Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
PABPC1 GSPT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6539744 18256688
MAPK1 PPP2R5C â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 16456541 5218298
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
PPP2R5C PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16456541 5218298
PPP2R5C PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
UPF1 CASC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19478851 1000120
NCBP2 NCBP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
NEDD8 PPP2R2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PPP2R2C PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R5E PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
PPP2R2A PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
PPP2R5A PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
PPP2R5D PPP2R1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8208439 17540176
PPP2R5A PPP2R1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219546 17245430
PPP2R2A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1328247 19114990
PPP2R5A PPP2CA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8287037 7592815
RBM8A MAGOH â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
SYMPK CSTF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10669729
CSTF2 CPSF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6802478 18688255
SYMPK CPSF2 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 6802478 18688255
FIP1L1 CPSF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TARDBP FUS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNPS1 UPF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11546874 15231747
PCF11 CLP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10357856 10371034
UPF3B UPF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12718880 5216341
ACIN1 PNN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NXT2 NXF3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
DAZL DAZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216016 12511597
DAZAP1 GPR171 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CASC3 UPF2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ALYREF NCBP1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
RNPS1 SRRM1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
SMG5 SMG7 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 29395067 14636577 23348841
PPP1CB SSU72 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
PPP2CB PPP2R5A â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
FIP1L1 PAPOLA â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
PAPOLA SYMPK â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
PAPOLA WDR33 â—¼   PHYSICAL_INTERACTION 809.0 0.81 STRING 36370105
BRCA1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
NXF1 PCF11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22658674 29395067
RBM8A SMG7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20371770 16452507
CPSF4 CSTF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 24981860
VCAM1 CPSF7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
VCAM1 FUS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22623428 19738201
PPP2R1A PPP2R3A â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CPSF2 PCF11 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CPSF3 PAPOLA â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
NXF1 CASC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22658674 33961781
RAD52 TP53BP1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
RNPS1 UPF1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
PPP2R5B PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 5218298 16456541
NXT1 NXF1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 23299939
CSTF1 CSTF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 11459828 10669729 26344197
SRRM1 FUS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 12581738
CPSF3 CSTF2T â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CAND1 CUL5 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
MAGOH MAGOHB â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
PPP2R1B PPP2R2B â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
UPF2 UPF3A â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CASC3 EIF4A3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
NXF1 NXT2 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
CSTF2 CSTF1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10669729 26344197
SYMPK CSTF3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 29395067 26496610
RNPS1 WDR33 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 33961781
CPSF1 CSTF2 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CPSF1 PAPOLA â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CAND1 CUL5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21249194 31253590 12504025 21145461 22405651
ITCH CPSF6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 16055720 26508657
RBM8A NXF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11707413 11546874
NXF1 GLE1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29395067 33961781
NXF1 CPSF7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34133714 22658674 29395067
CPSF3 SYMPK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18688255 26344197 26496610 24981860
CPSF4 CPSF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26344197 24981860
CPSF6 CPSF7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26496610 33961781 24981860 22939629
SYMPK CPSF4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26496610 33961781 24981860 26344197
CPSF4 WDR33 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 24981860 29274231 26344197
RNPS1 SRRM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 33961781 16713569
SMG5 UPF1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
PPP2CB PPP2R5C â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CPSF6 CPSF7 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
FIP1L1 PCF11 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CPSF3 SSU72 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CSTF2 CSTF2T â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RNPS1 UPF3B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
BRCA1 CSTF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11257228 10477523
SMG1 RBM8A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20371770 19417104 16452507
RNPS1 SNRPA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 26496610
PPP2R2A PPP2R2D â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
RBM8A PYM1 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 24981860
RNPS1 CPSF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 26496610
SAP18 RNPS1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16537548 22388736 33961781 26344197 12665594
PCF11 CLP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
DAZ1 DAZL â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10903443 12511597 10857750
PPP1CA PPP1CB â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CSTF2 FIP1L1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PPP2R1B PPP2R2D â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
PPP1CB PPP1CC â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
NUDT21 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
PPP2CA PPP2R2B â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RNPS1 SAP18 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CSTF1 BRCA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29180510 11257228 11278247
SMG1 SMG7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31732746 29395067 16452507
PPP2R1A CFTR â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
CFTR PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5217765 15936019
PPP2R1B PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 8392071 8286818
RBM8A RNPS1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 11707413 23084401
CPSF3 CPSF4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26496610 24981860
CPSF3 CSTF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18688255 24981860 26496610
CPSF2 WDR33 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939629 33961781 26344197 24981860
CPSF1 SYMPK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29395067 26344197 24981860 26496610
SYMPK WDR33 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29395067 26344197 24981860 26496610
NXT2 NXF3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 16189514 25416956 33961781 21516116 11073998
NXT1 NXF3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 16189514 25416956 34133714 33961781 19060904 11073998
CASC3 UPF1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CSTF2T SYMPK â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
COPS5 CUL4B â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
CSTF3 PAPOLA â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
GSPT1 GSPT2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
PNN RNPS1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CAND1 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31973889 28225217 26496610 25435324 12504026 12609982 21145461 34026424
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
PPP2CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
CAND1 CUL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 21778237 12609982 12504026 18173839 22405651
CASC3 RBM8A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16601204 20479275 19478851 16209946 16931718 26496610 16170325 22522823 16923391 18066079
CAND1 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 17290223 12504025 25435324 12504026 12609982 17439941 21145461 22474075 23019411 28715492 22767593 17438373 12706828 23453757 22013077 18173839 22405651 16036220 29499133 21249194 18826954 21169563 15537541 21778237 27542266 29103612 16861300 12684064
CAND1 CUL1 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 12504025 12504026 15537541
CUL3 CAND1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21249194 16449638 22013077 12609982 21145461 22405651 26286618
PPP2R1A PPP2CB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15936019 16039140
MAPK6 PPP2R1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP1CA PPP1CC â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
CPSF2 SYMPK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18288197 26496610 33961781 24981860 29395067 18688255 26344197
CPSF1 CPSF4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 24981860 29540792 29395067 29358758 26344197
SF1 FUS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9660765 16713569
CSTF3 WDR33 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
PPP2R2A PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 20711181 8288198
UPF3B RBM8A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 12718880 5216341
SMG6 UPF1 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
CSTF1 CSTF2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
PPP2CB PPP2R2B â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
GSPT1 SMG1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
PABPC1 SMG1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
GSPT2 SMG1 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
NCBP2 SMG1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PPP1CC WDR82 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
ACIN1 SAP18 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
NXF3 NXT2 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CAND1 CUL3 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
NXF3 NXT1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
COPS5 CUL3 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
UPF1 UPF3B â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
PPP2R1A PPP2CB â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 5217765 15936019
NXF1 NXT2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 28514442 16189514 16713569 33961781 11073998
CPSF3 WDR82 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
PPP1CB WDR82 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CSTF2T FIP1L1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
CPSF2 PAPOLA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CSTF1 CSTF2T â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
CPSF2 CPSF4 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
PPP2R5C PPP2CA â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 6549523 1328865
CSTF2 CPSF1 â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 10669729 26344197
CSTF2 SYMPK â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CSTF3 PCF11 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ETF1 SMG1 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
CPSF3 CSTF2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
COPS5 NEDD8 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
PPP1CA WDR82 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
CPSF2 CSTF1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
PPP2R1B PPP2R5E â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CPSF2 WDR82 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CPSF1 WDR82 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CPSF4 SSU72 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
FIP1L1 SSU72 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
SSU72 WDR33 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
SSU72 WDR82 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CPSF4 WDR82 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
SYMPK WDR82 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
FIP1L1 WDR82 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
WDR33 WDR82 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
CAND1 CUL2 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CASC3 MAGOHB â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
PPP2R1B PPP2R5C â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
PPP2CB PPP2R5E â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
CPSF3 CPSF2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22939629 26496610 33961781 24981860 18688255 26344197
CPSF3 WDR33 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22939629 26344197 26496610 24981860
CPSF1 CPSF2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 24981860 29395067 22939629 33469008 26344197
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
ETF1 GSPT2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
PPP2R1B PPP2R5D â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
ALYREF DDX39B â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CPSF2 SSU72 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
CPSF1 SSU72 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
PPP2R1A PPP2R2B â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
CPSF1 CSTF3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
EIF4A3 MAGOHB â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
CPSF2 CSTF2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
UPF2 UPF1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17469741 5219891
PPP2R2A PPP2R1A â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17245430 5219546
CSTF2 CPSF2 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 18688255 10669729 26344197
SYMPK SSU72 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 27880917 20861839
CLP1 PCF11 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
CSTF2 CSTF3 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CSTF3 PAPOLB â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PNN SAP18 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DDX19B GLE1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
CSTF1 CSTF3 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
PPP2CB PPP2R2D â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
NCBP2 NCBP1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL1 CAND1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17290223 5219620
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
CPSF1 CPSF3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 26496610 24981860 22939629 33469008 26344197
CSTF2 CSTF3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 16713569 22939629 10669729 26344197
CPSF1 WDR33 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22939629 24981860 29540792 29395067 29274231 29358758 26344197
PPP2CB PPP2R1B â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
PPP2R1B PPP2R2A â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CAND1 CUL4B â—¼   PHYSICAL_INTERACTION 962.0 0.96 STRING 36370105
ACIN1 RNPS1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
COPS5 CUL2 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CPSF3 CPSF4 â—¼   PHYSICAL_INTERACTION 964.0 0.96 STRING 36370105
CPSF7 NUDT21 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CPSF2 FIP1L1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
COPS5 CUL1 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
NCBP2 NCBP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 23665581 9933612 26382858 31467278 11545740 22365833 26496610 29395067 12374755 26264872 7478990 19668212 22939629 29997244 32814053 29101316 24981860 31448526 17190602 12434151 26344197
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
NXF1 NXT1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11256625 16189514 25416956 16713569 17978099 11583626 23299939 16314397 33961781 29395067 11073998 26344197
SYMPK CSTF2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16713569 26496610 33961781 24981860 29395067 10669729
FIP1L1 WDR33 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
SMG1 UPF1 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 23356578
CPSF3 FIP1L1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EIF4A3 UPF3B â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CSTF2T CSTF3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MAGOH UPF3B â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
CASC3 UPF3B â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
FIP1L1 SYMPK â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CPSF3 WDR33 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CPSF1 FIP1L1 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CSTF3 FIP1L1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
RBM8A MAGOH â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 24981860
CPSF6 NUDT21 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
GSPT1 PABPC1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
GSPT2 PABPC1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CSTF3 SYMPK â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
CPSF1 CPSF3 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
EIF4A3 MAGOH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CPSF1 SYMPK â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CPSF4 SYMPK â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
SYMPK WDR33 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
EIF4A3 SMG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MAGOH SMG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RBM8A SMG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMG1 UPF3A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMG1 UPF3B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMG1 UPF2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMG1 SMG7 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RBM8A UPF1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PPP2R1A PPP2R1B â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PABPC1 RBM8A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCBP2 RBM8A â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RBM8A UPF2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RBM8A SMG7 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SMG1 UPF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
EIF4A3 UPF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
PPP2R1A PPP2R3B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
CPSF2 WDR33 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
ETF1 GSPT1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
SMG7 UPF1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
MAGOHB RBM8A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CASC3 MAGOH â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF4A3 RBM8A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CASC3 RBM8A â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NCBP1 NCBP2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
NXF1 NXT1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
CPSF1 CPSF2 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
SSU72 SYMPK â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PPP2R1A PPP2R5C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CAND1 CUL1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CB PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1B PPP2R5A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1B PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R5A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2R1A PPP2R2A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R5E â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R2C â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R5D â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PPP2CA PPP2R5B â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
HBS1L PELO â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MAGOH RBM8A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CPSF2 CPSF3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CPSF3 SYMPK â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CPSF1 CPSF4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CPSF4 FIP1L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CPSF4 WDR33 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
GSPT1 UPF1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
GSPT2 UPF1 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CB PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R2A â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
PPP2CA PPP2R2D â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
UPF1 UPF2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CB PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PPP2CA PPP2R3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RBM8A UPF3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CPSF2 SYMPK â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CPSF1 WDR33 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BRCA1 RAD52 â—¼   PHYSICAL_INTERACTION 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 RAD52 â—¼   SHARES_COMPLEX 35.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
PPP1CA BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 25056273 12438214 17511879 17603999
CUL4B COPS5 â—¼   DEMETHYLATION ✅ 9.0 1.0 Reactome 19748355 18926707 16401342 18093314 23535663 23583660 22959436 16943200 23535662
MAPK1 CUL1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
PPP2CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12624094 12840032 18039929 16680151 16456541 10995457 18042541 10592173 7780739 18588945 2154696 20626350
PPP2CB MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 18039929 16680151 16456541 10995457 18042541 7780739 18588945 2154696
MAPK1 DAZAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 24452013 16848763
MAPK1 PPP2R5C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16456541
PPP2CA PPP2R5C â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
PPP2R5C PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 18782753 15380617 1328865 28330616 16456541 11929880 10675325 19156129 8703017 7592815
UPF1 SMG1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 11544179 11331269 19359157 19417104 16452507 14636577 20817927
SMG1 UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29768215 24115769 11544179 11331269 25535763 25013172 23356578 19417104 21965535 18423202 15175154 23826386
UPF2 UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 17145710 19478851 11544179 18256688 11073994 19150429 17469741 20371770 24778252 16452507 11163187 16086026 19503078 18066079 12723973 16488880 19556969 12417715 21145460 19417104 14527413
UPF3B UPF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17145710 18066079 12723973 11163187 19417104
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
CSTF3 CSTF2T â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24149845 10357856 10669729 10371034
NUDT21 CPSF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 16189514 25416956
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CAND1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 45.0 1.0 Omnipath 17145710 12684064 25435324 36076154 23019411 18826954 17290223 17438373 21169563 27542266 16036220 21145461 21778237 22474075 22767593 16861300 18173839 12504026 12504025 12706828 22405651 21249194 23453757 22013077 17439941 12609982 15537541
PPP2R1B PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18715871 17540176 19114990
PPP2R1A PPP2CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 21159657 23443559 19818709 19293187 24841198 28330616 18715871 19915589 18782753 33633399 17274953 26496610 17540176 15761952 17374643 17529992 22379092 17055435 8617797 12370081 17632056 16039140 16769727 19156129
PPP2CA PPP2R5A â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
CSTF2 CSTF1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 24149845 10357856 10669729 10371034
SYMPK CSTF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10669729 21896654 16713569
UPF2 UPF3B â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105