Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PCNA ALDOA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7995081 20849852
PCNA ALDOA â—¼   COLOCALIZATION 2.0 0.8 intact 7995081 20849852
IRF1 PCNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19129219
IRF3 ISG15 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12354379
ARG1 FLOT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219356 17113085
PCLO FLOT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYH15 FLOT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FLOT1 RIPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
FLOT1 GOLM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
FLOT1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
FLOT1 MLKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
H3C2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CANX ABCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 583591 25170080
ABCA1 CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 583591 25170080
ABCA1 FLNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 583591 25170080
ELF4 ALDOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15226428 10801845
HTT APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CAV1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COX5B ATP2B4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
BMI1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6948569 19233177
CFTR CANX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12208510 5215704
CAPN10 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HRAS CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8621645 5220985
PTPN1 CAV1 â—¼   COLOCALIZATION 2.0 0.8 intact 12176037 6731969
YES1 CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8981370 20489731
HTT CBL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CHMP4B HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBC COPS5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7229502 19214193
DBN1 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HTT DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FLNA RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
RIPK1 FLOT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
FLOT2 RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
FLOT2 MLKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 31138766 24316671
FN1 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 16005629 16115959
HDAC6 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMD4 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STAT5A IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9341115 9806359
STAT5A PTPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12237455 6671710
SLC4A1 PTPN1 â—¼   COLOCALIZATION 2.0 0.8 intact 6731946 8615784
PTPN1 STAT5A â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 12237455 6671710
VIM RIPK3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
WWP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
DDB2 FLOT1 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
DOT1L UBC â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ISG15 IRF3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32726803 20308324
HD FLOT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32814053 25959826
MMGT1 FLOT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 27342126
PKHA7 FLOT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28877994 34079125
ZDHC5 FLOT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31402609 34079125
CCDC8 FLOT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 24711643
CHM4B FLOT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
FLOT1 YES â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 22936677
FLOT1 VAMP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 34079125
FLOT1 OCAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32877691 22939629
FLOT1 S38A2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 34079125
FLOT1 CDCA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
FLOT1 PICAL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 34079125
VCAM1 PICAL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
RAB7A CHM4B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
FLNA CHM4B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
CHM4B FLOT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
VCAM1 CHM4B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
PKHA7 LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 28877994
VAPA OCAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34133714 34079125
VCAM1 ALDOA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
BMI1 LIMA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
MMGT1 CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 27342126
RAB2A CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 34079125
CFTR CAV1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
CCDC8 RAB5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 24711643
VCAM1 FLNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
SOX2 MYEF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23667531 21532573
VCAM1 MYH9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VAPA RAB5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
VCAM1 RAB5C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 RAC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 VAPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
DDB2 FLOT2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
BBS1 BBS2 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
FLOT1 SVIL â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
NGB FLOT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15120622 15939299 16189514
CFTR SVIL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
CFTR FLOT2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29924966 17110338
UBC HGS â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12750381 5216384
SOX5 SOX6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 9755172 33961781
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CFTR ALDOA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
CFTR LIMA1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
CFTR MYH9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 22038833
UBC PSMD4 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5220924 8570649
FLOT1 RAB5C â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
SVIL LIMA1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 20309963
SVIL FLNA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 20309963
RAB5C OCAD1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
RAB5C CAV1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
RAB7A CAV1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
FLNA MYH9 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
RAB5C FLOT2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
FLOT2 RAB2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22939629 26496610
PCNA UBC â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
FRS2 FLOT1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22235335 34079125
HD ALDOA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32814053 25959826 17500595
FLOT2 MMGT1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22939629 26496610 27342126
PARK2 PSMD4 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
NHEJ1 FLOT1 â—¼   KO_DOWN_REGULATES ✅ - -0.88 0.87 PKG 28854368
BBS1 BBS7 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
ATP6AP2 ATP6V1A â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SRBS1 CBL â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11001060 15128873 17548467 12504111
APP BACE1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BBS4 BBS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27173435 17574030 19081074 28514442 22500027
RAB7A RAB5C â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26344197 34079125
VAPA VAMP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9657962 22939629 16189514
BBS7 BBS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27173435 29039417 17574030 20080638 28514442 22500027
BBS4 BBS2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27173435 22139371 17574030 25552655 19081074 22500027
CAV1 FLOT2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10212252 16189514 34079125
FRS2 CBL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17944804 20038681 11997436
CBL UBC â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
IRF8 IRF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11483597 7768900 9742224
RAB7A RAB2A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26496610 26344197 34079125
FLOT1 FLOT2 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
COPS5 DDB2 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CBL SORBS1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
SRPK1 U2AF2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
CAV1 FLOT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22936677 10212252 25204797 34079125
FLOT1 SRBS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11001060 11481476 15128873 17548467 15939299
BBS2 BBS7 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
ETV4 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15138262 19483189 17390339
ETV4 VIM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8895512 9769935
STAT4 IRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10068671 10037767 10358173
RIPK3 RIPK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19524513 30420664 29497034 22864571 26786097 31358971 22817896 23744296 26559832 19524512 26319693 22265414 22265413 29352166 29883609 21903422 24098568 25882049 10339433
STAT5B STAT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15043997 17997837 14532269
STAT5A STAT5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21542777 15043997 17997837
BBS4 BBS7 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
FLOT1 FLOT2 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
MLKL RIPK3 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
BBS2 BBS4 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
COX5B CYC1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
KIAA0368 PSMD4 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
ATP6V1A ATP6V1B1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
FLOT2 SVIL â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
HGS UBC â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
HDAC6 UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BBS1 BBS4 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
PARK2 UBC â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMD4 UBC â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
IRF3 ISG15 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19367472 8524823 12604599 9446577
AURKB HASPIN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21658950 18669648
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
BACE1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 30538620 22801501 10677483 20418918 12901838 10531052 10931940 32814053 28923680 28869759 19251705
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB VIM â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 14762106 14722118 11895474 17081983 19007248 11420699 15676024 12458200 18669648
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
PTPN1 CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 16388599 12176037 16189514
CAV1 PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 18988627 16189514 10066366
HGS CBL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
FRS2 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 20038681 11997436
YES1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10092522 11994282 11997497 12522270 9525940 12604776 9890970 9102067 10829062 10799548 11239464 10934191
SORBS1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15128873 9447983 17548467 12504111 12765336 11001060
CBL PDGFRA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 9234717 10347229 18988627 17635922 10514377
CBL SORBS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12475393 15128873 20886612
ETV6 STAT5A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 31066629 17764812 19345670 23168613
ETV6 STAT5B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 31066629 17764812 19345670 23168613
KRAS FRS2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
HRAS FRS2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
NRAS FRS2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 Reactome 19946327 11429702 11157491 18757403 21666749 21711248 18381441 19103595 21160078 9857065 20179196
IRF1 IRF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 7768900 10570299 9742224 11483597
RIPK1 MLKL â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18641653 19037093 19498109 19524512 19524513 19597341 19632174 19838173 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866
RIPK3 MLKL â—¼   PHYSICAL_INTERACTION 55.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18641653 19037093 19090789 19498109 19524512 19524513 19597341 19632174 19838173 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9242610 9488730 9759866
RIPK3 MLKL â—¼   SHARES_COMPLEX 55.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18641653 19037093 19090789 19498109 19524512 19524513 19597341 19632174 19838173 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9242610 9488730 9759866
RIPK1 MLKL â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18641653 19037093 19498109 19524512 19524513 19597341 19632174 19838173 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866
RIPK1 MLKL â—¼   ENZYMATIC_REACTION ✅ 53.0 1.0 ACSN 11003656 11274345 1134007 11583996 12215447 12702723 12724420 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18641653 19037093 19498109 19524512 19524513 19597341 19632174 19838173 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866
RIPK3 MLKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 27826146 24434512 25493335 26024392 28126382 26866270 34155344 27959630 24901049 27832137 26184911 30029665 26967968 29026104 24703947 28807105 27941671 23612963 24012422 29484439 22265413
PTPN1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10993888 12237455
PTPN1 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10993888 12237455
RIPK1 RIPK3 â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 10521396 11003656 11274345 1134007 11583996 12215447 12702723 12724420 12887920 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18570872 18621737 18641653 19037093 19131965 19498109 19524512 19524513 19597341 19632174 19838173 19935698 20125124 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866
RIPK1 RIPK3 â—¼   SHARES_COMPLEX 60.0 1.0 ACSN 10521396 11003656 11274345 1134007 11583996 12215447 12702723 12724420 12887920 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18570872 18621737 18641653 19037093 19131965 19498109 19524512 19524513 19597341 19632174 19838173 19935698 20125124 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866
RIPK1 RIPK3 â—¼   ENZYMATIC_REACTION ✅ 60.0 1.0 ACSN 10521396 11003656 11274345 1134007 11583996 12215447 12702723 12724420 12887920 15592525 15760909 16469705 16498403 16940415 17462996 17603935 18570872 18621737 18641653 19037093 19131965 19498109 19524512 19524513 19597341 19632174 19838173 19935698 20125124 20531300 20823910 20861672 21133840 21232017 22265414 22421439 22427918 23010170 23069999 23073834 23377657 23627914 24366341 26024392 26587781 26653790 26807733 26853145 26900751 26972597 27558815 27833036 27959630 27984721 28498367 28574505 28645028 9217161 9488730 9759866
RIPK3 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 11734559 21903422 22265414 19524512 19524513 22817896 26559832 10339433 26319693 11585904 22265413
NHEJ1 PCNA â—¼   KO_DOWN_REGULATES ✅ - -1.66 1.65 PKG 28854368
NHEJ1 VIM â—¼   KO_UP_REGULATES ✅ + 1.75 1.75 PKG 28854368
DDB2 CAV1 â—¼   KO_DOWN_REGULATES ✅ - -2.05 2.04 PKG 28854368
DDB2 VIM â—¼   KO_DOWN_REGULATES ✅ - -2.33 2.32 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368