NHEJ1
|
XRCC4
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
FOXO3
|
ATM
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18344987
18424439
|
CREB1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20864035
|
TP53
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10823891
5212595
|
CREBBP
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10973497
|
CREBBP
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20428248
|
CREM
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18721873
12533437
|
TP53
|
DDB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11971958
|
SREBF2
|
INSIG1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15073165
|
SREBF1
|
INSIG1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15073165
|
RNF139
|
INSIG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
20068067
|
MYC
|
PRKACA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15197457
12420224
|
VCP
|
PPARA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
SYVN1
|
TP53
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17170702
5219455
|
UBC
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6603858
18588880
|
CREB1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
ATM
|
WRN
|
â—¼ PHOSPHORYLATION
|
|
|
0.8
|
0.8
|
Signor
|
10608806
|
FOXO3
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
808.0
|
0.8
|
STRING
|
36370105
|
CREBBP
|
FOXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
817.0
|
0.81
|
STRING
|
36370105
|
CREBBP
|
FOXO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
822.0
|
0.82
|
STRING
|
36370105
|
ATM
|
MDC1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.82
|
0.82
|
Signor
|
12607003
|
AMFR
|
ERLIN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
ERCC6
|
HMGCR
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.84
|
0.84
|
PKG
|
28854368
|
ATM
|
CREB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15073328
17209043
16293623
|
CREM
|
CREB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25609649
22531917
7809053
16189514
|
ERCC6
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
857.0
|
0.85
|
STRING
|
36370105
|
TP53
|
WRN
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
AUP1
|
SYVN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
31056421
21857022
22119785
28827405
|
XPA
|
ERCC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20541997
8999876
|
FOXO1
|
PRKACA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
MYC
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
21150319
16996503
19131971
|
HMGCR
|
INSIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
AMFR
|
INSIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ERCC6
|
ERCC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
8652557
16916636
16713569
16246722
|
MDC1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29656893
26734725
12607005
14519663
18006705
28943310
|
MYC
|
POLB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
XRCC4
|
NHEJ1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21070942
31548606
21768349
17567543
26774286
18064046
21349273
29997244
16439205
|
ATF6
|
SYVN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20160352
17967421
18664523
|
TP53
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9843217
9733515
9733514
|
FOXO3
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18344987
|
SREBF1
|
HMGCR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9651391
18413311
|
STAT5A
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
17927978
12048235
12967477
|
PPARA
|
SREBF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12730331
1273033
21540177
|
STAT5B
|
STAT5A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15043997
17997837
14532269
|
STAT5A
|
STAT5B
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21542777
15043997
17997837
|
TP53
|
SYVN1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16980608
|
TP53
|
WRN
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9774636
11427532
|
ATM
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
ATM
|
HMGCR
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-0.92
|
0.91
|
PKG
|
28854368
|
XRCC4
|
HMGCR
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.91
|
0.91
|
PKG
|
28854368
|
AMFR
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
UBC
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
MDC1
|
HMGCR
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.94
|
0.94
|
PKG
|
28854368
|
UBC
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.96
|
0.96
|
mint
|
17568776
5220017
|
NHEJ1
|
XRCC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
978.0
|
0.97
|
STRING
|
36370105
|
AMFR
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
CREBBP
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
CREB1
|
CREBBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
SYVN1
|
VCP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
RAD18
|
UBC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
WRN
|
POLB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
WRN
|
POLB
|
â—¼ SHARES_COMPLEX
|
|
|
65.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19364882
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
NHEJ1
|
XRCC4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
22228831
21349273
18064046
21070942
17567543
29997244
16439205
21768349
|
AMFR
|
VCP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
28.0
|
1.0
|
Omnipath
|
20126661
22328510
16407162
16987818
17681147
26712280
16275660
21636303
17872946
18835813
19828134
22119785
23333620
23383273
26424800
21343306
21914798
16186510
15331598
17311810
|
ATF6
|
SYVN1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
ACSN
|
17991856
18360008
23850759
26587781
|
WRN
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
ATM
|
MDC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
WRN
|
ATM
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
11283614
11331603
11850621
11877377
12202749
12607003
15140942
15211575
15385537
15459660
15498778
15964794
16163361
16449207
17055429
17116323
17303408
17965729
18087292
18171986
18398454
18524993
18558713
18584027
18809224
19202191
19362533
19490890
19654615
19772495
19793801
19892829
20027199
20064462
20691907
20713526
20723763
21376743
2191300
22657828
22743550
23082994
23161013
23253856
23847781
24036544
24050180
24089143
24095737
24709898
9721205
|
ATM
|
MDC1
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
MDC1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
MDC1
|
â—¼ REGULATES
|
✅
|
|
64.0
|
1.0
|
ACSN
|
11331603
11571274
11850621
11877377
12086603
12234250
12556884
12607003
14614141
14988723
15136767
15140942
15175241
15242590
15279786
15375219
15377654
15459660
15485915
15798197
15964794
16163361
16332722
16531125
16713580
16805667
16818604
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17660363
18001824
18006705
18087292
18469862
18543256
18583988
18584027
18590585
18678890
18809224
18995830
19151707
19282663
19342888
19622404
19686080
19772495
19793801
20051983
20160076
20723763
21376743
22743550
23030059
23847781
24050180
7575488
9407949
9488723
|
ATM
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
17.0
|
1.0
|
Omnipath
|
16293623
15073328
17525332
15212693
23642045
19115993
|
ATM
|
MDC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
28193847
21705321
22234877
12607003
12607005
22234878
17525332
18006705
|
ATM
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
452.0
|
1.0
|
Omnipath
|
25301947
21720806
23549171
10713094
16501611
15077171
24886358
17570479
19375142
22028490
16916644
14712210
19303885
9407038
11927276
26700820
28356518
15226429
10723129
19788889
12064478
19705844
26673821
22179422
20931131
19062161
27030982
22891162
17157788
19056039
15758953
12049739
15361830
26620371
25865756
22615843
10196661
10656682
11313957
25088203
15140942
12519769
16319535
24469230
12776195
17234789
27511909
29238697
24608431
12927814
16783362
11875057
16436515
22778557
15181149
12702572
10500142
15178764
28842590
28145533
11591448
17855337
22726545
20206688
26824362
21317290
26104798
24704793
9765199
11314044
16906133
17174997
21593792
17967874
10771484
15585169
19625493
15178448
17596534
16288207
15048074
18353733
24057508
19535302
29344296
23708100
29872395
23705030
25043304
33761896
18431490
21404020
15024084
22559321
12151394
24078877
12080066
33982778
16893723
10958792
18289945
27183917
26337656
29170437
18765533
10744722
21748595
18056442
24820418
15489892
16390936
24086335
28140789
23091651
34523970
32001619
23418564
15279808
21317932
21188172
27559048
16818505
17616578
11551930
19010925
11709713
24711418
28654064
18339864
11173129
17486112
10570149
29774100
18381438
21994612
29558908
15258567
9372954
25860929
16858402
33692124
15775976
34107253
19923893
24958101
10436023
14752509
19962312
19071090
26438152
26093282
20123963
22444248
9843217
17525332
15456784
23533526
11780126
20353948
29290977
11096068
28102346
18855897
20372057
24395704
23890999
15725625
15806145
34103468
18345031
16997395
16293623
28477117
19828454
27630139
12071847
22002314
21315088
27177180
12645530
12890678
26113041
15794754
18560558
22099307
9885574
28903382
15665826
24877058
18332866
10611322
24380814
14871840
19934315
22975381
16489034
18406507
21440540
33687951
10608806
23892398
20730097
16914171
15782130
15177184
22055193
18490454
25867001
24349352
18045533
20663147
17535811
20506250
23982736
22375140
15700044
15279774
19266268
24358288
18697815
14729946
20637859
12242661
12771937
17371838
31940492
19409520
10528155
24037342
17257427
11121242
15310764
23148227
28915641
26928575
21423215
11865061
16949371
27810895
18449195
20711232
27389279
22213803
16713569
10446957
22797063
16478990
29048667
15489221
17241873
21187893
21441950
23907539
20005840
9733514
26244501
21614094
12082529
10467728
10714958
32061892
16636671
29147215
10673501
12091386
25202122
21465263
19544417
25823026
24078903
24038750
22198295
21480565
15177039
28182994
28208785
18674635
20183804
18818083
9925639
17712528
15254178
11483158
27940348
26675349
26261212
19717643
12606585
24559687
14871926
23150668
21329876
28153791
12518062
12767922
23824039
11711532
19251701
28118604
15078887
12393500
17456577
20976220
23380594
12519780
20810927
15533933
22420423
17108107
20145032
18032786
18785202
22037398
23184057
31968249
16729035
12588868
21614932
11546806
18614045
14757188
15029243
14968111
22649771
25512053
34496248
18604166
17609585
17976513
16223874
25433195
18985806
9363941
15159397
34282274
29301278
24505404
26056062
23577291
18272544
18715874
19536869
29334356
10801407
15155458
25201202
24376853
19907922
23525106
14643431
28340339
28051100
19085961
15212693
22201816
20026654
16322229
20080565
9733515
15632067
18672098
22577550
25691451
12637545
12548019
11672523
26984736
12324477
16552184
22084686
10864201
14744854
21532626
17118344
19482562
9561848
12511424
17668048
23358251
18511169
21460853
22022355
12939400
21415014
17292432
25651062
23168260
12111733
16648554
30361254
23678107
|
CREB1
|
PRKACA
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
7.0
|
1.0
|
Reactome
|
19244110
12150772
12082174
2573431
9733829
17908236
15879576
|
CREM
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
22531917
16189514
7809053
1847666
|
PRKACA
|
CREB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
11175347
12356771
15733869
11160957
21902831
2885756
2875459
7958915
9829964
12235136
12763014
9687510
8887554
15568017
11698596
8688081
9528766
11018520
11969286
11909979
8336722
|
CREB1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16611888
25241761
21295542
|
CREB1
|
CREBBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
47.0
|
1.0
|
Omnipath
|
10866654
18599546
15585582
7870178
8028671
11313407
16007092
8413673
11564156
15691881
9829964
15073328
20403362
11259575
17476304
17707401
20541704
16799563
7870179
11123304
27789289
7913207
12933667
8663317
8004670
11483993
12198160
9413984
|
TP53
|
CREBBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
19057620
15632413
11466559
19448667
19880525
9891054
22198284
10833421
11709699
10435630
11390631
9890939
21191649
12501250
11928223
17434128
12164786
24330748
11779500
10435595
21513889
10777477
|
CREBBP
|
SREBF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
9651391
16799563
10235267
9765204
8918891
|
CREBBP
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
17303408
15522869
12776737
20144767
17660363
16878156
15279786
|
CREBBP
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
49.0
|
1.0
|
Omnipath
|
17303408
25545885
27618436
19220000
16713569
10823891
15632413
19805293
25451029
15279786
10473588
12154097
7575488
16537920
10848610
18485870
19880525
10648616
20144767
14722092
14759370
18590585
26976603
9194564
19788416
25314079
19166313
12426395
9288775
11782467
17660363
19234109
21390126
10196247
17434128
19357310
10551785
22084066
|
XPA
|
DDB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
11278856
23038248
18614043
25154395
14517266
19056823
20368362
|
TP53
|
DDB2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
12771027
22336944
15856024
12509284
12170778
16357511
12967652
15927209
11971958
|
ERCC6
|
ERCC5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
16916636
8652557
16713569
16246722
|
ERCC6
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
16713569
10882116
19221478
18784753
|
FOXO3
|
FOXO1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19244250
16100571
18202312
23509296
19690465
|
FOXO1
|
SREBF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
24478438
16492665
18202130
20868688
22511764
|
PPARA
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16985262
18391971
|
SREBF2
|
HMGCR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
19288057
21944868
20936497
17448444
31848472
18413311
|
PRKACA
|
HMGCR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
2369897
|
MYC
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10962037
10656696
8494784
10348347
19882681
16557594
19086036
15780936
14519204
16112647
11781835
7969121
11789587
9839551
|
PRKACA
|
SREBF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
16381800
|
SREBF1
|
SREBF2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
14702347
16282353
9786926
11278785
|
WRN
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12080066
11399766
15735006
16713569
11427532
|
TP53
|
WRN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
12080066
11399766
15735006
16713569
11427532
|
POLB
|
HMGCR
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.04
|
1.04
|
PKG
|
28854368
|
WRN
|
HMGCR
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.18
|
1.18
|
PKG
|
28854368
|
ERCC6
|
ERCC6
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.24
|
1.23
|
PKG
|
28854368
|
XPA
|
HMGCR
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.28
|
1.27
|
PKG
|
28854368
|
ERCC5
|
HMGCR
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.4
|
1.39
|
PKG
|
28854368
|
NHEJ1
|
HMGCR
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.54
|
1.54
|
PKG
|
28854368
|
DDB2
|
HMGCR
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.56
|
1.55
|
PKG
|
28854368
|
ERCC5
|
ERCC5
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.7
|
1.69
|
PKG
|
28854368
|
ATM
|
ATM
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-2.25
|
2.25
|
PKG
|
28854368
|
MDC1
|
MDC1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.38
|
3.37
|
PKG
|
28854368
|
TP53
|
DDB2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.51
|
3.5
|
PKG
|
28854368
|
WRN
|
WRN
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-3.6
|
3.59
|
PKG
|
28854368
|
RAD18
|
RAD18
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-4.39
|
4.38
|
PKG
|
28854368
|
RAD18
|
HMGCR
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-4.61
|
4.6
|
PKG
|
28854368
|
DDB2
|
DDB2
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-5.71
|
5.7
|
PKG
|
28854368
|
XRCC4
|
XRCC4
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-6.32
|
6.31
|
PKG
|
28854368
|
NHEJ1
|
NHEJ1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-6.47
|
6.46
|
PKG
|
28854368
|
POLB
|
POLB
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-7.24
|
7.23
|
PKG
|
28854368
|