Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PARP1 DDB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
DCLRE1A ERVH48-1 â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
PARP1 ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
PARP1 DDB2 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
POLB ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
POLM ERVH48-1 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
CBX1 ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
PARP1 POLB â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10858306 11163244 11283614 11756412 11948190 12032095 12202749 12637553 14624239 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18087292 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 1974050 19748837 19772495 19847258 20027199 20064462 20211143 20227374 20478261 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22021614 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23414611 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 POLB â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10858306 11163244 11283614 11756412 11948190 12032095 12202749 12637553 14624239 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18087292 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 1974050 19748837 19772495 19847258 20027199 20064462 20211143 20227374 20478261 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22021614 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23414611 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
NHEJ1 POLM â—¼   PHYSICAL_INTERACTION 13.0 1.0 Reactome 16439204 17470781 22529269 15451442 14561766 12077346 10757784 9259561 16439205 11702069 18046455 9430729 12509254
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
TP53 ERVH48-1 â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
EXO1 ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -1.13 1.12 PKG 28854368
MDC1 ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -1.14 1.13 PKG 28854368
FANCM ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
NHEJ1 ERVH48-1 â—¼   KO_DOWN_REGULATES ✅ - -1.19 1.18 PKG 28854368
ERCC5 ERVH48-1 â—¼   KO_UP_REGULATES ✅ + 1.3 1.3 PKG 28854368
DDB2 ERVH48-1 â—¼   KO_UP_REGULATES ✅ + 1.33 1.33 PKG 28854368
EXO5 ERVH48-1 â—¼   KO_UP_REGULATES ✅ + 1.4 1.4 PKG 28854368
ERCC5 ERCC5 â—¼   KO_DOWN_REGULATES ✅ - -1.7 1.69 PKG 28854368
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368