Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RECQL4 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19567405
NHEJ1 XRCC4 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
HNRNPC ACAD10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
APLNR NDRG4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
ATM WRN â—¼   PHOSPHORYLATION 0.8 0.8 Signor 10608806
ATM EXO1 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 20019063
NPY2R ATM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LPAR4 ATM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
P2RY8 ATM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NDRG2 NDRG1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SETX ACAD10 â—¼   KO_UP_REGULATES ✅ + 0.84 0.84 PKG 28854368
ACAD10 ACOXL â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
ACAD10 AIFM3 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
ACAD10 ACOX3 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
ACAD10 AIFM2 â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
POLB RHPN2 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
XRCC4 ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -0.89 0.88 PKG 28854368
ERCC5 ACAD10 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
XRCC4 NHEJ1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21070942 31548606 21768349 17567543 26774286 18064046 21349273 29997244 16439205
RECQL4 ACAD10 â—¼   KO_UP_REGULATES ✅ + 0.93 0.93 PKG 28854368
ACAD10 RMDN1 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
NHEJ1 XRCC4 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
EXO1 ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
POLB ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
WRN ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -1.0 0.99 PKG 28854368
WRN POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
WRN POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
NHEJ1 XRCC4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 22228831 21349273 18064046 21070942 17567543 29997244 16439205 21768349
WRN ATM â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
WRN ATM â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 11283614 11331603 11850621 11877377 12202749 12607003 15140942 15211575 15385537 15459660 15498778 15964794 16163361 16449207 17055429 17116323 17303408 17965729 18087292 18171986 18398454 18524993 18558713 18584027 18809224 19202191 19362533 19490890 19654615 19772495 19793801 19892829 20027199 20064462 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 9721205
ATM EXO1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM EXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 15964794 11877377 17303408 18756267 16163361 15867354 23847781 23675572 25956864 26240375 11438669 24705021 12607003 18048416 17525332 20019063 15459660
ATM ACAD10 â—¼   KO_UP_REGULATES ✅ + 1.14 1.14 PKG 28854368
NHEJ1 ACAD10 â—¼   KO_DOWN_REGULATES ✅ - -1.18 1.17 PKG 28854368
DDB2 ACAD10 â—¼   KO_UP_REGULATES ✅ + 1.36 1.36 PKG 28854368
ERCC5 ERCC5 â—¼   KO_DOWN_REGULATES ✅ - -1.7 1.69 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
RECQL4 RECQL4 â—¼   KO_DOWN_REGULATES ✅ - -2.61 2.61 PKG 28854368
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
SETX SETX â—¼   KO_DOWN_REGULATES ✅ - -8.56 8.55 PKG 28854368