Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
COPA IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
DNAJB1 DNAJC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 9920933
EGFR ANXA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217387 15581623
EGFR ANXA1 â—¼   COLOCALIZATION 2.0 0.8 intact 5217387 15581623
MATR3 FLII â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
FXR2 PAICS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 NASP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 FBP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FXR2 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 BCKDK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 IMPDH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR2 DNM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
GORASP2 NUP62 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MSH2 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CCAR1 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CAD IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HNRNPU IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MYO6 IKBKG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSP90B1 LIG3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HIF1A LRP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 21454812
HSP90B1 LRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11861214 11290339
HGF MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16397249 17667909
MAPK1 GABPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19114066
FUS MATR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27731383
NUP62 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18292223 0712387105
HDAC1 CTNNB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19166851 6823802
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
CUL1 ARIH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24076655
EIF2B1 EIF2S1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8887689 15054402
EIF2B1 EIF2S2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15054402 9446619
EIF2S1 EIF4G2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16932749 5219000
HIF1A BSG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19828020 22678117
LIMK1 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133759 0914492107
CFL1 LIMK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6173882 17853892
CTNNB1 GAPDH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CFL1 EIF3D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EIF3E GPAA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
NCL NAT10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NUP98 HNRNPUL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19745842 7293793
LUC7L2 ALB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CPSF6 EWSR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
LUC7L2 NASP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
EGFR JUP â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
NEMF NOP56 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
EIF2S2 EIF3D â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
MRPL37 MRPS2 â—¼   PHYSICAL_INTERACTION 817.0 0.81 STRING 36370105
MATR3 COPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 26496610
DHX30 MCMBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
AHSA1 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
ADRM1 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGFR MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
FXR2 G3BP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29395067 24778252
LRP1 GFPT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CUL1 MATR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 21145461
NASP HAT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26496610
HDAC2 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30737378 26949739
AURKB NAT10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29568061 31586073
CUL1 CCNA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 9663463
CCNA1 MCM6 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
KIF23 CD2AP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
CDC16 IQCB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ARRB2 FLNB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MEPCE CAPZB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17643375 29845934
FTSJ3 NOP56 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
EIF2S1 EIF3D â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
EIF2S1 EIF3E â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
EIF2B1 EIF2S1 â—¼   GTPASE_REACTION ✅ + 0.82 0.82 Signor 15054402
MRPS2 MRPS30 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
MATR3 DDX3X â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 FUBP3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
JMJD6 CPSF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24667498
DHX8 JMJD6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DNAJC11 IMMT â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CDC40 EIF4A3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DDX3X FUS â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
CAP1 CFL1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
EIF3C EIF5B â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
COX2 EGFR â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15282306 24797263
DDX3X EIF3G â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
CTNNB1 IQGAP1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DHX8 EIF4A3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
EGFR GAPDH â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DDX3X EIF3D â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
DDX3X EIF3E â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
HDAC2 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25241761 11641274
MCMBP MCM6 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24299456
G3BP2 NUP62 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19615732 26186194
MEPCE CAND1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 17643375
DDX3X EIF3D â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22863883 18628297
DDX3X EIF3E â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29395067 18628297
DDX3X EIF3C â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 18628297 22323517
MEPCE NOP56 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17643375 26496610
NOP56 DHX37 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 26496610
FLNB FLNC â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 22863883 19293945
HNRNPD HNRNPU â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
EGFR ARRB2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
FAF2 ACAD9 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26389662 26186194 32877691
ACAD9 NFS1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 32877691
FUBP1 FUBP3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29395067 33961781 26344197
CUL1 FBXO7 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CHUK MAP3K7 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EFTUD2 EIF4A3 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
GATAD2B HDAC1 â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
GATAD2B HDAC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CTNNB1 HDAC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CTNNB1 JUP â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
NAT10 NOP56 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ANXA1 EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20029029 15581623 31980649 24189400
EGFR LRP1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649 28065597
MATR3 FUS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27460707 27731383 29884807 26496610
KIF23 ARF3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10506747 16713569 31586073
CTNNB1 FBXW11 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
CCT7 ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CCT7 DNM2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DNAJA1 BCS1L â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
ALB IMMT â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
IMMT EEF1A1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FBP1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 30616754 25043030
HIF1A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17273746 11641274 16511565 21148070 24015760
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
MCMBP MCM6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24299456 25036637 22540012 26496610 24190967 17296731 26344197
EIF4G2 EIF2S2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 29530922 16932749
MAP3K2 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10085062 14636585
GAPDH ANXA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
FLNB ARIH1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19270716 12582176 16009940
EIF2S1 EIF3G â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
FBXW11 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 25609649
EIF2S1 EIF3C â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
ACSL3 ACSL4 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 22939629 26496610
NOP56 NAT10 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 34079125 26496610
NOP56 DDX10 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 34079125 26496610
EIF3G EIF5B â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EIF2S2 EIF5B â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
EIF2S2 EIF3C â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
HAT1 NASP â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
EIF3E EIF3G â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 17403899 33961781 24981860 26186194 22939629 26344197
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
MRPL37 MRPS30 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
DDX3X EFTUD2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
MCM6 MCMBP â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
EIF3C EIF3D â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 18599441 22190034 22863883 33961781 24981860 23623729 22939629 26344197
DHX8 EFTUD2 â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
EIF3D EIF3G â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 9822659 22190034 33961781 24981860 26186194 22939629
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
EIF3E EIF3D â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 18599441 28514442 17403899 22190034 22863883 33961781 24981860 20890303 23623729 22939629 26344197
EIF3C EIF3E â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 18599441 17403899 10504338 22863883 33961781 24981860 23623729 22939629 26344197
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
PAIP1 PABPC1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 9548260 6547765
CUL1 FBXW11 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CDC40 DHX8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
PABPC1 PAIP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
DDX23 EFTUD2 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CFL1 LIMK1 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
EIF2S2 EIF3G â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
EIF3C EIF3G â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 18599441 16189514 9822659 33961781 24396066 26186194 24981860 22939629 26344197
EIF2B1 EIF2S2 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
EIF2B1 EIF2S1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
EIF3C EIF3D â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3D EIF3G â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3C EIF3G â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3C EIF3E â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CDC40 EFTUD2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CCT4 CCT7 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CHUK IKBKG â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3E EIF3G â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3D EIF3E â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
COPA GBF1 â—¼   PHYSICAL_INTERACTION 17.0 1.0 Reactome 1680566 16926190 22013193 8505331 10318838 17451557 1631136 17360540 9751720 21844168 8132710 9114004 10921873 1957170 1898986 22304919 16940185
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
EGFR CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19104148 27401557 15371335 16099633 22558232 30747223 12040186 26509276 24816560 12740122 25500543 17318191 19568798 21423209 14585353 34227224 23640056 17496910 17052462 24240237 25164010 14517306 21903109 22200182 16952352 20858269 28035485 9233779
EGFR ANXA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 15581623 31980649 3020049 24782913 2457390 24189400 9223619 17081983 20029029 16052208 22792315 24103589
MAPK1 GORASP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 19651622 17081983 18767875 20068231 17287340 16713569 19413330 11408587
IKBKG CHUK â—¼   PHYSICAL_INTERACTION 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
IKBKG CHUK â—¼   SHARES_COMPLEX 17.0 1.0 ACSN 11340079 12133805 12799363 15199157 15485931 16818229 17363905 17485448 17693255 18716620 20138012 20300203 20531300 21217011 22435554 23430059 28462531
MAP3K7 IKBKG â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10391247 11280761 11460167 11477091 12620219 14633987 14660645 15082531 15125833 16603398 16799562 17301840 17363905 18264787 18641653 19161412 20164171 21041997 21133840 21232017 22941947 23681101 24403530 24699077 24958845
MAP3K7 IKBKG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 50.0 1.0 Omnipath 24911653 11477091 17301840 18180283 19909372 15125833 24699077 17363905 16356855 18641653 24403530 18079694 18223652 14514672 17496917 19531477 20300203 11325957 21133840 21232017 18264787 9744859 10391247 16799562 15836773 10702308 23109003 12620219 14633987 17363973 19161412 22941947 23681101 17047224 29145629 11280761 16301747 15082531 26192618 14660645 20038579 24958845 15327770 20164171 11460167 16603398 21041997
IKBKG CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 74.0 1.0 Omnipath 17145710 17485448 16938294 11865184 11877453 16970925 22435554 17244613 17568778 17363905 16818229 15084594 15485931 24369075 20300203 21217011 12799363 23180781 14743216 16319058 21703539 19666608 20098747 12612076 16126728 15218526 23430059 9751060 20138012 18716620 20368414 10837071 25355947 15836773 23109003 20531300 17702576 17363973 15214841 12459277 17561400 21640763 16285893 28462531 12709429 10968790 15199157 26192618 12133805 16497931 11864612 17693255 17072322 11340079
IQGAP1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15655247 11319218 8226933 1330321 1497021909368021 16135787 17563371 7992057 8248196
IQGAP1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12446675 9694656 11734550 12377780 16622255 10473551
MAPK1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
MAP3K2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 8226933 15315965 17052767 11971971
MAPK1 CAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10659854 12438317 15890648
MAPK1 MCL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12223490 18220336 15241487 25324174 16543145 18676833
MAPK1 CTTN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10537323 21079800 17570479 22514278 20444238
MAPK1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 16954218 10551817 18519666 18687685 26784107
MCL1 CHUK â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 12847084 15592525 17462996 18641653 19392652 19509052 21133840 21232017 23430059 23850759 24378531 26587781
CHUK MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 Reactome 20300203 9744859 17047224 11460167 17496917 14514672
MAP3K7 CHUK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 17145710 14960582 16893890 15836773 33895773 12547194 25241761 24911653 2547194 9742107 18949366 11274345 20200282 20194509 10094049 18855897 10187861
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
AURKB KIF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28992084 31881080 23940115 25512391
AURKB NSUN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 25233213 22395603 17215513
AURKB KIF23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15630414 30728176 16461284 25512391 19203582 15854913 20451386
CCNE1 CUL1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
CUL1 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10228155 10713156 10023660
CUL1 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
EIF2S1 EIF2B1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2B1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2B1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2B1 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2B1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S2 EIF2B1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   SHARES_COMPLEX 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
EIF2S1 EIF2S2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 12601012 12667446 16246152 23850759
CHUK FBXW11 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 9346238 15340381 16303288 8706131
HIF1A ENO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 8955077 15459207
HIF1A GAPDH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19828020 12193088 15967517 21338575 11955624 15132953
HIF1A HSP90B1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19828020 15620698
LIMK1 CFL1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 10652353 11698448 21178402 9655398
LIMK1 CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 74.0 1.0 Omnipath 11784854 16456544 10559936 17522712 25814227 8079118 9655398 17853892 11418599 16713569 19413330 18079118 27153537 19424295 23093407 18578522 12963706 20068231 10592173 11925442 10436159 11340065 18491316 18669648 22154077 11413130 12361576 15866889 11950587 19651622 20058876 18702456 16278681 25784483 15220930 29605806 10613909 20133759 10461188
AP1G1 DNM2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
AP1G1 DNM2 â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
DDX3X PABPC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18596238 21883093 22872150
FBXW11 CTNNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 23331499 9784611 22682247 10074433