Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SREBF1 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
RNF139 ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ATXN1 SREBF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SREBF2 INSIG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15073165
RNF139 INSIG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20068067
SREBF1 INSIG1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15073165
SCAP SREBF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12202038 12242332
SCAP SREBF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10896675 12202038
SCAP SREBF2 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
SCAP SREBF1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
INSIG1 SCAP â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HMGCR INSIG1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AUP1 UBE2G2 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ERLIN1 ERLIN2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
SCAP SREBF2 â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 12202038
SREBF1 HMGCR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9651391 18413311
INSIG2 SCAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 12482938 12242332 34192549 16549805
SREBF2 HMGCR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19288057 21944868 20936497 17448444 31848472 18413311
INSIG1 SCAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12202038 12482938 23564452 12842885 32111832 26555173 32432943
SREBF1 SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14702347 16282353 9786926 11278785