PCNA
|
XPC
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19279666
7263364
|
RAD23B
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16712842
5218673
|
TP53BP1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15970701
21914189
|
GTF2H3
|
ERCC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8652557
10734072
|
ERCC3
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
ERCC5
|
ERCC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8652557
|
GTF2H4
|
ERCC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9118947
10734072
|
ERCC4
|
XPC
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19279666
7263364
|
XPA
|
ERCC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17948053
|
ERCC5
|
EWSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16713569
5218676
|
ERCC8
|
XPA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8999876
|
GTF2H1
|
XPC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11259578
26278177
|
GTF2H2
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
GTF2H3
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
GTF2H4
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
GTF2H5
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
800.0
|
0.8
|
STRING
|
36370105
|
HSPB1
|
TDG
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RAD23B
|
TDG
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16713569
12505994
|
GTF2H3
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
GTF2H2
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
804.0
|
0.8
|
STRING
|
36370105
|
ERCC5
|
COX7A2L
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.81
|
0.8
|
PKG
|
28854368
|
ERCC2
|
GTF2H3
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
ERCC5
|
DOHH
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.81
|
0.8
|
PKG
|
28854368
|
CCNH
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
ERCC5
|
SORBS2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.8
|
0.8
|
PKG
|
28854368
|
ERCC3
|
GTF2H3
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
GTF2H2
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
816.0
|
0.81
|
STRING
|
36370105
|
GTF2H3
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
819.0
|
0.81
|
STRING
|
36370105
|
ERCC5
|
TF2H2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
8652557
33961781
|
DDB2
|
COX7A2L
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.83
|
0.82
|
PKG
|
28854368
|
DDB2
|
PGK1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.82
|
0.82
|
PKG
|
28854368
|
XPC
|
RAD23B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
34591642
|
RPA1
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
ERCC5
|
ANXA2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.84
|
0.83
|
PKG
|
28854368
|
ERCC6
|
HMGCR
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.84
|
0.84
|
PKG
|
28854368
|
GTF2H5
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
XPC
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
17154534
12486030
|
TDG
|
DTL
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.85
|
0.85
|
PKG
|
28854368
|
ERCC2
|
GTF2H4
|
â—¼ CORRELATES
|
|
+
|
0.85
|
0.85
|
CCLE
|
31978347
|
BRCA1
|
RFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
25184681
10783165
16713569
|
NTHL1
|
ERCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15358233
16713569
9927729
|
GTF2H3
|
GTF2H4
|
â—¼ CORRELATES
|
|
+
|
0.86
|
0.86
|
CCLE
|
31978347
|
ERCC2
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
ERCC4
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
862.0
|
0.86
|
STRING
|
36370105
|
ERCC4
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
GTF2H5
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
864.0
|
0.86
|
STRING
|
36370105
|
PGK1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26030842
20849852
|
TF2H1
|
ERCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
15195146
16713569
8652557
11259578
|
TCEA1
|
CDK7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26186194
9305922
|
XPA
|
ERCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20541997
8999876
|
ERCC6
|
ERCC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
ERCC3
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
GTF2H4
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CDK7
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
PCNA
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
BRCA1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.87
|
STRING
|
36370105
|
TCEA1
|
TF2H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10454562
9765293
9305922
|
ERCC6
|
ERCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
8652557
16916636
16713569
16246722
|
DDB2
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
ERCC3
|
GTF2H4
|
â—¼ CORRELATES
|
|
+
|
0.88
|
0.88
|
CCLE
|
31978347
|
PCNA
|
ERCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
10408173
16189514
9305916
16713569
|
CDK7
|
ERCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17643375
33961781
29568061
23602568
32707033
|
XPC
|
ERCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
26278177
10734143
|
ERCC5
|
ACAD10
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.89
|
0.89
|
PKG
|
28854368
|
ERCC2
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
896.0
|
0.89
|
STRING
|
36370105
|
ERCC1
|
MUS81
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
PCNA
|
ANXA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26030842
16189514
12171929
20849852
|
PCNA
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16861906
25154416
21725088
30301766
30623174
29424068
20129063
|
CDK7
|
TF2H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9130708
8521393
9852112
26340423
7533895
29568061
23602568
28977422
32707033
8692841
|
CCNH
|
TF2H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9852112
26340423
7533895
10734143
33707221
11259578
|
TF2H1
|
ERCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9130708
26340423
8152490
11071939
8652557
|
XPC
|
TF2H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26278177
10734143
11259578
|
TF2H1
|
ERCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15220921
17643375
33961781
9130708
24981860
9173976
26344197
22939629
26340423
33453189
19934020
8194528
10403766
8692842
8652557
28514442
9118947
11259578
|
TF2H2
|
ERCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15220921
17643375
33961781
24981860
26344197
10924514
26340423
8194529
33453189
28977422
8652557
28514442
9118947
16189514
19934020
|
RAD51
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11498787
31270457
19369211
14636569
24085845
29656893
28319063
25659039
34408138
31009828
9774970
16713569
25499220
19766185
17302439
9008167
28976962
|
BRCA2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14499622
25652403
17664283
19369211
14636569
24085845
29656893
34408138
11477095
9774970
16713569
21135251
25184681
|
PALB2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
22331464
19369211
19268590
29656893
25016020
30337689
28319063
28089683
19553677
25652403
22193777
34408138
23585894
23038782
19584259
26649820
24085845
25184681
28398198
|
BRCA1
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16713569
9774970
9008167
|
PALB2
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
22331464
19369211
19268590
26990772
30410870
20871615
25016020
16793542
28319063
24835992
17420451
24141787
19553677
22193777
24485656
23585894
17200672
21466675
23038782
28240985
26833090
20332121
19584259
26649820
22293751
19609323
28765325
28398198
|
CCNH
|
GTF2H4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19172752
26340423
10734072
|
CEBPG
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
2404278
9668047
8817653
|
ERCC1
|
ERCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14517266
19940136
17948053
|
ERCC1
|
RAD51
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
14734547
17962301
18541667
|
ERCC5
|
ERCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
8652557
16189514
16713569
32245994
|
GTF2H3
|
ERCC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9118947
8652557
10734072
|
RPA1
|
ERCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14517266
19940136
17948053
|
RPA3
|
ERCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14517266
19940136
17948053
|
ERCC5
|
ERCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14517266
19940136
17948053
|
RPA2
|
ERCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
14517266
19940136
17948053
|
RAD51
|
ERCC4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
14734547
17962301
18541667
|
GTF2H3
|
GTF2H2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
8652557
15790571
10734072
|
GADD45A
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
PALB2
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
RPA2
|
RPA3
|
â—¼ CORRELATES
|
|
+
|
0.9
|
0.9
|
CCLE
|
31978347
|
XPC
|
SPP1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.9
|
0.9
|
PKG
|
28854368
|
PALB2
|
BRCA1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
28319063
|
BRCA1
|
PALB2
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
8329239
22193777
|
ERCC5
|
GTF2H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
ERCC5
|
EIF4EBP2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.91
|
0.91
|
PKG
|
28854368
|
RPA1
|
TP53BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
RPA3
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
24126761
|
ERCC2
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
ERCC6
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
923.0
|
0.92
|
STRING
|
36370105
|
GTF2H4
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
928.0
|
0.92
|
STRING
|
36370105
|
TDG
|
TF
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.93
|
0.93
|
PKG
|
28854368
|
GTF2H1
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
GTF2H1
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
CDK7
|
GTF2H5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
936.0
|
0.93
|
STRING
|
36370105
|
CDK7
|
GTF2H4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
ERCC4
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
CCNH
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.93
|
STRING
|
36370105
|
BRCA1
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
RAD51
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.94
|
STRING
|
36370105
|
ERCC5
|
TDG
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.96
|
0.95
|
PKG
|
28854368
|
GTF2H1
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
TF2H1
|
TF2H2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
33961781
9130708
24981860
26344197
10924514
11062469
8194529
26340423
21988832
8652557
28977422
19934020
|
TF2H2
|
CCNH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
10924514
11062469
26340423
33707221
19934020
|
ERCC6
|
SLC16A3
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.97
|
0.96
|
PKG
|
28854368
|
ERCC3
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
966.0
|
0.96
|
STRING
|
36370105
|
ERCC5
|
PGK1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.96
|
0.96
|
PKG
|
28854368
|
TF2H2
|
ERCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9771713
27193682
10924514
11062469
26340423
8652557
12820975
16189514
19934020
|
CDK7
|
TF2H2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
17643375
9130708
10924514
11062469
29568061
23602568
28977422
19934020
|
CDK7
|
CCNH
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
22939629
16782892
26340423
9218599
15698475
23602568
17643375
26344197
33453189
10082552
33707221
15328539
32707033
8692841
33476598
9334327
28514442
9056480
8078587
10958691
11713533
8521393
8521818
11113184
26186194
29568061
|
XPA
|
ERCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
28514442
33961781
18597777
7876167
19056823
32296183
24036546
7598728
8197174
26186194
9653453
9013642
16491090
25416956
8972858
17948053
11058119
|
ERCC3
|
ERCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
15220921
27193682
16669699
33381997
22939629
26340423
8152490
8652557
9118947
22678362
19934020
|
DTL
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
GTF2H2
|
GTF2H5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
GTF2H1
|
GTF2H5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
RAD23B
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
ERCC2
|
GTF2H5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
RAD51
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219969
17541404
|
BRCA2
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
CDK7
|
GTF2H2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
RPA1
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
LIG1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
CDK7
|
GTF2H3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
990.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
ERCC2
|
GTF2H4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
DDB2
|
ANXA2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.0
|
0.99
|
PKG
|
28854368
|
BRCA1
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
CDK7
|
POLR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
ERCC5
|
LHPP
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.99
|
0.99
|
PKG
|
28854368
|
POLR2A
|
TCEA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CDK7
|
ERCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
ERCC2
|
GTF2H3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
GTF2H3
|
GTF2H5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CCNH
|
GTF2H3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RPA1
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
ERCC1
|
ERCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCNH
|
GTF2H4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCNH
|
ERCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCNH
|
GTF2H5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCNH
|
ERCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ERCC3
|
GTF2H4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ERCC3
|
GTF2H3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ERCC3
|
GTF2H5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
ERCC3
|
GTF2H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
GTF2H1
|
GTF2H3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
GTF2H1
|
GTF2H4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
GTF2H3
|
GTF2H4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
GTF2H4
|
GTF2H5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CCNH
|
CDK7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNH
|
GTF2H2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNH
|
GTF2H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CDK7
|
GTF2H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CDK7
|
ERCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
ERCC2
|
GTF2H2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
ERCC2
|
GTF2H1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
ERCC2
|
ERCC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
ERCC3
|
GTF2H2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
GTF2H1
|
GTF2H2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
GTF2H2
|
GTF2H3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
GTF2H2
|
GTF2H4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
RPA2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
PCNA
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
GADD45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
10779360
11756412
12124778
14624239
14726013
15703371
15917306
16697054
17599061
19004803
19652693
1974050
19847258
20457011
22021614
22615860
23414611
23485469
|
PCNA
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
RPA2
|
PCNA
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
PCNA
|
BRCA2
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
LIG1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
BRCA1
|
â—¼ SHARES_COMPLEX
|
|
|
49.0
|
1.0
|
ACSN
|
11756412
11850621
11877377
11927554
12239151
12551922
12607003
14624239
14726013
15459660
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18809224
18931676
19075014
19217432
19264559
19622404
19686080
1974050
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20723763
21060331
21337561
21376743
21574959
22021614
22101340
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PCNA
|
GADD45A
|
â—¼ REGULATES
|
✅
|
|
18.0
|
1.0
|
ACSN
|
10779360
11756412
12124778
14624239
14726013
15703371
15917306
16697054
17599061
19004803
19652693
1974050
19847258
20457011
22021614
22615860
23414611
23485469
|
ERCC5
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
18079701
10408173
16713569
19279666
9305916
20713449
|
GADD45A
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
7784094
23485469
10973963
7973727
10828065
16189514
20460379
7478510
|
LIG1
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12171929
9649448
28073635
10559261
|
PCNA
|
RFC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8999859
12400013
15225546
19285992
10353443
12192049
9649448
26496610
12045192
12171929
24958773
8861969
9092549
|
RPA2
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
LIG1
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
LIG1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
BRCA1
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
BRCA2
|
â—¼ SHARES_COMPLEX
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
TP53BP1
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
ACSN
|
11042216
11877378
17243194
18087291
19342239
20646866
9748285
|
BRCA1
|
XPC
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10367887
10779360
10962562
11877377
12024039
12170778
12496474
12771027
15242590
15459660
15485915
16818604
19004803
19357644
19686080
19788416
19793801
20029420
21060331
21337561
9346961
9892649
|
BRCA1
|
DDB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10367887
10779360
10962562
11877377
12024039
12170778
12496474
12771027
15242590
15459660
15485915
16818604
19004803
19357644
19686080
19788416
19793801
20029420
21060331
21337561
9346961
9892649
|
BRCA1
|
GADD45A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17428466
11777930
10962562
18025037
18350249
12647291
|
BRCA1
|
PALB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
26649820
19268590
28089683
28319063
19369211
|
BRCA1
|
GADD45A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
12771027
9346961
10779360
11877377
10367887
19004803
21060331
12496474
19793801
15650754
10962562
21337561
9892649
10528224
15459660
20029420
|
BRCA2
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
PALB2
|
BRCA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
17420451
16793542
26990772
19268590
22293751
17488615
19369211
23585894
24485656
20332121
24141787
26649820
19553677
17200672
26833090
23038782
17200668
15115758
19609323
30410870
19584259
22193777
|
BRCA2
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
87.0
|
1.0
|
Omnipath
|
17145710
21601571
15937124
17541404
11313963
16914443
26145171
21670257
18264088
19303847
25585578
12815053
16793542
21789034
25282148
17515904
9126738
20729859
15703751
21076401
15065660
22293751
19875419
12606939
22116401
12619154
23935068
15800615
33476590
15800651
15671039
11477095
16513631
9811893
10551859
20729832
9523196
14636569
17515903
12442171
9405383
26833090
21399666
19628690
9560268
10373512
14580352
|
CCNH
|
CDK7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
23602568
11113184
8521818
16782892
15698475
15328539
19153657
10082552
26340423
8692841
26186194
9334327
10958691
10734072
9056480
9218599
8078587
8521393
17643375
|
RPA2
|
CDK7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
ERCC1
|
CDK7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
CDK7
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
CDK7
|
XAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
RPA2
|
CDK7
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
ERCC1
|
CDK7
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
CDK7
|
XAB2
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
CDK7
|
XPA
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
CDK7
|
POLR2A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
25.0
|
1.0
|
Omnipath
|
18079403
27197304
26799765
10886368
14662762
16327805
24662513
26748711
25561469
21331744
19667075
18079404
22137580
9130709
20457598
19901026
19450536
20932174
|
XPA
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11278856
23038248
18614043
25154395
14517266
19056823
20368362
|
DDB2
|
XPC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
15882621
22039351
19740755
29604309
23319653
|
RPA1
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
RPA2
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
RPA3
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
RPA2
|
ERCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
ERCC1
|
XAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
ERCC1
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
RPA2
|
ERCC1
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
ERCC1
|
XAB2
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
ERCC1
|
XPA
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
XPA
|
ERCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
19056823
26186194
8972858
18597777
25416956
9653453
7876167
11058119
17948053
7598728
8197174
16491090
|
GTF2H1
|
ERCC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9130708
8652557
10734072
|
ERCC5
|
ERCC2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8652557
16713569
20840796
|
ERCC2
|
ERCC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10734072
8652557
10024882
16669699
|
ERCC2
|
GTF2H2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
12820975
10734072
9771713
8652557
16189514
19934020
|
GTF2H1
|
ERCC3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
10403766
10734072
9173976
8194528
15220921
9118947
9130708
8652557
11259578
26340423
17643375
|
ERCC3
|
GTF2H2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9118947
8652557
16189514
10734072
|
RPA2
|
ERCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
17000769
9699634
7700386
15590680
9716411
17466625
|
RPA1
|
ERCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
17000769
9699634
7700386
15590680
9716411
17466625
|
ERCC5
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
17000769
9699634
7700386
15590680
9716411
17466625
|
ERCC6
|
ERCC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16916636
8652557
16713569
16246722
|
ERCC5
|
GTF2H1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15195146
16713569
8652557
11259578
|
ERCC8
|
ERCC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
22902626
16751180
7664335
20541997
16916636
26826127
22032989
|
ERCC6
|
XAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17145710
10944529
|
ERCC8
|
XAB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
17145710
10944529
|
GTF2H1
|
GTF2H2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
21988832
10734072
11062469
9130708
8652557
8194529
|
PALB2
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19423707
20871616
24141787
|
XPA
|
RAD23B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11278856
23038248
18614043
25154395
14517266
19056823
20368362
|
RPA2
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
XPA
|
RPA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
12527904
19446504
7665601
8972858
7876167
20304803
7565690
9535929
|
RPA2
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
RPA2
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
XAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
RPA2
|
XPA
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
RPA2
|
RPA3
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
XAB2
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
RPA2
|
RPA3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
XPA
|
RPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
12527904
19996105
10982866
8972858
20304803
7876167
11081631
7565690
32296183
20670893
9535929
|
TDG
|
XPC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
16713580
17129768
17855402
17884153
18199748
18543256
19809470
19847258
20211143
|
TDG
|
XPC
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
11900249
12648680
14726013
15703371
16697054
16713580
17129768
17855402
17884153
18199748
18543256
19809470
19847258
20211143
|
XPA
|
XAB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
TDG
|
FGF2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.02
|
1.02
|
PKG
|
28854368
|
DDB2
|
DOHH
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.19
|
1.18
|
PKG
|
28854368
|
TDG
|
SLC16A3
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.19
|
1.18
|
PKG
|
28854368
|
ERCC6
|
ERCC6
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.24
|
1.23
|
PKG
|
28854368
|
XPA
|
HMGCR
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.28
|
1.27
|
PKG
|
28854368
|
ERCC5
|
SLC16A3
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.29
|
1.29
|
PKG
|
28854368
|
ERCC5
|
ERVH48-1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.3
|
1.3
|
PKG
|
28854368
|
ERCC5
|
RBM46
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.31
|
1.3
|
PKG
|
28854368
|
DDB2
|
ERVH48-1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.33
|
1.33
|
PKG
|
28854368
|
ERCC5
|
MSL3P1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.35
|
1.34
|
PKG
|
28854368
|
XPA
|
SPP1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.35
|
1.34
|
PKG
|
28854368
|
ERCC5
|
FGF2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.36
|
1.35
|
PKG
|
28854368
|
DDB2
|
ACAD10
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.36
|
1.36
|
PKG
|
28854368
|
ERCC5
|
TF
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.39
|
1.38
|
PKG
|
28854368
|
ERCC5
|
HMGCR
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.4
|
1.39
|
PKG
|
28854368
|
ERCC5
|
SPP1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.41
|
1.4
|
PKG
|
28854368
|
TP53BP1
|
SPP1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.53
|
1.53
|
PKG
|
28854368
|
DDB2
|
HMGCR
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.56
|
1.55
|
PKG
|
28854368
|
ERCC5
|
ERCC5
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.7
|
1.69
|
PKG
|
28854368
|
TDG
|
SPP1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.74
|
1.74
|
PKG
|
28854368
|
DDB2
|
FGF2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.76
|
1.75
|
PKG
|
28854368
|
ERCC6
|
FGF2
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
2.14
|
2.14
|
PKG
|
28854368
|
DDB2
|
SLC16A3
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
2.32
|
2.32
|
PKG
|
28854368
|
DDB2
|
SPP1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.54
|
2.53
|
PKG
|
28854368
|
DDB2
|
TF
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.59
|
2.58
|
PKG
|
28854368
|
XPA
|
SLC16A3
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
2.73
|
2.73
|
PKG
|
28854368
|
ERCC6
|
SPP1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
2.77
|
2.77
|
PKG
|
28854368
|
ERCC5
|
INS
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.1
|
3.09
|
PKG
|
28854368
|
XPC
|
XPC
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.23
|
3.22
|
PKG
|
28854368
|
TDG
|
TDG
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.98
|
3.97
|
PKG
|
28854368
|
MUS81
|
SPP1
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
4.3
|
4.3
|
PKG
|
28854368
|
DDB2
|
DDB2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-5.71
|
5.7
|
PKG
|
28854368
|
TP53BP1
|
TP53BP1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-9.54
|
9.53
|
PKG
|
28854368
|