Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F1 XPC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19376752
ERCC5 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8652557
CCNH TCEA1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CDK7 T2EA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29568061 25492609 15282296 23064645
MAT1 TF2H4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22939629
LZTS2 TF2H1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ERCC5 TF2H2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 8652557 33961781
LZTS2 ERCC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TF2H5 TF2H1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26496610 19172752 28514442
FGL1 TF2H1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
T2H2L TF2H5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
TF2H5 TF2H3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 26496610 19172752 28514442
FGL1 TF2H2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ERCC2 T2EA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25492609 27193682
FGL1 ERCC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TF2H1 RPB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32355176 8934526 34108663 15282296 10454562
T2H2L CDK7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
ANDR TF2H1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10734072 11266437 16713569
ERCC2 RPB1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32355176 27193682
ESR1 RPB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20308691 31527615 16957778 20348541
ESR1 CCNH â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12527756 31527615
T2H2L TF2H1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26344197 26340423 26186194 28514442
TF2H1 ERCC5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 15195146 16713569 8652557 11259578
CCNH TF2H4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19172752 33707221 22939629 26340423
T2H2L TF2H4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26344197 26186194 28514442
TF2H5 CCNH â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33707221 26340423 26496610
T2EA ERCC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8152490 25492609 7926747
TCEA1 T2EA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10454562 9305922
T2H2L ERCC3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 26344197 26186194 28514442
TCEA1 CDK7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26186194 9305922
ERCC3 TCEA1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK7 E2F1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CDK7 TCEA1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
P53 ERCC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7663514 16713569 8612585 16189514
TF2H1 MAT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 9852112 22939629 26340423
TCEA1 TF2H1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10454562 9765293 9305922
TF2H1 E2F1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9400991 10428966
TF2H4 T2EA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9159119 11113176
RPB1 T2EA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 7926747 9159119
CDK7 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10949034 31527615 15461668
ANDR CDK7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21157430 10734072
CDK7 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9315650 9840937 32707033 9372954
P53 ERCC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 12379483 16713569 8612585 7663514 32807901
P53 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17545634 26556313 10766163 16713569 21761334
P53 E2F1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24076372 11739724 8557038
TF2H1 TF2H4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 26344197 22939629 26340423 19172752
TF2H1 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10949034 31527615
TF2H5 TF2H4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 32296183 24981860 26340423 26496610 19172752 28514442
TF2H2 TF2H4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 26344197 26340423 11062469 22939629 19172752 28977422 19934020
CDK7 TF2H4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17643375 33961781 29568061 23602568 32707033
TF2H5 ERCC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19172752 26496610 27193682
TF2H5 TF2H2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15220921 33961781 24981860 16669699 11062469 26496610 19172752 28514442
TF2H3 T2H2L â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 26344197 25416956 26186194 28514442
CDK7 ERCC5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17643375 33961781 29568061 23602568 32707033
XPC ERCC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26278177 10734143
ERCC2 TCEA1 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
MAT1 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30477538 9372954 16713569 16189514
P53 TF2H1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18160537 16793543 16713569 7935417 8612585 18354501
MAT1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12527756 10949034 8308015 31527615
MAT1 ERCC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15220921 17643375 33961781 26340423 33453189 8692842 28514442 9118947 16189514
CDK7 TF2H1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9130708 8521393 9852112 26340423 7533895 29568061 23602568 28977422 32707033 8692841
CCNH TF2H1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9852112 26340423 7533895 10734143 33707221 11259578
TF2H1 ERCC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9130708 26340423 8152490 11071939 8652557
XPC TF2H1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26278177 10734143 11259578
TF2H1 ERCC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15220921 17643375 33961781 9130708 24981860 9173976 26344197 22939629 26340423 33453189 19934020 8194528 10403766 8692842 8652557 28514442 9118947 11259578
TF2H5 CDK7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15220921 26496610 29568061 23602568 32707033
TF2H5 ERCC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15220921 33961781 24981860 16669699 26340423 26496610 19172752 28514442
TF2H2 ERCC3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15220921 17643375 33961781 24981860 26344197 10924514 26340423 8194529 33453189 28977422 8652557 28514442 9118947 16189514 19934020
ERCC5 ERCC2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8652557 16189514 16713569 32245994
TF2H4 ERCC2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 19172752 27193682
ERCC2 TF2H3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 8652557 21157430 27193682
TF2H3 TF2H1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 24981860 26344197 22939629 8194529 26340423 21157430 28514442 12080057
TF2H3 TF2H4 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 24981860 26344197 22939629 26340423 28514442 12080057
RPB1 CDK7 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 11278802 32355176 22379099 15282296 23064645 18391197 9311822 15328539 15009212 8692842 20106982 16327805 15530371
TF2H1 TF2H2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 9130708 24981860 26344197 10924514 11062469 8194529 26340423 21988832 8652557 28977422 19934020
TF2H2 CCNH â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 10924514 11062469 26340423 33707221 19934020
CDK7 TF2H3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 17643375 21157430 29568061 23602568 28977422 32707033
CDK7 MAT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 17643375 33961781 9130708 26344197 8521393 8521818 22939629 26340423 12527756 33453189 10082552 26186194 9334327 10801852 29568061 28514442 23602568 32707033
CCNH MAT1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 26344197 17353931 8521818 22939629 16782892 26340423 33476598 12527756 26186194 33707221 15328539 28514442
TF2H1 T2EA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 18160537 32296183 25492609 11113176 18354501
TF2H4 ERCC3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15220921 33961781 24981860 26344197 22939629 26340423 33453189 19172752 28514442 9118947
RPB1 TCEA1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 17643375 16916636 22939629 9765293 20562857 20178742 23748380 9305922 12914699
TF2H2 ERCC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 9771713 27193682 10924514 11062469 26340423 8652557 12820975 16189514 19934020
CDK7 TF2H2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 17643375 9130708 10924514 11062469 29568061 23602568 28977422 19934020
TF2H3 TF2H2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 15790571 26344197 24981860 22939629 26340423 21157430 8652557 28514442 28977422 12080057
TF2H3 ERCC3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15220921 17643375 33961781 24981860 26344197 22939629 8194529 26340423 33453189 8652557 28514442 9118947
CDK7 CCNH â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 22939629 16782892 26340423 9218599 15698475 23602568 17643375 26344197 33453189 10082552 33707221 15328539 32707033 8692841 33476598 9334327 28514442 9056480 8078587 10958691 11713533 8521393 8521818 11113184 26186194 29568061
ERCC3 ERCC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15220921 27193682 16669699 33381997 22939629 26340423 8152490 8652557 9118947 22678362 19934020
ERCC2 MAT1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 26340423 32245994 26186194 10801852 28514442
CDK7 ERCC2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CCNH ERCC3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH ERCC2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNH CDK7 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDK7 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
ERCC2 ERCC3 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNH CDK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23602568 11113184 8521818 16782892 15698475 15328539 19153657 10082552 26340423 8692841 26186194 9334327 10958691 10734072 9056480 9218599 8078587 8521393 17643375
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
CDK7 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 23397142 10428966 17050006
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
ERCC5 ERCC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8652557 16713569 20840796
ERCC2 ERCC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10734072 8652557 10024882 16669699
ERCC5 ERCC5 â—¼   KO_DOWN_REGULATES ✅ - -1.7 1.69 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368