 15225635
EGFR YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5217069 15225635
FLNA YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
YWHAZ LIMA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
PPP1CB MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23277204
MYH9 PAK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 10639334 10047984
PAK2 SORBS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218167 16374509
YWHAB PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
PTPN12 WAS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216858 14707117
SORBS2 SFN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15778465 5217604
SMARCA4 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20129940 8009769
SYNJ1 SORBS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11292345 5213923
WASF1 SORBS2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213352 11130076
SORBS2 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
SORBS2 YWHAE â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
VCL YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ERCC5 SORBS2 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
PTPN12 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 28065597
CBL YWHAB â—¼   PHYSICAL_INTERACTION 819.0 0.81 STRING 36370105
ANLN ACTN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN FLNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN SYNPO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN MYH9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN MYO1C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
ANLN LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
MYO1C CBL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19380743 9367879
EGFR LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24797263 31980649
NCK2 WASF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HuRI 32296183
NCK2 ABL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NCK2 CBL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24287595
ABL1 EGFR â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
PALLD ACTN1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16125169 15147863
FLNA MYH9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
WASF1 ABL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10970852 18559503
ACTN1 VCL â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
EGFR YWHAZ â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EGFR SFN â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SYNPO ACTN1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26496610 30021884
YWHAB YWHAE â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EGFR NCK2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAB YWHAZ â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ABL1 ABL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27229929 12569093 15735735
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
YWHAE YWHAZ â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
ABL1 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12110584 25624478 16702947
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
NCK2 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 22973453 9843575 16713569 25402006 1333047 10026169 9737977
EGFR PTPN12 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 21376233 7542744 7541030
SFN MDM2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 8007833 17546054 1210540
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
NR1H2 SORBS2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NR1I2 SORBS2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19129222
YWHAZ SFN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
SFN YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23840115 15161933
NCK2 PAK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
ABL1 CBL â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
YWHAZ YWHAE â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20618440 7899808
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 CBL â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 10837221 15459660 18835194 21051857 21199784 21435002
PAK2 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 18161990 20841568 11121037
PTPN12 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15588985 11163214
ABL1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 9525940 11494134 16713569 20841568 10829062 17389395 16955467 12604776 9890970 10391678 9195915 14725908 7925293 11997497 12522270 15556646 9102067 11239464 11994282 9174058 12475393 20675402 19380743 14604282 8626543 15212693 19823681
ABL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 23331499 12110584 20651945 29065514 22352870 16702947 25973395 27626309 21081495 27956626 20841568 14757045 19738896 15212693 28690977
ABL1 SORBS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 23331499 24475245 12475393 18559503 21071413 9211900 20841568 18768933
ABL1 ABL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12569093 15735735 20841568
ABL1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 15686624 9109492 9295282 9312071
ABL1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 55.0 1.0 Omnipath 24430869 15192046 33889303 16273093 16943190 14760089 29880877 15618223 33574089 8910327 12631709 25173817 25402006 20841568 33947961 34107301 34469737 19915609 32019812 2022651 34290403 33707748 15329413 7678409 9733788 8490966 28338646 3263271 15901825 2022652 10069801 7506413 24658140 8408058 34385595 31980649 1314835 7741752 18668345 28724430 12648464 25073158 26079946 34155348
ABL2 SORBS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 21071413 9211900 20841568
AKT2 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19216069 17680028 11756412 16680151 20214616 11463845 20452955 9829964 20398329 11504915 17646672 10217147
PTK2B CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11149930 15128873 16713569
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL SORBS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12475393 15128873 20886612
PTK2B EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14963038 11274221 16713569 10777553
EGFR NCK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 1333047 23331499 10026169 9737977 24658140 16713569 25402006 9843575 1333046
EGFR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23956138 23178489 18237807 18789131
MYH9 PPP1CB â—¼   DEPHOSPHORYLATION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
PRKDC POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
YWHAB PPP1CB â—¼   DEPHOSPHORYLATION ✅ 14.0 1.0 Reactome 16294014 21779496 24211266 27264673 19684605 16041367 24347342 16630891 28666118 12932319 11756411 25907612 14530258 28289718
PTPN12 PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12231407 15588985 11337490
PTPN12 WAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11711533 15588985 19167335 14707117
YWHAE YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAB YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20936779 17085597 12507503 24255178 17979178
YWHAZ YWHAE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
YWHAE YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 21988832 20936779 20618440 26496610 16376338 17979178 19766566
POLM WASF1 â—¼   KO_DOWN_REGULATES ✅ - -1.02 1.01 PKG 28854368
POLM SORBS2 â—¼   KO_DOWN_REGULATES ✅ - -1.12 1.11 PKG 28854368
PRKDC SORBS2 â—¼   KO_DOWN_REGULATES ✅ - -1.27 1.26 PKG 28854368
ERCC5 ERCC5 â—¼   KO_DOWN_REGULATES ✅ - -1.7 1.69 PKG 28854368
POLB SORBS2 â—¼   KO_DOWN_REGULATES ✅ - -1.91 1.9 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368