Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F1 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19376752
ERCC5 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8652557
CCNH TCEA1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CDK7 T2EA â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25492609 29568061 15282296 23064645
LZTS2 ERCC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ERCC5 TF2H2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 8652557
LZTS2 TF2H1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MAT1 TF2H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 33961781
CCNH ERCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ERCC2 T2EA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25492609 27193682
FGL1 ERCC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
FGL1 TF2H1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TF2H5 TF2H1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19172752 26496610 33961781 24981860
TF2H5 TF2H3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19172752 26496610 33961781 24981860
T2H2L TF2H5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
FGL1 TF2H2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
T2H2L CDK7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
TF2H1 RPB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10454562 32355176 8934526 34108663 15282296
CDK7 E2F1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10428966 23397142 20106982
ERCC2 RPB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27193682 32355176
ANDR TF2H1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11266437 10734072 16713569
ESR1 CCNH â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12527756 31527615
ESR1 RPB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 20308691 16957778 31527615 20348541
TF2H5 CCNH â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33707221 26496610 26340423
CCNH TF2H4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19172752 22939629 33707221 26340423
TCEA1 CDK7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26186194 9305922
T2H2L ERCC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 26186194 26344197
T2EA ERCC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25492609 8152490 7926747
TF2H1 ERCC5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16713569 11259578 33961781 8652557 15195146
T2H2L TF2H1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26340423 33961781 24981860 26186194 26344197
TCEA1 T2EA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10454562 9305922
T2H2L TF2H4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24981860 33961781 26186194 26344197
ERCC3 TCEA1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK7 E2F1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDK7 TCEA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CDK7 ESR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15461668 10949034 31527615
TF2H1 E2F1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9400991 10428966
P53 ERCC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8612585 16189514 16713569 7663514
TF2H1 MAT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22939629 33961781 26340423 9852112
TCEA1 TF2H1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9765293 10454562 9305922
TF2H4 T2EA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11113176 9159119
RPB1 T2EA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 7926747 9159119
ANDR CDK7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10734072 21157430
CDK7 ERCC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17643375 33961781 23602568 32707033 29568061
CDK7 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 9315650 9372954 9840937
CDK7 TF2H4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17643375 33961781 23602568 32707033 29568061
P53 E2F1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8557038 11739724 24076372
TF2H5 ERCC2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19172752 27193682 26496610
XPC ERCC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26278177 10734143
P53 ERCC3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 7663514 12379483 8612585 32807901
ERCC3 ERCC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 8652557 17643375
TF2H1 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10949034 31527615
P53 ESR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 26556313 10766163 17545634 21761334
TF2H1 TF2H4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 26340423 19172752 33961781 24981860 22939629 26344197
TF2H5 TF2H4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 19172752 26496610 33961781 24981860 26340423
TF2H2 TF2H4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19172752 11062469 26344197 33961781 24981860 19934020 28977422 22939629 26340423
TF2H5 TF2H2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 19172752 11062469 26496610 15220921 33961781 24981860 16669699
TF2H3 T2H2L â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 25416956 24981860 33961781 26186194 26344197
ERCC2 TCEA1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CCNH TF2H1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9852112 33707221 11259578 7533895 26340423 10734143
CCNH ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 33707221 17643375 15220921 33453189 8692842 33961781 26186194 19934020 9118947 26340423 10734143
TF2H5 CDK7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26496610 15220921 23602568 32707033 29568061
CDK7 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 8692841 17643375 15220921 8521393 33453189 33961781 10082552 9130708 23602568 28977422 32707033 29568061 26340423
CDK7 TF2H1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8692841 9852112 8521393 7533895 9130708 23602568 28977422 32707033 29568061 26340423
ERCC5 ERCC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 32245994 8652557 16713569
TF2H1 ERCC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8652557 9130708 8152490 11071939 26340423
TF2H1 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9173976 26340423 17643375 8194528 15220921 11259578 33453189 8692842 8652557 19934020 9130708 9118947 33961781 24981860 22939629 10403766 26344197
MAT1 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 17643375 15220921 33453189 8692842 33961781 9118947 26340423
TF2H2 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 26340423 17643375 15220921 8194529 33453189 33961781 8652557 19934020 28977422 9118947 10924514 24981860 26344197
TF2H5 ERCC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19172752 26496610 15220921 33961781 24981860 16669699 26340423
XPC TF2H1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26278177 11259578 10734143
MAT1 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8308015 10949034 12527756 31527615
MAT1 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30477538 16189514 9372954 16713569
P53 TF2H1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16793543 16713569 18160537 7935417 18354501 8612585
TF2H4 ERCC2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 19172752 27193682
ERCC2 TF2H3 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 27193682 8652557 21157430
RPB1 CDK7 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22379099 32355176 9311822 15009212 15328539 20106982 23064645 8692842 15282296 16327805 18391197 11278802 15530371
TF2H3 TF2H1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 21157430 26340423 8194529 33961781 24981860 22939629 12080057 26344197
TF2H3 TF2H4 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 26340423 33961781 24981860 22939629 12080057 26344197
ERCC5 ERCC2 â—¼   PHYSICAL_INTERACTION ✅ + 0.95 0.95 Signor 20840796
TF2H2 CCNH â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 33707221 11062469 19934020 10924514 26340423
CCNH ERCC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 33707221 8692842 33961781 26186194 22939629 26340423
CDK7 TF2H3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 21157430 17643375 28977422 23602568 32707033 29568061
CDK7 ERCC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 8692841 33961781 26186194 11445587 23602568 32707033 22939629 29568061
TF2H1 TF2H2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 21988832 26340423 11062469 8194529 33961781 8652557 19934020 9130708 28977422 10924514 24981860 26344197
CDK7 CCNH â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9334327 15698475 11113184 15328539 33707221 17643375 8078587 26340423 33476598 8521818 8521393 23602568 29568061 33453189 32707033 22939629 11713533 10958691 8692841 16782892 9218599 33961781 10082552 26186194 9056480 26344197
CCNH MAT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16782892 26340423 17353931 33476598 15328539 33707221 8521818 33961781 12527756 26186194 22939629 26344197
CDK7 MAT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 9334327 26340423 17643375 8521818 8521393 10801852 33961781 10082552 12527756 9130708 23602568 26186194 32707033 22939629 33453189 29568061 26344197
CDK7 TF2H2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17643375 11062469 23602568 19934020 28977422 9130708 10924514 29568061
TF2H2 ERCC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 11062469 8652557 9771713 19934020 10924514 27193682 12820975 26340423
ERCC3 ERCC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15220921 9118947 8652557 19934020 16669699 33381997 8152490 22939629 22678362 26340423 27193682
TF2H4 ERCC3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19172752 15220921 26344197 33961781 24981860 33453189 9118947 22939629 26340423
TF2H3 ERCC3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 26340423 17643375 15220921 8194529 33453189 33961781 8652557 24981860 9118947 22939629 26344197
TF2H1 T2EA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 32296183 25492609 18160537 18354501 11113176
RPB1 TCEA1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 9305922 23748380 9765293 20178742 17643375 20562857 16916636 22939629 12914699
TF2H3 TF2H2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 21157430 26340423 15790571 33961781 8652557 24981860 28977422 22939629 12080057 26344197
ERCC2 MAT1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 10801852 33961781 26186194 22939629 32245994 26340423
CDK7 ERCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCNH ERCC3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH ERCC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH CDK7 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CCNH CDK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23602568 11113184 8521818 16782892 15698475 15328539 19153657 10082552 26340423 8692841 26186194 9334327 10958691 10734072 9056480 9218599 8078587 8521393 17643375
CDK7 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CDK7 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23397142 10428966 17050006
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
ERCC2 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
ERCC5 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8652557 16713569 20840796
ERCC2 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10734072 8652557 10024882 16669699